Background: Advances in gastrointestinal endoscopy have resulted in endoscopic mucosal resection becoming the main therapy for many early gastric cancers confined to the mucosa and, in some cases, of minimal submucosa...Background: Advances in gastrointestinal endoscopy have resulted in endoscopic mucosal resection becoming the main therapy for many early gastric cancers confined to the mucosa and, in some cases, of minimal submucosal invasion. Thus, preoperative determination of the depth of the cancer is important. We compared the results of high-frequency ultrasound probe sonography with those of histologic study to clarify the usefulness of identifying of submucosal invasion and determining the depth of early gastric cancer. Methods: Subjects were 295 patients diagnosed with early gastric cancer who had undergone endoscopic mucosal or surgical resection. High-frequency ultrasound probe sonographic findings were compared with histologic findings. Results: The muscularis mucosae was visualized in 63%of cases of early gastric cancer. By construction on receiver operator characteristics curve, we determined that submucosal invasive cancer could be diagnosed by high frequency ultrasound probe sonography to a depth of about 600 μm. There was no case in which invasion deeper than 1000 μm was diagnosed as a hypoechoic area limited to the mucosal layer or a fan-shaped hypoechoic area in the submucosal layer. The depth of early gastric cancer was accurately determined in 90%of cases. Conclusions: High-frequency ultrasound probe is a useful tool for accurately determining the depth of invasion of early gastric cancer when its limitations are understood.展开更多
背景与目的:内镜超声是目前临床上广泛运用的胃癌术前分期的检查方法。内镜下黏膜切除术及黏膜剥离术在治疗早期胃癌中已广泛开展,因此提高胃癌术前分期的准确性,尤其是早期胃癌的诊断率。本文旨在探讨高频小探头内镜超声(high frequenc...背景与目的:内镜超声是目前临床上广泛运用的胃癌术前分期的检查方法。内镜下黏膜切除术及黏膜剥离术在治疗早期胃癌中已广泛开展,因此提高胃癌术前分期的准确性,尤其是早期胃癌的诊断率。本文旨在探讨高频小探头内镜超声(high frequency endoscopic ultrasound mini probe,UMP)在胃癌术前T分期中的临床应用价值。方法:2008年10月-2009年4月,对63例胃癌患者术前分别行高频小探头内镜超声和多层螺旋CT(multislice spiral CT,MSCT)检查,并与手术后病理进行对照。结果:UMP与MSCT对T分期判断准确率分别为82.26%(51/62)和88.71%(55/62),差异无统计学意义(P>0.05)。UMP与MSCT对早期胃癌的诊断准确率分别为100.00%和88.89%;进展期胃癌的诊断准确率则是79.25%和88.68%。结论:UMP对早期胃癌诊断具有重要价值,因此对于内镜下查找浅表病灶应首选UMP。展开更多
文摘Background: Advances in gastrointestinal endoscopy have resulted in endoscopic mucosal resection becoming the main therapy for many early gastric cancers confined to the mucosa and, in some cases, of minimal submucosal invasion. Thus, preoperative determination of the depth of the cancer is important. We compared the results of high-frequency ultrasound probe sonography with those of histologic study to clarify the usefulness of identifying of submucosal invasion and determining the depth of early gastric cancer. Methods: Subjects were 295 patients diagnosed with early gastric cancer who had undergone endoscopic mucosal or surgical resection. High-frequency ultrasound probe sonographic findings were compared with histologic findings. Results: The muscularis mucosae was visualized in 63%of cases of early gastric cancer. By construction on receiver operator characteristics curve, we determined that submucosal invasive cancer could be diagnosed by high frequency ultrasound probe sonography to a depth of about 600 μm. There was no case in which invasion deeper than 1000 μm was diagnosed as a hypoechoic area limited to the mucosal layer or a fan-shaped hypoechoic area in the submucosal layer. The depth of early gastric cancer was accurately determined in 90%of cases. Conclusions: High-frequency ultrasound probe is a useful tool for accurately determining the depth of invasion of early gastric cancer when its limitations are understood.
文摘背景与目的:内镜超声是目前临床上广泛运用的胃癌术前分期的检查方法。内镜下黏膜切除术及黏膜剥离术在治疗早期胃癌中已广泛开展,因此提高胃癌术前分期的准确性,尤其是早期胃癌的诊断率。本文旨在探讨高频小探头内镜超声(high frequency endoscopic ultrasound mini probe,UMP)在胃癌术前T分期中的临床应用价值。方法:2008年10月-2009年4月,对63例胃癌患者术前分别行高频小探头内镜超声和多层螺旋CT(multislice spiral CT,MSCT)检查,并与手术后病理进行对照。结果:UMP与MSCT对T分期判断准确率分别为82.26%(51/62)和88.71%(55/62),差异无统计学意义(P>0.05)。UMP与MSCT对早期胃癌的诊断准确率分别为100.00%和88.89%;进展期胃癌的诊断准确率则是79.25%和88.68%。结论:UMP对早期胃癌诊断具有重要价值,因此对于内镜下查找浅表病灶应首选UMP。
