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Obstetric Fistula: Epidemiological, Social and Therapeutic Aspects: Prospective Study of 196 Patients Admitted to the ZINDER Mother and Child Health Centre (CSME)
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作者 Maazou Halidou Ousmane Manzo +7 位作者 Zalika Lankoande Abdoulaye Kodo Harissou Adamou Oumarou Habou Abdoulaye Idrissa Tassiou Ibrahim Nafiou Idi Soumana Amadou 《Open Journal of Urology》 2024年第2期95-103,共9页
Introduction: Obstetric fistula (OF) is an abnormal communication between the genital and urinary tracts and/or associated with a recto-vaginal communication resulting from prolonged dystocic delivery. It is a frequen... Introduction: Obstetric fistula (OF) is an abnormal communication between the genital and urinary tracts and/or associated with a recto-vaginal communication resulting from prolonged dystocic delivery. It is a frequent pathology in underdeveloped countries. In Zinder no study has been carried out on obstetric fistula. The aim of this study was to evaluate the epidemiological, social impact and therapeutic aspects of obstetric fistula at the CSME of Zinder. Patient and Method: This was a descriptive cross-sectional study of obstetric fistula care at CSME during the period of (January 2018 to June 2020). Results: A total of 196 cases were collected over 30 months. This represents an annual incidence of 78.4 fistulas. The median age of the patients was 18.63 years, and more than 65% were over 20 years old. One hundred and ninety-one patients (97.45%) did not attend school, and 56.12% (n = 110) lived in polygamous households. One hundred and fifty-one women (n = 151), 77.04% had full assistance from their husband during the first four (4) months of the pathology. Twenty-four (12.24%) had been notified of repudiation. Obstetrical risk of dystocia was found in 39.79% (n = 78) of the patients, of whom 24.49% (n = 48) had a focused antenatal consultation (CPNR). The labour lasted more than 24 hours in 100%. The majority of women are multiparous and 60% had at least 2 pregnancies. vesicovaginal fistula is the main pathological type with 86.23%. Fistulas were closed in 83.16% and 68.87% exited without urine loss. Conclusion: Obstetric fistula is a devastating disease affecting girls and young women in Niger, as in other countries in Africa and Asia. It is a major concern worldwide and is a social tragedy because it is disabling and depressing. 展开更多
关键词 Obstetric Fistula EPIDEMIOLOGY csme Zinder
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Analysis of Maternal Mortality at the Maradi Maternal and Child Health Center/Niger: About 379 Cases
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作者 Amadou Issa Abdou Oumara Maina +6 位作者 Lankoandé Salifou Zélika Tamo Kailou Azize Moussa Boukari Soumana Diaouga Hamadou Oumarou Garba Souleymane Hassane Rabiatou Nayama Madi 《Open Journal of Obstetrics and Gynecology》 2024年第9期1529-1539,共11页
