Objective:To observe the mechanism of Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules for neonatal jaundice treatment and offer clinical help to neonatal jaundice treatment. Met...Objective:To observe the mechanism of Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules for neonatal jaundice treatment and offer clinical help to neonatal jaundice treatment. Methods:80 children with neonatal jaundice were selected and randomly divided into groups:the observation group (40 children) and the control group (40 children). The patient in the control group were treated with blue light and the patients in the observation group were treated with Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules. Biochemical parameters [TBA (total bile acid), TSB (serum total bilirubin), DB (Direct bilirubin) and TCB (Percutaneous jaundice index)], nerve factor [NSE (neuronspecific enolase), Aβ(βamyloid protein) and S100B (Astrocyte derived protein)] and myocardial enzyme spectrum [LDH (lactate dehydrogenase), CK (creatine kinase) and CK-MB (isoenzymes of creatine kinase)], liver function [ALT (Alanine aminotransferase) and AST (glutamic-oxalacetic transaminase)] and renal function (BUN and Cr) were detected and analyzed before and after treatment. Results:The comparison of Biochemical parameters, nerve factor and myocardial enzymes, liver function and renal function in the two groups before treatment were not statistically significant (P>0.05). Biochemical parameters (TBA, TSB, TCB and DB), nerve factor (NSE, Aβand S100B) and myocardial enzyme spectrum (LDH, CK and CK-MB), liver function (ALT and AST) and renal function [BUN (urea nitrogen) and Cr (creatinine)] in both groups after treatment significantly decreased compared with that before treatment. The changes were statistically significant (P<0.05). Biochemical parameters (TBA, TSB, TCB and DB), nerve factor (NSE, Aβand S100B) and myocardial enzyme spectrum (LDH, CK and CK-MB), liver function (ALT and AST) and renal function (BUN and Cr) in observation group after treatment decreased more significantly compared with that in control group. The difference between two groups was considered to be statistically significant (P<0.05). Conclusions:Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules could regulate the Biochemical parameters, protect nerve function and cardiac muscle cells and improve liver and kidney function in newborns with jaundice. So it has a very important clinical significance of the treatment to neonatal jaundice.展开更多
Objective: To study the effect of triple viable capsule combined with antibiotic therapy on the inflammatory factors and intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis. Methods:...Objective: To study the effect of triple viable capsule combined with antibiotic therapy on the inflammatory factors and intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis. Methods: Patients with cirrhosis combined with spontaneous bacterial peritonitis who were treated in Traditional Chinese Medicine Hospital of Shehong County between March 2015 and October 2017 were selected and randomly divided into the observation group who accepted triple viable capsule combined with antibiotic therapy and the control group who accepted conventional symptomatic treatment. The levels of inflammatory factors and intestinal mucosal barrier markers in serum as well as the number of intestinal flora in feces were detected before treatment and 2 weeks after treatment. Results: Compared with those of same group before treatment, PCT, CRP, sTREM-1, MCP-1, TNF-α, IFN-γ, DAO, D-lactic acid, LPS, Occludin and ZO-1 levels in serum as well as the number of enterobacter and enterococcus in feces of both groups of patients were lower whereas the number of bifidobacterium, lactobacillus and clostridium leptum were higher after treatment, and PCT, CRP, sTREM-1, MCP-1, TNF-α, IFN-γ, DAO, D-lactic acid, LPS, Occludin and ZO-1 levels in serum as well as the number of enterobacter and enterococcus in feces of observation group after treatment were lower than those of control group whereas the number of bifidobacterium, lactobacillus and clostridium leptum were higher than those of control group. Conclusion: Triple viable capsule combined with antibiotic therapy can inhibit the secretion of inflammatory cytokines and improve the intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis.展开更多
文摘Objective:To observe the mechanism of Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules for neonatal jaundice treatment and offer clinical help to neonatal jaundice treatment. Methods:80 children with neonatal jaundice were selected and randomly divided into groups:the observation group (40 children) and the control group (40 children). The patient in the control group were treated with blue light and the patients in the observation group were treated with Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules. Biochemical parameters [TBA (total bile acid), TSB (serum total bilirubin), DB (Direct bilirubin) and TCB (Percutaneous jaundice index)], nerve factor [NSE (neuronspecific enolase), Aβ(βamyloid protein) and S100B (Astrocyte derived protein)] and myocardial enzyme spectrum [LDH (lactate dehydrogenase), CK (creatine kinase) and CK-MB (isoenzymes of creatine kinase)], liver function [ALT (Alanine aminotransferase) and AST (glutamic-oxalacetic transaminase)] and renal function (BUN and Cr) were detected and analyzed before and after treatment. Results:The comparison of Biochemical parameters, nerve factor and myocardial enzymes, liver function and renal function in the two groups before treatment were not statistically significant (P>0.05). Biochemical parameters (TBA, TSB, TCB and DB), nerve factor (NSE, Aβand S100B) and myocardial enzyme spectrum (LDH, CK and CK-MB), liver function (ALT and AST) and renal function [BUN (urea nitrogen) and Cr (creatinine)] in both groups after treatment significantly decreased compared with that before treatment. The changes were statistically significant (P<0.05). Biochemical parameters (TBA, TSB, TCB and DB), nerve factor (NSE, Aβand S100B) and myocardial enzyme spectrum (LDH, CK and CK-MB), liver function (ALT and AST) and renal function (BUN and Cr) in observation group after treatment decreased more significantly compared with that in control group. The difference between two groups was considered to be statistically significant (P<0.05). Conclusions:Yinzhihuang granules, Blue light irradiation combined with Bifid Triple Viable Capsules could regulate the Biochemical parameters, protect nerve function and cardiac muscle cells and improve liver and kidney function in newborns with jaundice. So it has a very important clinical significance of the treatment to neonatal jaundice.
文摘Objective: To study the effect of triple viable capsule combined with antibiotic therapy on the inflammatory factors and intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis. Methods: Patients with cirrhosis combined with spontaneous bacterial peritonitis who were treated in Traditional Chinese Medicine Hospital of Shehong County between March 2015 and October 2017 were selected and randomly divided into the observation group who accepted triple viable capsule combined with antibiotic therapy and the control group who accepted conventional symptomatic treatment. The levels of inflammatory factors and intestinal mucosal barrier markers in serum as well as the number of intestinal flora in feces were detected before treatment and 2 weeks after treatment. Results: Compared with those of same group before treatment, PCT, CRP, sTREM-1, MCP-1, TNF-α, IFN-γ, DAO, D-lactic acid, LPS, Occludin and ZO-1 levels in serum as well as the number of enterobacter and enterococcus in feces of both groups of patients were lower whereas the number of bifidobacterium, lactobacillus and clostridium leptum were higher after treatment, and PCT, CRP, sTREM-1, MCP-1, TNF-α, IFN-γ, DAO, D-lactic acid, LPS, Occludin and ZO-1 levels in serum as well as the number of enterobacter and enterococcus in feces of observation group after treatment were lower than those of control group whereas the number of bifidobacterium, lactobacillus and clostridium leptum were higher than those of control group. Conclusion: Triple viable capsule combined with antibiotic therapy can inhibit the secretion of inflammatory cytokines and improve the intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis.
