The combined effects of vertical overturning circulation(VOC) zonal length scale and moist static energy(MSE)tendency zonal asymmetry on MJO phase speed were investigated based on diagnosis of ERA-Interim data over a ...The combined effects of vertical overturning circulation(VOC) zonal length scale and moist static energy(MSE)tendency zonal asymmetry on MJO phase speed were investigated based on diagnosis of ERA-Interim data over a 40-year period(1979-2019).In a key region(80°-100°E),128 MJO events were selected.It was found that the larger the VOC zonal length scale,the faster the MJO eastward propagation.The correlation coefficient between them was 0.52,exceeding the 99% confidence level.A significant positive correlation(0.59) was also identified between the phase speed and MSE tendency zonal asymmetry.A linear regression model based on the aforementioned two parameters was constructed,and the phase speed could be estimated based on the model.The correlation coefficient between the reconstructed phase speed and its observed counterpart was 0.73,exceeding the 99% confidence level with an F-test.A composite analysis of the fast and slow groups indicated that the VOC zonal length scale was modulated by the background state.An El Nino(La Ni?a)-like SST pattern and associated precipitation anomalies promoted a larger(smaller) VOC zonal length scale and thus a faster(slower)propagation speed.A sensitivity test with a reference point in a different longitudinal zone(120°-140°E) was conducted.Again,there were significant relationships between the MJO phase speed and the two parameters.The correlation between the reconstructed and observed phase speed was 0.67,exceeding the 99% confidence level.展开更多
This paper, using the method of "the combination of 14 o'clock relative humidity, visibility and weather phenomena", selected haze days during 1980-2012 from 13 stations of Hubei Province, and studied ye...This paper, using the method of "the combination of 14 o'clock relative humidity, visibility and weather phenomena", selected haze days during 1980-2012 from 13 stations of Hubei Province, and studied years of variation characteristics of haze weather in Hubei Province. The results showed that the average annual haze days showed a fluctuant rising trend in whole from 1980 to 2012, but there were many peak value and valley value during the whole changing process; haze days of most stations showed an increasing trend, among which the stations with less than50 d haze days had a more obvious increasing trend, and the spatial distribution of annual mean haze days had distinct inhomogeneity. Haze days of Hubei Province presented the distribution characteristics of more in autumn and winter, and less in spring and summer, in which haze days during December-January were the most,and haze days during July-August were the least. Terrain had a big impact on local haze days, piedmont leeward zones were prone to haze days, mountainous regions were just the opposite. The research suggested that we should combine different situations with different stations instead of exclusively from the mean value of multiple stations when we analyze the mean change of haze days in a broader area, to investigate the overall changing trend and the reasons.展开更多
Objective To determine the levels of CC chemokine ligand 5 (CCL5) in serum and synovial fluid (SF) from patients with rheumatoid arthritis (RA) and their relations with disease activity and medication. Methods CCL5 in...Objective To determine the levels of CC chemokine ligand 5 (CCL5) in serum and synovial fluid (SF) from patients with rheumatoid arthritis (RA) and their relations with disease activity and medication. Methods CCL5 in serum and SF was quantified by enzyme-linked immunosorbent assay (ELISA) in 28 RA patients and 21 osteoarthritis (OA) patients. In RA patients, the correlations of CCL5 levels in serum and SF with disease activity were analyzed. Meanwhile, the serum CCL5 levels among RA patients treated with disease-modifying antirheumatic drugs (DMARDs), Tripterygium Glucosides, and other Chinese herbs without disease-modifying effects were also compared. Results CCL5 levels in both serum and SF of RA patients were significantly higher than those of OA patients (P<0.05). Moreover, the level of CCL5 was higher in SF than that in serum of RA patients (P<0.01). Serum CCL5 level was correlated significantly with the number of swollen joints (r=0.3329, P<0.05), erythrocyte sedimentation rate (r=0.4001, P<0.05), and C reactive protein (r=0.3735, P<0.01). In addition, the level of CCL5 had a trend of lower in patients treated with DMARDs or Tripterygium Glucosides than those treated with other Chinese herbs, although the difference was not significant among those patients due to the small number of patients in each group. Conclusions In RA patients, the expression of CCL5 increases and correlates with some clinical and laboratory parameters of RA, which indicate that CCL5 plays an important role in RA and may serve as a useful marker of disease activity. DMARDs and Tripterygium Glucosides might exert their clinical effects through reducing CCL5 production in RA.展开更多