Introduction: Pregnancy, childbirth, and their consequences continue to be the leading cause of death, illness, and disability among women of reproductive age in developing countries. In Niger, maternal deaths account... Introduction: Pregnancy, childbirth, and their consequences continue to be the leading cause of death, illness, and disability among women of reproductive age in developing countries. In Niger, maternal deaths account for about 39% of all deaths of women aged 15-49. Our aim was to identify the factors linked to maternal mortality in order to contribute to its reduction. Method: this is a descriptive retrospective study of 379 cases of maternal deaths collected at the Maradi CSME from January 1, 2018, to December 31, 2021.Results: Our study’s maternal mortality ratio is 2645.72 per 100,000 live births. The mean age of our patients was 27.46 years, with extremes ranging from 15 to 47 years. The 20-24 age group was the most represented, with 88 cases (23.2%). Housewives were 361 (95.3%), and 334 patients (88.1%) were uneducated. There were 261 of them from rural areas, i.e. 69%. The mean parity in our study was 3.46, with extremes ranging from 0 to 15. Multiparous patients 117 cases (30.9%) represented the most significant proportion. Only 42 patients (11.08%) had performed four or more antenatal consultations. Direct obstetric causes accounted for 56.73% of the causes of maternal death. Anemia was the leading cause of maternal death (31.66%). Nearly half of the patients had died before 24 hours after admission, i.e. 49.86%. Conclusion: Maternal mortality remains a significant challenge for developing countries, given its magnitude and timid decline. The fight to reduce maternal mortality must be the priority of our countries’ health policies. 展开更多
关键词 Maternal Mortality csme Maradi ANEMIA
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四黄止痢复方醇提物(CSME)抗禽大肠杆菌的作用机制 被引量:3
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作者 孙嘉一 蒋红 +6 位作者 马巍 刘全 董国英 刘悦 曹艳子 周铁忠 王宏军 《中国兽医学报》 CAS CSCD 北大核心 2019年第3期493-496,506,共5页
为了探讨四黄止痢复方醇提物(CSME)对禽大肠杆菌的抗菌机制。采用微孔-平板法检测其对禽大肠杆菌的最小抑菌浓度(MIC);用吸光光度法检测其对细菌生长曲线、细胞膜通透性和能量代谢活力的影响;荧光定量PCR法检测其对禽大肠杆菌4种主要毒... 为了探讨四黄止痢复方醇提物(CSME)对禽大肠杆菌的抗菌机制。采用微孔-平板法检测其对禽大肠杆菌的最小抑菌浓度(MIC);用吸光光度法检测其对细菌生长曲线、细胞膜通透性和能量代谢活力的影响;荧光定量PCR法检测其对禽大肠杆菌4种主要毒力因子(tsh、iss、ibeA和fimC)表达的影响。结果显示,CSME对禽大肠杆菌(CVCC251)的MIC为125 g/L,1/2MIC就能显著抑制细菌生长,破坏细菌细胞膜结构,使核酸、蛋白质外泄,并抑制了琥珀酸脱氢酶(SDH)和苹果酸脱氢酶(MDH)的活性;1/8MIC能显著抑制了禽大肠杆菌tsh、iss和fimC毒力因子基因的表达(P<0.01)。结果表明,CSME可以通过破坏细菌细胞膜结构、造成细菌能量代谢紊乱、抑制毒力基因表达发挥抗菌活性。 展开更多
关键词 四黄止痢复方 提取物 抗菌机制 禽大肠杆菌
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Abdominal Pregnancy with Hemorrhagic Placenta: About a Case at the Mother and Child Health Center of Zinder
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作者 Souleymane Oumarou Garba Maina Oumara +5 位作者 Zélika Salifou Lankoande Issa Abdou Amadou Hassane Laoul Nabara Ibrahim H. Adamou Madi Nayama 《Surgical Science》 2023年第2期84-89,共6页
Background: In developing countries maternal mortality and morbidity are most often due to the late to consult, poverty and ignorance. Added to this is, the under-medicalization of the health system. The objective of ... Background: In developing countries maternal mortality and morbidity are most often due to the late to consult, poverty and ignorance. Added to this is, the under-medicalization of the health system. The objective of study is to report a case of late consultation and its consequences and make recommendations to improve: case of abdominal pregnancy with hemorrhagic placenta at the Health and Mother Center (CSME) in Zinder/Niger. Clinical Observation: We describe a case of abdominal pregnancy with hemorrhagic placenta