AIM:To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma(HCC). METHODS:We retrospectively reviewed the medical records of 140 patients with pathologically p...AIM:To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma(HCC). METHODS:We retrospectively reviewed the medical records of 140 patients with pathologically proven extrahepatic metastases of HCC and evaluated the outcomes of those who had undergone surgical resection(SR)for extrahepatic metastatic lesions.Prognoses made on the basis of extrahepatic metastatic sites were also examined. RESULTS:The survival rates of patients who underwent SR of extrahepatic metastases were significantly better than those of patients who did not receive SR. For the SR group,1-and 3-year survival rates were 24%and 7%,respectively,while for the non-resection group,the survival rates were 8%and 0%,respec- tively(P<0.0001).Survival rates related to metastatic sites were also significantly superior after SR of extrahepatic metastases:median survivals were 32 mo with lung metastasis,10 mo with bone metastasis,6.1 mo with brain metastasis. CONCLUSION:SR can provide survival benefits forpatients with 1 or 2 isolated extrahepatic metastases and who concurrently exhibit good hepatic functional reserve and general performance status as well as successful treatment of intrahepatic HCC.展开更多
The aging of the population is, currently, a major phenomenon, drawing the attention of a number of investigators. The significant increase of life expectancies over the past few decades, in addition to social and eco...The aging of the population is, currently, a major phenomenon, drawing the attention of a number of investigators. The significant increase of life expectancies over the past few decades, in addition to social and economic consequences, has lead to a major change in the morbidity and mortality profile of elders. Heart failure （HF） is a condition in which the heart can not pump enough blood to meet the body＇s needs. HF is predominantly a disorder of the elderly with rates increasing exponentially. The prevalence of HF approximately doubles with each decade of life. As people live longer, the occurrence of HF rises, as well as other conditions that complicate its treatment. Impaired heart function implies a reduced duration of survival. Fortunately, many factors that can prevent HF and improve outcome are known and can be applied at any stage. This review emphasizes the importance of factors inherent in aging itself, focusing on heart disease, particularly as a disease of aging, can help critically refine management of this acute and chronic disease, as well as foster preventive strategies to reduce the incidence of this common malady.展开更多
The m ajor advantages of EBS-based key rrkanagerrent scheme are its enhanced network survivability, high dynamic performance, and better support for network expansion. But it suffers from the collusion problem, which ...The m ajor advantages of EBS-based key rrkanagerrent scheme are its enhanced network survivability, high dynamic performance, and better support for network expansion. But it suffers from the collusion problem, which means it is prone to the cooperative attack of evicted members. A novel EBS-based collusion resistant group management scheme utilizing the construction of Ciphertext-Policy Attribute-Based Encryption （CP-ABE） is proposed. The new scheme satisfies the desired security properties, such as forward secrecy, backward secrecy and collusion secrecy. Compared with existing EBS-based key rmnagement scheme, the new scheme can resolve EBS collusion problem completely. Even all evicted members work together, and share their individual piece of information, they could not access to the new group key. In addition, our scheme is more efficient in terms of conmnication and computation overhead when the group size is large. It can be well controlled even in the case of large-scale application scenarios.展开更多
This work collects the characteristics of the family kits of students from the careers related to health in the Espoch, by identifying their knowledge and habits to determine the relationship between self-medication a...This work collects the characteristics of the family kits of students from the careers related to health in the Espoch, by identifying their knowledge and habits to determine the relationship between self-medication and the possession of medicines contained in the first-aid kit. This is related to the most outstanding frequency （48.1% bedroom） with the use of medicines in the home （48.5% when the treatment ends）. Taking into account that 63.6% do not have a kit, they stored them in inadequate places to control their stability and quality for the use they were made, being analgesics and antibiotics those commonly found during the inspection that took place in the home. This determines that storage habits are not adequate for the proper storage of medications, including having knowledge of health and the importance of proper use by students, being essential to know that medicines must be stored in fresh places and dry, to avoid damage and problems associated with its stability.展开更多
Sustainable development is the basis of survival. The SMEs as an important part of our national economy, plays the role of increasing national income, expanding employment, stabilizing social situation. Under the new ...Sustainable development is the basis of survival. The SMEs as an important part of our national economy, plays the role of increasing national income, expanding employment, stabilizing social situation. Under the new situation, it needs to change the status quo of financial management, financial management to achieve sustainable development of SMEs. This paper is combined with the financial management of the significance of sustainable development as well as financial management problems in the SME financial management strategy.展开更多
文摘AIM:To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma(HCC). METHODS:We retrospectively reviewed the medical records of 140 patients with pathologically proven extrahepatic metastases of HCC and evaluated the outcomes of those who had undergone surgical resection(SR)for extrahepatic metastatic lesions.Prognoses made on the basis of extrahepatic metastatic sites were also examined. RESULTS:The survival rates of patients who underwent SR of extrahepatic metastases were significantly better than those of patients who did not receive SR. For the SR group,1-and 3-year survival rates were 24%and 7%,respectively,while for the non-resection group,the survival rates were 8%and 0%,respec- tively(P<0.0001).Survival rates related to metastatic sites were also significantly superior after SR of extrahepatic metastases:median survivals were 32 mo with lung metastasis,10 mo with bone metastasis,6.1 mo with brain metastasis. CONCLUSION:SR can provide survival benefits forpatients with 1 or 2 isolated extrahepatic metastases and who concurrently exhibit good hepatic functional reserve and general performance status as well as successful treatment of intrahepatic HCC.
