Finding binary sequences with Large SHG ratios is very important in the field of ultrafast science, biomedical optics, high-resolution microscopy and label-free imaging. In this paper, we have demonstrated the relatio...Finding binary sequences with Large SHG ratios is very important in the field of ultrafast science, biomedical optics, high-resolution microscopy and label-free imaging. In this paper, we have demonstrated the relation between the SHG contrast ratio and the traditional Merit Factor values. And in the light from known results in Merit Factor Problems, we have shown that Legendre Sequences or Jacobi Sequences, are still the best candidates to obtain binary sequences with large SHG contrast ratios. The authors also discussed the SHG behaviors on some sequences obtained from cyclotomic classes over the finite field GF (2l) .展开更多
Colorless‐to‐black switching has attracted widespread attention for smart windows and multifunctional displays because they are more useful to control solar energy.However,it still remains a challenge owing to the t...Colorless‐to‐black switching has attracted widespread attention for smart windows and multifunctional displays because they are more useful to control solar energy.However,it still remains a challenge owing to the tremendous difficulties in the design of completely reverse absorptions in transmissive and colored states.Herein,we report on an electrochemical device that can switch between colorless and black by using the electrochemical process of hybrid organic–inorganic perovskite MAPbBr_(3),which shows a high integrated contrast ratio of up to 73%from 400 to 800 nm.The perovskite solution can be used as the active layer to assemble the device,showing superior transmittance over the entire visible region in neutral states.By applying an appropriate voltage,the device undergoes reversible switching between colorless and black,which is attributed to the formation of lead and Br_(2)in the redox reaction induced by the electron transfer process in MAPbBr_(3).In addition,the contrast ratio can be modulated over the entire visible region by changing the concentration and the applied voltage.These results contribute toward gaining an insightful understanding of the electrochemical process of perovskites and greatly promoting the development of switchable devices.展开更多
BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory in...BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory indices and left atrial appendage thrombus(LAAT)or dense spontaneous echo contrast(SEC)are limited.AIM To explore the value of inflammatory indices for predicting the presence of LAAT or dense SEC in nonvalvular AF patients.METHODS A total of 406 patients with nonvalvular AF who underwent transesophageal echocardiography were included and divided into two groups based on the presence(study group)or absence(control group)of LAAT or dense SEC.Inflammatory indices,including the neutrophil-to-lymphocyte ratio(NLR),platelet–tolymphocyte ratio(PLR),and lymphocyte-to-monocyte ratio(LMR),were calculated from complete blood analysis.The associations of inflammatory indices RESULTS LAAT and dense SEC were detected in 11(2.7%)and 42(10.3%)patients,respectively.The PLR only showed an association