Soil Moisture and Ocean Salinity （SMOS） Level 3 （L3） sea surface salinity （SSS） products are provided by the Barcelona Expert Centre （BEC）. Strong biases were observed on the SMOS SSS products, thus the data f...Soil Moisture and Ocean Salinity （SMOS） Level 3 （L3） sea surface salinity （SSS） products are provided by the Barcelona Expert Centre （BEC）. Strong biases were observed on the SMOS SSS products, thus the data from the Centre Aval de Traitement des Donnees SMOS （CATDS） were adjusted for biases using a large-scale correction derived from observed differences between the SMOS SSS and World Ocean Atlas （WOA） climatology data. However, this large-scale correction method is not suitable for correcting the large gradient of salinity biases. Here, we present a method for the correction of SSS regional bias of the monthly L3 products. Based on the stable characteristics of the large SSS biases from month to month in some regions, corrected SMOS SSS maps can be obtained from the monthly mean values after removing the regional biases. The accuracy of the SMOS SSS measurements is greatly improved, especially near the coastline, at high latitudes, and in some open ocean regions. The SMOS and ISAS SSS data are also compared with Aquarius SSS to verify the corrected SMOS SSS data. The correction method presented here only corrects annual mean biases. The measurement accuracy of the SSS may be improved by considering the influence of atmospheric and ocean circulation in different seasons and years.展开更多
Caspase-1-mediated IL-1β production is generally controlled by two pathways. Toll-like receptors （TLRs） recognize pathogen-derived products and induce NF-KB-dependent pro-IL-1β transcription; NOD-like receptors （...Caspase-1-mediated IL-1β production is generally controlled by two pathways. Toll-like receptors （TLRs） recognize pathogen-derived products and induce NF-KB-dependent pro-IL-1β transcription; NOD-like receptors （NLRs） assemble caspase-l-activating inflammasome complexes that sense bacterial products/danger signals. Through a targeted chemical screen, we identify bromoxone, a marine natural product, as a specifc and potent inhibitor of the caspase-1 pathway. Bromoxone is effective over diverse inflammatory stimuli including TLR ligands plus ATP/nigeri- cin, cytosolic DNA, flagellin and Bacillus anthracis lethal toxin. Bromoxone also efficiently suppresses easpase-1 acti- vation triggered by several types of bacterial infection. Bromoxone acts upstream or at the level of the inflammasome in a transcription-independent manner. Bromoxone also inhibits pro-IL-1β expression by targeting components up- stream of IKK in the TLR-NF-kB pathway. The unique dual activities of bromoxone are shared by the known TAK1 inhibitor that specifically blocks Nalp3 inflammasome activation. Hinted from the mechanistic and pharmacological properties of bromoxone, we further discover that several known NF-KB inhibitors that act upstream of IKK, but not those targeting IKK or IKK downstream, are potent blockers of different NLRs-mediated caspase-1 activation. Our study uncovers a possible non-transcriptional molecular link between the NLR （Nalp3）-mediated inflammasome pathway and TLR-NF-kB signaling, and suggests a potential strategy to develop new anti-inflammatory drugs.展开更多
A field study was conducted to investigate the effect of Aquasap, a commercially manufactured biostimulant from seaweed Kappapphycus alvarezii on some hills and foothills banana varieties namely Robusta （AAA）, Njali...A field study was conducted to investigate the effect of Aquasap, a commercially manufactured biostimulant from seaweed Kappapphycus alvarezii on some hills and foothills banana varieties namely Robusta （AAA）, Njali poovan （AB）, Red banana （AAA） and Nendran （AAB） by applying at 5% through foliar spray at the 3rd, 5th and 7th month of plantation. Both quantitative and quality data of fruits were analyzed along with vegetative growth of the plants. The seaweed biostimulant was found very effective on increasing the weight and nutritional contents of all four banana varieties tested. The highest yield was found in Robusta with 56.58% over control followed by Njali poovan, Red banana and Nendran with 19.08%, 39.35% and 11.46%, respectively. Yield of fruits per hectare of four varieties treated were 76.96, 19.23, 29.68 and 23.37 metric ton （mt）, respectively. Fruits of treated plants also showed less moisture level as compared to control with 240.61%, 62.30%, 61.68% and 37.18% more carbohydrate, 283.71%, 94.07%, 62.87% and 38.93% higher proteins and 153.02%, 47.37%, 58.73% and 31.48% higher minerals respectively as compare to control plants. Therefore, the simple practice of application of eco-friendly seaweed based biostimulant would benefit small and marginal farmers of banana.展开更多
Coastal date palm cultivars are interesting through their soft dates, their abundant and earliest production than continental cultivars. Maintaining bio-diversity in Tunisian oases has become a subject of first intere...Coastal date palm cultivars are interesting through their soft dates, their abundant and earliest production than continental cultivars. Maintaining bio-diversity in Tunisian oases has become a subject of first interest in date palm cultivation in Tunisia. Coastal oases still retain a very rich and varied plant biodiversity in comparison with the continental oases, weakened by the mono cultivation of ＂Deglet Nour＂ cultivar. Study of soft date＇s composition can make there well known to date consumers, help to valorize there and to help of sustainability of coastal oases ecosystem. Fresh dates from 15 cultivars was collected, dried by 80 ~C in 20-24 h. Acidity was determinate by pH meter. Sugars were appreciated by enzymatic method. Ash and minerals was calculated by photometer and spectrometer. Chemical date composition study showed that coastal date palm cultivars are predominantly rich of carbohydrates, have a low quantity of sucrose which gives them an important dietary value. Their pH varies from 5 to 6, classifies them as the best date quality for fresh consumption. Their richness in Total Nitrogen Matters and total minerals makes them at almost the same level as the other date palm eultivars analyzed by different authors in different areas of date palm production. Mineral composition showed that these dates are K and P-rich and relatively poor in Na and Ca.展开更多
