Objectives: To understand trends and epidemiological featuresof syphilis over the recent years in China and provide a scien-tific basis for developing prevention strategies. Methods: From 1985 to 2000, syphilis case-r...Objectives: To understand trends and epidemiological featuresof syphilis over the recent years in China and provide a scien-tific basis for developing prevention strategies. Methods: From 1985 to 2000, syphilis case-reporting datacollected from all provinces, autonomous regions and munici-palities were analyzed by applying epidemiological methods. Results: (1) Epidemic trends: syphilis incidence has steadilyrisen in China from 1985 to 2000, especially after 1993, when itassumed an exponential growth pattern. 80,406 cases of syphi-lis were reported in the country in 1999, which was almost 40times the number reported in 1993. During the period of1993-1999, the annual average growth of the syphilis incidencerate was 83.55%. Perhaps due to a recent national law en-forcement campaign, the number of reported syphilis casesdropped slightly in 2000. (2) Geographical distribution: Syphi-lis spread from coastal, 'open' cities (especially some cities inFujian province) to inland urban areas, then to rural areas.Regions with a high incidence rate of syphilis in China were theMinjiang, Yangtze, and Zhujiang River Deltas, Beijing andTianjin municipalities, and Northeast China. There was a sig-nificant difference of syphilis incidence rates and growth ratesbetween these areas. A serious epidemic occurred in some ar-eas, with an incidence rate reaching over 200 cases out of100,000. (3) Population distribution: the ratio of male and fe-male cases gradually changed from 1.57:1 in 1993 to 1.02:1 in2000. The rate was the highest in the 20-29 age group and thelowest in 10-14 age group. A great difference existed in preva-lence between different population groups and different areas,and some areas with serious epidemics had high prevalencerates even amoung the general population. (4) Clinical stage ofsyphilis: Primary and secondary syphilis cases have beendominating with a percentage of 90% of all syphilis cases. Pri-mary syphilis was the most common in males and secondarysyphilis in females. Secondary and latent syphilis cases in fe-males were more than in males. (5) The congenital syphilisincidence has increased dramatically. Two cases were reportedin 1991 and 468 cases in 2000. Conclusion: The syphilis epidemic in China became muchmore severe between 1985 and 2000, and such increasingtrends deserve our serious attention.展开更多
Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by HIV It has been epidemic formore than 20 years, but there is no cure of it. Health educationand behavioral interventions are some of the mo...Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by HIV It has been epidemic formore than 20 years, but there is no cure of it. Health educationand behavioral interventions are some of the most effectiveapproaches in the control and prevention of AIDS. China isone of the countries with the fastest growing HIVseroprevalence rate, and is facing a widespread epidemic ofAIDS. Currently, high-risk populations such as individualswith multiple sexual partners and intravenous drug users arethe main foci of health education and behavioral interventionsin China. Encouraging results have been observed in manyforms of health education and behavioral intervention. Theapplication of health education and behavioral interventionsmust emerge from scientific evidence, follow a series ofstrategies, be carried out from various perspectives, andrequire the participation of all societal communities.展开更多
Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas...Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas andbeauty parlors were trained as interviewers. They surveyedclients during provision of sexual services. Informationcollected included customers' demographics, knowledge ofSTDs, rationale for and history of condom use. Risk factorsfor condom usage were assessed though logistical modeling.Results: A total of 50 clients were interviewed. The rates ofcondom usage for last sexual intercourse with commercial andnon-commercial partners were 57% and 53% for clients ofsauna centers and 30% and 40% for clients of beauty parlors,respectively. The choice to use a condom was influenced byclients 60.8% of the time, sex workers 30.4%, and otherfactors 8.8%. The choice against using a condom was decidedupon by clients 69.7% of the time, sex workers 9.1%, andother factors 21.2%. Multivariate analysis showed thateducational level and perception of risk of infection werefactors for condom use. Clients with a high school educationhad a higher condom use rate than those with a middle schooleducation or less. Furthermore, clients who perceived risk ofdisease used condoms more frequently than those who did not.Conclusions: Clients played a significant role in decidingwhether or not to use a condom during commercial sex. Lackof perception of risk is a major factor for not using condoms.A program for promotion of prophylactics targeting bothcommercial sex workers and their clients is recommended.展开更多
United Nations Political Declaration 2011 on HIV and AIDS calls to reduce the sexual transmission and the transmission of HIV among people, who inject drugs by 50% by 2015, through different control strategies and pre...United Nations Political Declaration 2011 on HIV and AIDS calls to reduce the sexual transmission and the transmission of HIV among people, who inject drugs by 50% by 2015, through different control strategies and precautionary measures. In this paper, we propose and study a simple SI type model that considers the effect of various precaution- ary measures to control HIV epidemic. We show, unlike conventional epidemic models, that the basic reproduction number which essentially considered as the disease eradica- tion condition is no longer sufficient to eliminate HIV infection. In particular, we show that even when the basic reproduction number is made less than unity, the disease may persist if the initial outbreak is not low. Eradication of disease is however guaranteed if the ensemble control measure exceeds some upper critical value. It is also shown that an epidemic model with mass action incidence may exhibit backward bifurcation and bistability if density-dependent demography is considered. Our theoretical study thus indicates that extra attention should be given in controlling HIV epidemic to achieve the desired result.展开更多