文摘The aging of the population is, currently, a major phenomenon, drawing the attention of a number of investigators. The significant increase of life expectancies over the past few decades, in addition to social and economic consequences, has lead to a major change in the morbidity and mortality profile of elders. Heart failure （HF） is a condition in which the heart can not pump enough blood to meet the body＇s needs. HF is predominantly a disorder of the elderly with rates increasing exponentially. The prevalence of HF approximately doubles with each decade of life. As people live longer, the occurrence of HF rises, as well as other conditions that complicate its treatment. Impaired heart function implies a reduced duration of survival. Fortunately, many factors that can prevent HF and improve outcome are known and can be applied at any stage. This review emphasizes the importance of factors inherent in aging itself, focusing on heart disease, particularly as a disease of aging, can help critically refine management of this acute and chronic disease, as well as foster preventive strategies to reduce the incidence of this common malady.
基金Acknowledgements The authors would like to thank the reviewers for their detailed reviews and constructive comments, which have helped improve the quality of this paper. This work was supported by the National Natural Science Foundation of China under Crant No. 60873231, the Natural Science Foundation of Jiangsu Province under Grant No. BK2009426, Major State Basic Research Development Program of China under Cwant No.2011CB302903 and Key University Science Research Project of Jiangsu Province under Crant No. 11KJA520002.
文摘The m ajor advantages of EBS-based key rrkanagerrent scheme are its enhanced network survivability, high dynamic performance, and better support for network expansion. But it suffers from the collusion problem, which means it is prone to the cooperative attack of evicted members. A novel EBS-based collusion resistant group management scheme utilizing the construction of Ciphertext-Policy Attribute-Based Encryption （CP-ABE） is proposed. The new scheme satisfies the desired security properties, such as forward secrecy, backward secrecy and collusion secrecy. Compared with existing EBS-based key rmnagement scheme, the new scheme can resolve EBS collusion problem completely. Even all evicted members work together, and share their individual piece of information, they could not access to the new group key. In addition, our scheme is more efficient in terms of conmnication and computation overhead when the group size is large. It can be well controlled even in the case of large-scale application scenarios.
文摘This work collects the characteristics of the family kits of students from the careers related to health in the Espoch, by identifying their knowledge and habits to determine the relationship between self-medication and the possession of medicines contained in the first-aid kit. This is related to the most outstanding frequency （48.1% bedroom） with the use of medicines in the home （48.5% when the treatment ends）. Taking into account that 63.6% do not have a kit, they stored them in inadequate places to control their stability and quality for the use they were made, being analgesics and antibiotics those commonly found during the inspection that took place in the home. This determines that storage habits are not adequate for the proper storage of medications, including having knowledge of health and the importance of proper use by students, being essential to know that medicines must be stored in fresh places and dry, to avoid damage and problems associated with its stability.
文摘Sustainable development is the basis of survival. The SMEs as an important part of our national economy, plays the role of increasing national income, expanding employment, stabilizing social situation. Under the new situation, it needs to change the status quo of financial management, financial management to achieve sustainable development of SMEs. This paper is combined with the financial management of the significance of sustainable development as well as financial management problems in the SME financial management strategy.
