目的观察后腹腔镜保留肾上腺手术治疗醛固酮腺瘤的临床疗效。方法回顾性分析重庆医科大学附属第二医院泌尿外科2014年5月至2018年2月收治的56例原发性醛固酮增多症患者的临床资料,其中34例患者行保留肾上腺手术(保留肾上腺组),22例患者...目的观察后腹腔镜保留肾上腺手术治疗醛固酮腺瘤的临床疗效。方法回顾性分析重庆医科大学附属第二医院泌尿外科2014年5月至2018年2月收治的56例原发性醛固酮增多症患者的临床资料,其中34例患者行保留肾上腺手术(保留肾上腺组),22例患者行单侧肾上腺全切术(全切组)。结果 56例患者手术均顺利完成;保留肾上腺组和全切组患者的手术时间[(75.5±10.4) min vs (70.0±9.6) min]、术中出血量[(43.0±7.4) mL vs (40.2±5.5) mL]、拔引流管时间[(2.3±0.9) d vs (2.7±1.1) d]、术后住院时间[(5.8±2.1) d vs (6.4±3.3) d]、病灶大小[(16.4±7.7) mm vs (18.8±4.9) mm]比较差异均无统计学意义(P>0.05);术后随访8~12个月,两组患者在降低血钾、降低血醛固酮、改善血压方面比较差异均无统计学意义(P>0.05);与肾上腺切除组比较,保留肾上腺组患者术后激素替代使用的平均剂量小[(12.03±1.65) mg/d vs (13.12±1.45) mg/d],且脱离激素替代所用时长较短[(4.06±1.43)周vs (7.86±1.72)周],差异均有统计学意义(P<0.05);所有患者随访期间均未复发。结论选择性地对醛固酮腺瘤患者行保留肾上腺的手术,疗效及安全性与行单侧肾上腺切除术相当,且其在术后激素替代过程中有明显优势,值得临床推广。展开更多
AIM:To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS:A prospective study was ...AIM:To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS:A prospective study was conducted from July 2003 to July 2004 at 11 tertiary endoscopic centers. Large colon polyps (> 10 mm in diameter) wererandomized to undergo endoscopic polypectomy with submucosal saline-epinephrine injection (epinephrine group) or normal saline injection (saline group). Endoscopic polypectomy was performed by the conventional snare method,and early (< 12 h) and late bleeding complications (12 h-30 d) were observed. RESULTS:A total of 561 polyps in 486 patients were resected by endoscopic polypectomy. Overall,bleeding complications occurred in 7.6% (37/486) of the patients,including 4.9% (12/244) in the epinephrine group,and 10.3% (25/242) in the saline group. Early and late postpolypectomy bleeding (PPB) occurred in 6.6% (32/486) and 1% (5/486) of the patients,respectively,including 4.5% (11/244),0.4% (1/244) in the epinephrine group,and 8.7% (21/242),1.7% (4/242) in the saline group. No significant differences in the rates of overall,early and late PPB were observed between the 2 groups. Multivariate stepwise logistic regression analysis revealed that large size (> 2 cm) and neoplastic polyps were independently and significantly associated with the presence of PPB. CONCLUSION:The prophylactic submucosal injection of diluted epinephrine does not appear to provide an additional advantage over the saline injection alone for the prevention of PPB.展开更多
The term ＂oncocyte＂ was first used by Hamperl in 1950 to describe a kind of large, highly eosinophilic, granular tumour cell. Oncocytoma refers to the tumour that is composed of oncocytes. Oncocytoma can occur in va...The term ＂oncocyte＂ was first used by Hamperl in 1950 to describe a kind of large, highly eosinophilic, granular tumour cell. Oncocytoma refers to the tumour that is composed of oncocytes. Oncocytoma can occur in various organs throughout the body, commonly salivary glands, thyroid or kidney and less commonly in lung, parathyroid gland, ovary or pituitary gland. Adrenocortical oncocytomas are rare： only 46 cases have been reported worldwide in the literature.2-6 Most of adrenal masses were resected by open operations.3-7 An oncocytoma of the adrenal gland was diagnosed and treated in our hospital recently. Retroperitoneal laparoscopy was performed to remove the mass. We report our recent case and review the literature.展开更多