with LAAT/dense SEC in the univariate model.Elevated NLR(odds ratio[OR]=1.48,95%confidence interval[CI]:1.11-1.98,P=0.007)and reduced LMR(OR=0.59,95%CI:0.41-0.83,P=0.003)were found to be independent risk factors for the presence of LAAT/dense SEC.The areas under the NLR and LMR curves for predicting LAAT/dense SEC were 0.73(95%CI:0.66-0.80,P<0.001)and 0.73(95%CI:0.65-0.81,P<0.001),respectively,while the cutoff values were 2.8(sensitivity:69.8%;specificity:64.0%)and 2.4(sensitivity:71.7%;specificity:60.6%),respectively.CONCLUSION Increased NLR and decreased LMR may predict LAAT/dense SEC in patients with nonvalvular AF.展开更多
Objective To quantitatively compare and determine the best pancreatic tumor contrast to noise ratio (CNR) in different dual-energy derived datasets. Methods In this retrospective, single center study, 16 patients (9 m...Objective To quantitatively compare and determine the best pancreatic tumor contrast to noise ratio (CNR) in different dual-energy derived datasets. Methods In this retrospective, single center study, 16 patients (9 male, 7 female, average age 59.4±13.2 years) with pathologically diagnosed pancreatic cancer were enrolled. All patients received an abdominal scan using a dual source CT scanner 7 to 31 days before biopsy or surgery. After injection of iodine contrast agent, arterial and pancreatic parenchyma phase were scanned consequently, using a dual-energy scan mode (100 kVp/230 mAs and Sn 140 kVp/178 mAs) in the pancreatic parenchyma phase. A series of derived dual-energy datasets were evaluated including non-liner blending (non-linear blending width 0-500 HU; blending center -500 to 500 HU), mono-energetic (40-190 keV), 100 kVp and 140 kVp. On each datasets, mean CT values of the pancreatic parenchyma and tumor, as well as standard deviation CT values of subcutaneous fat and psoas muscle were measured. Regions of interest of cutaneous fat and major psoas muscle of 100 kVp and 140 kVp images were calculated. Best CNR of subcutaneous fat (CNR F ) and CNR of the major psoas muscle (CNR M ) of non-liner blending and mono-energetic datasets were calculated with the optimal mono-energetic keV setting and the optimal blending center/width setting for the best CNR. One Way ANOVA test was used for comparison of best CNR between different dual-energy derived datasets. Results The best CNR F (4.48±1.29) was obtained from the non-liner blending datasets at blending center -16.6±103.9 HU and blending width 12.3±10.6 HU. The best CNR F (3.28±0.97) was obtained from the mono-energetic datasets at 73.3±4.3 keV. CNR F in the 100 kVp and 140 kVp were 3.02±0.91 and 1.56±0.56 respectively. Using fat as the noise background, all of these images series showed significant differences (P<0.01) except best CNR F of mono-energetic image sets vs. CNR F of 100 kVp image (P=0.460). Similar results were found using muscle as the noise background (mono-energetic image vs. 100 kVp image: P=0.246; mono-energetic image vs. non-liner blending image: P=0.044; others: P<0.01). Conclusion Compared with mono-energetic datasets and low kVp datasets, non-linear blending image at automatically chosen blending width/window provides better tumor to the pancreas CNR, which might be beneficial for better detection of pancreatic tumors.展开更多
