甲状旁腺激素(parathyroid hormone,PTH)是由甲状旁腺分泌的具有调节血钙磷代谢及骨健康的重要激素,在慢性肾脏病-矿物质骨异常(chronic kidney disease-mineral and bone disorder,CKDMBD)的发生发展中起着核心作用。了解PTH的体...甲状旁腺激素(parathyroid hormone,PTH)是由甲状旁腺分泌的具有调节血钙磷代谢及骨健康的重要激素,在慢性肾脏病-矿物质骨异常(chronic kidney disease-mineral and bone disorder,CKDMBD)的发生发展中起着核心作用。了解PTH的体内代谢及检测方法有利于我们正确诊治CKD-MBD。1 PTH的体内合成、展开更多
The kinetics of casein tryptic hydrolysis to prepare activepeptides was investigated. Taking into account the reaction mechanismincluding single substrate hydrolysis, irreversible enzymeinactivation, and substrate inh...The kinetics of casein tryptic hydrolysis to prepare activepeptides was investigated. Taking into account the reaction mechanismincluding single substrate hydrolysis, irreversible enzymeinactivation, and substrate inhibition, a set of exponentialequations was established to characterize the enzymatic hydrolysiscurves. The verification was carried out by a series of experimentalresults and indicated that the average regressive error was less than5/100. According to the proposed kinetic model, the kinetic constantsand thermodynamic constants of the reaction system were alsocalculated.展开更多
文摘甲状旁腺激素(parathyroid hormone,PTH)是由甲状旁腺分泌的具有调节血钙磷代谢及骨健康的重要激素,在慢性肾脏病-矿物质骨异常(chronic kidney disease-mineral and bone disorder,CKDMBD)的发生发展中起着核心作用。了解PTH的体内代谢及检测方法有利于我们正确诊治CKD-MBD。1 PTH的体内合成、
基金Supported by National Natural Science Foundation of China (No. 20276052) and Tianjin Science & Technology Commission (No. 023105411).
文摘The kinetics of casein tryptic hydrolysis to prepare activepeptides was investigated. Taking into account the reaction mechanismincluding single substrate hydrolysis, irreversible enzymeinactivation, and substrate inhibition, a set of exponentialequations was established to characterize the enzymatic hydrolysiscurves. The verification was carried out by a series of experimentalresults and indicated that the average regressive error was less than5/100. According to the proposed kinetic model, the kinetic constantsand thermodynamic constants of the reaction system were alsocalculated.