BACKGROUND Postoperative unobstructed drainage is an important measure for avoiding hematoma formation and preventing complications from anterior cervical surgery.AIM To discuss the characteristics and key points of c...BACKGROUND Postoperative unobstructed drainage is an important measure for avoiding hematoma formation and preventing complications from anterior cervical surgery.AIM To discuss the characteristics and key points of clinical management of two types of commonly used negative pressure drainage systems in clinical settings.METHODS Two types of commonly used silica gel negative pressure drainage balls and a type of gastrointestinal decompression apparatus were fully emptied and then injected with different amounts of water and air.Following this,the negative pressure values of the three devices were measured.Meanwhile,we undertook a retrospective analysis of the clinical data of 1328 patients who had been treated with different negative pressure drainage apparatuses during their anterior cervical surgery in our department between January 2007 and January 2018.RESULTS As the amount of injected air or water increased,the negative pressure of the silica gel negative pressure drainage ball decreased rapidly,dropping to zero when 150 mL of water or air was injected.In contrast,the negative pressure of gastrointestinal decompression apparatus decreased slowly,maintaining an ideal value even when 300 mL of water or air was injected.And statistical analysis demonstrated that patients who had been treated with the gastrointestinal decompression apparatus were less likely to develop severe complications than those who had been treated with the silica gel negative pressure drainage ball(P<0.05).CONCLUSION This study showed that the gastrointestinal decompression apparatus has the advantages of large suction capacity,long duration of continuous negative pressure,and good drainage effect,all of which are the favorable factors for the use of this apparatus for negative pressure drainage in anterior cervical surgery.展开更多
目的探究显微镜辅助颈椎前路减压内固定融合术(anterior cervical decompression and fusion,ACDF)在颈椎病治疗中的效果。方法回顾性分析烟台业达医院2019年2月~2020年6月收治的78例颈椎病患者资料,按手术方式的不同分成A、B组。A组38...目的探究显微镜辅助颈椎前路减压内固定融合术(anterior cervical decompression and fusion,ACDF)在颈椎病治疗中的效果。方法回顾性分析烟台业达医院2019年2月~2020年6月收治的78例颈椎病患者资料,按手术方式的不同分成A、B组。A组38例实施标准开放ACDF治疗,B组40例实施显微镜辅助ACDF。观察并记录两组手术参数,统计并发症发生情况,采用数字分级评分法(numerical rating scale,NRS)、日本骨科协会评分(Japanese orthopaedic association score,JOA)分别对两组术前、术后1年的疼痛度、颈椎神经功能进行评定,测量颈椎Cobb角,并计算颈椎神经功能改善率。结果B组手术用时、术中失血量均较A组少(P<0.05),术后住院时间组间比较无统计学差异(P>0.05);A组发生2例脑脊液漏,B组无并发症发生,组间比较无统计学差异(P>0.05);与同组术前相比,两组术后1年NRS、JOA评分、颈椎Cobb角均明显改善(P<0.05),而组间上述指标比较均无统计学差异(P>0.05);A组颈椎神经功能改善率89.47%与B组的92.50%相比,无统计学差异(P>0.05)。结论对颈椎病患者实施显微镜辅助ACDF的治疗效果较好,且具有手术用时短、术中失血量少等优势。展开更多