文摘Objectives: To understand trends and epidemiological featuresof syphilis over the recent years in China and provide a scien-tific basis for developing prevention strategies. Methods: From 1985 to 2000, syphilis case-reporting datacollected from all provinces, autonomous regions and munici-palities were analyzed by applying epidemiological methods. Results: (1) Epidemic trends: syphilis incidence has steadilyrisen in China from 1985 to 2000, especially after 1993, when itassumed an exponential growth pattern. 80,406 cases of syphi-lis were reported in the country in 1999, which was almost 40times the number reported in 1993. During the period of1993-1999, the annual average growth of the syphilis incidencerate was 83.55%. Perhaps due to a recent national law en-forcement campaign, the number of reported syphilis casesdropped slightly in 2000. (2) Geographical distribution: Syphi-lis spread from coastal, 'open' cities (especially some cities inFujian province) to inland urban areas, then to rural areas.Regions with a high incidence rate of syphilis in China were theMinjiang, Yangtze, and Zhujiang River Deltas, Beijing andTianjin municipalities, and Northeast China. There was a sig-nificant difference of syphilis incidence rates and growth ratesbetween these areas. A serious epidemic occurred in some ar-eas, with an incidence rate reaching over 200 cases out of100,000. (3) Population distribution: the ratio of male and fe-male cases gradually changed from 1.57:1 in 1993 to 1.02:1 in2000. The rate was the highest in the 20-29 age group and thelowest in 10-14 age group. A great difference existed in preva-lence between different population groups and different areas,and some areas with serious epidemics had high prevalencerates even amoung the general population. (4) Clinical stage ofsyphilis: Primary and secondary syphilis cases have beendominating with a percentage of 90% of all syphilis cases. Pri-mary syphilis was the most common in males and secondarysyphilis in females. Secondary and latent syphilis cases in fe-males were more than in males. (5) The congenital syphilisincidence has increased dramatically. Two cases were reportedin 1991 and 468 cases in 2000. Conclusion: The syphilis epidemic in China became muchmore severe between 1985 and 2000, and such increasingtrends deserve our serious attention.
文摘Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by HIV It has been epidemic formore than 20 years, but there is no cure of it. Health educationand behavioral interventions are some of the most effectiveapproaches in the control and prevention of AIDS. China isone of the countries with the fastest growing HIVseroprevalence rate, and is facing a widespread epidemic ofAIDS. Currently, high-risk populations such as individualswith multiple sexual partners and intravenous drug users arethe main foci of health education and behavioral interventionsin China. Encouraging results have been observed in manyforms of health education and behavioral intervention. Theapplication of health education and behavioral interventionsmust emerge from scientific evidence, follow a series ofstrategies, be carried out from various perspectives, andrequire the participation of all societal communities.
基金This study was supported by China National Center for AIDS Prevention and Control and Peking Union School of Public Health.
文摘Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage centers. Methods: Selected female sex workers from saunas andbeauty parlors were trained as interviewers. They surveyedclients during provision of sexual services. Informationcollected included customers' demographics, knowledge ofSTDs, rationale for and history of condom use. Risk factorsfor condom usage were assessed though logistical modeling.Results: A total of 50 clients were interviewed. The rates ofcondom usage for last sexual intercourse with commercial andnon-commercial partners were 57% and 53% for clients ofsauna centers and 30% and 40% for clients of beauty parlors,respectively. The choice to use a condom was influenced byclients 60.8% of the time, sex workers 30.4%, and otherfactors 8.8%. The choice against using a condom was decidedupon by clients 69.7% of the time, sex workers 9.1%, andother factors 21.2%. Multivariate analysis showed thateducational level and perception of risk of infection werefactors for condom use. Clients with a high school educationhad a higher condom use rate than those with a middle schooleducation or less. Furthermore, clients who perceived risk ofdisease used condoms more frequently than those who did not.Conclusions: Clients played a significant role in decidingwhether or not to use a condom during commercial sex. Lackof perception of risk is a major factor for not using condoms.A program for promotion of prophylactics targeting bothcommercial sex workers and their clients is recommended.
文摘United Nations Political Declaration 2011 on HIV and AIDS calls to reduce the sexual transmission and the transmission of HIV among people, who inject drugs by 50% by 2015, through different control strategies and precautionary measures. In this paper, we propose and study a simple SI type model that considers the effect of various precaution- ary measures to control HIV epidemic. We show, unlike conventional epidemic models, that the basic reproduction number which essentially considered as the disease eradica- tion condition is no longer sufficient to eliminate HIV infection. In particular, we show that even when the basic reproduction number is made less than unity, the disease may persist if the initial outbreak is not low. Eradication of disease is however guaranteed if the ensemble control measure exceeds some upper critical value. It is also shown that an epidemic model with mass action incidence may exhibit backward bifurcation and bistability if density-dependent demography is considered. Our theoretical study thus indicates that extra attention should be given in controlling HIV epidemic to achieve the desired result.
