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质控方案设计工具在室内质量控制中的应用
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作者 邓德耀 李增安 +1 位作者 周林华 支国华 《诊断学理论与实践》 2005年第5期406-409,共4页
目的:应用几种质控方案设计工具,根据我室现有检测方法实际性能设计理性的室内质量控制方法。方法:依据美国 CLIA’88能力验证计划的分析质量要求确定临床总允许误差(TEa),以长期室内质量控制的数据估计各方法的不精密度(CV%),以参加卫... 目的:应用几种质控方案设计工具,根据我室现有检测方法实际性能设计理性的室内质量控制方法。方法:依据美国 CLIA’88能力验证计划的分析质量要求确定临床总允许误差(TEa),以长期室内质量控制的数据估计各方法的不精密度(CV%),以参加卫生部临床检验中心的能力对比检验(PT)成绩估计不准确度(bias%),以此计算临界误差的大小,按照方法的过程能力大小使用质控选择表格进行规则的初期选择,并用功效函数图确认质控方法的性能,确定到达特定水平质量保让时,不同规则及每批测定质控个数需检出的临界误差大小,并建立操作过程规范图。结果:我室总胆红素(TB)、肌酐(CREA)、胆固醇(CHO)的测定在低值水平处方法性能较差,不能很好地检测出误差,需要查找原因进行质量改进,其他项目可根据方法性能选择不同的规则进行控制。结论:通过质控方案设计工具的使用,建立适合本室的方法控制规则,既保证测定结果能够满足临床的质量要求,又达到节约成本的目的,同时通过积极查找并解决不满意方法存在的问题,进行持续质量改进提高我室的过程能力。 展开更多
关键词 室内 方案设计工具
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ISO 15189:2012与室内质量控制 被引量:30
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作者 肖亚玲 王薇 王治国 《临床检验杂志》 CAS CSCD 北大核心 2014年第2期124-125,共2页
室内质量控制(质控)是保证检验质量的重要措施。ISO 15189:2012对室内质控部分内容作了相应的规定。定量检测应规定允许总误差,选择合适的质控材料,根据检测性能设计合理的质控程序,包括质控规则和频率;定性检测每批应包括阴性和阳性质... 室内质量控制(质控)是保证检验质量的重要措施。ISO 15189:2012对室内质控部分内容作了相应的规定。定量检测应规定允许总误差,选择合适的质控材料,根据检测性能设计合理的质控程序,包括质控规则和频率;定性检测每批应包括阴性和阳性质控品,根据质控品阴性、阳性结果判断是否在控。出现失控现象时,应仔细分析误差类型,积极查找失控原因,采取纠正措施,并做详细记录。 展开更多
关键词 ISO15189 室内 质控设计
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Design and Performance of a Controlled Environment Mini-chamber for Measuring Produce Quality Deterioration
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作者 Denyse I. LeBlanc Clement Vigneault +6 位作者 Jereme Boutin Vicky Toussaint Denis Charlebois Charles F.Fomey Gaetan Bourgeois Alain Clement Greg S. Bezanson 《Journal of Agricultural Science and Technology(B)》 2012年第4期391-399,共9页
To minimize losses between harvest and retail display, a system is needed to track temperature and RH exposure of fresh produce and predict its quality at each step of the distribution chain. With accurate models, suc... To minimize losses between harvest and retail display, a system is needed to track temperature and RH exposure of fresh produce and predict its quality at each step of the distribution chain. With accurate models, such system could (1) identify problematic situations before losses occur; (2) become a management tool for decision makers; and (3) help quantify the real impact of individual inappropriate conditions. A project was initiated to develop models required for such a decision system. Because the data required to develop models were not available for most fruit and vegetables, a series of storage trials was planned for measuring changes in physiological and microbial quality, and development of physiological disorders and/or diseases, as a function of time, temperature and RH. To meet this objective, controlled environment mini-chambers were designed, built and instrumented for measuring the effect of traceable environmental conditions encountered during storage and transportation of fresh horticultural produce of similar size and shape as tomato. Detailed design and performance evaluation of these mini-chambers are presented. 展开更多
关键词 Lab scale storage chamber temperature relative humidity fruit and vegetable quality.