We demonstrate a high-quality cross-polarized-wave filter based on spectral phase modulation. Driven by Well- eompressed spectral-phase fully-compensated fundamental laser lmlses, the filter stretches the pulse bandwi...We demonstrate a high-quality cross-polarized-wave filter based on spectral phase modulation. Driven by Well- eompressed spectral-phase fully-compensated fundamental laser lmlses, the filter stretches the pulse bandwidth from 35 nm to 7Ohm with a conversion efficeiency of 20%.展开更多
目的探讨自主研发的16通道高分辨盆腔专用线圈(16C)在3.0 T盆腔MRI中的应用价值。材料和方法前瞻性招募35例行盆腔MRI的患者,分别用16C线圈和32通道的体部线圈(32C)采集相同的轴位和矢状位T2WI序列。比较相同序列图像中第三骶椎、子宫...目的探讨自主研发的16通道高分辨盆腔专用线圈(16C)在3.0 T盆腔MRI中的应用价值。材料和方法前瞻性招募35例行盆腔MRI的患者,分别用16C线圈和32通道的体部线圈(32C)采集相同的轴位和矢状位T2WI序列。比较相同序列图像中第三骶椎、子宫肌层、前列腺外周带、直肠壁和闭孔内肌的信噪比(signal to noise ratio,SNR)及对比噪声比(contrast to noise ratio,CNR)。由两位诊断医师各自对两组图像质量和直肠轴位图像直肠壁分层结构的显示度进行主观评分。结果两组线圈相同序列的T2WI矢状位第三骶椎、子宫肌层、前列腺外周带和轴位闭孔内肌的SNR差异具有统计学意义(P<0.05),矢状位第三骶椎、子宫肌层和轴位直肠壁对肌肉的CNR差异具有统计学意义(P<0.05),16C组高于32C组。两组线圈相同序列的T2WI图像质量主观评价差异具有统计学意义(P<0.05),16C组图像质量更优。在轴位T2WI直肠壁分层结构的显示度评价方面两组图像差异具有统计学意义(P<0.05),16C组更优。结论16C线圈在3.0 T磁共振设备上成像质量更好,更有利于盆腔疾病的诊断。展开更多
目的探讨联合应用AIR-魔毯线圈磁共振成像(MRI)对胸椎结核扫描图像信噪比(signal to noise ratio,SNR)、对比噪声比(contrast to noise ratio,CNR)和脂肪抑制成像效果的价值。方法选取我院80例经手术病理证实为胸椎结核患者,按1:1随机...目的探讨联合应用AIR-魔毯线圈磁共振成像(MRI)对胸椎结核扫描图像信噪比(signal to noise ratio,SNR)、对比噪声比(contrast to noise ratio,CNR)和脂肪抑制成像效果的价值。方法选取我院80例经手术病理证实为胸椎结核患者,按1:1随机分为两组,应用常规线圈(脊柱相控阵线圈,头颈联合线圈)、常规线圈联合AIR魔毯线圈对两组患者分别进行扫描。扫描序列包括胸椎矢状位T_(2)WI,T_(1)WI,T_(2)FLEX,进一步测量、比较SNR,CNR及脂肪抑制效果,分析MRI多序列诊断胸腰椎结核的准确率、特异度和灵敏度。结果常规线圈联合AIR-魔毯线圈扫描组,胸椎矢状位图像的SNR、CNR及压脂效果优于常规线圈组。结论联合应用AIR-魔毯线圈的图像SNR、CNR得到提高,脂肪抑制效果稳定良好。展开更多
目的探讨智能快速磁共振技术(intelligent quick magnetic resonance,IQMR)在冈上肌肌腱损伤中的应用价值。材料与方法对40例冈上肌肌腱损伤患者行肩关节冠状位快速T2WI脂肪抑制(T2WI fat saturation,T2WI-FS)和常规T2WI-FS序列扫描,将...目的探讨智能快速磁共振技术(intelligent quick magnetic resonance,IQMR)在冈上肌肌腱损伤中的应用价值。材料与方法对40例冈上肌肌腱损伤患者行肩关节冠状位快速T2WI脂肪抑制(T2WI fat saturation,T2WI-FS)和常规T2WI-FS序列扫描,将快速T2WI-FS序列的图像传入IQMR后处理系统,自动生成T2WI-FS_(IQMR)图像。由两位放射科医师各自独立对T2WI-FS_(快速)、T2WI-FS_(常规)和T2WI-FS_(IQMR)序列的三组图像的病灶细节清晰度、解剖结构清晰度、整体图像伪影和整体图像质量进行定性评分;根据Zlatkin分型对三组图像的冈上肌肌腱损伤程度进行分级评估,并测量比较三组图像的冈上肌、肱骨头和三角肌的信噪比(signal to noise ratio,SNR)、冈上肌与肱骨头的对比噪声比(contrast to noise ratio,CNR1)和三角肌与肱骨头的对比噪声比(CNR2)。结果T2WI-FS_(IQMR)序列较T2WI-FS_(常规)序列的扫描时间缩短了41%。定性分析:T2WI-FS_(IQMR)图像在病灶细节清晰度、解剖结构清晰度、整体图像伪影和整体图像质量方面的评分均优于T2WI-FS_(快速)和T2WI-FS_(常规)序列图像(P<0.001);三组图像在诊断冈上肌肌腱损伤程度分级上差异无统计学意义(P>0.05)。定量分析:T2WI-FS_(IQMR)组图像的冈上肌、肱骨头和三角肌的SNR、冈上肌与肱骨头的CNR1和三角肌与肱骨头的CNR2均大于T2WI-FS_(快速)组和T2WI-FS_(常规)组(P<0.001)。结论在冈上肌肌腱损伤MRI扫描中,IQMR技术可以明显缩短扫描时间,提高图像质量,值得临床推广应用。展开更多
文摘Finding binary sequences with Large SHG ratios is very important in the field of ultrafast science, biomedical optics, high-resolution microscopy and label-free imaging. In this paper, we have demonstrated the relation between the SHG contrast ratio and the traditional Merit Factor values. And in the light from known results in Merit Factor Problems, we have shown that Legendre Sequences or Jacobi Sequences, are still the best candidates to obtain binary sequences with large SHG contrast ratios. The authors also discussed the SHG behaviors on some sequences obtained from cyclotomic classes over the finite field GF (2l) .
