The research considered urgent ecological reasons linked to environment such as worn tires, the waste tire rubber＇s powder was collected from the tire cars repair shops （passed from the sieve No 18 μm）, and used t...The research considered urgent ecological reasons linked to environment such as worn tires, the waste tire rubber＇s powder was collected from the tire cars repair shops （passed from the sieve No 18 μm）, and used to improve the asphalt concrete properties. Raw materials used were prepared and tested. Varies of asphalt concrete mixtures were prepared with different ratios of bitumen （5, 5.5, 6, 6.5, 7% % of concrete weight）. The Marshall mix design method was used to determine optimum conditions for bitumen in asphalt concrete with specific weight, stability and flow Test, the optimum amount of bitumen was 6.1% of whole asphalt concrete. The different percentages of waste tire rubber powder （0.0, 0.05, 0.10, 0.15% of bitumen weight） were added in optimum bitumen of asphalt concretes, then specific weight and Marshall test were evaluated. These asphalt-rubber mixtures were found to act quite differently from traditional, unmodified asphalt mixtures. However, these results indicate that improved pavement performance can be achieved with asphalt-rubber binder.展开更多
Abstract： In a test-fixture that the authors were using, steel tabs adhesively bonded to an aluminum panel debonded before the design load on the real test panel was fully applied. Therefore, studying behavior of adh...Abstract： In a test-fixture that the authors were using, steel tabs adhesively bonded to an aluminum panel debonded before the design load on the real test panel was fully applied. Therefore, studying behavior of adhesive joints for joining dissimilar materials was deemed to be necessary. To determine the failure load responsible for debonding of adhesive joints of two dissimilar materials, stress distributions in adhesive joints as obtained by a nonlinear finite element model of the test-fixture were studied under a gradually increasing compression-shear load. It was observed that in-plane stresses were responsible for the debonding of the steel tabs. To achieve a better understanding of adhesive joints of dissimilar materials, finite element models of adhesive lap joints and ADCB （asymmetric double cantilever beam） were studied, under loadings similar to the loading faced by the test-fixture. The analysis was performed using ABAQUS, a commercially available software, and the cohesive zone modeling was used to study the debonding growth.展开更多
This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more re...This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more resembled living tissue than did bovine collagen and were characterized by their cel1ularity and the presence of numerous capillaries. The Vicryl suture implants were quickly absorbed. Picrosirius polarization revealed the synthesis of host collagen by rat fibroblasts which immigrated into the gut suture and human amnion collagen implants. The authors suggest the potential of gut suture as a soft tissue substitute to improve linear skin contour deficits.展开更多
OBJECTIVE:To study the possible roles of Jinlong capsule(JLC) on the proliferation and apoptosis of human pancreatic cancer cells BxPC-3.METHODS:The human pancreatic cancer cells BxPC-3 were treated with JLC at the co...OBJECTIVE:To study the possible roles of Jinlong capsule(JLC) on the proliferation and apoptosis of human pancreatic cancer cells BxPC-3.METHODS:The human pancreatic cancer cells BxPC-3 were treated with JLC at the concentration of 0.05-1.00 mg/mL for 24-120 h.The inhibition rate of JLC on human pancreatic cancer cells BxPC-3 was detected by 3-(4,5-dimethiylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay.Flow cytometry was employed to measure cell apoptosis using Annexin V-FITC/Propidium iodide(AV-FITC/PI) method.Cell cycles were determined by PI staining.The expression of S100 Calcium binding protein A4(S100A4) in cell matrix was measured by enzyme-linked immunosorbent assay(ELISA).The expression levels of apoptosis-related protein such as BCL2/adenovirus E1B 19 kDa interacting protein 3(BNIP3),B-cell lymphoma/leukemia-2(Bcl-2) and Cys-teinylaspartate specific proteinase 3(Caspase-3) were detected byWestern blotting.RESULTS:JLC significantly inhibited the proliferation of human pancreatic cancer cells BxPC-3 in a dose-dependent and time-dependent manner.JLC promoted cell apoptosis and maintained cell cycle in S and G 2 /M phase rather than G 1 /G 0 phase.The expression of S100A4 in the cell matrix was reduced.The expression of cell apoptotic protein BNIP3 was increased while Bcl-2 was decreased.CONCLUSION:JLC can inhibit the proliferation of human pancreatic cancer cells BxPC-3 by stimulating cell apoptosis,arresting the cell cycle at S and G 2 /M phase which blocks the circulation of normal cell cycle and reducing the expression of S100A4 protein.Higher pro-apoptosis protein BNIP3 and lower anti-apoptosis protein Bcl-2 levels were found,which may be related to the apoptotic effects of JLC.展开更多
This paper selected lumbers of Manchurian ash (Fraxinus rnandshurica), Manchurian walnut(Juglans mandshurica) and Spruce (Picea jezoensis var.kornarovii) for manufacturing glulam with water-borne polymeric-isocyanate ...This paper selected lumbers of Manchurian ash (Fraxinus rnandshurica), Manchurian walnut(Juglans mandshurica) and Spruce (Picea jezoensis var.kornarovii) for manufacturing glulam with water-borne polymeric-isocyanate adhesive to determine process variables. The process variables that includespecific pressure, pressing time and adhesive application amount influencing the shear strength of the glulam,were investigated through the orthogonal test. The results indicated that optimum process variables forglulam manufacturing were as follows: Specific pressure of 1.5 MPa for Spruce and 2.0 MPa both forManchurian ash and Manchurian walnut, pressing time of 60 min and adhesive application amount of 250 g/m2.展开更多
文摘The research considered urgent ecological reasons linked to environment such as worn tires, the waste tire rubber＇s powder was collected from the tire cars repair shops （passed from the sieve No 18 μm）, and used to improve the asphalt concrete properties. Raw materials used were prepared and tested. Varies of asphalt concrete mixtures were prepared with different ratios of bitumen （5, 5.5, 6, 6.5, 7% % of concrete weight）. The Marshall mix design method was used to determine optimum conditions for bitumen in asphalt concrete with specific weight, stability and flow Test, the optimum amount of bitumen was 6.1% of whole asphalt concrete. The different percentages of waste tire rubber powder （0.0, 0.05, 0.10, 0.15% of bitumen weight） were added in optimum bitumen of asphalt concretes, then specific weight and Marshall test were evaluated. These asphalt-rubber mixtures were found to act quite differently from traditional, unmodified asphalt mixtures. However, these results indicate that improved pavement performance can be achieved with asphalt-rubber binder.
