Objective:To investigate the potential mechanism of electroacupuncture(EA)at bilateral Fengchi(GB20)in treating cerebral ischemia-reperfusion injury and to provide a scientific basis for future experimental research a...Objective:To investigate the potential mechanism of electroacupuncture(EA)at bilateral Fengchi(GB20)in treating cerebral ischemia-reperfusion injury and to provide a scientific basis for future experimental research and clinical applications.Methods:Forty male specific-pathogen-free Sprague-Dawley rats were randomly divided into four groups:a normal group,a normal with EA group,a model group,and a model with EA group,with 10 rats in each group.The normal group received no intervention.The normal with EA group received EA at bilateral Fengchi(GB20).The model group underwent middle cerebral artery occlusion(MCAO)using the suture.The model with EA group underwent MCAO and received EA at bilateral Fengchi(GB20).Cerebral blood flow was monitored using a laser Doppler cerebral blood flow meter.Neurologic damage was assessed using the neurologic deficit score,and motor ability was observed using the CatWalk gait system.The expression of glial fibrillary acidic protein(GFAP)and neuronal nuclei(NeuN)protein,the neuron markers,was detected by Western blotting.The protein expression levels of GFAP and NeuN,as well as the number of positive cells in the motor cortex,were detected using immunofluorescence.Results:Compared to the normal group,the cerebral blood flow values in the model group and the model with EA group decreased by more than 50%during the modeling process(P<0.01)and returned to pre-modeling levels after reperfusion(P>0.05).The neurologic deficit score increased(P<0.05),the average motor velocity decreased(P<0.05),GFAP protein expression and the number of positive cells in the motor cortex increased(P<0.05),and the NeuN protein expression and the number of positive cells decreased(P<0.05)in the model group.Compared to the model group,the neurologic deficit score decreased(P<0.05),the average motor velocity accelerated(P<0.05),GFAP and NeuN protein expression and the number of positive cells in the motor cortex increased(P<0.01)in the model with EA group.Conclusion:EA at bilateral Fengchi(GB20)can reduce neuronal loss and increase GFAP and NeuN protein expression in the motor cortex of rats after ischemia-reperfusion,improve the motor function after ischemic stroke,and accelerate the recovery of balance and stability of the affected limbs.展开更多
The article introduces Prof.Weijia’s experience in using Fengchi(GB 20)totreat gastric ulcer,bronchial asthma,sciatica,and alopecia,etc.He considers that the point has seven general functions of dispelling pathogenic...The article introduces Prof.Weijia’s experience in using Fengchi(GB 20)totreat gastric ulcer,bronchial asthma,sciatica,and alopecia,etc.He considers that the point has seven general functions of dispelling pathogenic wind,purging pathogenic fire,relieving the depressedliver-Qi,resolving the phlegm,activating the blood,tranquilizing the mind,and checking spasm andconvulsion.It also introduces some common diseases treated with needling Fengchi and adjunctpoints,manipulations,and precautions,etc.It Is a comparatively comprehensive summary of Prof.Wei Jia’s individual experience in wonderfully using Fengchi.展开更多
The article introduces the writers’ experience in using Fengchi(GB 20) to treat sciatica,gastric ulcer and bronchial asthma, etc. The writers consider that the point has seven general functions of dispelling pathogen...The article introduces the writers’ experience in using Fengchi(GB 20) to treat sciatica,gastric ulcer and bronchial asthma, etc. The writers consider that the point has seven general functions of dispelling pathogenic wind, purging pathogenic fire, relieving the depressed liver-qi, resolvingthe phlegm, activating the blood, tranquilizing the mind, and checking spasm and c0nvulsion. It alsointroduces the manipulations and precautions of needling Fengchi.展开更多
