为研究火箭基组合循环发动机(Rocket Based Combined Cycle,RBCC)进气道隔离段内激波串传播规律,利用数值模拟研究分析了在高、低反压作用下总收缩比变化对激波串驻留位置及流动分离区范围的影响,并进一步开展了总收缩比对进气道气动性...为研究火箭基组合循环发动机(Rocket Based Combined Cycle,RBCC)进气道隔离段内激波串传播规律,利用数值模拟研究分析了在高、低反压作用下总收缩比变化对激波串驻留位置及流动分离区范围的影响,并进一步开展了总收缩比对进气道气动性能影响的仿真研究。研究结果表明:在承受额定反压作用下,进气道总收缩比存在临界值,在临界值下提高总收缩比能显著增强进气道抗反压能力,并影响激波串驻留位置。在临界值上提高总收缩比对进气道抗反压能力无明显作用,进气道流动状态不受总收缩比变化的影响。此外,提高总收缩比能显著提高被捕获冲压空气流所承受的压缩程度,但会承受额外的空气流量损失和气动阻力。展开更多
Scale effect is one of the important aspects in the macro mechanical parame- ters’ research of rock mass, from a new point of view, by means of lab and field rock me- chanics test, establishment of E^Vp relation, cla...Scale effect is one of the important aspects in the macro mechanical parame- ters’ research of rock mass, from a new point of view, by means of lab and field rock me- chanics test, establishment of E^Vp relation, classification of engineering rock mass, nu- merical simulation test and back analysis based on surrounding rock’s displacement monitoring results of Shuibuya Project’s underground power station, rock mass deforma- tion module’s size effect of surrounding rock of Shuibuya Project’s undegroud power sta- tion was studied. It’s shown that rock mass deformation module’s scale effect of sur- rounding rock of Shuibuya Project’s undeground power station is obvious, the rock mass deformation module to tranquilization is 20% of intact rock’s. Finally the relation between rock mass deformation modules and the scale of research was established.展开更多
Purpose： Renal denervation （RD） has been demonstrated to be an effective approach to reduce blood pressure for those with resistant hypertension. Yet, we aimed to explore the effect and possible mech- anism of RD o...Purpose： Renal denervation （RD） has been demonstrated to be an effective approach to reduce blood pressure for those with resistant hypertension. Yet, we aimed to explore the effect and possible mech- anism of RD on blood-pressure response to hemorrhagic shock in spontaneously hypertensive rats. Methods： A total of 48 male spontaneously hypertensive rats were randomized to three groups： study group, sham-operation group and control group. RD was achieved by cutting off renal nerves and swabbing phenol on it. Ten weeks after RD, 8 rats in each group were sacrificed to collect the kidney and heart tissues. The remaining rats were subjected to an operation to induce hemorrhagic shock which would lead to 40% loss of total blood volume, and observed for 120 min. The serum concentration of norepinephrine was measured before and three weeks after RD. Results： The blood-pressure and norepinephrine levels were reduced significantly after RD （p 〈 0.05）, Systolic blood pressure and diastolic blood pressure of the surgerygroup were higher than those in the sham and control groups at 15, 30 and 45 min after hemorrhagic shock （p 〈 0.05）, while no significant difference was observed at 60, 90 and 120 min （p 〉 0.05）. Additionally, the beta-1 adrenergic receptor （β1 -AR） in the study group was significantly higher than those in the other two groups （p 〈 0.05） after hemorrhagic shock. Conclusion： This study demonstrated that RD could to some extent improve blood-pressure response to hemorrhagic shock in an established model of severe hemorrhagic shock in spontaneously hypertensive rats. The mechanism might be associated with uo-regulation of β1-AR.展开更多
文摘为研究火箭基组合循环发动机(Rocket Based Combined Cycle,RBCC)进气道隔离段内激波串传播规律,利用数值模拟研究分析了在高、低反压作用下总收缩比变化对激波串驻留位置及流动分离区范围的影响,并进一步开展了总收缩比对进气道气动性能影响的仿真研究。研究结果表明:在承受额定反压作用下,进气道总收缩比存在临界值,在临界值下提高总收缩比能显著增强进气道抗反压能力,并影响激波串驻留位置。在临界值上提高总收缩比对进气道抗反压能力无明显作用,进气道流动状态不受总收缩比变化的影响。此外,提高总收缩比能显著提高被捕获冲压空气流所承受的压缩程度,但会承受额外的空气流量损失和气动阻力。
文摘Scale effect is one of the important aspects in the macro mechanical parame- ters’ research of rock mass, from a new point of view, by means of lab and field rock me- chanics test, establishment of E^Vp relation, classification of engineering rock mass, nu- merical simulation test and back analysis based on surrounding rock’s displacement monitoring results of Shuibuya Project’s underground power station, rock mass deforma- tion module’s size effect of surrounding rock of Shuibuya Project’s undegroud power sta- tion was studied. It’s shown that rock mass deformation module’s scale effect of sur- rounding rock of Shuibuya Project’s undeground power station is obvious, the rock mass deformation module to tranquilization is 20% of intact rock’s. Finally the relation between rock mass deformation modules and the scale of research was established.
文摘Purpose： Renal denervation （RD） has been demonstrated to be an effective approach to reduce blood pressure for those with resistant hypertension. Yet, we aimed to explore the effect and possible mech- anism of RD on blood-pressure response to hemorrhagic shock in spontaneously hypertensive rats. Methods： A total of 48 male spontaneously hypertensive rats were randomized to three groups： study group, sham-operation group and control group. RD was achieved by cutting off renal nerves and swabbing phenol on it. Ten weeks after RD, 8 rats in each group were sacrificed to collect the kidney and heart tissues. The remaining rats were subjected to an operation to induce hemorrhagic shock which would lead to 40% loss of total blood volume, and observed for 120 min. The serum concentration of norepinephrine was measured before and three weeks after RD. Results： The blood-pressure and norepinephrine levels were reduced significantly after RD （p 〈 0.05）, Systolic blood pressure and diastolic blood pressure of the surgerygroup were higher than those in the sham and control groups at 15, 30 and 45 min after hemorrhagic shock （p 〈 0.05）, while no significant difference was observed at 60, 90 and 120 min （p 〉 0.05）. Additionally, the beta-1 adrenergic receptor （β1 -AR） in the study group was significantly higher than those in the other two groups （p 〈 0.05） after hemorrhagic shock. Conclusion： This study demonstrated that RD could to some extent improve blood-pressure response to hemorrhagic shock in an established model of severe hemorrhagic shock in spontaneously hypertensive rats. The mechanism might be associated with uo-regulation of β1-AR.
