To observe the clinical efficacy of nape cluster acupuncture in treating migraine. Methods： Fifty patients with confirmed diagnosis of migraine were intervened by using nape cluster acupuncture, and were evaluated at...To observe the clinical efficacy of nape cluster acupuncture in treating migraine. Methods： Fifty patients with confirmed diagnosis of migraine were intervened by using nape cluster acupuncture, and were evaluated at the outset and after 2-month treatment by the short-form of McGill pain questionnaire （SP-MPQ） and self-rating depression scale （SDS）. Results： After treatment, the number of positive words, sensory pain rating index （S-PRI）, affective pain rating index （A-PRI）, total pain rating index （T-PRI）, visual analogue scale （VAS）, and present pain intensity （PPI） were significantly changed （P〈0.01）; the SDS score was （56.42＋8.12） points before treatment versus （41.08＋5.73） points after treatment, and the difference was statistically significant （P〈0.01）. The total effective rate was 86.0%; the therapeutic efficacy of the patients with a shorter disease duration was superior to that of the patients with a longer one （P〈0.05）; the efficacy of mild-moderate migraine was superior to that of severe one （P〈0.01）; the total effective rate of patients without depression was higher than that with depression, but without a significant difference in comparing the therapeutic efficacy （P〈0.05）. Conclusion： Nape cluster acupuncture is effective in treating migraine, significantly improving headache and depression.展开更多
Objective:Cluster needling at scalp acupoints has showed satisfying effects with acute cerebral ischemia in clinic whereas the mechanisms are not yet clear completely.This study investigated the influence of cluster n...Objective:Cluster needling at scalp acupoints has showed satisfying effects with acute cerebral ischemia in clinic whereas the mechanisms are not yet clear completely.This study investigated the influence of cluster needling at scalp acupoints on neurological function,as well as on neurofilament protein 200(NF200)and signal transducer and activator of transcription 3(STAT3)expression,in rats with acute cerebral ischemia.Methods:Fifty-four Sprague-Dawley rats were randomly assigned in equal numbers to the false operation(group F),model(group M),or cluster needling scalp acupuncture(group C)groups.Each group was divided into three subgroups,of six rats each,by acupuncture treatment time(24 h,7 days,and 14 days).The rat local cerebral ischemia model was prepared using a modified suture occlusion method.Group C rats were treated by cluster needling scalp acupuncture,while groups F and M did not receive acupuncture treatment.Neurological effects were evaluated using the Longa score.NF200 and STAT3 expression were measured by western blotting.Results:At 24 h,there were no statistical difference between group C and group M in nerve function(P>.05).On days 7 and 14,nerve function scores in group C were significantly lower than that in group M(respectively were P<.05 and P<.01).In addition,on days 14,expression of NF200 was significantly higher in group C compared with group M(P<.05).Compared with group M,STAT3 expression was also higher in group C on days 7 and 14,although these differences were not statistically significant(both P>.05).Conclusion:Cluster needling scalp acupuncture were efficient in improving nerve function scores in rats with cerebral ischemia,and promoting the recovery of motor function.These improvements were associated with increases in NF200 and STAT3 expression.展开更多
基金supported by Shanghai Leading Academic Discipline Project~~
文摘To observe the clinical efficacy of nape cluster acupuncture in treating migraine. Methods： Fifty patients with confirmed diagnosis of migraine were intervened by using nape cluster acupuncture, and were evaluated at the outset and after 2-month treatment by the short-form of McGill pain questionnaire （SP-MPQ） and self-rating depression scale （SDS）. Results： After treatment, the number of positive words, sensory pain rating index （S-PRI）, affective pain rating index （A-PRI）, total pain rating index （T-PRI）, visual analogue scale （VAS）, and present pain intensity （PPI） were significantly changed （P〈0.01）; the SDS score was （56.42＋8.12） points before treatment versus （41.08＋5.73） points after treatment, and the difference was statistically significant （P〈0.01）. The total effective rate was 86.0%; the therapeutic efficacy of the patients with a shorter disease duration was superior to that of the patients with a longer one （P〈0.05）; the efficacy of mild-moderate migraine was superior to that of severe one （P〈0.01）; the total effective rate of patients without depression was higher than that with depression, but without a significant difference in comparing the therapeutic efficacy （P〈0.05）. Conclusion： Nape cluster acupuncture is effective in treating migraine, significantly improving headache and depression.
基金This study was supported by grants from the National Natural Science Foundation of China(grant No.81473775).
文摘Objective:Cluster needling at scalp acupoints has showed satisfying effects with acute cerebral ischemia in clinic whereas the mechanisms are not yet clear completely.This study investigated the influence of cluster needling at scalp acupoints on neurological function,as well as on neurofilament protein 200(NF200)and signal transducer and activator of transcription 3(STAT3)expression,in rats with acute cerebral ischemia.Methods:Fifty-four Sprague-Dawley rats were randomly assigned in equal numbers to the false operation(group F),model(group M),or cluster needling scalp acupuncture(group C)groups.Each group was divided into three subgroups,of six rats each,by acupuncture treatment time(24 h,7 days,and 14 days).The rat local cerebral ischemia model was prepared using a modified suture occlusion method.Group C rats were treated by cluster needling scalp acupuncture,while groups F and M did not receive acupuncture treatment.Neurological effects were evaluated using the Longa score.NF200 and STAT3 expression were measured by western blotting.Results:At 24 h,there were no statistical difference between group C and group M in nerve function(P>.05).On days 7 and 14,nerve function scores in group C were significantly lower than that in group M(respectively were P<.05 and P<.01).In addition,on days 14,expression of NF200 was significantly higher in group C compared with group M(P<.05).Compared with group M,STAT3 expression was also higher in group C on days 7 and 14,although these differences were not statistically significant(both P>.05).Conclusion:Cluster needling scalp acupuncture were efficient in improving nerve function scores in rats with cerebral ischemia,and promoting the recovery of motor function.These improvements were associated with increases in NF200 and STAT3 expression.