目的观察脊髓型颈椎病患者接受颈前路椎间盘切除减压植骨融合术(anterior cervical discectomy and fusion,ACDF)术后的颈长肌和颈伸肌变化情况,并分析颈长肌和颈伸肌的术后变化与ACDF手术疗效的相关性。方法以该科2016年6月~2021年6月...目的观察脊髓型颈椎病患者接受颈前路椎间盘切除减压植骨融合术(anterior cervical discectomy and fusion,ACDF)术后的颈长肌和颈伸肌变化情况,并分析颈长肌和颈伸肌的术后变化与ACDF手术疗效的相关性。方法以该科2016年6月~2021年6月开展单节段ACDF手术的62例脊髓型颈椎病患者作为研究对象,分别于术前、术后3个月、术后1年和末次随访时,进行VAS评分、mJOA评分和NDI指数等疗效指标评价;同时,采用颈椎MRI T2加权像检查并测量其颈长肌和颈伸肌的横截面积(cross section area,CSA),颈长肌的最长径/最短径比值(ratio of long and short lines,RLS)以及颈长肌和颈伸肌的容积。采用Pearson相关性系数对颈长肌和颈伸肌容积与上述疗效指标进行相关性分析。结果62例患者均成功完成单节段ACDF手术且获访24~30个月、平均25.9个月。与术前相比,患者术后3个月、1年和末次随访时的颈肩痛VAS评分、mJOA评分和NDI指数均显著改善(P<0.05)。末次随访时采用Odom标准评价,优38例,良22例,可2例。与术前相比,所有患者术后3个月、1年和末次随访时的颈长肌CSA和颈长肌容积均显著减少(P<0.05),术后3个月、1年和末次随访时的颈长肌RLS均显著增加(P<0.05);颈伸肌CSA和颈伸肌容积在手术前和术后各时间的变化无显著性差异(P>0.05)。经Pearson相关性分析显示,术后3个月、术后1年和末次随访的颈长肌容积与同时期的VAS评分和NDI指数均呈负相关性(P<0.05),与mJOA评分无明确相关性(P>0.05);而颈伸肌容积与同时期的VAS评分、NDI指数和mJOA评分均无明确的相关性(P>0.05)。结论脊髓型颈椎病患者行ACDF手术后,颈长肌可出现一定程度退变,颈伸肌的退变并不显著。颈长肌的退变可对手术预后产生不利影响。展开更多
目的探讨颈椎前路术后患者吞咽困难的危险因素。方法通过计算机检索中国知网(CNKI)、中国生物医学数据库(CBM)、维普(VIP)、万方、Embase、Web of Science、CINAHL、PubMed,、Cochrane Library等中英文数据库已发表的关于颈椎前路术后...目的探讨颈椎前路术后患者吞咽困难的危险因素。方法通过计算机检索中国知网(CNKI)、中国生物医学数据库(CBM)、维普(VIP)、万方、Embase、Web of Science、CINAHL、PubMed,、Cochrane Library等中英文数据库已发表的关于颈椎前路术后患者吞咽困难危险因素的病例对照研究,检索时间从建库开始到2023年7月。经文献筛选、质量评价、数据提取后运用Reman 5.3软件对数据进行Meta分析。结果最终纳入20篇病例对照研究,包括9篇中文文献和11篇英文文献,共计4161例受试对象。Meta分析结果显示:所纳入研究共计有10个危险因素具有统计学意义,分别为女性[OR=2.34,95%CI(1.82,3.01)]、高龄[OR=2.70,95%CI(1.87,3.91)]、吸烟[OR=1.43,95%CI(1.22,1.67)]、合并糖尿病[OR=2.87,95%CI(2.33,3.53)]、手术时间>2 h[OR=1.88,95%CI(1.56,2.23)]、手术节段高于C4[OR=1.92,95%CI(1.52,2.41)]、手术节段数>2[OR=4.64,95%CI(3.07,7.03)]、病程>8个月、颈前软组织过厚[OR=2.31,95%CI(1.06,3.35)]、dC2~7角>50[OR=1.39,95%CI(1.26,1.54)]。结论女性、高龄、吸烟、糖尿病、手术时间>2 h、手术节段高于C4、手术节段数>2、病程>8个月、颈前软组织过厚、dC2~7角>50的患者更易发生术后吞咽困难。展开更多
Objective To explore the efficacy and safety of different surgical approaches of cervical spondylotic myelopathy, and the predictive factors for the outcome of surgery. Methods Clinical data of 68 consecutive patients...Objective To explore the efficacy and safety of different surgical approaches of cervical spondylotic myelopathy, and the predictive factors for the outcome of surgery. Methods Clinical data of 68 consecutive patients who underwent surgical treatment from 2003-08-01 to 2006-12-01 were collected. The quantization of the efficacy of operation was made by applying Japanese Orthopedic Association (JOA) scoring system, based on which the recovery rate and satisfaction rate were calculated. In