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保护性(单)肺通气在肺癌麻醉中的应用 被引量:10
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作者 黄壮荣 章海波 +3 位作者 祝曙光 马庆荣 梁葳 陈凯 《广东医学》 CAS 北大核心 2017年第15期2353-2354,2358,共3页
目的探讨保护性(单)肺通气在肺癌麻醉中的应用。方法选取60例肺癌麻醉患者,采用简单随机分组方法分为两组,每组30例,其中一组采用常规通气方法作为常规通气组(CV组),另一组采用保护性通气方法作为保护性通气组(PV组)。分别在气管插管后(... 目的探讨保护性(单)肺通气在肺癌麻醉中的应用。方法选取60例肺癌麻醉患者,采用简单随机分组方法分为两组,每组30例,其中一组采用常规通气方法作为常规通气组(CV组),另一组采用保护性通气方法作为保护性通气组(PV组)。分别在气管插管后(T1)﹑单肺通气90 min(T2)﹑术后24 h(T3)、术后72 h(T4)时对两组患者进行血气分析并检测患者血清白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)的水平。结果两组患者在单肺通气期间动脉血氧分压(PaO_2)及氧合指数(OI)均有所降低,但PV组明显高于CV组,差异有统计学意义(P<0.05);两组患者血清IL-6、IL-8、TNF-α的水平在T2时点明显升高,相同时点PV组血清IL-6、IL-8、TNF-α的水平明显低于CV组,差异有统计学意义(P<0.05)。结论在肺癌麻醉患者中采用保护性肺通气方法能有效提高动脉氧分压,减轻肺部炎症反应,对手术期间患者肺功能有重要的保护作用。 展开更多
关键词 保护性通气 单肺通气 肺癌麻醉 肺功能
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肺癌手术的麻醉处理163例总结 被引量:1
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作者 黄美清 《中国医药指南(学术版)》 2008年第1期73-74,共2页
目的为确保肺癌手术的麻醉安全。方法采用全麻或全麻复合硬外麻,在全麻后插入双腔气管导管术中单肺通气,观察病人SPo2、气道压变化及肺萎陷情况。结果大部分病人术中HR、BP、SPo2稳定,单肺通气良好,并发低氧血症4例,气道压升高2例,其原... 目的为确保肺癌手术的麻醉安全。方法采用全麻或全麻复合硬外麻,在全麻后插入双腔气管导管术中单肺通气,观察病人SPo2、气道压变化及肺萎陷情况。结果大部分病人术中HR、BP、SPo2稳定,单肺通气良好,并发低氧血症4例,气道压升高2例,其原因为支气管痉挛、陈旧性血块阻塞支气管所致。结论全麻复合硬外麻更适合于肺癌合并高血压及心肌缺血的病人,双腔支气管插管术中单肺通气,便于术中吸痰及手术操作,大大提高了肺癌手术麻醉的安全性。 展开更多
关键词 肺癌手术麻醉 双腔气管插管 单肺通气
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双腔支气管插管单肺通气在肺癌手术麻醉中的分析研究 被引量:4
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作者 宋琼 《现代诊断与治疗》 CAS 2013年第16期3728-3729,共2页
选取2012年4月-2013年3月收治的85例进行肺癌手术的患者进行研究,采用双腔支气管插管进行麻醉的方法,观察患者的麻醉效果。显效67例,有效14例,无效4例,有效率为95.3%。对进行肺癌手术的患者采用双腔支气管插的方法进行麻醉,是一... 选取2012年4月-2013年3月收治的85例进行肺癌手术的患者进行研究,采用双腔支气管插管进行麻醉的方法,观察患者的麻醉效果。显效67例,有效14例,无效4例,有效率为95.3%。对进行肺癌手术的患者采用双腔支气管插的方法进行麻醉,是一种效果较好的麻醉方法。 展开更多
关键词 双腔支气管插管 单肺通气 肺癌手术麻醉
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The anesthesia analysis of the conversion video-assisted thoracic surgery to thoracotomy in pulmonary carcinoma
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作者 Lairong Sun Wenmin Xie 《The Chinese-German Journal of Clinical Oncology》 CAS 2011年第10期567-569,共3页
Objective: The aim of this study was to anesthesia analyse the factors of conversing video-assisted thoracic surgery to thoracectomy in pulmonary carcinoma. Methods: Double-lumen tube bronchial catheter intubation a... Objective: The aim of this study was to anesthesia analyse the factors of conversing video-assisted thoracic surgery to thoracectomy in pulmonary carcinoma. Methods: Double-lumen tube bronchial catheter intubation and interstitial positive pressure ventilation (IPPV) were used in all patients with video-assisted thoracic surgery after fast-speed venous induced anesthesia. IPPV, positive expiratory pressure (PEEP) and continuous positive airway pressure (CPAP) in collapse lobes of lung were used in one lung ventilation, and ventilation parameters were adjusted. Results: Two hundred and fifity- two patients double-lumen bronchial tube intubation used by fiberscope was located very well. The level of oxygen saturation of blood (Sp02), end.tidal carbon dioxide pressure (PETCO2) could be maintained normal. 5 cases were forced to converse video-assisted thoracic surgery to thoracotomy because of 2 cases pulmonary adhesion, 2 cases severe pulmonary dysfunction and 1 case abnormal anatomy respectively. Conclusion: Long one lung ventilation such as pulmonary adhesion, severe pulmonary dysfunction and abnormal anatomy should be considered to be relative contraindication. 展开更多
