Background:Tufted angioma, a peculiar angioma that is characterized by tufts of capillary-sized vessels scattered ‘cannon-ball fashion’within the dermis, is known, on occasion, to regress spontaneously. However, the...Background:Tufted angioma, a peculiar angioma that is characterized by tufts of capillary-sized vessels scattered ‘cannon-ball fashion’within the dermis, is known, on occasion, to regress spontaneously. However, the appropriate waiting period for spontaneous regression has remained unclear. Objective:To know the appropriate waiting period for spontaneous regression of tufted angioma. Methods:We report here a case of tufted angioma that regressed spontaneously after the lesions had recurred twice. We also review previously reported cases of tufted angioma with spontaneous regression, including cases in the Japanese and non- Japanese literature. Results:In 18 (86%) of the 21 cases, the waiting period was more than 6 months and in 20 cases (95%) it was less than 2 years. Conclusion:The appropriate wait for spontaneous regression might be between 6 months and 2 years.展开更多
Erythema induratum (EI)/nodular vasculitis (NV) is characterized by recurrent crops of tender oedematous nodules on the lower legs. A lobular panniculitis with granulomatous inflammation, vasculitis, focal necrosis an...Erythema induratum (EI)/nodular vasculitis (NV) is characterized by recurrent crops of tender oedematous nodules on the lower legs. A lobular panniculitis with granulomatous inflammation, vasculitis, focal necrosis and septal fibrosis is present. Mycobacterium tuberculosis DNA has been detected in some lesionsbymeansofpolymerasechainreaction(PCR).Tencases of EI/NV were found. H& E slides were reviewed. PCR assays for M.tuberculosis and mycobacteria other than M.tuberculosis (MOTT) were performed. PCR did not reveal M. tuberculosis (0% ) or MOTT (0% ) DNA, with positive controls, indicating the reliability of the assays. Among the MOTT, cutaneous infections are most commonly caused by M. marinum. Subcutaneous tuberculoid granulomas may be seen with M. kansasii, M. marinum, M. scrofulaceum and M. avium complex. M. gordonae, M. szulgai and M. malmoense rarely cause cutaneous infections. M. simiae, M. gastri and M. asiaticum are probably not cutaneous pathogens. M. tuberculosis and MOTT DNA was not found in EI/NV. EI/NV has diverse aetiologies with varying pathogeneses leading to similar histologic changes. The cases analysed may not have had an infectious aetiology. However, in EI/NV, performance of PCR for MOTT as well as M. tuberculosis complex may still be beneficial, particularly in cases from immunocompromised hosts.展开更多
The Recovery Plan Workbook is designed for use by U.S. Army chemical installations and state and local authorities who participate in the Chemical Stockpile Emergency Preparedness Program (CSEPP).The workbook includes...The Recovery Plan Workbook is designed for use by U.S. Army chemical installations and state and local authorities who participate in the Chemical Stockpile Emergency Preparedness Program (CSEPP).The workbook includes a model recovery plan that provides a template for preparation of an integrated CSEPP recovery plan.展开更多
文摘Background:Tufted angioma, a peculiar angioma that is characterized by tufts of capillary-sized vessels scattered ‘cannon-ball fashion’within the dermis, is known, on occasion, to regress spontaneously. However, the appropriate waiting period for spontaneous regression has remained unclear. Objective:To know the appropriate waiting period for spontaneous regression of tufted angioma. Methods:We report here a case of tufted angioma that regressed spontaneously after the lesions had recurred twice. We also review previously reported cases of tufted angioma with spontaneous regression, including cases in the Japanese and non- Japanese literature. Results:In 18 (86%) of the 21 cases, the waiting period was more than 6 months and in 20 cases (95%) it was less than 2 years. Conclusion:The appropriate wait for spontaneous regression might be between 6 months and 2 years.
文摘Erythema induratum (EI)/nodular vasculitis (NV) is characterized by recurrent crops of tender oedematous nodules on the lower legs. A lobular panniculitis with granulomatous inflammation, vasculitis, focal necrosis and septal fibrosis is present. Mycobacterium tuberculosis DNA has been detected in some lesionsbymeansofpolymerasechainreaction(PCR).Tencases of EI/NV were found. H& E slides were reviewed. PCR assays for M.tuberculosis and mycobacteria other than M.tuberculosis (MOTT) were performed. PCR did not reveal M. tuberculosis (0% ) or MOTT (0% ) DNA, with positive controls, indicating the reliability of the assays. Among the MOTT, cutaneous infections are most commonly caused by M. marinum. Subcutaneous tuberculoid granulomas may be seen with M. kansasii, M. marinum, M. scrofulaceum and M. avium complex. M. gordonae, M. szulgai and M. malmoense rarely cause cutaneous infections. M. simiae, M. gastri and M. asiaticum are probably not cutaneous pathogens. M. tuberculosis and MOTT DNA was not found in EI/NV. EI/NV has diverse aetiologies with varying pathogeneses leading to similar histologic changes. The cases analysed may not have had an infectious aetiology. However, in EI/NV, performance of PCR for MOTT as well as M. tuberculosis complex may still be beneficial, particularly in cases from immunocompromised hosts.
文摘The Recovery Plan Workbook is designed for use by U.S. Army chemical installations and state and local authorities who participate in the Chemical Stockpile Emergency Preparedness Program (CSEPP).The workbook includes a model recovery plan that provides a template for preparation of an integrated CSEPP recovery plan.
