With the aid of a class of nonlinear ordinary differential equation （ODE） and its various positive solutions, four types of exact solutions of the generalized derivative nonlinear Sehrodinger equation （GDNLSE） hav...With the aid of a class of nonlinear ordinary differential equation （ODE） and its various positive solutions, four types of exact solutions of the generalized derivative nonlinear Sehrodinger equation （GDNLSE） have been found out, which are the bell-type solitary wave solution, the algebraic solitary wave solution, the kink-type solitary wave solution and the sinusoidal traveling wave solution, provided that the coefficients of GDNLSE satisfy certain constraint conditions. For more general GDNLSE, the similar results are also given.展开更多
We extend Lou＇s direct perturbation method for solving the nonlinear Schrodinger equation to the case of the derivative nonlinear Schrodinger equation （DNLSE）. By applying this method, different types of perturbati...We extend Lou＇s direct perturbation method for solving the nonlinear Schrodinger equation to the case of the derivative nonlinear Schrodinger equation （DNLSE）. By applying this method, different types of perturbation solutions are obtained. Based on these approximate solutions, the analytical forms of soliton parameters, such as the velocity, the width and the initial position, are carried out and the effects of perturbation on solitons are analyzed at the same time. A numerical simulation of perturbed DNLSE finally verifies the results of the perturbation method.展开更多
In order to improve the safety properties of an offloading system with side-by-side （SBS） mooring in which the FPSO is moored by a yoke system in the field of BZ25-1, it is necessary to analyze those properties. Acc...In order to improve the safety properties of an offloading system with side-by-side （SBS） mooring in which the FPSO is moored by a yoke system in the field of BZ25-1, it is necessary to analyze those properties. According to the experience of similar projects, tow strategies of different offioading arrangements were discussed by using the 3-D radiation/diffraction theory and quasi-static time domain method to assess their respective safety properties. Through the safety assessment analysis of different arrangement comparisons, various ways to improve the safety properties of off＇loading systems with side-by-side mooring were verified by analyzing the tension in the mooring lines and the fender deflection. Through comparison it can be concluded that by enlarging the key factors properly, including the size of the fenders and the hawsers as well as the number of hawsers, a better safety performance can be achieved.展开更多
Objective To investigate the anti-tumor effect of ZM-66 on multidrug-resistant leukemic cell line K562/ADM. Methods The K562/ADM cells were treated with varying concentrations （0, 1, 2, 4×10^-3 mmol/L） of ZM-6...Objective To investigate the anti-tumor effect of ZM-66 on multidrug-resistant leukemic cell line K562/ADM. Methods The K562/ADM cells were treated with varying concentrations （0, 1, 2, 4×10^-3 mmol/L） of ZM-66 or etoposide for 24 hours. The proliferation was detected by Sulforhodamine B Sodium Salt （SRB） assay and apoptosis was detected by flow cytometry analysis and fluorescent staining. In addition, the expression levels of p53 and bax genes in K562/ADM cells were detected by RT-PCR analysis. The level of P-glycoprotein （P-gp）, P53 and Bax protein in K562/ADM cells were detected by Western blot assay. Results SRB assay demonstrated that etoposide had little inhibitory effect on K562/ADM cells, whereas ZM-66 （1, 2, 4×10^-3 mmol/L） had significantly inhibitory effect on K562/ADM cells （all P〈0.01）. The acridine orange/propidium iodide dual staining showed that there were typical condensation of chromatin and nuclear fragmentation nuclei with red color in ZM-66 treated cells. Flow cytometric analysis showed that there was a significantly increase of apoptotic cells i~ K562/KDM cells after treated with ZM-66. RT-PCR showed that the p53 and bax mRNA expression levels in K562/ADM cells treated with ZM-66 at 1, 2, 4×10^-3 mmol/L were higher than those in the cell without treatment. Western blot showed that the P53 and Bax protein expression levels in K562/ADM cells treated with ZM-66 at 2, 4x 10 s mmol/L were higher than those in the cell without treatment. But the P-gp protein expression level in K562/ADM cells treated with ZM-66 at 2, 4×10^-3 mmol/L was gradually lower than those in the cell without treatment. Conclusion ZM-66 is able to induce cell death by apoptosis in vitro, as a result of the reverse of theapoptosis resistance in drug-resistant K562/ADM cells by modulating expression of key factors associated with apoptosis induction.展开更多
基金the Natural Science Foundation of Education Department of Henan Province of China under Grant No.2007110010the Science Foundation of Henan University of Science and Technology under Grant Nos.2006ZY-001 and 2006ZY-011
文摘With the aid of a class of nonlinear ordinary differential equation （ODE） and its various positive solutions, four types of exact solutions of the generalized derivative nonlinear Sehrodinger equation （GDNLSE） have been found out, which are the bell-type solitary wave solution, the algebraic solitary wave solution, the kink-type solitary wave solution and the sinusoidal traveling wave solution, provided that the coefficients of GDNLSE satisfy certain constraint conditions. For more general GDNLSE, the similar results are also given.
