糖尿病足是糖尿病最严重的慢性并发症之一,具有较高的致残率和致死率,其发病机制十分复杂,与外周神经病变和下肢动脉缺血有关,也与外伤、感染、营养不良和肾功能不全等局部和全身情况有关。针对病因的去除或是改善是糖尿病足创面治疗的...糖尿病足是糖尿病最严重的慢性并发症之一,具有较高的致残率和致死率,其发病机制十分复杂,与外周神经病变和下肢动脉缺血有关,也与外伤、感染、营养不良和肾功能不全等局部和全身情况有关。针对病因的去除或是改善是糖尿病足创面治疗的关键部分,但是采取方法促进糖尿病足创面的愈合以改善糖尿病患者的预后也是当前医学界关注的焦点。以自体植皮为代表的人体自体成分在创面治疗中发挥重要作用。近年来,人体自体成分在糖尿病足创面的应用及研究不断涌现,在促进糖尿病足创面愈合等方面取得了良好的疗效。Diabetic foot is one of the most serious chronic complications of diabetes, with high disability and mortality rates. Its pathogenesis is very complex and is related to peripheral neuropathy and lower extremity arterial ischemia, as well as local and systemic conditions such as trauma, infection, malnutrition and renal insufficiency. Removing or improving the cause is the key part of diabetic foot wound treatment, but taking methods to promote the healing of diabetic foot wounds to improve the prognosis of diabetic patients is also the focus of current medical attention. Human autologous components represented by autologous skin grafts play an important role in wound treatment. In recent years, the application and research of human autologous components in diabetic foot wounds have continued to emerge, and have achieved good therapeutic effects in promoting the healing of diabetic foot wounds.展开更多
目的探讨贮存式自体成分输血对脊柱手术患者的应用效果。方法回顾性分析2017年9月至2019年9月焦作市人民医院收治的106例择期行多节段脊柱手术患者的临床资料,根据血液贮存方式分为对照组(53例)与研究组(53例)。对照组接受贮存式自体全...目的探讨贮存式自体成分输血对脊柱手术患者的应用效果。方法回顾性分析2017年9月至2019年9月焦作市人民医院收治的106例择期行多节段脊柱手术患者的临床资料,根据血液贮存方式分为对照组(53例)与研究组(53例)。对照组接受贮存式自体全血输血,研究组接受贮存式自体成分输血。对比两组回输血量、出血量、尿量;比较两组术前和术后12 h T淋巴细胞亚群(CD3^+、CD4^+、CD4^+/CD8^+)、NK水平;比较两组术前、术后3 d血电解质水平[钠离子(Na^+)、钾离子(K^+)、钙离子(Ca^2+)]。结果两组患者回输血量、出血量、尿量比较,差异无统计学意义(P>0.05);与对照组比较,研究组术后T淋巴细胞亚群及NK水平均较高,差异有统计学意义(P<0.05);术后3 d研究组K^+水平低于对照组,Ca^2+水平高于对照组,差异有统计学意义(P<0.05)。结论贮存式自体成分输血对脊柱手术患者T淋巴细胞亚群、NK水平及电解质水平影响相对较小,对免疫功能影响轻微,可减少机体的应激反应,利于术后康复,值得临床应用。展开更多
This paper presents a superstructure-based formulation for the synthesis of mass-exchange networks (MENs) considering multiple components. The superstructure is simplified by directly using the mass separation agents ...This paper presents a superstructure-based formulation for the synthesis of mass-exchange networks (MENs) considering multiple components. The superstructure is simplified by directly using the mass separation agents (MSA) from their sources, and therefore the automatic synthesis of the multi-component system involved in the MENs can be achieved without choosing a 'key-component' either for the whole process or the mass exchangers. A mathematical model is proposed to carry out the optimization process. The concentrations, flow rates, matches and unit operation displayed in the obtained network constitute the exact representation of the mass exchange process in terms of all species in the system. An example is used to illustrate and demonstrate the application of the proposed method.展开更多