the patients who underwent anterior approach, we compared the recovery rate among the subgroups of different duration of symptoms, age at surgery and the severity of diseases. Any surgery-related complications were also noted. Results 73.5% (50/68) patients underwent anterior approach, with an average recovery rate of (68.21 ± 10.06)% and the satisfaction rate of 88.00%;20.6% patients (14/68) underwent posterior approach, with an average recovery rate of (64.03 ± 7.07)% and the satisfaction rate of 100%. The recovery rate had no significant difference in the two approaches. Only 4 patients (5.9%) underwent anterior and posterior combined approach, and the recovery rate and the satisfaction rate were 65.10% and 100%, respectively. In the group of patients who accepted anterior approach, no significant differences were found in the recovery rates of different age subgroups and different duration of symptom subgroups;the significant differences recovery rates between the moderate and severe subgroups were identified. Minor complications, such as asymptomatic screw misplacement, transient dysphagia/odynophagia, pain related to the donor site and axial syndrome, were observed in a few patients. Conclusion The JOA score can be improved by applying the appropriate approaches and the high recovery and satisfaction rates can be achieved at the same time. The efficacies of anterior and posterior approaches were similar. The complications of surgery were minor. In the patients who underwent anterior approach, the severity of diseases was a predictive factor for the outcome of surgery.展开更多
目的:通过三维有限元分析法比较双节段颈椎前路椎间盘切除融合术(anterior cervical discectomy and fusion,ACDF)应用零切迹(zero-profile,ZP)系统与钢板联合融合器(cage-and-plate,CP)固定后颈椎的生物力学变化。方法:采集1例正常成...目的:通过三维有限元分析法比较双节段颈椎前路椎间盘切除融合术(anterior cervical discectomy and fusion,ACDF)应用零切迹(zero-profile,ZP)系统与钢板联合融合器(cage-and-plate,CP)固定后颈椎的生物力学变化。方法:采集1例正常成年女性志愿者颈椎C3~C7节段CT扫描数据,建立C3~C7颈椎有限元模型并通过对比前期研究验证模型有效性。ZP固定模型与CP固定模型的手术节段均设定为C4/5与C5/6节段。在C3椎体上方施加轴向压缩负荷73.6N的模拟重力,并逐步施加1.8N·m的转矩,进而模拟屈伸、侧屈及轴向旋转等颈椎运动。测定并比较手术模型融合节段活动度(range of motion,ROM)、邻近节段椎间盘内应力、C5椎体及融合器装置应力。结果:CP固定模型融合节段的ROM在屈伸、侧屈、旋转位均明显小于ZP固定模型;CP固定模型相邻节段(C3/4、C6/7)的椎间盘内应力均远远高于ZP固定模型,两种模型融合节段上方的椎间盘内应力均高于融合节段下方;各工况下,ZP固定模型的C5椎体应力均明显高于CP固定模型,在前屈位时,两模型C5椎体应力最小(ZP固定模型为7.36Mpa,CP固定模型为2.01Mpa);各工况下,ZP固定模型的C4/5、C5/6椎间融合器的应力均大于CP固定模型。结论:相较于CP固定,ACDF术中应用ZP固定对手术节段的限制更小,手术节段ROM更高、微运动更多,融合器及中间椎体应力更大,术后更易发生融合器下沉甚至中间椎体塌陷。展开更多
基金Supported by the Multicenter Clinical Trial of hUC-MSCs in the Treatment of Late Chronic Spinal Cord Injury,No.2017YFA0105404the Key Discipline Construction Project of Pudong Health Bureau of Shanghai,No.PWZxk2017-08.
