邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介...邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介绍了ATA在铜绿假单胞菌中的代谢与功能,以及ATA调控青枯雷尔氏菌的生理活动。最后结合其他微生物中ATA的最新研究结果,我们提出ATA可能参与微生物跨界交流。Anthranilic acid (ATA) is a small molecule produced by microorganisms and is an intermediate product of the tryptophan synthesis pathway. In recent years, it has been revealed that ATA is a new signaling molecule and has effects on microbial physiology. In this review, we first briefly outlined the relationship between ATA and tryptophan synthesis in Escherichia coli and Saccharomyces cerevisiae. We then summarized the metabolic network and biological functions of ATA in Pseudomonas aeruginosa, as well as the progress of ATA in regulating the physiology of Ralstonia solanacearum. Finally, we summarized the latest results describing the roles of ATA in other microorganisms and proposed that ATA may play a role in interkingdom communication.展开更多
Two kinds of organic-inorganic comp osite luminescent material were pre pared through sol-gel route,by dopi ng o-amino-benzoic acid(ABA)or N-phenylanthranilic acid(N-PA)into SiO 2 xerogels.Fluorescence properties and ...Two kinds of organic-inorganic comp osite luminescent material were pre pared through sol-gel route,by dopi ng o-amino-benzoic acid(ABA)or N-phenylanthranilic acid(N-PA)into SiO 2 xerogels.Fluorescence properties and thermal properties of ABA and N-PA in SiO 2 xerogels were studied.The relation ship between the fluorescence properties and the preparative cond ition was also studied.The results s howed that the ABA was easy to form dim er of non-luminescence among the molec ules.The quenching concentration o f the ABA was obviously increased owi ng to the shield of silica network.The f luorescence intensity of the composite material prepared at the acid con dition was decreased,and a red shift for the fluorescence peak appeared.With th e increasing of the pH value,the flu-orescence peak blue shifted and the i ntensity was increased.However,th e fluorescent intensity of N-PA /SiO 2 was increasing due to the concentration of N-PA was increased.The thermal stability of ABA and N-PA in the composite material was also improved.But,when the temperature continued to incre ase,the collapse of the silica netwo rk made the organic molecules escape fr om the pore of the silica network,the decomposition of escaping molecule s decreased the intensity of emission spectrum.展开更多
文摘邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介绍了ATA在铜绿假单胞菌中的代谢与功能,以及ATA调控青枯雷尔氏菌的生理活动。最后结合其他微生物中ATA的最新研究结果,我们提出ATA可能参与微生物跨界交流。Anthranilic acid (ATA) is a small molecule produced by microorganisms and is an intermediate product of the tryptophan synthesis pathway. In recent years, it has been revealed that ATA is a new signaling molecule and has effects on microbial physiology. In this review, we first briefly outlined the relationship between ATA and tryptophan synthesis in Escherichia coli and Saccharomyces cerevisiae. We then summarized the metabolic network and biological functions of ATA in Pseudomonas aeruginosa, as well as the progress of ATA in regulating the physiology of Ralstonia solanacearum. Finally, we summarized the latest results describing the roles of ATA in other microorganisms and proposed that ATA may play a role in interkingdom communication.
文摘Two kinds of organic-inorganic comp osite luminescent material were pre pared through sol-gel route,by dopi ng o-amino-benzoic acid(ABA)or N-phenylanthranilic acid(N-PA)into SiO 2 xerogels.Fluorescence properties and thermal properties of ABA and N-PA in SiO 2 xerogels were studied.The relation ship between the fluorescence properties and the preparative cond ition was also studied.The results s howed that the ABA was easy to form dim er of non-luminescence among the molec ules.The quenching concentration o f the ABA was obviously increased owi ng to the shield of silica network.The f luorescence intensity of the composite material prepared at the acid con dition was decreased,and a red shift for the fluorescence peak appeared.With th e increasing of the pH value,the flu-orescence peak blue shifted and the i ntensity was increased.However,th e fluorescent intensity of N-PA /SiO 2 was increasing due to the concentration of N-PA was increased.The thermal stability of ABA and N-PA in the composite material was also improved.But,when the temperature continued to incre ase,the collapse of the silica netwo rk made the organic molecules escape fr om the pore of the silica network,the decomposition of escaping molecule s decreased the intensity of emission spectrum.
