随着人们对新生儿黄疸认识的深入及医疗机构对新生儿高胆红素血症的规范管理,极重型新生儿高胆红素血症目前在临床并不常见,该病在诊断上并不困难,但发现时已是极重型高胆红素血症,易发展为胆红素脑病,造成神经系统损伤,严重影响新生儿...随着人们对新生儿黄疸认识的深入及医疗机构对新生儿高胆红素血症的规范管理,极重型新生儿高胆红素血症目前在临床并不常见,该病在诊断上并不困难,但发现时已是极重型高胆红素血症,易发展为胆红素脑病,造成神经系统损伤,严重影响新生儿今后生长发育及健康,因此治疗上需光疗联合其他多种治疗措施,尽快将胆红素降低至安全阈值以下,减少胆红素脑病的发生。本病例患儿胆红素水平达到极重型,经过光疗,静脉输注白蛋白、免疫球蛋白、补液等治疗措施,早期积极干预,迅速降低了患儿胆红素水平,避免了胆红素脑病的发生,预后良好。With the deepening of people’s understanding of neonatal jaundice and the standardized management of neonatal hyperbilirubinemia by medical institutions, extremely severe neonatal hyperbilirubinemia is not common in clinical practice. The disease is not difficult to diagnose, but when it is discovered, it is already extremely severe hyperbilirubinemia, which is prone to develop into bilirubin encephalopathy and cause nervous system damage. Therefore, phototherapy combined with other multiple treatment measures is required for treatment to reduce bilirubin to below the safe threshold as soon as possible and reduce the occurrence of bilirubin encephalopathy. The bilirubin level of the child in this case reached an extremely severe level. After phototherapy, intravenous infusion of albumin, immunoglobulin, fluid infusion and other treatment measures, early active intervention quickly reduced the bilirubin level of the child, avoided the occurrence of bilirubin encephalopathy, and had a good prognosis.展开更多
目的:对近15年新生儿高胆红素血症的相关研究进行文献计量学及可视化分析,探讨其研究现状和热点前沿,为该领域以后的研究提供一定参考.方法:检索2009年1月至2024年1月收录的新生儿高胆红素血症的相关文献1746篇供本研究分析,以Web of Sc...目的:对近15年新生儿高胆红素血症的相关研究进行文献计量学及可视化分析,探讨其研究现状和热点前沿,为该领域以后的研究提供一定参考.方法:检索2009年1月至2024年1月收录的新生儿高胆红素血症的相关文献1746篇供本研究分析,以Web of Science(WOS)核心合集为文献来源,使用VOSviewer和CiteSpace软件对国家、期刊、关键词等进行分析,并生成图表.结果:分析得出发文量最多的国家是美国,发文量最多且共被引最多的期刊是PEDIATRICS;关键词分析发现光疗、核黄疸、经皮测胆红素、换血疗法等是出现频数较高的关键词.结论:近15年研究热点主要集中于病因、发病机制和治疗等方面,并逐渐细化,推测未来会得到持续关注.展开更多
文摘随着人们对新生儿黄疸认识的深入及医疗机构对新生儿高胆红素血症的规范管理,极重型新生儿高胆红素血症目前在临床并不常见,该病在诊断上并不困难,但发现时已是极重型高胆红素血症,易发展为胆红素脑病,造成神经系统损伤,严重影响新生儿今后生长发育及健康,因此治疗上需光疗联合其他多种治疗措施,尽快将胆红素降低至安全阈值以下,减少胆红素脑病的发生。本病例患儿胆红素水平达到极重型,经过光疗,静脉输注白蛋白、免疫球蛋白、补液等治疗措施,早期积极干预,迅速降低了患儿胆红素水平,避免了胆红素脑病的发生,预后良好。With the deepening of people’s understanding of neonatal jaundice and the standardized management of neonatal hyperbilirubinemia by medical institutions, extremely severe neonatal hyperbilirubinemia is not common in clinical practice. The disease is not difficult to diagnose, but when it is discovered, it is already extremely severe hyperbilirubinemia, which is prone to develop into bilirubin encephalopathy and cause nervous system damage. Therefore, phototherapy combined with other multiple treatment measures is required for treatment to reduce bilirubin to below the safe threshold as soon as possible and reduce the occurrence of bilirubin encephalopathy. The bilirubin level of the child in this case reached an extremely severe level. After phototherapy, intravenous infusion of albumin, immunoglobulin, fluid infusion and other treatment measures, early active intervention quickly reduced the bilirubin level of the child, avoided the occurrence of bilirubin encephalopathy, and had a good prognosis.
文摘目的:对近15年新生儿高胆红素血症的相关研究进行文献计量学及可视化分析,探讨其研究现状和热点前沿,为该领域以后的研究提供一定参考.方法:检索2009年1月至2024年1月收录的新生儿高胆红素血症的相关文献1746篇供本研究分析,以Web of Science(WOS)核心合集为文献来源,使用VOSviewer和CiteSpace软件对国家、期刊、关键词等进行分析,并生成图表.结果:分析得出发文量最多的国家是美国,发文量最多且共被引最多的期刊是PEDIATRICS;关键词分析发现光疗、核黄疸、经皮测胆红素、换血疗法等是出现频数较高的关键词.结论:近15年研究热点主要集中于病因、发病机制和治疗等方面,并逐渐细化,推测未来会得到持续关注.