文摘目的观察后腹腔镜保留肾上腺手术治疗醛固酮腺瘤的临床疗效。方法回顾性分析重庆医科大学附属第二医院泌尿外科2014年5月至2018年2月收治的56例原发性醛固酮增多症患者的临床资料,其中34例患者行保留肾上腺手术(保留肾上腺组),22例患者行单侧肾上腺全切术(全切组)。结果 56例患者手术均顺利完成;保留肾上腺组和全切组患者的手术时间[(75.5±10.4) min vs (70.0±9.6) min]、术中出血量[(43.0±7.4) mL vs (40.2±5.5) mL]、拔引流管时间[(2.3±0.9) d vs (2.7±1.1) d]、术后住院时间[(5.8±2.1) d vs (6.4±3.3) d]、病灶大小[(16.4±7.7) mm vs (18.8±4.9) mm]比较差异均无统计学意义(P>0.05);术后随访8~12个月,两组患者在降低血钾、降低血醛固酮、改善血压方面比较差异均无统计学意义(P>0.05);与肾上腺切除组比较,保留肾上腺组患者术后激素替代使用的平均剂量小[(12.03±1.65) mg/d vs (13.12±1.45) mg/d],且脱离激素替代所用时长较短[(4.06±1.43)周vs (7.86±1.72)周],差异均有统计学意义(P<0.05);所有患者随访期间均未复发。结论选择性地对醛固酮腺瘤患者行保留肾上腺的手术,疗效及安全性与行单侧肾上腺切除术相当,且其在术后激素替代过程中有明显优势,值得临床推广。
基金a grant from the Korean Association for the Study of Intestinal Diseases
文摘AIM:To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS:A prospective study was conducted from July 2003 to July 2004 at 11 tertiary endoscopic centers. Large colon polyps (> 10 mm in diameter) wererandomized to undergo endoscopic polypectomy with submucosal saline-epinephrine injection (epinephrine group) or normal saline injection (saline group). Endoscopic polypectomy was performed by the conventional snare method,and early (< 12 h) and late bleeding complications (12 h-30 d) were observed. RESULTS:A total of 561 polyps in 486 patients were resected by endoscopic polypectomy. Overall,bleeding complications occurred in 7.6% (37/486) of the patients,including 4.9% (12/244) in the epinephrine group,and 10.3% (25/242) in the saline group. Early and late postpolypectomy bleeding (PPB) occurred in 6.6% (32/486) and 1% (5/486) of the patients,respectively,including 4.5% (11/244),0.4% (1/244) in the epinephrine group,and 8.7% (21/242),1.7% (4/242) in the saline group. No significant differences in the rates of overall,early and late PPB were observed between the 2 groups. Multivariate stepwise logistic regression analysis revealed that large size (> 2 cm) and neoplastic polyps were independently and significantly associated with the presence of PPB. CONCLUSION:The prophylactic submucosal injection of diluted epinephrine does not appear to provide an additional advantage over the saline injection alone for the prevention of PPB.
文摘The term ＂oncocyte＂ was first used by Hamperl in 1950 to describe a kind of large, highly eosinophilic, granular tumour cell. Oncocytoma refers to the tumour that is composed of oncocytes. Oncocytoma can occur in various organs throughout the body, commonly salivary glands, thyroid or kidney and less commonly in lung, parathyroid gland, ovary or pituitary gland. Adrenocortical oncocytomas are rare： only 46 cases have been reported worldwide in the literature.2-6 Most of adrenal masses were resected by open operations.3-7 An oncocytoma of the adrenal gland was diagnosed and treated in our hospital recently. Retroperitoneal laparoscopy was performed to remove the mass. We report our recent case and review the literature.
