Primary mammary tuberculosis is a rare entity that usually occurs in female of reproductive age. Herein three such patients including two males with ages over 80 years, who underwent surgical resection, are reported. ...Primary mammary tuberculosis is a rare entity that usually occurs in female of reproductive age. Herein three such patients including two males with ages over 80 years, who underwent surgical resection, are reported. Fine needle biopsy failed to achieve specific diagnosis before surgical operation. All of their conditions got satisfactory improvement and anti-tuberculosis chemotherapy was administered postoperatively. Previous literature related to the epidemiology, diagnosis and treatment for mammary tuberculosis will be also reviewed. Mammary tuberculosis is usually related to breast feeding women and is extremely rare in aged man. The possible mechanisms resulting in this disease in our three patients, including direct extension, reactivation, or transmitted by staffs or peers of the nursing home, would also be discussed.展开更多
Objective:To investigate the relationship between dynamic contrast-enhanced MRI parameters and tumor angiogenesis in peripheral pulmonary adenocarcinoma.Methods:Thirty-seven patients with pathologic proved pulmonary a...Objective:To investigate the relationship between dynamic contrast-enhanced MRI parameters and tumor angiogenesis in peripheral pulmonary adenocarcinoma.Methods:Thirty-seven patients with pathologic proved pulmonary adenocarcinoma underwent dynamic contrast-enhanced MR Imaging. Microvessel density(MVD) was counted and vascular endothelial growth factor(VEGF) expression was assessed with immunohistochemical method. Dynamic contrast-enhanced MRI-derived parameters, such as peak height(PH), steepest slope(SS), maximum enhancement rate(E max),enhancement rate at 1-6 minutes(E 1-6), were calculated and compared with MVD in pulmonary adenocarcinoma. And the parameters were also compared between VEGF-positive and VEGF-negative pulmonary adenocarcinoma. Results:The microvessel density was 68.31±19.84 in 37 pulmonary adenocarcinoma. The PH, SS, E max, E 1-6 correlated positively with MVD respectively(P<0.001). The strongest relationship was found between SS and MVD(r=0.827,P<0.001). There was a significant difference between MVD of VEGF-positive pulmonary adenocarcinoma (79.47±21.35) and MVD of VEGF-negative pulmonary adenocarcinoma (43.16±17.85)(P<0.001). All the parameters in VEGF-positive pulmonary adenocarcinoma were higher than those in VEGF-negative pulmonary adenocarcinao(P<0.001). Conclusion: Dynamic contrast-enhanced MRI-derived parameters of pulmonary adenocarcinoma correlated positively with MVD. The parameters in VEGF-positive pulmonary adenocarcinoma were higher than those in VEGF-negative pulmonary adenocarcinoma(P<0.001).展开更多
文摘Primary mammary tuberculosis is a rare entity that usually occurs in female of reproductive age. Herein three such patients including two males with ages over 80 years, who underwent surgical resection, are reported. Fine needle biopsy failed to achieve specific diagnosis before surgical operation. All of their conditions got satisfactory improvement and anti-tuberculosis chemotherapy was administered postoperatively. Previous literature related to the epidemiology, diagnosis and treatment for mammary tuberculosis will be also reviewed. Mammary tuberculosis is usually related to breast feeding women and is extremely rare in aged man. The possible mechanisms resulting in this disease in our three patients, including direct extension, reactivation, or transmitted by staffs or peers of the nursing home, would also be discussed.
文摘Objective:To investigate the relationship between dynamic contrast-enhanced MRI parameters and tumor angiogenesis in peripheral pulmonary adenocarcinoma.Methods:Thirty-seven patients with pathologic proved pulmonary adenocarcinoma underwent dynamic contrast-enhanced MR Imaging. Microvessel density(MVD) was counted and vascular endothelial growth factor(VEGF) expression was assessed with immunohistochemical method. Dynamic contrast-enhanced MRI-derived parameters, such as peak height(PH), steepest slope(SS), maximum enhancement rate(E max),enhancement rate at 1-6 minutes(E 1-6), were calculated and compared with MVD in pulmonary adenocarcinoma. And the parameters were also compared between VEGF-positive and VEGF-negative pulmonary adenocarcinoma. Results:The microvessel density was 68.31±19.84 in 37 pulmonary adenocarcinoma. The PH, SS, E max, E 1-6 correlated positively with MVD respectively(P<0.001). The strongest relationship was found between SS and MVD(r=0.827,P<0.001). There was a significant difference between MVD of VEGF-positive pulmonary adenocarcinoma (79.47±21.35) and MVD of VEGF-negative pulmonary adenocarcinoma (43.16±17.85)(P<0.001). All the parameters in VEGF-positive pulmonary adenocarcinoma were higher than those in VEGF-negative pulmonary adenocarcinao(P<0.001). Conclusion: Dynamic contrast-enhanced MRI-derived parameters of pulmonary adenocarcinoma correlated positively with MVD. The parameters in VEGF-positive pulmonary adenocarcinoma were higher than those in VEGF-negative pulmonary adenocarcinoma(P<0.001).
