In November 2000, we became aware of isolates of Staphylococcus aureus with borderline resistance to oxacillin (BORSA) from patients in the Department of Dermatology, Aarhus University Hospital. The objective was to d...In November 2000, we became aware of isolates of Staphylococcus aureus with borderline resistance to oxacillin (BORSA) from patients in the Department of Dermatology, Aarhus University Hospital. The objective was to describe the isolates phenotypically and genotypically and to assess possible transmission routes in order to intervene and prevent further spread. Clonality of the isolates was confirmed by pulsed field gel electrophoresis. Several breaches in infection control procedures were revealed suggesting both direct and indirect transmission between patients. Defective skin barriers, high carrier rates of S. aureus in dermatological patients and high consumption rates of dicloxacillin in the department might facilitate transmission. Following improvement of the general infection control measures, and after reassessment of the antibiotic policy in the department, the outbreak has disappeared.展开更多
心肌梗死患者的病死率较高，既往人们通过观察左室射血分数的变化来判断心肌梗死患者的危险分层。文献报道，反映自主神经功能的标志物对判断心肌梗死患者的危险分层有一定意义。压力反射敏感性降低是否可预测左室功能尚可的心肌梗死患...心肌梗死患者的病死率较高，既往人们通过观察左室射血分数的变化来判断心肌梗死患者的危险分层。文献报道，反映自主神经功能的标志物对判断心肌梗死患者的危险分层有一定意义。压力反射敏感性降低是否可预测左室功能尚可的心肌梗死患者的长期预后，意大利的De Ferrari GM等进行了研究，结果发表在J Am Coll Cardiol上。展开更多
文摘In November 2000, we became aware of isolates of Staphylococcus aureus with borderline resistance to oxacillin (BORSA) from patients in the Department of Dermatology, Aarhus University Hospital. The objective was to describe the isolates phenotypically and genotypically and to assess possible transmission routes in order to intervene and prevent further spread. Clonality of the isolates was confirmed by pulsed field gel electrophoresis. Several breaches in infection control procedures were revealed suggesting both direct and indirect transmission between patients. Defective skin barriers, high carrier rates of S. aureus in dermatological patients and high consumption rates of dicloxacillin in the department might facilitate transmission. Following improvement of the general infection control measures, and after reassessment of the antibiotic policy in the department, the outbreak has disappeared.
文摘心肌梗死患者的病死率较高，既往人们通过观察左室射血分数的变化来判断心肌梗死患者的危险分层。文献报道，反映自主神经功能的标志物对判断心肌梗死患者的危险分层有一定意义。压力反射敏感性降低是否可预测左室功能尚可的心肌梗死患者的长期预后，意大利的De Ferrari GM等进行了研究，结果发表在J Am Coll Cardiol上。