基金Natural Science Foundation of Hebei Province(China),Grant/Award Numbers:B2020203013,B2021203016Science and Technology Project of Hebei Education Department(China),Grant/Award Number:QN2020137+3 种基金Cultivation Project for Basic Research Innovation of Yanshan University(China),Grant/Award Number:2021LGZD015Subsidy for Hebei Key Laboratory of Applied Chemistry after Operation Performance(China),Grant/Award Number:22567616HNatural Science Foundation of Heilongjiang Province(China),Grant/Award Number:LH2022B025Fundamental Research Funds for the Provincial Universities of Heilongjiang Province(China),Grant/Award Number:KYYWF10236190104。
文摘Colorless‐to‐black switching has attracted widespread attention for smart windows and multifunctional displays because they are more useful to control solar energy.However,it still remains a challenge owing to the tremendous difficulties in the design of completely reverse absorptions in transmissive and colored states.Herein,we report on an electrochemical device that can switch between colorless and black by using the electrochemical process of hybrid organic–inorganic perovskite MAPbBr_(3),which shows a high integrated contrast ratio of up to 73%from 400 to 800 nm.The perovskite solution can be used as the active layer to assemble the device,showing superior transmittance over the entire visible region in neutral states.By applying an appropriate voltage,the device undergoes reversible switching between colorless and black,which is attributed to the formation of lead and Br_(2)in the redox reaction induced by the electron transfer process in MAPbBr_(3).In addition,the contrast ratio can be modulated over the entire visible region by changing the concentration and the applied voltage.These results contribute toward gaining an insightful understanding of the electrochemical process of perovskites and greatly promoting the development of switchable devices.
基金Public Welfare Technology Project of Ningbo Science and Technology Bureau,No.2023S140Medical Health Science and Technology Project of Zhejiang Province Health Commission,No.2024KY1518.
文摘BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory indices and left atrial appendage thrombus(LAAT)or dense spontaneous echo contrast(SEC)are limited.AIM To explore the value of inflammatory indices for predicting the presence of LAAT or dense SEC in nonvalvular AF patients.METHODS A total of 406 patients with nonvalvular AF who underwent transesophageal echocardiography were included and divided into two groups based on the presence(study group)or absence(control group)of LAAT or dense SEC.Inflammatory indices,including the neutrophil-to-lymphocyte ratio(NLR),platelet–tolymphocyte ratio(PLR),and lymphocyte-to-monocyte ratio(LMR),were calculated from complete blood analysis.The associations of inflammatory indices RESULTS LAAT and dense SEC were detected in 11(2.7%)and 42(10.3%)patients,respectively.The PLR only showed an association with LAAT/dense SEC in the univariate model.Elevated NLR(odds ratio[OR]=1.48,95%confidence interval[CI]:1.11-1.98,P=0.007)and reduced LMR(OR=0.59,95%CI:0.41-0.83,P=0.003)were found to be independent risk factors for the presence of LAAT/dense SEC.The areas under the NLR and LMR curves for predicting LAAT/dense SEC were 0.73(95%CI:0.66-0.80,P<0.001)and 0.73(95%CI:0.65-0.81,P<0.001),respectively,while the cutoff values were 2.8(sensitivity:69.8%;specificity:64.0%)and 2.4(sensitivity:71.7%;specificity:60.6%),respectively.CONCLUSION Increased NLR and decreased LMR may predict LAAT/dense SEC in patients with nonvalvular AF.
