目的比较单孔腹腔镜根治性肾切除术(LESS-RN)与传统腹腔镜根治性肾切除术(CL-RN)后至少10年的局限性肾癌患者肿瘤疗效和肾功能结局。方法选取2009-2012年在海军军医大学(第二军医大学)第一附属医院接受LESS-RN或CL-RN治疗的T1a~T2a期局...目的比较单孔腹腔镜根治性肾切除术(LESS-RN)与传统腹腔镜根治性肾切除术(CL-RN)后至少10年的局限性肾癌患者肿瘤疗效和肾功能结局。方法选取2009-2012年在海军军医大学(第二军医大学)第一附属医院接受LESS-RN或CL-RN治疗的T1a~T2a期局限性肾癌患者,按患者年龄、BMI、肿瘤大小进行倾向评分匹配,共纳入31对患者,分析患者的基线特征、手术数据、病理结果和随访信息,以评估LESS-RN和CL-RN的长期预后差异。结果LESS-RN组与CL-RN组患者在手术时间[(179.7±43.0)min vs(172.6±50.9)min,P=0.349]、估计失血量[100(50,200)mL vs 100(50,150)mL,P=0.871]、住院时间[6(5,7)d vs 7(6,9)d,P=0.080]方面差异均无统计学意义。LESS-RN组有1例患者发生术中并发症,没有患者发生术后并发症;CL-RN组有1例患者发生术中并发症,3例患者发生术后并发症。LESS-RN组随访时间为(138.0±9.0)个月,CL-RN组为(137.8±9.8)个月(P=0.730)。LESS-RN组与CL-RN组患者总生存率(80.6%vs 74.2%,P=0.181)、肿瘤特异性生存率(93.6%vs 96.8%,P=0.554)、血肌酐变化水平[32(17,45)μmol/L vs 20(5,47)μmol/L,P=0.098]和估算的肾小球滤过率[(60.2±20.9)mL·min^(-1)·(1.73 m^(2))^(-1) vs(66.7±27.8)mL·min^(-1)·(1.73 m^(2))^(-1),P=0.342]差异均无统计学意义。结论LESS-RN是一种安全、可行的治疗局限性肾癌的手术方法,其长期肿瘤疗效和肾功能结局与CL-RN相当。展开更多
目的探讨超声引导下椎旁阻滞对机器人辅助腹腔镜肾切除术患者术后肺功能的影响。方法选择择期行机器人辅助腹腔镜肾切除术患者80例,男40例,女40例,年龄30~70岁,BMI 18.5~35.0 kg/m^(2),ASAⅠ或Ⅱ级。根据随机数字表法将患者分为两组:椎...目的探讨超声引导下椎旁阻滞对机器人辅助腹腔镜肾切除术患者术后肺功能的影响。方法选择择期行机器人辅助腹腔镜肾切除术患者80例,男40例,女40例,年龄30~70岁,BMI 18.5~35.0 kg/m^(2),ASAⅠ或Ⅱ级。根据随机数字表法将患者分为两组:椎旁阻滞联合全麻组(PG组)和单纯全麻组(SG组),每组40例。两组术后均使用羟考酮静脉镇痛。记录术前1 d、术后1~5 d的用力肺活量(FVC)、第1秒用力呼气容量(FEV_(1))、最大呼气中期流量(MMEF)和SpO_(2)。记录术后1~5 d静息和活动(咳嗽)时VAS疼痛评分。记录丙泊酚用量、瑞芬太尼用量,镇痛泵有效按压次数、总按压次数和补救镇痛例数。记录术后首次下床活动时间、术后首次肛门排气时间、术后住院时间和不良反应的发生情况。记录术后5 d肺部并发症和术后30 d再次住院的发生情况。结果与术前1 d比较,术后1~5 d两组FVC、FEV_(1)及MMEF均明显降低(P<0.05),PG组术后1~4 d、SG组术后1~5 d SpO_(2)明显降低(P<0.05)。与SG组比较,PG组术后1~3 d FVC、术后1~5 d FEV_(1)和术后1~4 d MMEF、术后1~3 d SpO_(2)明显升高(P<0.05),术后1~2 d静息和活动时VAS疼痛评分明显降低(P<0.05),丙泊酚和瑞芬太尼用量、镇痛泵有效按压次数、总按压次数及补救镇痛率明显减少(P<0.05),术后首次下床活动时间、术后首次肛门排气时间和术后住院时间明显缩短(P<0.05),术后不良反应发生率和术后5 d的肺部并发症发生率明显降低(P<0.05)。结论超声引导下椎旁阻滞可为机器人辅助腹腔镜肾切除术患者提供更好的术后早期镇痛,改善术后肺功能,降低肺部并发症发生率。展开更多
病史摘要:继发于部分肾切除术的肺栓塞是极少见的术后并发症,本病例报道一例61岁的女性患者,既往有下肢深静脉血栓病史,入院诊断“右肾占位10天”。症状体征:在“后腹腔镜右肾部分切除术”术后3天突发胸闷、气短、大汗、乏力,心前区略...病史摘要:继发于部分肾切除术的肺栓塞是极少见的术后并发症,本病例报道一例61岁的女性患者,既往有下肢深静脉血栓病史,入院诊断“右肾占位10天”。症状体征:在“后腹腔镜右肾部分切除术”术后3天突发胸闷、气短、大汗、乏力,心前区略感疼痛,该患者围术期肺栓塞风险高危。诊断方法:CT肺动脉血管成像示双肺段及段以下层面肺动脉多发栓塞。双下肢血管超声示双侧小腿肌静脉内径增宽伴血栓形成(完全填充型)。治疗方法:予抗凝治疗。