Dimericbiscognienynes B and C(1 and 2), two new diisoprenyl-cyclohexene-type meroterpenoid dimers,were isolated from Biscogniauxia sp. 71-10-1-1. Their structures, including the absolute configurations,were determined...Dimericbiscognienynes B and C(1 and 2), two new diisoprenyl-cyclohexene-type meroterpenoid dimers,were isolated from Biscogniauxia sp. 71-10-1-1. Their structures, including the absolute configurations,were determined by spectroscopic analyses and ECD experiments. Meroterpenoids are special natural products that originate from mixed terpenoid-nonterpenoid pathway. As a member of meroterpenoid family, diisoprenyl-cyclohexene/ane-type meroterpenoids composed of two isoprenyl chains(C5 unit)and a cyclohexene/ane moiety(C6 unit), featuring diverse skeleton structures with wide range of bioactivities. In these reported diisoprenyl-cyclohexene/ane-type meroterpenoids, only three dimers were identified. The discovery of the two new dimers added members of this rare class of meroterpenoids.展开更多
基金financially supported by grants from the National Natural Science Foundation of China (No. 3171101305)Chang Jiang Scholars Program (Hao Gao, 2017)+4 种基金the Ministry of Education of China, the Guangdong Natural Science Funds for Distinguished Young Scholar (No. 2017A03036027)Guangdong Special Support Program (No. 2016TX03R28)Guangdong Province Universitiesand Colleges Pearl River Scholar Funded Scheme (Hao Gao, 2014)Pearl River Nova Program of Guangzhou (No. 201610010021)K. C. Wong Education Foundation (Hao Gao, 2016)
文摘Dimericbiscognienynes B and C(1 and 2), two new diisoprenyl-cyclohexene-type meroterpenoid dimers,were isolated from Biscogniauxia sp. 71-10-1-1. Their structures, including the absolute configurations,were determined by spectroscopic analyses and ECD experiments. Meroterpenoids are special natural products that originate from mixed terpenoid-nonterpenoid pathway. As a member of meroterpenoid family, diisoprenyl-cyclohexene/ane-type meroterpenoids composed of two isoprenyl chains(C5 unit)and a cyclohexene/ane moiety(C6 unit), featuring diverse skeleton structures with wide range of bioactivities. In these reported diisoprenyl-cyclohexene/ane-type meroterpenoids, only three dimers were identified. The discovery of the two new dimers added members of this rare class of meroterpenoids.