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Conceptual Proposal of a Facility Design for Accommodating Minipigs for Pharmaceutical and Radiopharmaceutical Research
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作者 Elizabeth B. F. Lainetti Luiz Augusto C. Passos +1 位作者 Carlos R. J. Soares Nanci do Nascimento 《Journal of Civil Engineering and Architecture》 2016年第8期881-887,共7页
The use of Animal House Facilities of IPEN-CNEN/SP (Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil) has provided rats and mice with controlled sanitary quality for research an... The use of Animal House Facilities of IPEN-CNEN/SP (Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil) has provided rats and mice with controlled sanitary quality for research and quality control in the production of radiopharmaceuticals lots, produced at IPEN, following rules of CONCEA-Brazilian National Council for Animal Experimentation Control and approved in CEUA (Ethics Committee on the Use of Animals), before they are sent to hospitals and clinics spread out in Brazil, for use in nuclear medicine. The production and the supply of high quality laboratory animals have fundamental importance for the accomplishment of vanguard scientific research, with reproducibility and universality. The quality of those animals depends, largely, on the available facilities for their production and lodging, to assure the demanded sanitary control and animal's welfare, in agreement with the ethical principles that control the activity. Therefore, the facilities design is of vital importance so that the mentioned requirements can be reached. Nevertheless, pigs and miniature pigs have gained importance as large animal models in medicine. With their size, organ capacity, and physiology resembling in several aspects that of humans, pigs are well suited for preclinical experiments and long-term safety studies. Minipigs will be used for preclinical testing of radiopharmaceuticals and assays radioactive materials for cardiac tests. This paper describes the premises and preliminary activities that have been performed at IPEN for the design of new Animal House Facilities dedicated to keeping minipigs taking into account fundamental aspects such as: animal's welfare, sanitation, genetic, in agreement with the ethical principles that control the activity and environmental concerns. 展开更多
关键词 Research animals minipigs HOUSING FACILITY design conceptual proposal.
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Study on life-cycle risk management of high earth-rock dam project
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作者 Zhang Nianmu Zhang Zongliang Yan Lei 《Engineering Sciences》 EI 2013年第5期45-50,共6页
Based on advanced computer technology, internet of things (lOT) technology, project management con- cept and professional technology and combined with the innovative theories, methods and techniques in earlier hy- d... Based on advanced computer technology, internet of things (lOT) technology, project management con- cept and professional technology and combined with the innovative theories, methods and techniques in earlier hy- dropower projects, the life-cycle risk management system of high earth-rock dam project for Nuozhadu project was developed. The system mainly includes digital dam, three-dimensional design, construction quality monito- ring, safety assessment and warning, etc, to integrally manage and analyze the dam design, constructional quality and safety monitoring information. It realized the dynamic updates of the comprehensive information and the safe- ty quality monitoring in the project life cycle, and provided the basic platform for the scientific management of the construction and operation safety of high earth-rock dam. Application in Nuozhadu earth-rock dam showed that construction safety monitoring and warning greatly helped accelerate the construction progress and improve project quality, and provided a new way for the quality safety control of high earth-rock dam. 展开更多
关键词 high earth-rock dam Nuozhadu hydropower station LIFE-CYCLE safety construction risk management
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A cross-layer approach to enable multipacket transmission in MIMO-SDMA based WLAN
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作者 Sheng-bo CHEN Wei CHEN +2 位作者 Wei-lan HUANG Li-jun ZHAI Xu-ming LIU 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2009年第2期271-278,共8页
We propose a medium access control(MAC) protocol for uplink transmissions in wireless local area networks(WLANs),where both stations and access points(APs) are equipped with multiple antennas. The protocol solves some... We propose a medium access control(MAC) protocol for uplink transmissions in wireless local area networks(WLANs),where both stations and access points(APs) are equipped with multiple antennas. The protocol solves some common problems in utilizing multiple input multiple output(MIMO) under the 802.11 protocol,e.g.,how to deploy preamble(training sequence) used for channel estimation and how to enable simultaneous data transmissions,and facilitates two simultaneous uplink data transmissions via a cross-layer approach. Furthermore,we develop a 3D discrete-time Markov model to analyze the per-formance of the proposed WLAN scheme. The analytical results are verified by simulation,and numerical results show that the system throughput can be significantly improved by our proposed scheme as compared with conventional schemes. 展开更多
关键词 Multiple input multiple output (MIMO) Medium access control (MAC) Cross-layer design
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