文摘Abstract： In a test-fixture that the authors were using, steel tabs adhesively bonded to an aluminum panel debonded before the design load on the real test panel was fully applied. Therefore, studying behavior of adhesive joints for joining dissimilar materials was deemed to be necessary. To determine the failure load responsible for debonding of adhesive joints of two dissimilar materials, stress distributions in adhesive joints as obtained by a nonlinear finite element model of the test-fixture were studied under a gradually increasing compression-shear load. It was observed that in-plane stresses were responsible for the debonding of the steel tabs. To achieve a better understanding of adhesive joints of dissimilar materials, finite element models of adhesive lap joints and ADCB （asymmetric double cantilever beam） were studied, under loadings similar to the loading faced by the test-fixture. The analysis was performed using ABAQUS, a commercially available software, and the cohesive zone modeling was used to study the debonding growth.
文摘This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more resembled living tissue than did bovine collagen and were characterized by their cel1ularity and the presence of numerous capillaries. The Vicryl suture implants were quickly absorbed. Picrosirius polarization revealed the synthesis of host collagen by rat fibroblasts which immigrated into the gut suture and human amnion collagen implants. The authors suggest the potential of gut suture as a soft tissue substitute to improve linear skin contour deficits.
文摘OBJECTIVE:To study the possible roles of Jinlong capsule(JLC) on the proliferation and apoptosis of human pancreatic cancer cells BxPC-3.METHODS:The human pancreatic cancer cells BxPC-3 were treated with JLC at the concentration of 0.05-1.00 mg/mL for 24-120 h.The inhibition rate of JLC on human pancreatic cancer cells BxPC-3 was detected by 3-(4,5-dimethiylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay.Flow cytometry was employed to measure cell apoptosis using Annexin V-FITC/Propidium iodide(AV-FITC/PI) method.Cell cycles were determined by PI staining.The expression of S100 Calcium binding protein A4(S100A4) in cell matrix was measured by enzyme-linked immunosorbent assay(ELISA).The expression levels of apoptosis-related protein such as BCL2/adenovirus E1B 19 kDa interacting protein 3(BNIP3),B-cell lymphoma/leukemia-2(Bcl-2) and Cys-teinylaspartate specific proteinase 3(Caspase-3) were detected byWestern blotting.RESULTS:JLC significantly inhibited the proliferation of human pancreatic cancer cells BxPC-3 in a dose-dependent and time-dependent manner.JLC promoted cell apoptosis and maintained cell cycle in S and G 2 /M phase rather than G 1 /G 0 phase.The expression of S100A4 in the cell matrix was reduced.The expression of cell apoptotic protein BNIP3 was increased while Bcl-2 was decreased.CONCLUSION:JLC can inhibit the proliferation of human pancreatic cancer cells BxPC-3 by stimulating cell apoptosis,arresting the cell cycle at S and G 2 /M phase which blocks the circulation of normal cell cycle and reducing the expression of S100A4 protein.Higher pro-apoptosis protein BNIP3 and lower anti-apoptosis protein Bcl-2 levels were found,which may be related to the apoptotic effects of JLC.
文摘This paper selected lumbers of Manchurian ash (Fraxinus rnandshurica), Manchurian walnut(Juglans mandshurica) and Spruce (Picea jezoensis var.kornarovii) for manufacturing glulam with water-borne polymeric-isocyanate adhesive to determine process variables. The process variables that includespecific pressure, pressing time and adhesive application amount influencing the shear strength of the glulam,were investigated through the orthogonal test. The results indicated that optimum process variables forglulam manufacturing were as follows: Specific pressure of 1.5 MPa for Spruce and 2.0 MPa both forManchurian ash and Manchurian walnut, pressing time of 60 min and adhesive application amount of 250 g/m2.