in a 24-year-old woman, without profession, resident in the city of Zinder with a low economic level, consulted for abdomino-pelvic pain. She had a notion of amenorrhea for 5 months without any consultation made. She was pale, feverish and had abdominal pain. Ultrasound revealed a 23-week-old fetus and an empty uterus. The diagnosis was abdominal pregnancy. A laparotomy was performed and a The morbidity was hysterectomy and anemia. The postoperative period course was complicated with anemia. The patient was cured on the 9th day with a good vital prognosis. Conclusion: Abdominal pregnancy occurred in a patient who presented a risk factor. Ultrasound was the key diagnostic test. Surgery was the treatment of choice and the prognosis depends on the earliness of the consultation. Community awareness and early consultation with health services can improve the prognosis of abdominal pregnancy. 展开更多
关键词 Abdominal Pregnancy Hemorrhagic Placenta csme Zinder
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马桑水提取物对大鼠深Ⅱ度烧伤创面微循环和氧化应激的影响 被引量:18
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作者 胡泽华 余昭芬 +2 位作者 黄谨 陈薛妃 黄德斌 《中国应用生理学杂志》 CAS CSCD 北大核心 2018年第1期50-56,I0003,共8页
目的:探索马桑水提取物(CSME)对大鼠深Ⅱ度烧伤创面微循环和氧化应激的影响。方法:随机将180只SD大鼠分成6组(n=30):对照组(生理盐水组,NS)、凡士林组(WPL)、磺胺嘧啶银组(SSD)、马桑提取物组(低剂量组(CSME-L)、中剂量组(CSME-M)和高... 目的:探索马桑水提取物(CSME)对大鼠深Ⅱ度烧伤创面微循环和氧化应激的影响。方法:随机将180只SD大鼠分成6组(n=30):对照组(生理盐水组,NS)、凡士林组(WPL)、磺胺嘧啶银组(SSD)、马桑提取物组(低剂量组(CSME-L)、中剂量组(CSME-M)和高剂量组(CSME-H)。麻醉后用烫伤仪烫伤脱毛区(病理结果证实深Ⅱ度烫伤),伤后创面分别涂擦NS、WPL、SSD和不同浓度的CSME烧伤软膏。于伤后48 h、7 d、14 d、21 d计算创面愈合率(HR),检测创面微血管(MVD)、创面组织含水量(TM)、血管内皮生长因子(VEGF)、丙二醛(MDA)、超氧化物歧化酶(SOD)、羟脯氨酸(HYP),进行创面组织学观察。结果:CSME各组的HR呈剂量依赖性大于NS和WPL(P<0.05);在21 d,其创面组织血管管径、数量、分布及TM呈剂量依赖性少于其他各组(P<0.05),伤后7 d、14 d,CSME各组呈现剂量依赖性高于NS、WPL和SSD(P<0.05),而伤后21 d呈剂量依赖性低于NS、WPL和SSD(P<0.05);CSME的SOD活性、HYP、NO和ET含量呈剂量依赖性高于其他各组(P<0.05),而MDA活性呈剂量依赖性弱于其他各组(P<0.05),CSME呈剂量依赖性缩短创面修复时间,瘢痕少于其他各组。结论:CSME具有早期减轻烧伤创面组织水肿、促进创面收缩、加快创面结痂以及促进肉芽组织增生,有利于创面愈合;后期则抑制创面肉芽组织增生,防止瘢痕过度增生。其机制与创面微循环、氧化应激、NO和VEGF的调控有关。 展开更多
关键词 马桑水提取物(csme) 烧伤创面 微循环 氧化应激 创面愈合 大鼠
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EPA网络芯片验证与测试
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作者 陈鹏 冯冬芹 《计算机工程》 CAS CSCD 2012年第8期264-267,共4页
提出一种EPA网络芯片的验证方法。介绍EPA网络芯片的功能和结构,设计基于虚拟设备的EPA网络环境,从验证网络通信接口和调度正确性的角度,将设计的EPA网络芯片接入到已有EPA网络中进行测试。测试结果表明,该仿真系统的同步精度在1μs以内... 提出一种EPA网络芯片的验证方法。介绍EPA网络芯片的功能和结构,设计基于虚拟设备的EPA网络环境,从验证网络通信接口和调度正确性的角度,将设计的EPA网络芯片接入到已有EPA网络中进行测试。测试结果表明,该仿真系统的同步精度在1μs以内,能满足使用需求,且验证了现场可编程逻辑门阵列作为从时钟程序的稳定性。 展开更多
关键词 EPA协议 仿真系统 通信调度管理实体 时钟同步 网络测试平台
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地球的礼物
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作者 奕欢 《钟表》 2009年第2期59-59,共1页
硅,大自然的诗意结晶体,就像是宇宙赠予地球的礼物散落在最广泛的地方。越来越多的品牌依靠强大的设计能力和制造能力,不断挑战冶金和制造工艺的极限,将这个地球的礼物不断发扬光大。
关键词 钟表 csme 电子技术 制造能力 设计能力 制造工艺
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基于EPA的分布式控制系统研究与设计
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作者 周宏伟 陈布亮 《指挥控制与仿真》 2009年第5期81-85,共5页
在模拟信号控制的数控系统基础上,设计了基于EPA标准的分布式控制系统;介绍了EPA标准,研究了确定性通信调度机制和精确时钟同步协议的应用这两个关键技术,设计了控制系统中通信模块和嵌入式转接电路板,并对试验结果进行了演示。结果表明... 在模拟信号控制的数控系统基础上,设计了基于EPA标准的分布式控制系统;介绍了EPA标准,研究了确定性通信调度机制和精确时钟同步协议的应用这两个关键技术,设计了控制系统中通信模块和嵌入式转接电路板,并对试验结果进行了演示。结果表明,该系统运行稳定,各项性能满足应用需求,对军用控制系统的研究提供了较好的借鉴经验。 展开更多
关键词 工业自动化以太网 控制系统 通信调度管理实体 精确时钟同步协议
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