文摘Objective To quantitatively compare and determine the best pancreatic tumor contrast to noise ratio (CNR) in different dual-energy derived datasets. Methods In this retrospective, single center study, 16 patients (9 male, 7 female, average age 59.4±13.2 years) with pathologically diagnosed pancreatic cancer were enrolled. All patients received an abdominal scan using a dual source CT scanner 7 to 31 days before biopsy or surgery. After injection of iodine contrast agent, arterial and pancreatic parenchyma phase were scanned consequently, using a dual-energy scan mode (100 kVp/230 mAs and Sn 140 kVp/178 mAs) in the pancreatic parenchyma phase. A series of derived dual-energy datasets were evaluated including non-liner blending (non-linear blending width 0-500 HU; blending center -500 to 500 HU), mono-energetic (40-190 keV), 100 kVp and 140 kVp. On each datasets, mean CT values of the pancreatic parenchyma and tumor, as well as standard deviation CT values of subcutaneous fat and psoas muscle were measured. Regions of interest of cutaneous fat and major psoas muscle of 100 kVp and 140 kVp images were calculated. Best CNR of subcutaneous fat (CNR F ) and CNR of the major psoas muscle (CNR M ) of non-liner blending and mono-energetic datasets were calculated with the optimal mono-energetic keV setting and the optimal blending center/width setting for the best CNR. One Way ANOVA test was used for comparison of best CNR between different dual-energy derived datasets. Results The best CNR F (4.48±1.29) was obtained from the non-liner blending datasets at blending center -16.6±103.9 HU and blending width 12.3±10.6 HU. The best CNR F (3.28±0.97) was obtained from the mono-energetic datasets at 73.3±4.3 keV. CNR F in the 100 kVp and 140 kVp were 3.02±0.91 and 1.56±0.56 respectively. Using fat as the noise background, all of these images series showed significant differences (P<0.01) except best CNR F of mono-energetic image sets vs. CNR F of 100 kVp image (P=0.460). Similar results were found using muscle as the noise background (mono-energetic image vs. 100 kVp image: P=0.246; mono-energetic image vs. non-liner blending image: P=0.044; others: P<0.01). Conclusion Compared with mono-energetic datasets and low kVp datasets, non-linear blending image at automatically chosen blending width/window provides better tumor to the pancreas CNR, which might be beneficial for better detection of pancreatic tumors.
基金Supported by the National Key Basic Research Program of China under Grant No 2013CB922402the National Natural Science Foundation of China under Grant Nos 61575217 and 11434016+1 种基金the Key Research Program of Frontier Sciences of Chinese Academy of Sciences under Grant Nos KJZD-EW-L11-03 and QYZDJ-SSW-JSC006the Strategic Priority Research Program of Chinese Academy of Sciences under Grant No XDB16030200
文摘We demonstrate a high-quality cross-polarized-wave filter based on spectral phase modulation. Driven by Well- eompressed spectral-phase fully-compensated fundamental laser lmlses, the filter stretches the pulse bandwidth from 35 nm to 7Ohm with a conversion efficeiency of 20%.
