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应用现代生物技术和设备测定和评估肝脏的心肌保护作用
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作者 刘树谦 《中国医疗设备》 2013年第4期1-6,共6页
冠状动脉病变引起的心肌缺血可导致心肌细胞损伤和心功能衰退,但另一方面可激活心肌保护机制,抑制心肌死亡,改进心肌功能。哺乳动物有心源性和非心源性两种心肌保护机制。心源性机制包括心肌内保护分子释放及心肌干细胞激活。心肌保护... 冠状动脉病变引起的心肌缺血可导致心肌细胞损伤和心功能衰退,但另一方面可激活心肌保护机制,抑制心肌死亡,改进心肌功能。哺乳动物有心源性和非心源性两种心肌保护机制。心源性机制包括心肌内保护分子释放及心肌干细胞激活。心肌保护分子可抑制心肌细胞死亡,而心肌干细胞可分化成心肌细胞,进而促进损伤心肌修复。非心源性心肌保护机制主要涉及系统器官和组织。骨髓和肝脏是目前发现的主要心肌保护器官。随着心肌缺血,骨髓可释放造血干细胞和血管内皮前体细胞于血液循环系统。这些细胞可以进入缺血性心肌,促进心肌修复。与此同时,肝脏可表达和释放心肌保护因子,并且能游离肝细胞于血液循环系统。肝脏释放的保护因子可作用于缺血心肌,减少心肌损伤。部分游离肝细胞可随血流进入缺血心肌。这些细胞可能在心肌局部释放保护因子,提升心肌保护因子的水平,因而达到迅速保护心肌的目的。在该项研究中,我们采用了两种主要生物技术和设备,包括cDNA microarray analysis和flowcytometry,来测定和评估肝脏对缺血心肌的保护作用。cDNA microarray analysis用于研发肝脏的心肌防护蛋白,而flow cytometry用于发现心肌缺血时循环的肝细胞。这些生物技术和设备在发现肝脏对缺血心肌的保护上起了至关重要的作用。这里,作者将主要讨论应用现代生物技术和设备对肝脏的心肌保护作用的测定和评估。 展开更多
关键词 生物技术设备 心肌缺血 肝脏 心肌保护
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符合GMP的填充及包装方法——生物技术中高清洁度的液体填充技术
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《化工流程》 2002年第05M期83-83,共1页
关键词 GMP 生物技术设备 液体填充技术 包装设备 包装方法 药品
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厘定生物技术产业
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作者 栗冬 《国外科技动态》 2003年第7期6-7,共2页
关键词 生物技术产业 发展环境 传统型企业 生物技术设备供应企业 技术平台型
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Ergonomic Aspects of Operation of IT Systems in Precision Agriculture
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作者 T. Juliszewski M. Walczykova 《Journal of Environmental Science and Engineering》 2011年第12期1662-1667,共6页
The operation of IT systems is a sine qua non condition in precision agriculture. In the traditional approach, professional competencies of a farmer comprise the ability to operate machines and technical equipment in ... The operation of IT systems is a sine qua non condition in precision agriculture. In the traditional approach, professional competencies of a farmer comprise the ability to operate machines and technical equipment in production technologies for biological raw materials. Precision agriculture increases this range of professional competencies with the ability to use computer IT systems that are complex and, by their very nature, much differing in their content and scope from typical farming knowledge. The ergonomic problem can be brought down to determination whether the operation of IT systems in precision agriculture is adjusted to the predispositions, needs and skills of the farmers. Generally, in the IT system of precision agriculture, three phases can be differentiated: data collection, processing and application. To what extent should they be operated by the farmer, and to what extent by the IT specialist, is the problem that determines effective functioning of precision farming. The ergonomic assessment of some software for equipment operation, generation of harvesting maps and applications points to: (1) the need for standardisation in construction and operation of IT systems; (2) the division of the function-farmer and IT specialist (e.g. from an agriculture consulting institution) in the precision agriculture system. 展开更多
关键词 Operating specialist hardware and software ergonomic assessment need for standardisation.
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