Purpose:To determine the exophthalmos measurements in patients with Graves’disease(GD)and to compare with those of normal subjects among the Chinese of Taiwan.Methods:Hertel’s exophthalmometry were performed in 163 ...Purpose:To determine the exophthalmos measurements in patients with Graves’disease(GD)and to compare with those of normal subjects among the Chinese of Taiwan.Methods:Hertel’s exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects.The values of exophthalmos,asymmetry,and the distance between lateral orbital rims(base)were evaluated.Results:There was a significant difference between GD and normal adults for exophthalmos and asymmetry,with GD patients demonstrating a mean exophthalmos of 18.32mm and asymmetry of 0.93mm as compared with 13.91 and 0.55 mm for normal subjects(P< 0.001).The mean value of base for GD adults(106.52 mm)is slightly greater than normal subjects(105.82 mm).There was no gender difference in exophthalmometric value or asymmetry in each group.A total of 79(48.5%)GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan(18.6 mm).Asymmetry over 2 mm was observed in 11(6.7%)patients with GD but in none of the normal subjects.Conclusions:GD patients have significant exophthalmos and asymmetry compared to normal subjects.In comparison with previous studies,exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people,but are close to those of Korean,Japanese,Iranian,Indian,and Asian-American people.Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.展开更多
文摘Purpose:To determine the exophthalmos measurements in patients with Graves’disease(GD)and to compare with those of normal subjects among the Chinese of Taiwan.Methods:Hertel’s exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects.The values of exophthalmos,asymmetry,and the distance between lateral orbital rims(base)were evaluated.Results:There was a significant difference between GD and normal adults for exophthalmos and asymmetry,with GD patients demonstrating a mean exophthalmos of 18.32mm and asymmetry of 0.93mm as compared with 13.91 and 0.55 mm for normal subjects(P< 0.001).The mean value of base for GD adults(106.52 mm)is slightly greater than normal subjects(105.82 mm).There was no gender difference in exophthalmometric value or asymmetry in each group.A total of 79(48.5%)GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan(18.6 mm).Asymmetry over 2 mm was observed in 11(6.7%)patients with GD but in none of the normal subjects.Conclusions:GD patients have significant exophthalmos and asymmetry compared to normal subjects.In comparison with previous studies,exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people,but are close to those of Korean,Japanese,Iranian,Indian,and Asian-American people.Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.
