The interaction of O {2 [ α (2 hydroxy 5 sulphophenylazo)benzylidene]hydrazino}benzoic acid(ZCN) with cetyl trimethyl ammonium bromide(CTAB) was studied by UV spectra in pH=5 0 buffered solution. The results showed t...The interaction of O {2 [ α (2 hydroxy 5 sulphophenylazo)benzylidene]hydrazino}benzoic acid(ZCN) with cetyl trimethyl ammonium bromide(CTAB) was studied by UV spectra in pH=5 0 buffered solution. The results showed the complex has maximum absorption at 540 and 570 nm with an apparent molar absorptivity of 2 0×10 4 L/(mol·cm). Three constants were determined: binding constant K =2 3×10 5; degree of dissociation α =0 03 and binding number n (CTAB)∶ n (ZCN)=1∶2 5.展开更多
Objective: To evaluate the clinical effect of PCB (a new anterior cervical instrumental system combining an intradiscal cage with an integrated plate) in treating traumatic cervical intervertebral disc herniation. Met...Objective: To evaluate the clinical effect of PCB (a new anterior cervical instrumental system combining an intradiscal cage with an integrated plate) in treating traumatic cervical intervertebral disc herniation. Methods: Anterior decompression and PCB internal fixation were used in 22 patients with traumatic cervical intervertebral disc herniation. They were followed up from 3 to 16 months and analyzed by symptom and image data. Among them, 16 patients underwent fixation at one level and 6 patients at two levels. Results: This technique did not cause intraoperative complications. After surgery no screw backout or device failure was found. Based on the JOA grade, 20 patients improved clinically and 2 gently because of serious cervical stenosis. The general excellent rate was 90.9 %. Conclusions: PCB internal fixation is stable. Morbidity of donor and acceptor sites is less. No collars are needed after surgery.展开更多
文摘The interaction of O {2 [ α (2 hydroxy 5 sulphophenylazo)benzylidene]hydrazino}benzoic acid(ZCN) with cetyl trimethyl ammonium bromide(CTAB) was studied by UV spectra in pH=5 0 buffered solution. The results showed the complex has maximum absorption at 540 and 570 nm with an apparent molar absorptivity of 2 0×10 4 L/(mol·cm). Three constants were determined: binding constant K =2 3×10 5; degree of dissociation α =0 03 and binding number n (CTAB)∶ n (ZCN)=1∶2 5.
文摘目的：探讨中国药典2010年版盐酸苄丝肼有关物质检查方法的合理性,并对方法作出改进。方法：采用UPLC-MS联用技术对未知杂质进行鉴定,色谱柱为ACQUITY UPLC BEHC18柱（2.1mm×50mm,1.7μm）,流动相为三氟醋酸-甲醇-水（1∶20∶1000）,流速0.5mL·min^-1,采用正离子扫描（ESI^＋）方式,毛细管电压3.0kV,锥孔电压20V,源温120℃,脱溶剂气温度400℃,脱溶剂气流量600L·h^-1,锥孔气流量50L·h^-1。采用改进后的HPLC法检测该杂质,使用Phenomenex Luna C8色谱柱（4.6mm×250mm,5μm）,流动相为A（2.2g庚烷磺酸钠和6.8g磷酸二氢钾溶于900mL水,加入50mL甲醇,用磷酸调至pH3.5）-B（2.2g庚烷磺酸钠和6.8g磷酸二氢钾溶于500mL水,用磷酸调至pH35,加入500mL甲醇）,梯度洗脱（0～15min,0%B→100%B;15～25min,100%B;25～30min,100%B→0%B;30～35min,0%B）,流速1.3mL·min^-1,检测波长210nm,柱温30℃。结果：中国药典2010年版方法不能检出主要杂质三羟苄基苄丝肼,本文建立的HPLC法能够有效检出该杂质。结论：本文方法专属性强,灵敏度高,实验结果准确可靠,可作为测定盐酸苄丝肼有关物质的检查方法,为新版中国药典盐酸苄丝肼有关物质检查方法的完善提供参考。
文摘Objective: To evaluate the clinical effect of PCB (a new anterior cervical instrumental system combining an intradiscal cage with an integrated plate) in treating traumatic cervical intervertebral disc herniation. Methods: Anterior decompression and PCB internal fixation were used in 22 patients with traumatic cervical intervertebral disc herniation. They were followed up from 3 to 16 months and analyzed by symptom and image data. Among them, 16 patients underwent fixation at one level and 6 patients at two levels. Results: This technique did not cause intraoperative complications. After surgery no screw backout or device failure was found. Based on the JOA grade, 20 patients improved clinically and 2 gently because of serious cervical stenosis. The general excellent rate was 90.9 %. Conclusions: PCB internal fixation is stable. Morbidity of donor and acceptor sites is less. No collars are needed after surgery.
