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An update on Ayurvedic herb Convolvulus pluricaulis Choisy 被引量:1
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作者 Parul Agarwa Bhawna Sharma +1 位作者 Anireen Fatima Sanjay Kumar Jain 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2014年第3期245-252,共8页
Convolvulus pluricaulis Choisy(C.pluricaulis)is a perennial herb that seems like morning glory.All parts of the herb are known to possess therapeutic benefits.The plant is used locally in Indian and Chinese medicine t... Convolvulus pluricaulis Choisy(C.pluricaulis)is a perennial herb that seems like morning glory.All parts of the herb are known to possess therapeutic benefits.The plant is used locally in Indian and Chinese medicine to cure various diseases.It is used in Ayurvedic formulation for chronic cough,sleeplessness,epilepsy,hallucinations,anxiety etc.Based on the comprehensive review of plant profile,pharmacognosy,phylochemistry,pharmacological and toxicological data on the C.pluricaulis,there will be more opportunities for the future research and development on the herb C.pluricaulis.Information on the C.pluricaulis was collected via electronic search(using Pub Med,SciFinder,Google Scholar and Web of Science)and library search for articles published in peer-reviewed journals.Furthermore,information also was obtained from some local books on ethnopharmacology.This paper covers the literature,primarily pharmacological,from 1985 to the end of 2012.The C.pluricaulis is an important indigenous medicine,which has a long medicinal application for liver disease,epileptic disease,microbial disease,cytotoxic and viral diseases,central nervous system(CNS)disease in Ayurvedic medicine,traditional Chinese medicine and other indigenous medical systems.The isolated metabolites and crude extract have exhibited a wide of in vitro and in vivo pharmacological effect,including CNS depression,anxiolytic,tranquillizing,antidepressant,antistress,neurodegenerative,antiamnesic,antioxidant,hypolipidemic,immunomodulatory,analgesic,antifungal,antibacterial,antidiabetic,antiulcer,anticatatonic,and cardiovascular activity.A chemical study of this plant was then initiated,which led to the isolation of carbohydrats,proteins,alkaloids,fatty acids,steroids,coumarins.flavanoids,and glycosides as active chemicals that bring about its biological effects.A scries of pharmacognostical studies of this plant show that it is a herb,its stem and leaves are hairy,more over it has two types of stomata,anisocytic and paracytic.A herb,C.pluricaulis has emerged as a good source of the traditional medicine for the treatment of liver disease,epileptic disease,microbial disease,cytotoxic and viral diseases,and CNS disease.Pharmacological results have validated the use of this species in traditional medicine.All the parts of the herb are known to possess therapeutic benefits.Expansion of research materials would provide more opportunities for the discovery of new bioactive principles from C.pluricaulis. 展开更多
关键词 convolvulus pluricaulis Choisy PHARMACOGNOSY Microscopy MACROSCOPY PHYTOCHEMISTRY PHARMACOLOGY
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Effects of Convolvulus arvensis Water Extract on Germination of Okra Under Different Seed Sizes
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作者 Abid Hussain Khoso Ghulam Mustafa Laghari +3 位作者 Aziz Ahmed Laghari Ali Muhammad Bozdar Asif Ali Kaleri Nasir Ali 《Journal of Northeast Agricultural University(English Edition)》 CAS 2017年第1期1-8,共8页
Convolvulus arvensis is a toxic allelopathic weed that suppresses germination and growth of crops. The prime object of present study was to investigate effect of Convolvulus arvensis water extract on germination and p... Convolvulus arvensis is a toxic allelopathic weed that suppresses germination and growth of crops. The prime object of present study was to investigate effect of Convolvulus arvensis water extract on germination and performance of okra with different seed sizes. The seeds of okra variety pusa green were separated into three different sizes, viz large size (4.00-5.00 mm), medium size (3.00-3.50 mm) and small size (2.00-3.50 mm), and then soaked in allelopathic plant bindweed water extract and kept in patrisdishes for germination into the germinator at 15℃. The experiment was laid out using Complete Randomized Design (CRD) with three replications. The results showed that after sowing of 12 days the highest germination was observed in non-treated seeds as compared to seeds treated in Convolvulus arvensis water extract for 1 h, further non-treated large seeds produced maximum plants as compared to treated small seeds after sowing of 24 days. Meanwhile, root length, shoot length, root fresh and dry weight, shoot fresh and dry weight were recorded higher in non-treated large seeds as compared to small seeds soaked for 1 h in Convolvulus arvensis allelopthic water extract. It could be found that Convolvulus arvensis affected germination, seed growth and overall performance of okra, further presence Convolvulus arvensis in crops could cause negative impact on germination and integrity of okra crops. 展开更多
关键词 OKRA GERMINATION convolvulus arvensis water extract