临床转归:这是1例术前存在下肢深静脉血栓,于部分肾切除术后出现了肺栓塞的病例,予抗凝治疗,患者预后良好。Case Summary: Pulmonary embolism secondary to partial nephrectomy is an extremely rare postoperative complication. This case report describes a 61-year-old female patient with a history of deep vein thrombosis (DVT) in the lower extremities, who was admitted with a diagnosis of “right renal mass for 10 days.” Symptoms and Signs: On the third day following “retroperitoneal laparoscopic partial nephrectomy of the right kidney,” the patient suddenly developed chest tightness, shortness of breath, profuse sweating, and fatigue, with slight pain in the precordial area. This patient was identified as high-risk for perioperative pulmonary embolism. Diagnostic Methods: CT pulmonary angiography revealed multiple emboli in the segmental and subsegmental branches of the pulmonary arteries in both lungs. Bilateral lower extremity vascular ultrasound indicated widened diameters of the calf muscle veins with complete thrombus formation. Treatment Methods: Anticoagulant therapy was administered. Clinical Outcome: This case involves a patient with pre-existing lower extremity deep vein thrombosis who developed a pulmonary embolism following partial nephrectomy. The patient was treated with anticoagulant therapy and had a favorable prognosis.展开更多
文摘目的比较单孔腹腔镜根治性肾切除术(LESS-RN)与传统腹腔镜根治性肾切除术(CL-RN)后至少10年的局限性肾癌患者肿瘤疗效和肾功能结局。方法选取2009-2012年在海军军医大学(第二军医大学)第一附属医院接受LESS-RN或CL-RN治疗的T1a~T2a期局限性肾癌患者,按患者年龄、BMI、肿瘤大小进行倾向评分匹配,共纳入31对患者,分析患者的基线特征、手术数据、病理结果和随访信息,以评估LESS-RN和CL-RN的长期预后差异。结果LESS-RN组与CL-RN组患者在手术时间[(179.7±43.0)min vs(172.6±50.9)min,P=0.349]、估计失血量[100(50,200)mL vs 100(50,150)mL,P=0.871]、住院时间[6(5,7)d vs 7(6,9)d,P=0.080]方面差异均无统计学意义。LESS-RN组有1例患者发生术中并发症,没有患者发生术后并发症;CL-RN组有1例患者发生术中并发症,3例患者发生术后并发症。LESS-RN组随访时间为(138.0±9.0)个月,CL-RN组为(137.8±9.8)个月(P=0.730)。LESS-RN组与CL-RN组患者总生存率(80.6%vs 74.2%,P=0.181)、肿瘤特异性生存率(93.6%vs 96.8%,P=0.554)、血肌酐变化水平[32(17,45)μmol/L vs 20(5,47)μmol/L,P=0.098]和估算的肾小球滤过率[(60.2±20.9)mL·min^(-1)·(1.73 m^(2))^(-1) vs(66.7±27.8)mL·min^(-1)·(1.73 m^(2))^(-1),P=0.342]差异均无统计学意义。结论LESS-RN是一种安全、可行的治疗局限性肾癌的手术方法,其长期肿瘤疗效和肾功能结局与CL-RN相当。
