乙型肝炎病毒（hepatitis B virus，HBV）属于嗜肝病毒家族，嗜肝病毒基因组非常小．使得病毒优化其基风组构造，基冈组的结构是病毒复制策略的直接反映。HBV基因组以两种不同的形式存在．在病毒体内，基因组为部分双链的松弛的环状DNA...乙型肝炎病毒（hepatitis B virus，HBV）属于嗜肝病毒家族，嗜肝病毒基因组非常小．使得病毒优化其基风组构造，基冈组的结构是病毒复制策略的直接反映。HBV基因组以两种不同的形式存在．在病毒体内，基因组为部分双链的松弛的环状DNA分子（relaxed circular DNA．RC-DNA），一条链为完整的L或负链，另一链为S或正链，是不完整的，约为L链的2／3，展开更多
Dicistroviruses comprise a newly characterized and rapidly expanding family of small RNA viruses of invertebrates. Several features of this virus group have attracted considerable research interest in recent years. In...Dicistroviruses comprise a newly characterized and rapidly expanding family of small RNA viruses of invertebrates. Several features of this virus group have attracted considerable research interest in recent years. In this review I provide an overview of the Dicistroviridae and describe progress made toward the understanding and practical application of dicistroviruses, including (i) construction of the first infectious clone of a dicistrovirus, (ii) use of the baculovirus expression system for production of an infectious dicistrovirus, (iii) the use of Drosophila C virus for analysis of host response to virus infection, and (iv) correlation of the presence of Israeli acute paralysis virus with honey bee colony collapse disorder. The potential use of dicistroviruses for insect pest management is also discussed. The structure, mechanism and practical use of the internal ribosome entry site (IRES) elements has recently been reviewed elsewhere.展开更多
文摘乙型肝炎病毒（hepatitis B virus，HBV）属于嗜肝病毒家族，嗜肝病毒基因组非常小．使得病毒优化其基风组构造，基冈组的结构是病毒复制策略的直接反映。HBV基因组以两种不同的形式存在．在病毒体内，基因组为部分双链的松弛的环状DNA分子（relaxed circular DNA．RC-DNA），一条链为完整的L或负链，另一链为S或正链，是不完整的，约为L链的2／3，
基金This journal paper of the Iowa Agriculture and Home Economics Experiment Station, Ames, Iowa,Project No. 6673, was supported by the Iowa State University Plant Sciences Institute, and the Consortium for Plant Biotechnology Research
文摘Dicistroviruses comprise a newly characterized and rapidly expanding family of small RNA viruses of invertebrates. Several features of this virus group have attracted considerable research interest in recent years. In this review I provide an overview of the Dicistroviridae and describe progress made toward the understanding and practical application of dicistroviruses, including (i) construction of the first infectious clone of a dicistrovirus, (ii) use of the baculovirus expression system for production of an infectious dicistrovirus, (iii) the use of Drosophila C virus for analysis of host response to virus infection, and (iv) correlation of the presence of Israeli acute paralysis virus with honey bee colony collapse disorder. The potential use of dicistroviruses for insect pest management is also discussed. The structure, mechanism and practical use of the internal ribosome entry site (IRES) elements has recently been reviewed elsewhere.