关键词 carcinoma bronchogenic THORACOSCOPY ANESTHESIA one lung ventilation
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EFFECTS OF COMPOUND ACUPUNCTURE AND MEDICINE ANESTHESIA ON TNF AND INF-Γ CONTENTS IN THE PATIENT OF PNEUMONECTOMY
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作者 周红 童稳圃 +2 位作者 朱余明 施伶俐 闵屹华 《World Journal of Acupuncture-Moxibustion》 2006年第4期13-18,共6页
Objective To explore effects of acupuncture on senJm tumor necrosis factor (TNF) and ,γ-inter- feron (INF-γ) contents in the operative patient of lung cancer. Methods In the first stage, electroacupuncture (EA... Objective To explore effects of acupuncture on senJm tumor necrosis factor (TNF) and ,γ-inter- feron (INF-γ) contents in the operative patient of lung cancer. Methods In the first stage, electroacupuncture (EA) stimulation was given to 25 cases of lung cancer before operation, once daily for 3 consecutive days, with continuous EA stimulation during operation; EA was given once each day from the 5^th-7^th days after operation. In the second stage, EA was added from the 8^th- 10^th days after operation in 30 cases, once daily. Serum TNF and INF-γ contents were compared before and after operation. Results Serum TNF content on the 8th day after operation in the first stage study was lower (P〈0.05) and on the 12th day after operation in the second stage study was higher (P〈0.05) in the compound anesthesia group than that in the general anesthesia group; serum INF-γ contents in the compound anesthesia group on the 8^th day after operation in the first stage and on the 12^th day after operation in the second stage were significantly higher than those in the general anesthesia group (P〈0.01, P〈0.05). Conclusion Acupuncture can regulate serum TNF and INF-γ contents in the patient of operation of lung cancer, with dual-directional regulation on immunologic function. 展开更多
关键词 Acupuncture Compound acupuncture and medicine anesthesia Operation of lung cancerTumor necrosis factor Type interferon
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Regulation of Acupuncture on Interferon-γand Tumor Necrosis Factor of Lung Cancer-Operative Cases 被引量:2
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作者 周红 童稳圃 +3 位作者 施伶俐 闵屹华 沈华 韩丑萍(Translator) 《Journal of Acupuncture and Tuina Science》 2006年第4期230-232,共3页
Objective: To investigate tumor necrosis factor (TNF) of lung the regulation of acupuncture on γ-interteron (LNF-γ) and cancer-operative cases. Methods: to determine the INF-γ and TNF contents in the blood se... Objective: To investigate tumor necrosis factor (TNF) of lung the regulation of acupuncture on γ-interteron (LNF-γ) and cancer-operative cases. Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immunoenzymatic method (ELISA); to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups. Results. The pre-operation INF-γ contents of the two groups showed no significant difference (P〉 0.05); the post operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation (P〈 0.05); the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation (P〈 0.05); the pre-operation TNF contents of the two groups showed no significant difference (P〉 0.05) and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation (P〈 0.05). Conclusion:Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients. 展开更多
关键词 Cancer γ-Acupuncture Therapy Combined Acupuncture and Drug Anesthesia Lung interferon Tumor Necrosis Factor (YNF)
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