目的:评价眼针联合鱼腥草注射液超声雾化熏眼治疗干眼症的临床效果。方法:前瞻性选取2022.06~2023.12于我院眼科就诊的干眼症患者62例,采用随机数字表法分为治疗组和对照组,治疗组采用眼针联合鱼腥草注射液超声雾化熏眼,对照组采用单纯...目的:评价眼针联合鱼腥草注射液超声雾化熏眼治疗干眼症的临床效果。方法:前瞻性选取2022.06~2023.12于我院眼科就诊的干眼症患者62例,采用随机数字表法分为治疗组和对照组,治疗组采用眼针联合鱼腥草注射液超声雾化熏眼,对照组采用单纯鱼腥草注射液超声雾化熏眼,每周治疗5天,连续治疗4周。比较两组治疗前后的眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验(SIT)、泪河高度(TMH)及临床疗效。结果:两组患者治疗前OSDI、BUT、SIT、TMH基线水平无统计学差异(P > 0.05)。两组治疗后OSDI评分均下降,且治疗组OSDI评分显著低于对照组(P P P P P < 0.05)。结论:眼针联合鱼腥草注射液雾化熏眼治疗干眼症能够有效改善干眼症患者眼部症状,稳定泪膜状态,提高临床疗效。展开更多
Aim To find corresponding relationship between the fingerprint of Houttuynia cordata injections from different factories and their effects.Methods Houttuynia cordata injections from six different factories were determ...Aim To find corresponding relationship between the fingerprint of Houttuynia cordata injections from different factories and their effects.Methods Houttuynia cordata injections from six different factories were determined by gas chromatography(GC) and gas chromatography-mass spectra(GC-MS),and GC fingerprints were classified by hierarchical clustering.The anti-inflammatory activity of Houttuynia cordata injections was characterized through the rat pleurisy model induced by carrageenin and the mice ear edema model by dimethylbenzene.Results The anti-inflammatory effect of the injections from the first class factories on the two model was significant,while those from the second class not.(GC-MS) analysis result indicated that main effect compounds in Houttuynia cordata injections are methyl(n-nonyl ketone),decanoylacetaldehyde,lauryl aldehyde,capryl aldehyde,(β-pinene),(βlinalool),(1-nonanol),(4-terpineol),α-terpineol,bornyl acetate, n-decanoic acid and acetic acid,geraniol ester etc.Conclusion There is corresponding relationship between the fingerprint of Houttuynia cordata injections and effect to a certain extent.展开更多
文摘目的:评价眼针联合鱼腥草注射液超声雾化熏眼治疗干眼症的临床效果。方法:前瞻性选取2022.06~2023.12于我院眼科就诊的干眼症患者62例,采用随机数字表法分为治疗组和对照组,治疗组采用眼针联合鱼腥草注射液超声雾化熏眼,对照组采用单纯鱼腥草注射液超声雾化熏眼,每周治疗5天,连续治疗4周。比较两组治疗前后的眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验(SIT)、泪河高度(TMH)及临床疗效。结果:两组患者治疗前OSDI、BUT、SIT、TMH基线水平无统计学差异(P > 0.05)。两组治疗后OSDI评分均下降,且治疗组OSDI评分显著低于对照组(P P P P P < 0.05)。结论:眼针联合鱼腥草注射液雾化熏眼治疗干眼症能够有效改善干眼症患者眼部症状,稳定泪膜状态,提高临床疗效。
文摘Aim To find corresponding relationship between the fingerprint of Houttuynia cordata injections from different factories and their effects.Methods Houttuynia cordata injections from six different factories were determined by gas chromatography(GC) and gas chromatography-mass spectra(GC-MS),and GC fingerprints were classified by hierarchical clustering.The anti-inflammatory activity of Houttuynia cordata injections was characterized through the rat pleurisy model induced by carrageenin and the mice ear edema model by dimethylbenzene.Results The anti-inflammatory effect of the injections from the first class factories on the two model was significant,while those from the second class not.(GC-MS) analysis result indicated that main effect compounds in Houttuynia cordata injections are methyl(n-nonyl ketone),decanoylacetaldehyde,lauryl aldehyde,capryl aldehyde,(β-pinene),(βlinalool),(1-nonanol),(4-terpineol),α-terpineol,bornyl acetate, n-decanoic acid and acetic acid,geraniol ester etc.Conclusion There is corresponding relationship between the fingerprint of Houttuynia cordata injections and effect to a certain extent.