Objective：To observe the effect of acupuncture of Fengchi （风池 GB 20） on blood pressure, serum IL-6 and plasma endothelin （ET） contents in patients with hypertension. Methods： Thirty cases of hy-pertension pati...Objective：To observe the effect of acupuncture of Fengchi （风池 GB 20） on blood pressure, serum IL-6 and plasma endothelin （ET） contents in patients with hypertension. Methods： Thirty cases of hy-pertension patients were made up of treatment group and treated with acupuncture of Fengchi （GB 20） ; while 20 healthy subjects were made up of control group. Blood pressure was determined before and after the treatment. Fasting blood samples were taken from the cubital venous vessel for detecting serum interleukin （IL）-6 and plasma ET contents with radioimmunoassay before and after acupuncture treatment. Results： Before the treatment, in hypertension patients, serum IL-6 and plasma ET levels were significant higher thanthose in healthy subjects （P〈 0.01 ）; while after the treatment, blood pressure of treatment group declined significantly （ P 〈 0.01 ）, serum IL-6 and plasma ET levels decreased considerably （ P 〈 0.01 ）. Conclusion： Acupuncture of Fengchi （GB 20） can lower blood pressure, regulate cellular immunity and secretion functions of the vascular endothelial cells in hypertension patients.展开更多
Objective: To explore therapeutic method for occipital neuralgia. Methods: A total of 90 occipital neuralgia patients were randomly divided into treatment group (n=60 cases) and control group (n=30). In treatment grou...Objective: To explore therapeutic method for occipital neuralgia. Methods: A total of 90 occipital neuralgia patients were randomly divided into treatment group (n=60 cases) and control group (n=30). In treatment group, Dazhui (GV 14) was punctured and stimulated with reinforcing method, and Fengchi (GB 20) punctured and stimulated with reducing needling method. In control group, the tender point was punctured and stimulated with reducing needling method. The acupuncture needles were retained for 30 min and the treatment was conducted once daily, with 10 times being a therapeutic course. Results: After one session of treatment, the markedly effective rates of treatment and control groups were 98% and 57% respectively. Comparison between two groups showed a considerable difference in the therapeutic effect (P<0.05). Conclusion: Acupuncture of Dazhui (GV 14) and Fengchi (GB 20) are effective in the treatment of occipital neuralgia.展开更多
目的:观察风池穴水针刀治疗颈源性头痛(cervicogenic headache,CEH)的临床疗效。方法:选取淄博市中西医结合医院针灸科、脑病科2020年3月至2021年4月收治的CEH患者120例,按照随机数字表法分为治疗组、针刺组和西药组,每组40例。针刺组...目的:观察风池穴水针刀治疗颈源性头痛(cervicogenic headache,CEH)的临床疗效。方法:选取淄博市中西医结合医院针灸科、脑病科2020年3月至2021年4月收治的CEH患者120例,按照随机数字表法分为治疗组、针刺组和西药组,每组40例。针刺组给予常规针刺治疗,西药组给予口服双氯芬酸钠肠溶缓释胶囊治疗,治疗组给予风池穴水针刀治疗。观察3组患者治疗前后颈椎活动度(cervical range of motion,ROM)评分、头痛程度评分、头痛持续时间评分、头痛指数评分变化情况,治疗后3个月随访进行远期疗效评价。结果:3组患者治疗后头痛程度评分、头痛持续时间评分、头痛指数评分均低于治疗前,差异有统计学意义(P<0.01),治疗组和西药组治疗1个疗程、2个疗程后头痛程度评分、头痛持续时间评分、头痛指数均低于针刺组,差异有统计学意义(P<0.01),但治疗组与西药组比较,差异无统计学意义(P>0.05)。3组患者治疗1个疗程、治疗2个疗程后ROM评分均低于治疗前,差异有统计学意义(P<0.01),治疗组治疗1个疗程、治疗2个疗程后ROM评分低于针刺组、西药组,差异有统计学意义(P<0.05),针刺组治疗2个疗程后ROM评分低于西药组,差异有统计学意义(P<0.05)。治疗组有效率为87.5%,针刺组有效率为65.0%,西药组有效率为47.5%,治疗组有效率高于西药组、针刺组,差异具有统计学意义(P<0.01)。结论:水针刀风池穴治疗颈源性头痛即时镇痛效果好,远期临床疗效高,能改善患者颈椎活动度。展开更多
Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the p...Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the present study,we assessed the safety of acupuncture at Fengchi.Laboratory tests and adverse event reports were used to evaluate the safety of different acupuncture manipulations for the treatment of posterior circulation ischemia with vertigo.A total of 136 patients were randomly assigned to four groups.Verum acupuncture was conducted with different needle insertion directions（contralateral paropia or prominentia laryngea） and different needle twisting frequencies（60 or 120 times/minute） at Fengchi and matching acupoints（for example,Zhongwan [CV12],Qihai [CV6],Zusanli [ST36],and Fenglong [ST40]）.The patients received 14 treatments over 3–4 weeks.Routine blood analysis,hepatic and renal function tests,urine and feces tests and electrocardiography were performed before the first treatment session and after the final session.Adverse events were recorded after every session.Of the 136 patients,120 completed the study.There were no significant differences between pretreatment and posttreatment test results in any of the groups.Only five patients suffered from minor adverse events（needling pain,slight hematoma and transient chest tightness）.No serious adverse events were found.Our results indicate that a 14-session course of needling at Fengchi is relatively safe for treating posterior circulation ischemia with vertigo.展开更多