文摘BACKGROUND Postoperative unobstructed drainage is an important measure for avoiding hematoma formation and preventing complications from anterior cervical surgery.AIM To discuss the characteristics and key points of clinical management of two types of commonly used negative pressure drainage systems in clinical settings.METHODS Two types of commonly used silica gel negative pressure drainage balls and a type of gastrointestinal decompression apparatus were fully emptied and then injected with different amounts of water and air.Following this,the negative pressure values of the three devices were measured.Meanwhile,we undertook a retrospective analysis of the clinical data of 1328 patients who had been treated with different negative pressure drainage apparatuses during their anterior cervical surgery in our department between January 2007 and January 2018.RESULTS As the amount of injected air or water increased,the negative pressure of the silica gel negative pressure drainage ball decreased rapidly,dropping to zero when 150 mL of water or air was injected.In contrast,the negative pressure of gastrointestinal decompression apparatus decreased slowly,maintaining an ideal value even when 300 mL of water or air was injected.And statistical analysis demonstrated that patients who had been treated with the gastrointestinal decompression apparatus were less likely to develop severe complications than those who had been treated with the silica gel negative pressure drainage ball(P<0.05).CONCLUSION This study showed that the gastrointestinal decompression apparatus has the advantages of large suction capacity,long duration of continuous negative pressure,and good drainage effect,all of which are the favorable factors for the use of this apparatus for negative pressure drainage in anterior cervical surgery.
文摘目的探究显微镜辅助颈椎前路减压内固定融合术(anterior cervical decompression and fusion,ACDF)在颈椎病治疗中的效果。方法回顾性分析烟台业达医院2019年2月~2020年6月收治的78例颈椎病患者资料,按手术方式的不同分成A、B组。A组38例实施标准开放ACDF治疗,B组40例实施显微镜辅助ACDF。观察并记录两组手术参数,统计并发症发生情况,采用数字分级评分法(numerical rating scale,NRS)、日本骨科协会评分(Japanese orthopaedic association score,JOA)分别对两组术前、术后1年的疼痛度、颈椎神经功能进行评定,测量颈椎Cobb角,并计算颈椎神经功能改善率。结果B组手术用时、术中失血量均较A组少(P<0.05),术后住院时间组间比较无统计学差异(P>0.05);A组发生2例脑脊液漏,B组无并发症发生,组间比较无统计学差异(P>0.05);与同组术前相比,两组术后1年NRS、JOA评分、颈椎Cobb角均明显改善(P<0.05),而组间上述指标比较均无统计学差异(P>0.05);A组颈椎神经功能改善率89.47%与B组的92.50%相比,无统计学差异(P>0.05)。结论对颈椎病患者实施显微镜辅助ACDF的治疗效果较好,且具有手术用时短、术中失血量少等优势。
文摘目的观察脊髓型颈椎病患者接受颈前路椎间盘切除减压植骨融合术(anterior cervical discectomy and fusion,ACDF)术后的颈长肌和颈伸肌变化情况,并分析颈长肌和颈伸肌的术后变化与ACDF手术疗效的相关性。方法以该科2016年6月~2021年6月开展单节段ACDF手术的62例脊髓型颈椎病患者作为研究对象,分别于术前、术后3个月、术后1年和末次随访时,进行VAS评分、mJOA评分和NDI指数等疗效指标评价;同时,采用颈椎MRI T2加权像检查并测量其颈长肌和颈伸肌的横截面积(cross section area,CSA),颈长肌的最长径/最短径比值(ratio of long and short lines,RLS)以及颈长肌和颈伸肌的容积。采用Pearson相关性系数对颈长肌和颈伸肌容积与上述疗效指标进行相关性分析。结果62例患者均成功完成单节段ACDF手术且获访24~30个月、平均25.9个月。与术前相比,患者术后3个月、1年和末次随访时的颈肩痛VAS评分、mJOA评分和NDI指数均显著改善(P<0.05)。末次随访时采用Odom标准评价,优38例,良22例,可2例。与术前相比,所有患者术后3个月、1年和末次随访时的颈长肌CSA和颈长肌容积均显著减少(P<0.05),术后3个月、1年和末次随访时的颈长肌RLS均显著增加(P<0.05);颈伸肌CSA和颈伸肌容积在手术前和术后各时间的变化无显著性差异(P>0.05)。经Pearson相关性分析显示,术后3个月、术后1年和末次随访的颈长肌容积与同时期的VAS评分和NDI指数均呈负相关性(P<0.05),与mJOA评分无明确相关性(P>0.05);而颈伸肌容积与同时期的VAS评分、NDI指数和mJOA评分均无明确的相关性(P>0.05)。结论脊髓型颈椎病患者行ACDF手术后,颈长肌可出现一定程度退变,颈伸肌的退变并不显著。颈长肌的退变可对手术预后产生不利影响。