The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively...The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively. An osmotic dehydration treatment is necessary to improve the quality of the final product for maintaining its integrity. Thus, it is a preservation technique that is often used as pretreatment to obtain partially dehydrated fruit. In this experimental study, the cultivar date Lemsi were cut into cubes of 1 cm3 and were immersed in sucrose solutions of 50%, 60% and 70% at 20℃ for 0-240 min. The moisture content, the solute gain, the water loss and the ratio WL/SG are determined and discussed. The results deduced from this work have showed that sugar gain SG, water loss WL and the ratio WL/SG are increased with concentration of osmotic solution. Likewise, the osmotic dehydration treatment need to be followed of a convective drying to ensure the quality of the final product.展开更多
Marine invertebrates and fish are well known for their remarkable genetic diversity, which is commonly explained by large population size and the characteristic dispersive nature of their early, planktonic life histor...Marine invertebrates and fish are well known for their remarkable genetic diversity, which is commonly explained by large population size and the characteristic dispersive nature of their early, planktonic life history. Other potential sources of diversity in marine animals, such as a higher mutation rate, have been much less considered, though evidence for a high genetic load in marine bivalves has been accumulating for nearly half a century. In this review, I examine evidence for a higher genetic load in marine animals from studies of molecular marker segregation and linkage over the last 40 years, and survey recent work examining mutational load with molecular evolution approaches. Overall, marine animals appear to have higher genetic load than terrestrial animals （higher dn/ds ratios, inbreeding load, and segregation dis＇tortion）, though results are mixed for marine fish and data are lacking for many marine animal groups. Bivalves （oysters） have the highest loads observed among marine animals, comparable only to long-lived plants; however, more data is needed from other bivalves and more marine invertebrate taxa generally. For oysters, a higher load may be related to a chronically lower effective population size that, in concert with a higher mutational rate, elevate the number of deleterious mutations observed. I suggest that future studies use high-throughput sequencing approaches to examine （1） polymorphism in genomescale datasets across a wider range of marine animals at the population level and （2） intergenerational mutational changes between parents and offspring in crosses of aquaculture species to quantify mutation rates.展开更多
基金Supported by the National Natural Science Foundation of China(No.41076117)
文摘Soil Moisture and Ocean Salinity （SMOS） Level 3 （L3） sea surface salinity （SSS） products are provided by the Barcelona Expert Centre （BEC）. Strong biases were observed on the SMOS SSS products, thus the data from the Centre Aval de Traitement des Donnees SMOS （CATDS） were adjusted for biases using a large-scale correction derived from observed differences between the SMOS SSS and World Ocean Atlas （WOA） climatology data. However, this large-scale correction method is not suitable for correcting the large gradient of salinity biases. Here, we present a method for the correction of SSS regional bias of the monthly L3 products. Based on the stable characteristics of the large SSS biases from month to month in some regions, corrected SMOS SSS maps can be obtained from the monthly mean values after removing the regional biases. The accuracy of the SMOS SSS measurements is greatly improved, especially near the coastline, at high latitudes, and in some open ocean regions. The SMOS and ISAS SSS data are also compared with Aquarius SSS to verify the corrected SMOS SSS data. The correction method presented here only corrects annual mean biases. The measurement accuracy of the SSS may be improved by considering the influence of atmospheric and ocean circulation in different seasons and years.
文摘Caspase-1-mediated IL-1β production is generally controlled by two pathways. Toll-like receptors （TLRs） recognize pathogen-derived products and induce NF-KB-dependent pro-IL-1β transcription; NOD-like receptors （NLRs） assemble caspase-l-activating inflammasome complexes that sense bacterial products/danger signals. Through a targeted chemical screen, we identify bromoxone, a marine natural product, as a specifc and potent inhibitor of the caspase-1 pathway. Bromoxone is effective over diverse inflammatory stimuli including TLR ligands plus ATP/nigeri- cin, cytosolic DNA, flagellin and Bacillus anthracis lethal toxin. Bromoxone also efficiently suppresses easpase-1 acti- vation triggered by several types of bacterial infection. Bromoxone acts upstream or at the level of the inflammasome in a transcription-independent manner. Bromoxone also inhibits pro-IL-1β expression by targeting components up- stream of IKK in the TLR-NF-kB pathway. The unique dual activities of bromoxone are shared by the known TAK1 inhibitor that specifically blocks Nalp3 inflammasome activation. Hinted from the mechanistic and pharmacological properties of bromoxone, we further discover that several known NF-KB inhibitors that act upstream of IKK, but not those targeting IKK or IKK downstream, are potent blockers of different NLRs-mediated caspase-1 activation. Our study uncovers a possible non-transcriptional molecular link between the NLR （Nalp3）-mediated inflammasome pathway and TLR-NF-kB signaling, and suggests a potential strategy to develop new anti-inflammatory drugs.
