Urbanization is an inevitable trend of the development of human civilization. In the process of urbanization, human have learned lessons from protecting and inheriting cultural heritage or damaging and destroying it, ...Urbanization is an inevitable trend of the development of human civilization. In the process of urbanization, human have learned lessons from protecting and inheriting cultural heritage or damaging and destroying it, and also accumulated precious experience, fi nally formed a reasonable path to harmoniously deal with the relationship between urbanization and cultural heritage protection. Besides, the accomplishment has been incorporated into the cause of the symbiosis of cultural diversity and the construction of harmonious cities. China's contemporary urbanization has been developing rapidly, thus its cultural heritage protection is facing severe challenges. However, the relationship between urbanization and cultural heritage protection is not completely confl icting. Coordinative development between the two is increasingly becoming a social consensus. The win-win result of China's urbanization and cultural heritage protection will make its own contribution to the progress of world's urbanization and cultural heritage protection.展开更多
This paper tries to address the problem of a lack of ethics about intangible cultural heritage protection in current China from the perspective of the history of ideas. Though this is a not a new angle and many papers...This paper tries to address the problem of a lack of ethics about intangible cultural heritage protection in current China from the perspective of the history of ideas. Though this is a not a new angle and many papers have given a more or less comprehensive discussion about this, this paper will endeavor to give a more systematic account. Seen from the perspective of ethics, the protection of cultural heritage in China is mainly challenged by imbalance or deviation from four aspects： Firstly, from the aspect of political justice; secondly, from the aspect of a lack of civic awareness; thirdly, from the aspect of excessive nationalism; fourthly, from the aspect of silent intellectuals.展开更多
Through the factual analysis of the beginning,development,setbacks,and challenges of modern Iraqi archaeology and cultural relics protection,this paper carries out the research on different development stages under th...Through the factual analysis of the beginning,development,setbacks,and challenges of modern Iraqi archaeology and cultural relics protection,this paper carries out the research on different development stages under the current international and domestic political backgrounds,and analyzes the protection of Iraqi cultural heritage and the source of the predicament.There are many reasons for the tragedy of Iraqi cultural heritage,including military conflict,international economic situation,lack of state power,severe poverty,and religious conflict.展开更多
Among the three methods of intangible cultural heritage （ICH） protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of le...Among the three methods of intangible cultural heritage （ICH） protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of legal relations, coordination mecha- nisms and modes of operation by the Wuhan Tourism Investment Group in the course of safeguarding intangible cultural heritage in handicrafts, this paper discusses the sustainable ＂Wuhan Model＂ and its human values.展开更多
Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarize...Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural heritage.Through a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction process.Traditional villages face the risk of declining or even loss of heritage value.In order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional villages.The research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process.展开更多
Through the review and reflection on the protection of rural culture,this paper thinks that there are many factors affecting the protection of rural culture,which need to be analyzed systematically.This paper takes th...Through the review and reflection on the protection of rural culture,this paper thinks that there are many factors affecting the protection of rural culture,which need to be analyzed systematically.This paper takes the cultural meme theory as the basic theory of rural cultural protection and inheritance,and constructs a set of factors affecting the protection of rural culture from two aspects of external environment and group psychology.Based on 335 questionnaires of rural tourism destination residents in Jiangsu Province,this paper deeply analyzes the influence of rural cultural protection and its driving factors,and uses structural equation model to calculate.The empirical results show that the group psychological factors as an intermediate variable,physical environmental factors and social environmental factors significantly affect the group psychological factors,thus affecting the rural cultural protection.At the same time,the impact of cultural and tourism utilization factors on rural cultural protection is also significant.From the perspective of the main body of rural cultural protection,this paper explores the psychology of the main body of rural cultural protection,promotes the upgrading of rural tourism quality and efficiency while protecting rural culture,deepens theoretical research and strengthens practical application,which has important enlightenment significance for realizing the healthy inheritance of rural culture.On the other hand,this paper can provide reasonable suggestions for the governance and development of rural traditional tourism.展开更多