文摘Objective To explore the efficacy and safety of different surgical approaches of cervical spondylotic myelopathy, and the predictive factors for the outcome of surgery. Methods Clinical data of 68 consecutive patients who underwent surgical treatment from 2003-08-01 to 2006-12-01 were collected. The quantization of the efficacy of operation was made by applying Japanese Orthopedic Association (JOA) scoring system, based on which the recovery rate and satisfaction rate were calculated. In the patients who underwent anterior approach, we compared the recovery rate among the subgroups of different duration of symptoms, age at surgery and the severity of diseases. Any surgery-related complications were also noted. Results 73.5% (50/68) patients underwent anterior approach, with an average recovery rate of (68.21 ± 10.06)% and the satisfaction rate of 88.00%;20.6% patients (14/68) underwent posterior approach, with an average recovery rate of (64.03 ± 7.07)% and the satisfaction rate of 100%. The recovery rate had no significant difference in the two approaches. Only 4 patients (5.9%) underwent anterior and posterior combined approach, and the recovery rate and the satisfaction rate were 65.10% and 100%, respectively. In the group of patients who accepted anterior approach, no significant differences were found in the recovery rates of different age subgroups and different duration of symptom subgroups;the significant differences recovery rates between the moderate and severe subgroups were identified. Minor complications, such as asymptomatic screw misplacement, transient dysphagia/odynophagia, pain related to the donor site and axial syndrome, were observed in a few patients. Conclusion The JOA score can be improved by applying the appropriate approaches and the high recovery and satisfaction rates can be achieved at the same time. The efficacies of anterior and posterior approaches were similar. The complications of surgery were minor. In the patients who underwent anterior approach, the severity of diseases was a predictive factor for the outcome of surgery.
文摘目的:通过三维有限元分析法比较双节段颈椎前路椎间盘切除融合术(anterior cervical discectomy and fusion,ACDF)应用零切迹(zero-profile,ZP)系统与钢板联合融合器(cage-and-plate,CP)固定后颈椎的生物力学变化。方法:采集1例正常成年女性志愿者颈椎C3~C7节段CT扫描数据,建立C3~C7颈椎有限元模型并通过对比前期研究验证模型有效性。ZP固定模型与CP固定模型的手术节段均设定为C4/5与C5/6节段。在C3椎体上方施加轴向压缩负荷73.6N的模拟重力,并逐步施加1.8N·m的转矩,进而模拟屈伸、侧屈及轴向旋转等颈椎运动。测定并比较手术模型融合节段活动度(range of motion,ROM)、邻近节段椎间盘内应力、C5椎体及融合器装置应力。结果:CP固定模型融合节段的ROM在屈伸、侧屈、旋转位均明显小于ZP固定模型;CP固定模型相邻节段(C3/4、C6/7)的椎间盘内应力均远远高于ZP固定模型,两种模型融合节段上方的椎间盘内应力均高于融合节段下方;各工况下,ZP固定模型的C5椎体应力均明显高于CP固定模型,在前屈位时,两模型C5椎体应力最小(ZP固定模型为7.36Mpa,CP固定模型为2.01Mpa);各工况下,ZP固定模型的C4/5、C5/6椎间融合器的应力均大于CP固定模型。结论:相较于CP固定,ACDF术中应用ZP固定对手术节段的限制更小,手术节段ROM更高、微运动更多,融合器及中间椎体应力更大,术后更易发生融合器下沉甚至中间椎体塌陷。