The vibrating string pressure sensor is designed according to the working surroundings and conditions. this sensor is used for the weighing of the fixed-quantity bucket loader in the main shaft lifting systems of coal...The vibrating string pressure sensor is designed according to the working surroundings and conditions. this sensor is used for the weighing of the fixed-quantity bucket loader in the main shaft lifting systems of coal mines. The design of the sensor has been introduced in detail. Calibrations and errors of the sensor theoretical fornada have also been analyzed.展开更多
The rapid endothelialization of tissue-engineered blood vessels(TEBVs) can effectively prevent thrombosis and inhibit intimal hyperplasia. The traditional Chinese medicine ingredient icariin is highly promising for th...The rapid endothelialization of tissue-engineered blood vessels(TEBVs) can effectively prevent thrombosis and inhibit intimal hyperplasia. The traditional Chinese medicine ingredient icariin is highly promising for the treatment of cardiovascular diseases.β-cyclodextrin sulfate is a type of hollow molecule that has good biocompatibility and anticoagulation properties and exhibits a sustained release of icariin. We studied whether icariin-loaded β-cyclodextrin sulfate can promote the endothelialization of TEBVs. The experimental results showed that icariin could significantly promote the proliferation and migration of endothelial progenitor cells; at the same time, icariin could promote the migration of rat vascular endothelial cells(RAVECs). Subsequently,we used an electrostatic force to modify the surface of the TEBVs with icariin-loaded β-cyclodextrin sulfate, and these vessels were implanted into the rat common carotid artery. After 3 months, micro-CT results showed that the TEBVs modified using icariin-loaded β-cyclodextrin sulfate had a greater patency rate. Scanning electron microscopy(SEM) and CD31 immunofluorescence results showed a better degree of endothelialization. Taken together, icariin-loaded β-cyclodextrin sulfate can achieve anticoagulation and rapid endothelialization of TEBVs to ensure their long-term patency.展开更多
The piston crank mechanism is an important component of a reciprocating piston engine. It is an inherent vibration system, and as such, the calculation of unbalance quantity is a critical procedure in balancing mechan...The piston crank mechanism is an important component of a reciprocating piston engine. It is an inherent vibration system, and as such, the calculation of unbalance quantity is a critical procedure in balancing mechanism design, which is adopted to balance inertia loading. The traditional method usually applies a Taylor series expansion with the crank-conrod ratio, then a Fourier transform with the crank angle. The Taylor expansion generally ignores the influence on calculations resulting from the high order terms. However, the high order terms of the Taylor expansion will also contribute to the low order terms in the Fourier series. This will induce poor precision in the inertia loading calculation, especially in a high crank-conrod ratio engine. Thus, this paper proposes a new closed-form method, which only adopts a Fourier transformation for the calculation. The coefficients of the Fourier transformation terms contain the contributions of all order terms of the crank-conrod ratio. Therefore, we named it as a closed-form method. Compared with the traditional method, the closed-form method improves the numerical accuracy of the secondary reciprocating inertia force by 1.5%–4%, when the crank-conrod ratio varies from 0.25 to 0.4. Using this new closedform method to design a balancing mechanism, the primary and secondary reciprocating inertia forces can be completely balanced. For an engine, where the primary and secondary inertia forces are balanced, the ratio of the residual inertia force to the total inertia force using the traditional method is 1.5%, while the ratio decreases to 0.5% using the closed-form method. The closed-form method is independent of engine configurations, including centric and eccentric engines, and single and multicylinder engines. Examples of applications using the proposed method are provided.展开更多
文摘The vibrating string pressure sensor is designed according to the working surroundings and conditions. this sensor is used for the weighing of the fixed-quantity bucket loader in the main shaft lifting systems of coal mines. The design of the sensor has been introduced in detail. Calibrations and errors of the sensor theoretical fornada have also been analyzed.
基金supported by the National Science Fund for Distinguished Young Scholars (31625011)the National Key Research and Development Program (2016YFC1101100)+1 种基金the National Key Research and Development Plan Young Scientists Program (2017YFA0106000)the Young Elite Scientists Sponsorship Program by Cast (YESS20160180)
文摘The rapid endothelialization of tissue-engineered blood vessels(TEBVs) can effectively prevent thrombosis and inhibit intimal hyperplasia. The traditional Chinese medicine ingredient icariin is highly promising for the treatment of cardiovascular diseases.β-cyclodextrin sulfate is a type of hollow molecule that has good biocompatibility and anticoagulation properties and exhibits a sustained release of icariin. We studied whether icariin-loaded β-cyclodextrin sulfate can promote the endothelialization of TEBVs. The experimental results showed that icariin could significantly promote the proliferation and migration of endothelial progenitor cells; at the same time, icariin could promote the migration of rat vascular endothelial cells(RAVECs). Subsequently,we used an electrostatic force to modify the surface of the TEBVs with icariin-loaded β-cyclodextrin sulfate, and these vessels were implanted into the rat common carotid artery. After 3 months, micro-CT results showed that the TEBVs modified using icariin-loaded β-cyclodextrin sulfate had a greater patency rate. Scanning electron microscopy(SEM) and CD31 immunofluorescence results showed a better degree of endothelialization. Taken together, icariin-loaded β-cyclodextrin sulfate can achieve anticoagulation and rapid endothelialization of TEBVs to ensure their long-term patency.
文摘The piston crank mechanism is an important component of a reciprocating piston engine. It is an inherent vibration system, and as such, the calculation of unbalance quantity is a critical procedure in balancing mechanism design, which is adopted to balance inertia loading. The traditional method usually applies a Taylor series expansion with the crank-conrod ratio, then a Fourier transform with the crank angle. The Taylor expansion generally ignores the influence on calculations resulting from the high order terms. However, the high order terms of the Taylor expansion will also contribute to the low order terms in the Fourier series. This will induce poor precision in the inertia loading calculation, especially in a high crank-conrod ratio engine. Thus, this paper proposes a new closed-form method, which only adopts a Fourier transformation for the calculation. The coefficients of the Fourier transformation terms contain the contributions of all order terms of the crank-conrod ratio. Therefore, we named it as a closed-form method. Compared with the traditional method, the closed-form method improves the numerical accuracy of the secondary reciprocating inertia force by 1.5%–4%, when the crank-conrod ratio varies from 0.25 to 0.4. Using this new closedform method to design a balancing mechanism, the primary and secondary reciprocating inertia forces can be completely balanced. For an engine, where the primary and secondary inertia forces are balanced, the ratio of the residual inertia force to the total inertia force using the traditional method is 1.5%, while the ratio decreases to 0.5% using the closed-form method. The closed-form method is independent of engine configurations, including centric and eccentric engines, and single and multicylinder engines. Examples of applications using the proposed method are provided.
