基金This work was supported by grants from the National Basic Research Program of China （973 Program, No. 2015CB965000）, National Natural Science Foundation of China （Nos. 81400463, 81570911, 81470692, 81230019, 81371094, 81500790, 81570921, 31500852, and 31501194）, J iangsu Province Natural Science Foundation （Nos. BK20150022, BK20140620, and BK20150598）, Fundamental Research Funds for the Central Universities （Nos. 2242014R- 30022 and 021414380037）, the Yingdong Huo Education Founda- tion, the Open Research Funds of the State Key Laboratory of Genetic Engineering, Fudan University （No. SKLGE-1407）, Major Program of Shanghai Committee of Science and Technology （Nos. 14DJ1400203 and 11441901000）, Doctoral Fund of Chinese Ministry of Education （No. 20120071110077）, and China Post- doctoral Science Foundation Funded Project （No. 2014M551328）.
基金This work was supported by grants from Beijing Medical Development Foundation （No. 2002-3075） and China Postdoctoral Science Foundation （No. 20080440224）.