In this article, AHPS (3 - allyloxy- 2 -hydrory- 1 -Propanesulfonate salt) wassynthesized to use in emulsifier-Ne emulsion polymerization of BA/BMa/MMA systemfor high solid content latexes. Storage stability klow beha...In this article, AHPS (3 - allyloxy- 2 -hydrory- 1 -Propanesulfonate salt) wassynthesized to use in emulsifier-Ne emulsion polymerization of BA/BMa/MMA systemfor high solid content latexes. Storage stability klow behavior of the latexes,morphology of the obtained latex particles, dynamic viscoelastic behavior, tensilestrength and water resistance properties of the resulted copolymers were investigated.The experimental results show that with the addition of AHPS, stability of the emulsionis greatly improved that there appears no apparent precipitation dunring thepolymerization and storage at room temperature for 6 months and at -10℃ for fourmonths. Flow of the latexes follows the Bingham body laws, diameter of the latexparticles is about 0.6μn, of which is larger than that of by conventional emulsionpolymerization(0.12μm). In addition, not only water resistance of the copolymersobtained by emulsifier-free emulsion polymerization is greatly improved, but alsotensile strength is obviously enhanced.展开更多
In the past three decades, molecular magnetism has been a rapidly growing interdisciplinary field in chemistry, phys- ics and materials sciences. It covers diverse range of topics including inorganic/organic/hybrid ma...In the past three decades, molecular magnetism has been a rapidly growing interdisciplinary field in chemistry, phys- ics and materials sciences. It covers diverse range of topics including inorganic/organic/hybrid magnetic molecular ma- terials, multifunctional and/or switchable magnetic molecu- lar materials, molecular nanomagnets, nanostructural mo- lecular magnets, molecular spintronics and biomagnetism. Much research on molecular magnetism has been carried out in China both before and after we organized the Interna- tional Conference on Molecule-Based Magnets 2010 （ICMM 2010） in Beijing.展开更多
文摘糖尿病足是糖尿病最严重的慢性并发症之一,具有较高的致残率和致死率,其发病机制十分复杂,与外周神经病变和下肢动脉缺血有关,也与外伤、感染、营养不良和肾功能不全等局部和全身情况有关。针对病因的去除或是改善是糖尿病足创面治疗的关键部分,但是采取方法促进糖尿病足创面的愈合以改善糖尿病患者的预后也是当前医学界关注的焦点。以自体植皮为代表的人体自体成分在创面治疗中发挥重要作用。近年来,人体自体成分在糖尿病足创面的应用及研究不断涌现,在促进糖尿病足创面愈合等方面取得了良好的疗效。Diabetic foot is one of the most serious chronic complications of diabetes, with high disability and mortality rates. Its pathogenesis is very complex and is related to peripheral neuropathy and lower extremity arterial ischemia, as well as local and systemic conditions such as trauma, infection, malnutrition and renal insufficiency. Removing or improving the cause is the key part of diabetic foot wound treatment, but taking methods to promote the healing of diabetic foot wounds to improve the prognosis of diabetic patients is also the focus of current medical attention. Human autologous components represented by autologous skin grafts play an important role in wound treatment. In recent years, the application and research of human autologous components in diabetic foot wounds have continued to emerge, and have achieved good therapeutic effects in promoting the healing of diabetic foot wounds.