文摘目的探讨超声引导下椎旁阻滞对机器人辅助腹腔镜肾切除术患者术后肺功能的影响。方法选择择期行机器人辅助腹腔镜肾切除术患者80例,男40例,女40例,年龄30~70岁,BMI 18.5~35.0 kg/m^(2),ASAⅠ或Ⅱ级。根据随机数字表法将患者分为两组:椎旁阻滞联合全麻组(PG组)和单纯全麻组(SG组),每组40例。两组术后均使用羟考酮静脉镇痛。记录术前1 d、术后1~5 d的用力肺活量(FVC)、第1秒用力呼气容量(FEV_(1))、最大呼气中期流量(MMEF)和SpO_(2)。记录术后1~5 d静息和活动(咳嗽)时VAS疼痛评分。记录丙泊酚用量、瑞芬太尼用量,镇痛泵有效按压次数、总按压次数和补救镇痛例数。记录术后首次下床活动时间、术后首次肛门排气时间、术后住院时间和不良反应的发生情况。记录术后5 d肺部并发症和术后30 d再次住院的发生情况。结果与术前1 d比较,术后1~5 d两组FVC、FEV_(1)及MMEF均明显降低(P<0.05),PG组术后1~4 d、SG组术后1~5 d SpO_(2)明显降低(P<0.05)。与SG组比较,PG组术后1~3 d FVC、术后1~5 d FEV_(1)和术后1~4 d MMEF、术后1~3 d SpO_(2)明显升高(P<0.05),术后1~2 d静息和活动时VAS疼痛评分明显降低(P<0.05),丙泊酚和瑞芬太尼用量、镇痛泵有效按压次数、总按压次数及补救镇痛率明显减少(P<0.05),术后首次下床活动时间、术后首次肛门排气时间和术后住院时间明显缩短(P<0.05),术后不良反应发生率和术后5 d的肺部并发症发生率明显降低(P<0.05)。结论超声引导下椎旁阻滞可为机器人辅助腹腔镜肾切除术患者提供更好的术后早期镇痛,改善术后肺功能,降低肺部并发症发生率。
文摘病史摘要:继发于部分肾切除术的肺栓塞是极少见的术后并发症,本病例报道一例61岁的女性患者,既往有下肢深静脉血栓病史,入院诊断“右肾占位10天”。症状体征:在“后腹腔镜右肾部分切除术”术后3天突发胸闷、气短、大汗、乏力,心前区略感疼痛,该患者围术期肺栓塞风险高危。诊断方法:CT肺动脉血管成像示双肺段及段以下层面肺动脉多发栓塞。双下肢血管超声示双侧小腿肌静脉内径增宽伴血栓形成(完全填充型)。治疗方法:予抗凝治疗。临床转归:这是1例术前存在下肢深静脉血栓,于部分肾切除术后出现了肺栓塞的病例,予抗凝治疗,患者预后良好。Case Summary: Pulmonary embolism secondary to partial nephrectomy is an extremely rare postoperative complication. This case report describes a 61-year-old female patient with a history of deep vein thrombosis (DVT) in the lower extremities, who was admitted with a diagnosis of “right renal mass for 10 days.” Symptoms and Signs: On the third day following “retroperitoneal laparoscopic partial nephrectomy of the right kidney,” the patient suddenly developed chest tightness, shortness of breath, profuse sweating, and fatigue, with slight pain in the precordial area. This patient was identified as high-risk for perioperative pulmonary embolism. Diagnostic Methods: CT pulmonary angiography revealed multiple emboli in the segmental and subsegmental branches of the pulmonary arteries in both lungs. Bilateral lower extremity vascular ultrasound indicated widened diameters of the calf muscle veins with complete thrombus formation. Treatment Methods: Anticoagulant therapy was administered. Clinical Outcome: This case involves a patient with pre-existing lower extremity deep vein thrombosis who developed a pulmonary embolism following partial nephrectomy. The patient was treated with anticoagulant therapy and had a favorable prognosis.