文摘A field study was conducted to investigate the effect of Aquasap, a commercially manufactured biostimulant from seaweed Kappapphycus alvarezii on some hills and foothills banana varieties namely Robusta （AAA）, Njali poovan （AB）, Red banana （AAA） and Nendran （AAB） by applying at 5% through foliar spray at the 3rd, 5th and 7th month of plantation. Both quantitative and quality data of fruits were analyzed along with vegetative growth of the plants. The seaweed biostimulant was found very effective on increasing the weight and nutritional contents of all four banana varieties tested. The highest yield was found in Robusta with 56.58% over control followed by Njali poovan, Red banana and Nendran with 19.08%, 39.35% and 11.46%, respectively. Yield of fruits per hectare of four varieties treated were 76.96, 19.23, 29.68 and 23.37 metric ton （mt）, respectively. Fruits of treated plants also showed less moisture level as compared to control with 240.61%, 62.30%, 61.68% and 37.18% more carbohydrate, 283.71%, 94.07%, 62.87% and 38.93% higher proteins and 153.02%, 47.37%, 58.73% and 31.48% higher minerals respectively as compare to control plants. Therefore, the simple practice of application of eco-friendly seaweed based biostimulant would benefit small and marginal farmers of banana.
文摘Coastal date palm cultivars are interesting through their soft dates, their abundant and earliest production than continental cultivars. Maintaining bio-diversity in Tunisian oases has become a subject of first interest in date palm cultivation in Tunisia. Coastal oases still retain a very rich and varied plant biodiversity in comparison with the continental oases, weakened by the mono cultivation of ＂Deglet Nour＂ cultivar. Study of soft date＇s composition can make there well known to date consumers, help to valorize there and to help of sustainability of coastal oases ecosystem. Fresh dates from 15 cultivars was collected, dried by 80 ~C in 20-24 h. Acidity was determinate by pH meter. Sugars were appreciated by enzymatic method. Ash and minerals was calculated by photometer and spectrometer. Chemical date composition study showed that coastal date palm cultivars are predominantly rich of carbohydrates, have a low quantity of sucrose which gives them an important dietary value. Their pH varies from 5 to 6, classifies them as the best date quality for fresh consumption. Their richness in Total Nitrogen Matters and total minerals makes them at almost the same level as the other date palm eultivars analyzed by different authors in different areas of date palm production. Mineral composition showed that these dates are K and P-rich and relatively poor in Na and Ca.
文摘The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively. An osmotic dehydration treatment is necessary to improve the quality of the final product for maintaining its integrity. Thus, it is a preservation technique that is often used as pretreatment to obtain partially dehydrated fruit. In this experimental study, the cultivar date Lemsi were cut into cubes of 1 cm3 and were immersed in sucrose solutions of 50%, 60% and 70% at 20℃ for 0-240 min. The moisture content, the solute gain, the water loss and the ratio WL/SG are determined and discussed. The results deduced from this work have showed that sugar gain SG, water loss WL and the ratio WL/SG are increased with concentration of osmotic solution. Likewise, the osmotic dehydration treatment need to be followed of a convective drying to ensure the quality of the final product.
文摘Marine invertebrates and fish are well known for their remarkable genetic diversity, which is commonly explained by large population size and the characteristic dispersive nature of their early, planktonic life history. Other potential sources of diversity in marine animals, such as a higher mutation rate, have been much less considered, though evidence for a high genetic load in marine bivalves has been accumulating for nearly half a century. In this review, I examine evidence for a higher genetic load in marine animals from studies of molecular marker segregation and linkage over the last 40 years, and survey recent work examining mutational load with molecular evolution approaches. Overall, marine animals appear to have higher genetic load than terrestrial animals （higher dn/ds ratios, inbreeding load, and segregation dis＇tortion）, though results are mixed for marine fish and data are lacking for many marine animal groups. Bivalves （oysters） have the highest loads observed among marine animals, comparable only to long-lived plants; however, more data is needed from other bivalves and more marine invertebrate taxa generally. For oysters, a higher load may be related to a chronically lower effective population size that, in concert with a higher mutational rate, elevate the number of deleterious mutations observed. I suggest that future studies use high-throughput sequencing approaches to examine （1） polymorphism in genomescale datasets across a wider range of marine animals at the population level and （2） intergenerational mutational changes between parents and offspring in crosses of aquaculture species to quantify mutation rates.
