菝葜来源于百合科植物菝葜(Smilax China L.)的干燥根茎,含有丰富的甾体皂苷、黄酮、苯丙烷类和芪类等成分,以利湿去浊、祛风除痹,解毒散瘀的功效为人所知。菝葜具有较好的抗炎、调节糖脂代谢、抗氧化等生物活性,具有很高的药用价值。...菝葜来源于百合科植物菝葜(Smilax China L.)的干燥根茎,含有丰富的甾体皂苷、黄酮、苯丙烷类和芪类等成分,以利湿去浊、祛风除痹,解毒散瘀的功效为人所知。菝葜具有较好的抗炎、调节糖脂代谢、抗氧化等生物活性,具有很高的药用价值。本文通过查阅近年来相关文献,对菝葜的化学成分及药理作用进行了系统的阐述,为菝葜在药品开发和利用中提供了充足的理论依据,以期进一步推动中药菝葜产业的健康、稳定、可持续发展。展开更多
Aim The several species of the genus Paris called ＂Chonglou＂ are famous traditional Chinese herbal medicines. We established the quantitative analysis method of the steroidal saponins in some species of the genus Pa...Aim The several species of the genus Paris called ＂Chonglou＂ are famous traditional Chinese herbal medicines. We established the quantitative analysis method of the steroidal saponins in some species of the genus Paris and discussed their relations. Methods We detected the contents of 11 steroidal saponins in Paris samples with a Kromasel C18 （ 150 mm× 4.6 mm ID, 5μm） column which was subjected to gradient elution with acetonitrile-water （30：70- 60：40, V/V） at a flow rate of 1 mL· min^-1 by HPLC-ELSD and established chemical cluster tree using SPSS 11 software. Results All the samples could be separated and calibration curves of 11 saponins were prepared. We successfully detected the contents of 11 steroidal saponins in 14 Paris spp. in 30 min. The recovery for the assay of saponins was between 95 % and 97 %. The RSD of precision of 11 saponins and stability of samples were below 3 %. Chemical phylogenetic tree based on saponin contents indicated that 17 samples of Paris spp. clustered separately. Conclusion The established method is accurate and convenient, and suitable for the quantitative analysis of these 11 steroidal saponins in Paris spp.. The chemical phylogenetic tree is in accordance with Takhtajian classical taxonomy.展开更多
文摘菝葜来源于百合科植物菝葜(Smilax China L.)的干燥根茎,含有丰富的甾体皂苷、黄酮、苯丙烷类和芪类等成分,以利湿去浊、祛风除痹,解毒散瘀的功效为人所知。菝葜具有较好的抗炎、调节糖脂代谢、抗氧化等生物活性,具有很高的药用价值。本文通过查阅近年来相关文献,对菝葜的化学成分及药理作用进行了系统的阐述,为菝葜在药品开发和利用中提供了充足的理论依据,以期进一步推动中药菝葜产业的健康、稳定、可持续发展。
文摘Aim The several species of the genus Paris called ＂Chonglou＂ are famous traditional Chinese herbal medicines. We established the quantitative analysis method of the steroidal saponins in some species of the genus Paris and discussed their relations. Methods We detected the contents of 11 steroidal saponins in Paris samples with a Kromasel C18 （ 150 mm× 4.6 mm ID, 5μm） column which was subjected to gradient elution with acetonitrile-water （30：70- 60：40, V/V） at a flow rate of 1 mL· min^-1 by HPLC-ELSD and established chemical cluster tree using SPSS 11 software. Results All the samples could be separated and calibration curves of 11 saponins were prepared. We successfully detected the contents of 11 steroidal saponins in 14 Paris spp. in 30 min. The recovery for the assay of saponins was between 95 % and 97 %. The RSD of precision of 11 saponins and stability of samples were below 3 %. Chemical phylogenetic tree based on saponin contents indicated that 17 samples of Paris spp. clustered separately. Conclusion The established method is accurate and convenient, and suitable for the quantitative analysis of these 11 steroidal saponins in Paris spp.. The chemical phylogenetic tree is in accordance with Takhtajian classical taxonomy.