文摘Objective:To investigate the potential mechanism of electroacupuncture(EA)at bilateral Fengchi(GB20)in treating cerebral ischemia-reperfusion injury and to provide a scientific basis for future experimental research and clinical applications.Methods:Forty male specific-pathogen-free Sprague-Dawley rats were randomly divided into four groups:a normal group,a normal with EA group,a model group,and a model with EA group,with 10 rats in each group.The normal group received no intervention.The normal with EA group received EA at bilateral Fengchi(GB20).The model group underwent middle cerebral artery occlusion(MCAO)using the suture.The model with EA group underwent MCAO and received EA at bilateral Fengchi(GB20).Cerebral blood flow was monitored using a laser Doppler cerebral blood flow meter.Neurologic damage was assessed using the neurologic deficit score,and motor ability was observed using the CatWalk gait system.The expression of glial fibrillary acidic protein(GFAP)and neuronal nuclei(NeuN)protein,the neuron markers,was detected by Western blotting.The protein expression levels of GFAP and NeuN,as well as the number of positive cells in the motor cortex,were detected using immunofluorescence.Results:Compared to the normal group,the cerebral blood flow values in the model group and the model with EA group decreased by more than 50%during the modeling process(P<0.01)and returned to pre-modeling levels after reperfusion(P>0.05).The neurologic deficit score increased(P<0.05),the average motor velocity decreased(P<0.05),GFAP protein expression and the number of positive cells in the motor cortex increased(P<0.05),and the NeuN protein expression and the number of positive cells decreased(P<0.05)in the model group.Compared to the model group,the neurologic deficit score decreased(P<0.05),the average motor velocity accelerated(P<0.05),GFAP and NeuN protein expression and the number of positive cells in the motor cortex increased(P<0.01)in the model with EA group.Conclusion:EA at bilateral Fengchi(GB20)can reduce neuronal loss and increase GFAP and NeuN protein expression in the motor cortex of rats after ischemia-reperfusion,improve the motor function after ischemic stroke,and accelerate the recovery of balance and stability of the affected limbs.
文摘The article introduces Prof.Weijia’s experience in using Fengchi(GB 20)totreat gastric ulcer,bronchial asthma,sciatica,and alopecia,etc.He considers that the point has seven general functions of dispelling pathogenic wind,purging pathogenic fire,relieving the depressedliver-Qi,resolving the phlegm,activating the blood,tranquilizing the mind,and checking spasm andconvulsion.It also introduces some common diseases treated with needling Fengchi and adjunctpoints,manipulations,and precautions,etc.It Is a comparatively comprehensive summary of Prof.Wei Jia’s individual experience in wonderfully using Fengchi.
文摘The article introduces the writers’ experience in using Fengchi(GB 20) to treat sciatica,gastric ulcer and bronchial asthma, etc. The writers consider that the point has seven general functions of dispelling pathogenic wind, purging pathogenic fire, relieving the depressed liver-qi, resolvingthe phlegm, activating the blood, tranquilizing the mind, and checking spasm and c0nvulsion. It alsointroduces the manipulations and precautions of needling Fengchi.
文摘Objective：To observe the effect of acupuncture of Fengchi （风池 GB 20） on blood pressure, serum IL-6 and plasma endothelin （ET） contents in patients with hypertension. Methods： Thirty cases of hy-pertension patients were made up of treatment group and treated with acupuncture of Fengchi （GB 20） ; while 20 healthy subjects were made up of control group. Blood pressure was determined before and after the treatment. Fasting blood samples were taken from the cubital venous vessel for detecting serum interleukin （IL）-6 and plasma ET contents with radioimmunoassay before and after acupuncture treatment. Results： Before the treatment, in hypertension patients, serum IL-6 and plasma ET levels were significant higher thanthose in healthy subjects （P〈 0.01 ）; while after the treatment, blood pressure of treatment group declined significantly （ P 〈 0.01 ）, serum IL-6 and plasma ET levels decreased considerably （ P 〈 0.01 ）. Conclusion： Acupuncture of Fengchi （GB 20） can lower blood pressure, regulate cellular immunity and secretion functions of the vascular endothelial cells in hypertension patients.