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Novel insights on acetylcholinesterase inhibition by Convolvulus pluricaulis,scopolamine and their combination in zebrafish
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作者 Kalyani Bindu Karunakaran Anand Thiyagaraj Kirankumar Santhakumar 《Natural Products and Bioprospecting》 2022年第1期56-70,共15页
Acetylcholinesterase(AChE)inhibitors increase the retention of acetylcholine(ACh)in synapses.Although they allevi-ate cognitive deficits in Alzheimer’s disease,their limited benefits warrant investigations of plant e... Acetylcholinesterase(AChE)inhibitors increase the retention of acetylcholine(ACh)in synapses.Although they allevi-ate cognitive deficits in Alzheimer’s disease,their limited benefits warrant investigations of plant extracts with similar properties.We studied the anti-AChE activity of Convolvulus pluricaulis(CP)in a zebrafish model of cognitive impair-ment induced by scopolamine(SCOP).CP is a perennial herb with anti-amnesiac and anxiolytic properties.It contains alkaloid,anthocyanin,coumarin,flavonoid,phytosterol and triterpenoid components.Isoxazole(ISOX)was used as a positive control for AChE inhibition.CP-treated 168 hpf larvae showed a similar pattern of AChE inhibition(in the myelencephalon and somites)as that of ISOX-treated larvae.CP was superior to ISOX as evidenced by the retention of avoidance response behavior in adult zebrafish.Molecular docking studies indicated that ISOX binds Ser203 of the catalytic triad on the human AChE.The active components of CP-scopoletin and kaempferol-were bound by His447 of the catalytic triad,the anionic subsite of the catalytic center,and the peripheral anionic site.This suggested the ability of CP to mediate both competitive and non-competitive modes of inhibition.Surprisingly,SCOP showed AChE inhibition in larvae,possibly mediated via the choline-binding sites.CP+SCOP induced a concentration-dependent increase in AChE inhibition and ACh depletion.Abnormal motor responses were observed with ISOX,CP,ISOX+SCOP,and CP+SCOP,indicative of undesirable effects on the peripheral cholinergic system.Our study proposes the examination of CP,SCOP,and CP+SCOP as potential AChE inhibitors for their ability to modulate cognitive deficits. 展开更多
关键词 Alzheimer’s disease ACETYLCHOLINESTERASE ZEBRAFISH convolvulus pluricaulis SCOPOLAMINE ISOXAZOLE
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Thermophilic anaerobic digestion of cattle manure reduces seed viability for four weed species 被引量:1
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作者 R.E.Eckford J.C.Newman +1 位作者 X.Li P.R.Watson 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2012年第1期71-75,共5页
Anaerobic digestion of manure and other biowaste has been gaining public attention for producing biogas as a renewable energy.More digestate materials after harvesting biogas available will be used as biofertilizers,s... Anaerobic digestion of manure and other biowaste has been gaining public attention for producing biogas as a renewable energy.More digestate materials after harvesting biogas available will be used as biofertilizers,soil conditioners and amendments for land application.However,digestate is required to be free of weed seeds.The effect of anaerobic digestion on the survival of weed seeds has not been studied extensively.This study examined four weed seeds,wild oats(Avena fatua L.),wild buckwheat(Polygonum convolvulus L.),wild mustard(Sinapis arvensis(DC.)L.C.Wheeler)and volunteer canola(Brassica napus L.)that were placed in batch cultures with feedlot cattle manure at 55℃for 7 and 24 hours.The results showed that after being subjected to anaerobic digestion for 7 hours,wild oats,volunteer canola and wild mustard had zero viability.Wild buckwheat had remaining viable seed after the 7 and 24 hour anaerobic digestion treatment as shown by the tetrazolium test.However,the remaining viable wild buckwheat seeds were considered to be incapable of normal growth and development. 展开更多
关键词 weed seeds anaerobic digestion Avena fatua Polygonum convolvulus Brassica napus Brassica kaber
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进口药材司卡摩尼亚脂质量标准提高研究 被引量:1
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作者 苏来曼·哈力克 白宇 艾力克木·吐尔逊 《药物分析杂志》 CAS CSCD 北大核心 2022年第2期352-360,共9页
目的:提高进口药材司卡摩尼亚脂的质量标准。方法:收集23批司卡摩尼亚脂药材,按照《中华人民共和国药典》方法进行系统的水分、总灰分、酸不溶性灰分、浸出物、重金属及有害元素和农药残留分析测定;分别采用UV、TLC进行定性鉴别研究;采... 目的:提高进口药材司卡摩尼亚脂的质量标准。方法:收集23批司卡摩尼亚脂药材,按照《中华人民共和国药典》方法进行系统的水分、总灰分、酸不溶性灰分、浸出物、重金属及有害元素和农药残留分析测定;分别采用UV、TLC进行定性鉴别研究;采用HPLC特征图谱研究,色谱柱为Agilent ODS-AQ(4.6 mm×150 mm,5μm),流动相为甲醇(A)-0.4%磷酸水溶液(B),梯度洗脱(0~5 min,30%A;5~10 min,30%A→40%A;10~15 min,40%A;15~20 min,40%A→55%A;20~30 min,55%A→70%A;30~32 min,70%A→95%A;32~45 min,90%A;45~55 min,100%A;55~60 min,100%A→30%A;60~70 min,30%A),流速为1.0 mL·min^(-1),检测波长为254 nm,柱温为35℃。建立HPLC指纹图谱,以4号峰为参照,采用《中药色谱指纹图谱相似度评价系统(2012版)》进行相似度评价。结果:司卡摩尼亚脂药材的性状鉴别专属;UV光谱鉴别具有特征性,薄层色谱鉴别色谱清晰、简便易行;检查项目确定了合理限度:水分≤3.5%,总灰分≤1.5%,95%乙醇浸出物≥95.0%,挥发性乙醚浸出物≤3.0%,重金属及有害元素、农药残留均未检出;HPLC特征指纹图谱确定5个色谱峰为共有指纹峰,其中选定一个为参照峰(S),结果为不同批次样品中共有峰相似度大于0.99,相对保留时间的RSD在0.32%~0.45%,表明不同批次样品共有成分的重现性好与伪品容易区分。结论:实验研究结果可作为司卡摩尼亚脂药材质量控制和评价标准。 展开更多
关键词 司卡摩尼亚脂 质量标准 UV鉴别 TLC鉴别 HPLC特征图谱:重金属及有害元素 农药残留 司卡摩尼亚根 convolvulus scammonia L
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