目的探讨Masquelet技术与Ilizarov技术治疗感染性骨不愈合的疗效。方法本研究收集在山西医科大学第二医院创伤骨科使用Masquelet技术和使用Ilizarov技术治疗的感染性骨不愈合患者30例,男19例,女11例;年龄20~65岁,平均(32.6±11.22)...目的探讨Masquelet技术与Ilizarov技术治疗感染性骨不愈合的疗效。方法本研究收集在山西医科大学第二医院创伤骨科使用Masquelet技术和使用Ilizarov技术治疗的感染性骨不愈合患者30例,男19例,女11例;年龄20~65岁,平均(32.6±11.22)岁。12例采用Masquelet技术,18例采用Ilizarov技术。统计治疗时间、治疗费用、手术数量、并发症及疗效评价,分析并比较两种技术的优劣。结果两组均获随访。Ilizarov技术组随访时间平均(18.04±3.67)个月,愈合时间平均(19.22±3.52)个月。Masquelet技术组随访时间平均(17.07±2.69)个月,愈合时间平均(6.00±2.17)个月。两组手术费用比较,差异有统计学意义( P <0.05);总手术次数比较,差异无统计学意义( P >0.05);控制感染手术次数及骨重建手术次数比较,差异有统计学意义( P <0.05)。结论目前的医疗水平及技术条件,两种术式均可以治疗感染性骨不愈合,但两种术式均有其明显的优缺点。Ilizarov技术可以不用顾忌骨缺损数量,可彻底控制感染;且该技术只需少量植骨或不需要植骨,对周围软组织环境要求较低。而Masquelet技术受制于骨缺损,不仅需要大量植骨,而且不能彻底清创,对损伤软组织需求较高,植皮常常为必要步骤;但其费用低、手术次数少,在治疗过程中更有利于患者。展开更多
Abstract： Long bone septic non-union by MRSA （methicillin-resistant Staphylococcus aureus） is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods a...Abstract： Long bone septic non-union by MRSA （methicillin-resistant Staphylococcus aureus） is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods and vascularised bone grafting. These techniques require a high level of expertise and are frequently involved with a variety of side effects or complications. We present a rare case of ulnar fracture complicated by MRSA infection that led to septic non-union. We treated the septic non union with the technique of induced membrane formation （Masquelet technique）. A 33 year old male presented to the outpatient clinic, 2 months after internal fixation of a Gustillo I fracture of the left forearm. There was pus discharge from the operative wound and specimen culture was positive for MRSA. Initially the patient received conservative treatment with antibiotics for a period of one month. However, the patient returned with the same clinical presentation. The patient was then treated with hardware removal of the ulna and debridement of the septic non-union. The formed 5 cm bone defect was filled with cement spacer and the ulnar bone was fixed with external fixation. Eight weeks later, the spacer was removed and the bone gap was filled with autologous cancellous bone graft from iliac crest. Five months after grafting, the patient was reviewed. No clinical or functional problems were noted and osseous consolidation of the ulnar bone was confirmed in plain x-rays. The Masquelet technique is a promising alternative treatment for the management of infected long bone non-unions of the upper extremity.展开更多
文摘目的探讨Masquelet技术与Ilizarov技术治疗感染性骨不愈合的疗效。方法本研究收集在山西医科大学第二医院创伤骨科使用Masquelet技术和使用Ilizarov技术治疗的感染性骨不愈合患者30例,男19例,女11例;年龄20~65岁,平均(32.6±11.22)岁。12例采用Masquelet技术,18例采用Ilizarov技术。统计治疗时间、治疗费用、手术数量、并发症及疗效评价,分析并比较两种技术的优劣。结果两组均获随访。Ilizarov技术组随访时间平均(18.04±3.67)个月,愈合时间平均(19.22±3.52)个月。Masquelet技术组随访时间平均(17.07±2.69)个月,愈合时间平均(6.00±2.17)个月。两组手术费用比较,差异有统计学意义( P <0.05);总手术次数比较,差异无统计学意义( P >0.05);控制感染手术次数及骨重建手术次数比较,差异有统计学意义( P <0.05)。结论目前的医疗水平及技术条件,两种术式均可以治疗感染性骨不愈合,但两种术式均有其明显的优缺点。Ilizarov技术可以不用顾忌骨缺损数量,可彻底控制感染;且该技术只需少量植骨或不需要植骨,对周围软组织环境要求较低。而Masquelet技术受制于骨缺损,不仅需要大量植骨,而且不能彻底清创,对损伤软组织需求较高,植皮常常为必要步骤;但其费用低、手术次数少,在治疗过程中更有利于患者。
文摘Abstract： Long bone septic non-union by MRSA （methicillin-resistant Staphylococcus aureus） is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods and vascularised bone grafting. These techniques require a high level of expertise and are frequently involved with a variety of side effects or complications. We present a rare case of ulnar fracture complicated by MRSA infection that led to septic non-union. We treated the septic non union with the technique of induced membrane formation （Masquelet technique）. A 33 year old male presented to the outpatient clinic, 2 months after internal fixation of a Gustillo I fracture of the left forearm. There was pus discharge from the operative wound and specimen culture was positive for MRSA. Initially the patient received conservative treatment with antibiotics for a period of one month. However, the patient returned with the same clinical presentation. The patient was then treated with hardware removal of the ulna and debridement of the septic non-union. The formed 5 cm bone defect was filled with cement spacer and the ulnar bone was fixed with external fixation. Eight weeks later, the spacer was removed and the bone gap was filled with autologous cancellous bone graft from iliac crest. Five months after grafting, the patient was reviewed. No clinical or functional problems were noted and osseous consolidation of the ulnar bone was confirmed in plain x-rays. The Masquelet technique is a promising alternative treatment for the management of infected long bone non-unions of the upper extremity.