基金supported by National Natural Science Foundation of China under Grant No.10575087
文摘We extend Lou＇s direct perturbation method for solving the nonlinear Schrodinger equation to the case of the derivative nonlinear Schrodinger equation （DNLSE）. By applying this method, different types of perturbation solutions are obtained. Based on these approximate solutions, the analytical forms of soliton parameters, such as the velocity, the width and the initial position, are carried out and the effects of perturbation on solitons are analyzed at the same time. A numerical simulation of perturbed DNLSE finally verifies the results of the perturbation method.
基金Supported by the China National 111 project under Grant No.B07019Important National Science & Technology Specific Projects under Grant No.2008ZX05-056-03
文摘In order to improve the safety properties of an offloading system with side-by-side （SBS） mooring in which the FPSO is moored by a yoke system in the field of BZ25-1, it is necessary to analyze those properties. According to the experience of similar projects, tow strategies of different offioading arrangements were discussed by using the 3-D radiation/diffraction theory and quasi-static time domain method to assess their respective safety properties. Through the safety assessment analysis of different arrangement comparisons, various ways to improve the safety properties of off＇loading systems with side-by-side mooring were verified by analyzing the tension in the mooring lines and the fender deflection. Through comparison it can be concluded that by enlarging the key factors properly, including the size of the fenders and the hawsers as well as the number of hawsers, a better safety performance can be achieved.
基金Supported by the Great Program of Science Foundation of Tianjin(08JCYBJC070000)the Program of Science Foundation of Tianjin(06YFJZJCO2700)the National Natural Science Foundation of China(30873363)
文摘Objective To investigate the anti-tumor effect of ZM-66 on multidrug-resistant leukemic cell line K562/ADM. Methods The K562/ADM cells were treated with varying concentrations （0, 1, 2, 4×10^-3 mmol/L） of ZM-66 or etoposide for 24 hours. The proliferation was detected by Sulforhodamine B Sodium Salt （SRB） assay and apoptosis was detected by flow cytometry analysis and fluorescent staining. In addition, the expression levels of p53 and bax genes in K562/ADM cells were detected by RT-PCR analysis. The level of P-glycoprotein （P-gp）, P53 and Bax protein in K562/ADM cells were detected by Western blot assay. Results SRB assay demonstrated that etoposide had little inhibitory effect on K562/ADM cells, whereas ZM-66 （1, 2, 4×10^-3 mmol/L） had significantly inhibitory effect on K562/ADM cells （all P〈0.01）. The acridine orange/propidium iodide dual staining showed that there were typical condensation of chromatin and nuclear fragmentation nuclei with red color in ZM-66 treated cells. Flow cytometric analysis showed that there was a significantly increase of apoptotic cells i~ K562/KDM cells after treated with ZM-66. RT-PCR showed that the p53 and bax mRNA expression levels in K562/ADM cells treated with ZM-66 at 1, 2, 4×10^-3 mmol/L were higher than those in the cell without treatment. Western blot showed that the P53 and Bax protein expression levels in K562/ADM cells treated with ZM-66 at 2, 4x 10 s mmol/L were higher than those in the cell without treatment. But the P-gp protein expression level in K562/ADM cells treated with ZM-66 at 2, 4×10^-3 mmol/L was gradually lower than those in the cell without treatment. Conclusion ZM-66 is able to induce cell death by apoptosis in vitro, as a result of the reverse of theapoptosis resistance in drug-resistant K562/ADM cells by modulating expression of key factors associated with apoptosis induction.
