妊娠期肝内胆汁淤积症（Intrahepatic cholestasis of pregnancy ICP）,或称妊娠瘙痒症,是一种以肝功能异常、皮肤瘙痒和胆汁酸增高等为主要症状的妊娠并发症,常见于妊娠中晚期[1],目前病因尚不明,主要危及胎儿,可导致孕期羊水污染、胎...妊娠期肝内胆汁淤积症（Intrahepatic cholestasis of pregnancy ICP）,或称妊娠瘙痒症,是一种以肝功能异常、皮肤瘙痒和胆汁酸增高等为主要症状的妊娠并发症,常见于妊娠中晚期[1],目前病因尚不明,主要危及胎儿,可导致孕期羊水污染、胎儿窘迫、甚至胎死宫内等严重后果,对妊娠结局产生不利影响。多器官功能障碍综合征（multiple organ dysfunction syndrome,MODS）是指在严重创伤、休克和感染时,展开更多
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating Syst...Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System (MARS) has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.展开更多
文摘妊娠期肝内胆汁淤积症（Intrahepatic cholestasis of pregnancy ICP）,或称妊娠瘙痒症,是一种以肝功能异常、皮肤瘙痒和胆汁酸增高等为主要症状的妊娠并发症,常见于妊娠中晚期[1],目前病因尚不明,主要危及胎儿,可导致孕期羊水污染、胎儿窘迫、甚至胎死宫内等严重后果,对妊娠结局产生不利影响。多器官功能障碍综合征（multiple organ dysfunction syndrome,MODS）是指在严重创伤、休克和感染时,
文摘Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System (MARS) has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.