文摘目的探讨自主研发的16通道高分辨盆腔专用线圈(16C)在3.0 T盆腔MRI中的应用价值。材料和方法前瞻性招募35例行盆腔MRI的患者,分别用16C线圈和32通道的体部线圈(32C)采集相同的轴位和矢状位T2WI序列。比较相同序列图像中第三骶椎、子宫肌层、前列腺外周带、直肠壁和闭孔内肌的信噪比(signal to noise ratio,SNR)及对比噪声比(contrast to noise ratio,CNR)。由两位诊断医师各自对两组图像质量和直肠轴位图像直肠壁分层结构的显示度进行主观评分。结果两组线圈相同序列的T2WI矢状位第三骶椎、子宫肌层、前列腺外周带和轴位闭孔内肌的SNR差异具有统计学意义(P<0.05),矢状位第三骶椎、子宫肌层和轴位直肠壁对肌肉的CNR差异具有统计学意义(P<0.05),16C组高于32C组。两组线圈相同序列的T2WI图像质量主观评价差异具有统计学意义(P<0.05),16C组图像质量更优。在轴位T2WI直肠壁分层结构的显示度评价方面两组图像差异具有统计学意义(P<0.05),16C组更优。结论16C线圈在3.0 T磁共振设备上成像质量更好,更有利于盆腔疾病的诊断。
文摘目的探讨联合应用AIR-魔毯线圈磁共振成像(MRI)对胸椎结核扫描图像信噪比(signal to noise ratio,SNR)、对比噪声比(contrast to noise ratio,CNR)和脂肪抑制成像效果的价值。方法选取我院80例经手术病理证实为胸椎结核患者,按1:1随机分为两组,应用常规线圈(脊柱相控阵线圈,头颈联合线圈)、常规线圈联合AIR魔毯线圈对两组患者分别进行扫描。扫描序列包括胸椎矢状位T_(2)WI,T_(1)WI,T_(2)FLEX,进一步测量、比较SNR,CNR及脂肪抑制效果,分析MRI多序列诊断胸腰椎结核的准确率、特异度和灵敏度。结果常规线圈联合AIR-魔毯线圈扫描组,胸椎矢状位图像的SNR、CNR及压脂效果优于常规线圈组。结论联合应用AIR-魔毯线圈的图像SNR、CNR得到提高,脂肪抑制效果稳定良好。
文摘目的探讨智能快速磁共振技术(intelligent quick magnetic resonance,IQMR)在冈上肌肌腱损伤中的应用价值。材料与方法对40例冈上肌肌腱损伤患者行肩关节冠状位快速T2WI脂肪抑制(T2WI fat saturation,T2WI-FS)和常规T2WI-FS序列扫描,将快速T2WI-FS序列的图像传入IQMR后处理系统,自动生成T2WI-FS_(IQMR)图像。由两位放射科医师各自独立对T2WI-FS_(快速)、T2WI-FS_(常规)和T2WI-FS_(IQMR)序列的三组图像的病灶细节清晰度、解剖结构清晰度、整体图像伪影和整体图像质量进行定性评分;根据Zlatkin分型对三组图像的冈上肌肌腱损伤程度进行分级评估,并测量比较三组图像的冈上肌、肱骨头和三角肌的信噪比(signal to noise ratio,SNR)、冈上肌与肱骨头的对比噪声比(contrast to noise ratio,CNR1)和三角肌与肱骨头的对比噪声比(CNR2)。结果T2WI-FS_(IQMR)序列较T2WI-FS_(常规)序列的扫描时间缩短了41%。定性分析:T2WI-FS_(IQMR)图像在病灶细节清晰度、解剖结构清晰度、整体图像伪影和整体图像质量方面的评分均优于T2WI-FS_(快速)和T2WI-FS_(常规)序列图像(P<0.001);三组图像在诊断冈上肌肌腱损伤程度分级上差异无统计学意义(P>0.05)。定量分析:T2WI-FS_(IQMR)组图像的冈上肌、肱骨头和三角肌的SNR、冈上肌与肱骨头的CNR1和三角肌与肱骨头的CNR2均大于T2WI-FS_(快速)组和T2WI-FS_(常规)组(P<0.001)。结论在冈上肌肌腱损伤MRI扫描中,IQMR技术可以明显缩短扫描时间,提高图像质量,值得临床推广应用。