Extrarenal Wilms' tumour(ERWT) is extremely rare with a scant mention in the literature.We described a 7 yearold girl who presented with abdominal pain,vomiting and constipation.Diagnostic investigation and explor...Extrarenal Wilms' tumour(ERWT) is extremely rare with a scant mention in the literature.We described a 7 yearold girl who presented with abdominal pain,vomiting and constipation.Diagnostic investigation and exploratory laparotomy provided evidence of a huge retroperitoneal mass in the lumbosacral area with normal kidneys.Histology and immunophenotyping confirmed the diagnosis of Wilms' tumour.Bone marrow revealed infiltration with non-hematogenous cells and patient was started on chemoradiotherapy.Presently patient is on our follow up and asymptomatic for her disease.展开更多
Wilms' tumor is extremely rare.In this article,we reported one case diagnosed by fine needle aspiration cytology(FNAC) and pathology.A three and a half-year-old boy was admitted to hospital with abdominal pain for...Wilms' tumor is extremely rare.In this article,we reported one case diagnosed by fine needle aspiration cytology(FNAC) and pathology.A three and a half-year-old boy was admitted to hospital with abdominal pain for two days.CT scan showed a large mass in the region of the left kidney of the boy.FNAC was performed on the mass,and the cytologic specimen showed malignant cells suggestive of a Wilms' tumor.Histologic examination of the operative specimen after the left nephrectomy also revealed Wilms' tumor.展开更多
Objective:The aim of the study was to report the experience of National Cancer Institute(NCI),Cairo University,Egypt,in managing various benign and malignant renal tumors with nephron sparing surgery(NSS),and to asses...Objective:The aim of the study was to report the experience of National Cancer Institute(NCI),Cairo University,Egypt,in managing various benign and malignant renal tumors with nephron sparing surgery(NSS),and to assess its safety and feasibility.Methods:Reviewing the literature for NSS,and records of patients who underwent NSS in the period from January 2000 to December 2009 at National Cancer Institute,Cairo University regarding the patient and tumor related characteristics,the indication for NSS,operative technique,postoperative complications,full histopathological data,and follow up results.Results:The total number of patients was 17.Mean age at surgery was 30.7 years(range 1.5-65 years).Five patients had bilateral tumors during surgery.The mean tumor size was 4.5 cm(range 1-9 cm).All patients had normal preoperative kidney functions.Seven patients had an absolute indication for NSS,6 patients had a relative indication,and 4 patients had an elective indication.All the 5 patients with bilateral tumors underwent bilateral simultaneous surgery.Cold ischemia was used in 8 patients,1 patient was exposed to warm ischemia,manual compression was used in 2 patients,and no vascular control was applied in 6 patients.Complications were encountered in 2 patients,one of them had urinary leakage which needed reoperation,and the other had subcutaneous hematoma which was treated conservatively.Histopathological analysis revealed Wilm's tumor(8 patients),angiomyolipoma(4 patients),renal cell carcinoma(4 patients),and hydatid cyst(1 patient).All patients had negative surgical margin.For patients with Wilm's tumor,the mean follow up was 21.4 months(range 0-94 months),2 patients had local recurrence,and 1 patient had distant metastasis.For patients with RCC,the mean follow up was 15.3 months(5-33 months),no patients had local recurrence or distant metastasis.All patients had normal kidney functions during postoperative and follow up periods.Conclusion:NSS is a feasible safe procedure that can be done with acceptable complications rate and it provides a good solution for patients with bilateral tumors,early localized renal cell carcinoma,and benign tumors.展开更多
文摘患儿男,1岁6个月.因B超查出左肾肿物1年,血尿1个月于2009年8月入院.患儿生后6个月行B超检查时发现左肾肿物,无明显不适,1个月前发现肉眼血尿.B超示肿物较初查时增大.体检：一般情况可.腹平软,无压痛,左腹部可及5 cm×6 cm肿物,质中等.CT：左肾显著增大,形态不规则,密度不均匀.右肾轮廓清晰,肾盂、肾盏未见明显异常.增强后,左肾实质内可见一实性肿物,呈不均匀强化,边界较清晰,约4.5 cm ×6.0 cm ×6.0 cm,残余左肾实质强化良好,左侧肾盂受压、移位.右肾实质内可见多发结节影,边界较清晰,强化较正常肾实质低.初步考虑：双肾多发实性肿物,肾母细胞瘤病伴肾母细胞瘤.遂行手术,术中于左肾中部可触及肿物5.0cm×4.5 cm×4.0cm,无法单纯切除肿物,故行左肾切除术.
文摘Extrarenal Wilms' tumour(ERWT) is extremely rare with a scant mention in the literature.We described a 7 yearold girl who presented with abdominal pain,vomiting and constipation.Diagnostic investigation and exploratory laparotomy provided evidence of a huge retroperitoneal mass in the lumbosacral area with normal kidneys.Histology and immunophenotyping confirmed the diagnosis of Wilms' tumour.Bone marrow revealed infiltration with non-hematogenous cells and patient was started on chemoradiotherapy.Presently patient is on our follow up and asymptomatic for her disease.
文摘Wilms' tumor is extremely rare.In this article,we reported one case diagnosed by fine needle aspiration cytology(FNAC) and pathology.A three and a half-year-old boy was admitted to hospital with abdominal pain for two days.CT scan showed a large mass in the region of the left kidney of the boy.FNAC was performed on the mass,and the cytologic specimen showed malignant cells suggestive of a Wilms' tumor.Histologic examination of the operative specimen after the left nephrectomy also revealed Wilms' tumor.
文摘Objective:The aim of the study was to report the experience of National Cancer Institute(NCI),Cairo University,Egypt,in managing various benign and malignant renal tumors with nephron sparing surgery(NSS),and to assess its safety and feasibility.Methods:Reviewing the literature for NSS,and records of patients who underwent NSS in the period from January 2000 to December 2009 at National Cancer Institute,Cairo University regarding the patient and tumor related characteristics,the indication for NSS,operative technique,postoperative complications,full histopathological data,and follow up results.Results:The total number of patients was 17.Mean age at surgery was 30.7 years(range 1.5-65 years).Five patients had bilateral tumors during surgery.The mean tumor size was 4.5 cm(range 1-9 cm).All patients had normal preoperative kidney functions.Seven patients had an absolute indication for NSS,6 patients had a relative indication,and 4 patients had an elective indication.All the 5 patients with bilateral tumors underwent bilateral simultaneous surgery.Cold ischemia was used in 8 patients,1 patient was exposed to warm ischemia,manual compression was used in 2 patients,and no vascular control was applied in 6 patients.Complications were encountered in 2 patients,one of them had urinary leakage which needed reoperation,and the other had subcutaneous hematoma which was treated conservatively.Histopathological analysis revealed Wilm's tumor(8 patients),angiomyolipoma(4 patients),renal cell carcinoma(4 patients),and hydatid cyst(1 patient).All patients had negative surgical margin.For patients with Wilm's tumor,the mean follow up was 21.4 months(range 0-94 months),2 patients had local recurrence,and 1 patient had distant metastasis.For patients with RCC,the mean follow up was 15.3 months(5-33 months),no patients had local recurrence or distant metastasis.All patients had normal kidney functions during postoperative and follow up periods.Conclusion:NSS is a feasible safe procedure that can be done with acceptable complications rate and it provides a good solution for patients with bilateral tumors,early localized renal cell carcinoma,and benign tumors.
