Children undergoing surgery with infant-onset epilepsy were classified into t hose with medically refractory infantile spasms(IS), successfully treated IS, an d no IS history, and the groups were compared for pre-and ...Children undergoing surgery with infant-onset epilepsy were classified into t hose with medically refractory infantile spasms(IS), successfully treated IS, an d no IS history, and the groups were compared for pre-and postsurgery clinical and Vineland Ad aptive Behavior Scale (VABS) developmental quotients(DQ). Children without an IS history were older at surgery and had longer epilepsy durations than those with IS despite similar substrates, surgeries, and seizure frequencies. In all group s, better postsurgery VABS-DQ scores were associated with early surgical interv ention indicating that infant-onset epilepsy patients with or without IS are at risk for seizure-induced encephalopathy.展开更多
文摘Children undergoing surgery with infant-onset epilepsy were classified into t hose with medically refractory infantile spasms(IS), successfully treated IS, an d no IS history, and the groups were compared for pre-and postsurgery clinical and Vineland Ad aptive Behavior Scale (VABS) developmental quotients(DQ). Children without an IS history were older at surgery and had longer epilepsy durations than those with IS despite similar substrates, surgeries, and seizure frequencies. In all group s, better postsurgery VABS-DQ scores were associated with early surgical interv ention indicating that infant-onset epilepsy patients with or without IS are at risk for seizure-induced encephalopathy.