文摘Objective: To explore therapeutic method for occipital neuralgia. Methods: A total of 90 occipital neuralgia patients were randomly divided into treatment group (n=60 cases) and control group (n=30). In treatment group, Dazhui (GV 14) was punctured and stimulated with reinforcing method, and Fengchi (GB 20) punctured and stimulated with reducing needling method. In control group, the tender point was punctured and stimulated with reducing needling method. The acupuncture needles were retained for 30 min and the treatment was conducted once daily, with 10 times being a therapeutic course. Results: After one session of treatment, the markedly effective rates of treatment and control groups were 98% and 57% respectively. Comparison between two groups showed a considerable difference in the therapeutic effect (P<0.05). Conclusion: Acupuncture of Dazhui (GV 14) and Fengchi (GB 20) are effective in the treatment of occipital neuralgia.
文摘目的:观察风池穴水针刀治疗颈源性头痛(cervicogenic headache,CEH)的临床疗效。方法:选取淄博市中西医结合医院针灸科、脑病科2020年3月至2021年4月收治的CEH患者120例,按照随机数字表法分为治疗组、针刺组和西药组,每组40例。针刺组给予常规针刺治疗,西药组给予口服双氯芬酸钠肠溶缓释胶囊治疗,治疗组给予风池穴水针刀治疗。观察3组患者治疗前后颈椎活动度(cervical range of motion,ROM)评分、头痛程度评分、头痛持续时间评分、头痛指数评分变化情况,治疗后3个月随访进行远期疗效评价。结果:3组患者治疗后头痛程度评分、头痛持续时间评分、头痛指数评分均低于治疗前,差异有统计学意义(P<0.01),治疗组和西药组治疗1个疗程、2个疗程后头痛程度评分、头痛持续时间评分、头痛指数均低于针刺组,差异有统计学意义(P<0.01),但治疗组与西药组比较,差异无统计学意义(P>0.05)。3组患者治疗1个疗程、治疗2个疗程后ROM评分均低于治疗前,差异有统计学意义(P<0.01),治疗组治疗1个疗程、治疗2个疗程后ROM评分低于针刺组、西药组,差异有统计学意义(P<0.05),针刺组治疗2个疗程后ROM评分低于西药组,差异有统计学意义(P<0.05)。治疗组有效率为87.5%,针刺组有效率为65.0%,西药组有效率为47.5%,治疗组有效率高于西药组、针刺组,差异具有统计学意义(P<0.01)。结论:水针刀风池穴治疗颈源性头痛即时镇痛效果好,远期临床疗效高,能改善患者颈椎活动度。
基金supported by the National Basic Research Program of China(973 Program),No.2010CB530506
文摘Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the present study,we assessed the safety of acupuncture at Fengchi.Laboratory tests and adverse event reports were used to evaluate the safety of different acupuncture manipulations for the treatment of posterior circulation ischemia with vertigo.A total of 136 patients were randomly assigned to four groups.Verum acupuncture was conducted with different needle insertion directions（contralateral paropia or prominentia laryngea） and different needle twisting frequencies（60 or 120 times/minute） at Fengchi and matching acupoints（for example,Zhongwan [CV12],Qihai [CV6],Zusanli [ST36],and Fenglong [ST40]）.The patients received 14 treatments over 3–4 weeks.Routine blood analysis,hepatic and renal function tests,urine and feces tests and electrocardiography were performed before the first treatment session and after the final session.Adverse events were recorded after every session.Of the 136 patients,120 completed the study.There were no significant differences between pretreatment and posttreatment test results in any of the groups.Only five patients suffered from minor adverse events（needling pain,slight hematoma and transient chest tightness）.No serious adverse events were found.Our results indicate that a 14-session course of needling at Fengchi is relatively safe for treating posterior circulation ischemia with vertigo.
