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A New Synthetic Route for 2,4-Dibromo-5-fluorobenzoic Acid
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作者 Qiong ZHENG Chi HUANG +3 位作者 Chong Wen XU Guang Yong XIE Gao Qing CHEN Yuan Yin CHEN (College of Chemistry, Wuhan University, Wuhan 430072) 《Chinese Chemical Letters》 SCIE CAS CSCD 1998年第9期797-798,共2页
A convenient and practical synthetic route for 2,4-dibromo-5-fluorobenzoic acid is described. Two intermediates, 2,4-dibromo-5-fluorobenzonitrile and 2,4-dibromo-5-fluorobenzamide, have not been reported before. This ... A convenient and practical synthetic route for 2,4-dibromo-5-fluorobenzoic acid is described. Two intermediates, 2,4-dibromo-5-fluorobenzonitrile and 2,4-dibromo-5-fluorobenzamide, have not been reported before. This route can be easily industrialized. 展开更多
关键词 2 4-dibromo-5-fluorobenzoic acid 2 4-dibromo-5-fluorobenzonitrile AMMOXIDATION FLUOROQUINOLONE
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Synthesis of 2, 4-Dibromo-5-Fluorobenzonitrile
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作者 Zheng Qiong Huang Chi +2 位作者 Xu Chongwen Xie Guangyong Chen Yuanyin(College of Chemistry, Wuhan University, Wuhan 430072. China) 《Wuhan University Journal of Natural Sciences》 CAS 1998年第4期509-510,共2页
2,4-Dibromo-5-fluorobenzonitrile has been synthesized for the first time (81.5% yield). It may be used in synthesizing 2,4-dibromo-5-fluorobenzoic acid, the intermediates of fluoroquinolones. The ammoxidation procedur... 2,4-Dibromo-5-fluorobenzonitrile has been synthesized for the first time (81.5% yield). It may be used in synthesizing 2,4-dibromo-5-fluorobenzoic acid, the intermediates of fluoroquinolones. The ammoxidation procedure for preparation of the nitrile has been described in detail. 展开更多
关键词 AMMOXIDATION 2 4-dibromo-5-fluorobenzonitrile 2 4-dibromo-5-fluorobenzoic acid FLUOROQUINOLONE
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