Posterior cortical atrophy(PCA) is a rare neurodegene-rative condition characterized by progressive visual-perceptual deficits. Although the neurocognitive profile of PCA is a growing and relatively well-established f...Posterior cortical atrophy(PCA) is a rare neurodegene-rative condition characterized by progressive visual-perceptual deficits. Although the neurocognitive profile of PCA is a growing and relatively well-established field, non-pharmacological care remains understudied and to be widely established in clinical practice. In the present work we review the available literature on non-pharmacological approaches for PCA, such as cognitive rehabilitation including individual cognitive exercises and compensatory techniques to improve autonomy in daily life, and psycho-education aiming to inform people with PCA about the nature of their visual deficits and limits of cognitive rehabilitation. The reviewed studies represented a total of 7 patients. There is a scarcity of the number of studies, and mostly consisting of case studies. Results suggest non-pharmacological intervention to be a potentially beneficial approach for the partial compensation of deficits, improvement of daily functionality and improvement of quality of life. Clinical implications and future directions are also highlighted for the advancement of the field, in order to clarify the possible role of non-pharmacological interventions, and its extent, in PCA.展开更多
当我们临床医师似乎已经学会了应用各种最新权威指南一致推荐的有理有据的食品药品监督管理局（Food and Drug Administration,FDA）批准的阿尔茨海默病（Alzheimer’s disease,AD）一线治疗药物乙酰胆碱酯酶抑制剂（acetylcholinestera...当我们临床医师似乎已经学会了应用各种最新权威指南一致推荐的有理有据的食品药品监督管理局（Food and Drug Administration,FDA）批准的阿尔茨海默病（Alzheimer’s disease,AD）一线治疗药物乙酰胆碱酯酶抑制剂（acetylcholinesterase inhibitors,ACh EI）及谷氨酸NMDA受体（N-methyl-D-aspartic acid receptor）拮抗剂治疗痴呆时,展开更多
文摘Posterior cortical atrophy(PCA) is a rare neurodegene-rative condition characterized by progressive visual-perceptual deficits. Although the neurocognitive profile of PCA is a growing and relatively well-established field, non-pharmacological care remains understudied and to be widely established in clinical practice. In the present work we review the available literature on non-pharmacological approaches for PCA, such as cognitive rehabilitation including individual cognitive exercises and compensatory techniques to improve autonomy in daily life, and psycho-education aiming to inform people with PCA about the nature of their visual deficits and limits of cognitive rehabilitation. The reviewed studies represented a total of 7 patients. There is a scarcity of the number of studies, and mostly consisting of case studies. Results suggest non-pharmacological intervention to be a potentially beneficial approach for the partial compensation of deficits, improvement of daily functionality and improvement of quality of life. Clinical implications and future directions are also highlighted for the advancement of the field, in order to clarify the possible role of non-pharmacological interventions, and its extent, in PCA.
文摘当我们临床医师似乎已经学会了应用各种最新权威指南一致推荐的有理有据的食品药品监督管理局（Food and Drug Administration,FDA）批准的阿尔茨海默病（Alzheimer’s disease,AD）一线治疗药物乙酰胆碱酯酶抑制剂（acetylcholinesterase inhibitors,ACh EI）及谷氨酸NMDA受体（N-methyl-D-aspartic acid receptor）拮抗剂治疗痴呆时,