基金jointly supported by the National Nature Science Foundation of China [grant number 42088101]NOAA [grant number NA18OAR4310298]+2 种基金the National Science Foundation (United States)[grant number AGS-2006553]the Educational Commission of Anhui Province of China [grant numbers KJ2021A1079 and KJ2021A1078]the Science and technology project of Chuzhou City of China [grant number 2021ZD007]。
文摘The combined effects of vertical overturning circulation(VOC) zonal length scale and moist static energy(MSE)tendency zonal asymmetry on MJO phase speed were investigated based on diagnosis of ERA-Interim data over a 40-year period(1979-2019).In a key region(80°-100°E),128 MJO events were selected.It was found that the larger the VOC zonal length scale,the faster the MJO eastward propagation.The correlation coefficient between them was 0.52,exceeding the 99% confidence level.A significant positive correlation(0.59) was also identified between the phase speed and MSE tendency zonal asymmetry.A linear regression model based on the aforementioned two parameters was constructed,and the phase speed could be estimated based on the model.The correlation coefficient between the reconstructed phase speed and its observed counterpart was 0.73,exceeding the 99% confidence level with an F-test.A composite analysis of the fast and slow groups indicated that the VOC zonal length scale was modulated by the background state.An El Nino(La Ni?a)-like SST pattern and associated precipitation anomalies promoted a larger(smaller) VOC zonal length scale and thus a faster(slower)propagation speed.A sensitivity test with a reference point in a different longitudinal zone(120°-140°E) was conducted.Again,there were significant relationships between the MJO phase speed and the two parameters.The correlation between the reconstructed and observed phase speed was 0.67,exceeding the 99% confidence level.
文摘This paper, using the method of "the combination of 14 o'clock relative humidity, visibility and weather phenomena", selected haze days during 1980-2012 from 13 stations of Hubei Province, and studied years of variation characteristics of haze weather in Hubei Province. The results showed that the average annual haze days showed a fluctuant rising trend in whole from 1980 to 2012, but there were many peak value and valley value during the whole changing process; haze days of most stations showed an increasing trend, among which the stations with less than50 d haze days had a more obvious increasing trend, and the spatial distribution of annual mean haze days had distinct inhomogeneity. Haze days of Hubei Province presented the distribution characteristics of more in autumn and winter, and less in spring and summer, in which haze days during December-January were the most,and haze days during July-August were the least. Terrain had a big impact on local haze days, piedmont leeward zones were prone to haze days, mountainous regions were just the opposite. The research suggested that we should combine different situations with different stations instead of exclusively from the mean value of multiple stations when we analyze the mean change of haze days in a broader area, to investigate the overall changing trend and the reasons.
基金Supported by a grant from the Department of Health of Sichuan province (010061)
文摘Objective To determine the levels of CC chemokine ligand 5 (CCL5) in serum and synovial fluid (SF) from patients with rheumatoid arthritis (RA) and their relations with disease activity and medication. Methods CCL5 in serum and SF was quantified by enzyme-linked immunosorbent assay (ELISA) in 28 RA patients and 21 osteoarthritis (OA) patients. In RA patients, the correlations of CCL5 levels in serum and SF with disease activity were analyzed. Meanwhile, the serum CCL5 levels among RA patients treated with disease-modifying antirheumatic drugs (DMARDs), Tripterygium Glucosides, and other Chinese herbs without disease-modifying effects were also compared. Results CCL5 levels in both serum and SF of RA patients were significantly higher than those of OA patients (P<0.05). Moreover, the level of CCL5 was higher in SF than that in serum of RA patients (P<0.01). Serum CCL5 level was correlated significantly with the number of swollen joints (r=0.3329, P<0.05), erythrocyte sedimentation rate (r=0.4001, P<0.05), and C reactive protein (r=0.3735, P<0.01). In addition, the level of CCL5 had a trend of lower in patients treated with DMARDs or Tripterygium Glucosides than those treated with other Chinese herbs, although the difference was not significant among those patients due to the small number of patients in each group. Conclusions In RA patients, the expression of CCL5 increases and correlates with some clinical and laboratory parameters of RA, which indicate that CCL5 plays an important role in RA and may serve as a useful marker of disease activity. DMARDs and Tripterygium Glucosides might exert their clinical effects through reducing CCL5 production in RA.