文摘目的观察贮存式自体成分输血与异体输血对胃肠恶性肿瘤患者围术期细胞免疫和体液免疫的影响。方法选择择期全麻下行胃肠肿瘤根治手术患者60例,男33例,女27例,年龄53~69岁,体重47~70 kg,ASAⅠ或Ⅱ级。术中出血200~400 ml,Hb<70 g/L时启动输血,将患者随机分为两组,每组30例。贮存式自体成分输血组(P组):术中输血时采用贮存式自体成分输血;异体输血组(A组):输血时采用异体输血。测定入室时、术毕即刻、术后1、3、7 d外周血中T淋巴细胞亚群、NK细胞百分比和IL-2、IL-10、TNF-α、穿孔素(perforin,PF)浓度。结果与入室时比较,术毕即刻至术后7 d A组CD3^+、CD4^+、NK细胞百分比和CD4^+/CD8^+比值明显降低(P<0.05);术后3、7 d A组CD3^+、CD4^+、NK细胞百分比和CD4^+/CD8^+比值明显低于P组(P<0.05);术后1~7 d A组IL-2浓度明显低于,IL-10浓度明显高于P组(P<0.05)。与入室时比较,术毕即刻至术后3 d A组Ig G、Ig A含量明显降低(P<0.05);术毕即刻P组Ig G、Ig A含量明显降低(P<0.05),术后1、3 d恢复至术前水平。结论围术期异体输血可降低肿瘤患者T细胞亚群和NK细胞百分比并延长其恢复时间,也可一过性降低血浆中免疫球蛋白Ig G、Ig A含量,从而影响患者的免疫功能,而贮存式自体成分输血对肿瘤患者术后免疫功能的影响轻微。
文摘目的探讨贮存式自体成分输血对脊柱手术患者的应用效果。方法回顾性分析2017年9月至2019年9月焦作市人民医院收治的106例择期行多节段脊柱手术患者的临床资料,根据血液贮存方式分为对照组(53例)与研究组(53例)。对照组接受贮存式自体全血输血,研究组接受贮存式自体成分输血。对比两组回输血量、出血量、尿量;比较两组术前和术后12 h T淋巴细胞亚群(CD3^+、CD4^+、CD4^+/CD8^+)、NK水平;比较两组术前、术后3 d血电解质水平[钠离子(Na^+)、钾离子(K^+)、钙离子(Ca^2+)]。结果两组患者回输血量、出血量、尿量比较,差异无统计学意义(P>0.05);与对照组比较,研究组术后T淋巴细胞亚群及NK水平均较高,差异有统计学意义(P<0.05);术后3 d研究组K^+水平低于对照组,Ca^2+水平高于对照组,差异有统计学意义(P<0.05)。结论贮存式自体成分输血对脊柱手术患者T淋巴细胞亚群、NK水平及电解质水平影响相对较小,对免疫功能影响轻微,可减少机体的应激反应,利于术后康复,值得临床应用。
基金Supported by the National Natural Science Foundation of China （20976022）
文摘This paper presents a superstructure-based formulation for the synthesis of mass-exchange networks (MENs) considering multiple components. The superstructure is simplified by directly using the mass separation agents (MSA) from their sources, and therefore the automatic synthesis of the multi-component system involved in the MENs can be achieved without choosing a 'key-component' either for the whole process or the mass exchangers. A mathematical model is proposed to carry out the optimization process. The concentrations, flow rates, matches and unit operation displayed in the obtained network constitute the exact representation of the mass exchange process in terms of all species in the system. An example is used to illustrate and demonstrate the application of the proposed method.
文摘In this article, AHPS (3 - allyloxy- 2 -hydrory- 1 -Propanesulfonate salt) wassynthesized to use in emulsifier-Ne emulsion polymerization of BA/BMa/MMA systemfor high solid content latexes. Storage stability klow behavior of the latexes,morphology of the obtained latex particles, dynamic viscoelastic behavior, tensilestrength and water resistance properties of the resulted copolymers were investigated.The experimental results show that with the addition of AHPS, stability of the emulsionis greatly improved that there appears no apparent precipitation dunring thepolymerization and storage at room temperature for 6 months and at -10℃ for fourmonths. Flow of the latexes follows the Bingham body laws, diameter of the latexparticles is about 0.6μn, of which is larger than that of by conventional emulsionpolymerization(0.12μm). In addition, not only water resistance of the copolymersobtained by emulsifier-free emulsion polymerization is greatly improved, but alsotensile strength is obviously enhanced.
文摘In the past three decades, molecular magnetism has been a rapidly growing interdisciplinary field in chemistry, phys- ics and materials sciences. It covers diverse range of topics including inorganic/organic/hybrid magnetic molecular ma- terials, multifunctional and/or switchable magnetic molecu- lar materials, molecular nanomagnets, nanostructural mo- lecular magnets, molecular spintronics and biomagnetism. Much research on molecular magnetism has been carried out in China both before and after we organized the Interna- tional Conference on Molecule-Based Magnets 2010 （ICMM 2010） in Beijing.
