A precursor of BaCe 0.9 Nd 0.1 O 3-δ solid electrolyte was synthesized by the sol-gel method and sintered at14 00℃.The obtained gels and powder were characterized by differential and ther mogravimetric thermal analy...A precursor of BaCe 0.9 Nd 0.1 O 3-δ solid electrolyte was synthesized by the sol-gel method and sintered at14 00℃.The obtained gels and powder were characterized by differential and ther mogravimetric thermal analysis(TG-DTA),X-ray diffraction(XRD),transmissi on electron microscopy(TEM).Using the sintered samples as solid electrolyte a nd silver-palladium alloy as electrodes,electrical conductivities under differ ent gas ambiences at intermediate temperature(400～600℃)were measured. In moist hydrogen atmosphere,the conduction is a little higher than that of dry hydrogen atmosphere.In hydrogen atmosphere,proton conduction may predominate ,leading to an increase in conductivity and a decrease in activation energy.展开更多
本研究旨在探讨单采血小板模式下柠檬酸盐抗凝剂的应用对机体骨代谢平衡的短期影响,为可能的干预手段提供参考,更好地保护献血者健康。采用自身交叉、安慰剂对照的研究模式,对22名健康献血志愿者以标准化的干预方式分别给予1.5mg/(kg...本研究旨在探讨单采血小板模式下柠檬酸盐抗凝剂的应用对机体骨代谢平衡的短期影响,为可能的干预手段提供参考,更好地保护献血者健康。采用自身交叉、安慰剂对照的研究模式,对22名健康献血志愿者以标准化的干预方式分别给予1.5mg/(kg·min)的柠檬酸盐抗凝剂(ACD-A)和相同容量的安慰剂(生理盐水)输注,干预洗脱期为2-3周。干预过程中采集系列血样进行骨代谢相关指标,包括骨形成指标骨钙素(osteocalcin,OC)、骨吸收指标Ⅰ型胶原蛋白C端肽(carboxyterminal telopeptide of type Ⅰcollagen,CTX)、全段甲状旁腺素(intact parathyroid hormone,iPTH),以及游离钙离子(ionized calcium,iCa2+)和无机磷(phosphorus,Pi)的检测,采集系列尿样进行尿钙、尿磷和尿肌酐的检测。结果表明:与对照组比较,柠檬酸盐干预导致:①血清OC和CTX水平大幅升高(p<0.0001),并于干预结束时升高至最高点,其中CTX增幅高于OC(p=0.02),OC/CTX比值降低(p<0.01);②血清iPTH水平升高(p<0.0001),iCa2+(p<0.0001)和Pi(p<0.01)水平降低,尿钙排出增加(p<0.0001);③女性iCa2+水平降幅高于男性(p=0.007),但未见iPTH、OC和CTX水平变化的性别间差异;④血清OC水平变化与CTX正相关(r=0.56,p<0.0001),二者均与iCa2+水平变化负相关(rOC=-0.44,rCTX=-0.44,p<0.0001);男性iPTH水平变化与OC相关(r=0.34,p=0.02),女性无此相关性;⑤上述指标24小时后均恢复至初始水平。结论:普通剂量下单次柠檬酸盐抗凝剂的输注可引发机体骨转换率的短暂提升,并以骨吸收增强为主要特征,同时伴随有尿钙排泄的增加,其对长期、频繁单采献血者骨质健康的影响值得关注。展开更多
文摘A precursor of BaCe 0.9 Nd 0.1 O 3-δ solid electrolyte was synthesized by the sol-gel method and sintered at14 00℃.The obtained gels and powder were characterized by differential and ther mogravimetric thermal analysis(TG-DTA),X-ray diffraction(XRD),transmissi on electron microscopy(TEM).Using the sintered samples as solid electrolyte a nd silver-palladium alloy as electrodes,electrical conductivities under differ ent gas ambiences at intermediate temperature(400～600℃)were measured. In moist hydrogen atmosphere,the conduction is a little higher than that of dry hydrogen atmosphere.In hydrogen atmosphere,proton conduction may predominate ,leading to an increase in conductivity and a decrease in activation energy.
文摘本研究旨在探讨单采血小板模式下柠檬酸盐抗凝剂的应用对机体骨代谢平衡的短期影响,为可能的干预手段提供参考,更好地保护献血者健康。采用自身交叉、安慰剂对照的研究模式,对22名健康献血志愿者以标准化的干预方式分别给予1.5mg/(kg·min)的柠檬酸盐抗凝剂(ACD-A)和相同容量的安慰剂(生理盐水)输注,干预洗脱期为2-3周。干预过程中采集系列血样进行骨代谢相关指标,包括骨形成指标骨钙素(osteocalcin,OC)、骨吸收指标Ⅰ型胶原蛋白C端肽(carboxyterminal telopeptide of type Ⅰcollagen,CTX)、全段甲状旁腺素(intact parathyroid hormone,iPTH),以及游离钙离子(ionized calcium,iCa2+)和无机磷(phosphorus,Pi)的检测,采集系列尿样进行尿钙、尿磷和尿肌酐的检测。结果表明:与对照组比较,柠檬酸盐干预导致:①血清OC和CTX水平大幅升高(p<0.0001),并于干预结束时升高至最高点,其中CTX增幅高于OC(p=0.02),OC/CTX比值降低(p<0.01);②血清iPTH水平升高(p<0.0001),iCa2+(p<0.0001)和Pi(p<0.01)水平降低,尿钙排出增加(p<0.0001);③女性iCa2+水平降幅高于男性(p=0.007),但未见iPTH、OC和CTX水平变化的性别间差异;④血清OC水平变化与CTX正相关(r=0.56,p<0.0001),二者均与iCa2+水平变化负相关(rOC=-0.44,rCTX=-0.44,p<0.0001);男性iPTH水平变化与OC相关(r=0.34,p=0.02),女性无此相关性;⑤上述指标24小时后均恢复至初始水平。结论:普通剂量下单次柠檬酸盐抗凝剂的输注可引发机体骨转换率的短暂提升,并以骨吸收增强为主要特征,同时伴随有尿钙排泄的增加,其对长期、频繁单采献血者骨质健康的影响值得关注。