In order to deal with the special spatio-temporal environmental changes encountered in the process of open-cast mining,taking Huolinhe No.1 Open-cast Mine as the research object,this paper studied its typical problems...In order to deal with the special spatio-temporal environmental changes encountered in the process of open-cast mining,taking Huolinhe No.1 Open-cast Mine as the research object,this paper studied its typical problems in river reconstruction and cultural relics protection.The study focused on eight key core aspects,including the design optimization of the spatial layout of the mining area,the accurate estimation of the mineral resources reserves,the scientific theoretical demonstration of the mining scale,the fine analysis and calculation of the stripping ratio,the comprehensive consideration of the transport distance and efficiency,the accurate judgment of the best time for the implementation of the transformation,the analysis and evaluation of the slope stability,and the overall planning of the production system.The results show that the extracted problem-solving strategies and scheme system for special mining conditions can not only provide specific and practical guidance for Huolinhe No.1 Open-cast Mine,but also serve as a valuable reference and practical reference for other open-cast mine enterprises facing similar challenges.展开更多
This study organized the current status of tangible cultural heritage along the Tonghui River.The spaces along the Tonghui River were classified according to the farmland,suburban areas,urban residential areas,and urb...This study organized the current status of tangible cultural heritage along the Tonghui River.The spaces along the Tonghui River were classified according to the farmland,suburban areas,urban residential areas,and urban center areas.Spatial analysis of the current situation was conducted through Baidu Street View images,with a focus on evaluating the spatial environment around the tangible cultural heritage.Negative factors affecting the reuse of cultural heritage were analyzed,such as poor appearance of buildings and low accessibility of transportation along the Tonghui River.展开更多
Several studies have indicated that fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica could inhibit the activation of platelets directly by reducing the platelet aggreg...Several studies have indicated that fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica could inhibit the activation of platelets directly by reducing the platelet aggregation. To explore the direct effect of LMW fucoidan on the platelet system furthermore and examine the possible mechanism, the endothelial protection and inhibits platelet activation effects of two LMW fucoidan were investigated. In the present study, Endothelial injury model of rats was made by injection of adrenaline(0.4 mg kg-1) and human umbilical vein endothelial cells were cultured. v WF level was be investigated in vivo and in vitro as an important index of endothelial injury. LMW fucoidan could significantly reduce v WF level in vascular endothelial injury rats and also significantly reduce v WF level in vitro. The number of EMPs was be detected as another important index of endothelial injury. The results showed that LMW fucoidan reduced EMPs stimulated by tumor necrosis factor. In this study, it was found that by inhibiting platelet adhesion, LMW fucoidan played a role in anti-thrombosis and the specific mechanism of action is to inhibit the flow of extracellular Ca2+. All in a word, LMW fucoidan could inhibit the activation of platelets indirectly by reducing the concentration of EMPs and v WF, at the same time; LMW fucoidan inhibited the activation of platelets directly by inhibiting the flow of extracellular Ca2+.展开更多
The innocent Tuwa people live in Kanas Lake, a world famous national reserve in northern Xinjiang. With therapid development of tourism today, Tuwa people are finally involved in tourism industry. The development of t...The innocent Tuwa people live in Kanas Lake, a world famous national reserve in northern Xinjiang. With therapid development of tourism today, Tuwa people are finally involved in tourism industry. The development of tourismis a two-edged sword. On the one hand, it boosts the revival of Tuwa culture, provides a large number of employmentopportunities and cross-cultural exchanges, and improves material welfare for Tuwa people. On the other hand, somedisadvantages have also resulted from tourism development, such as the unauthentic exhibition of Tuwa culture, limitedtourists, Tuwa group interaction, and limited material improvement for the Tuwa, etc. This paper takes Tuwa people asa case, illustrates the types, characteristics and the conditions for the development of Tuwa culture, explores the advan-tages and disadvantages resulting from the development of folk-custom tourism industry and then puts forwardsrecommendations on the protection for local cultures as follows: (1) attach great importance to Tuwa culture in thetourism development of Kanas Lake Visitor Attraction; (2) construct the aboriginal village with the consciousness ofprotection; (3) remove the Tuwa village; (4) consummate the management mode and let Tuwa people really benefit fromtourism; (5) restrict the grazing in the scenic spots and protect natural grassland; (6) promote Tuwa people’s ability ofself-supervision and self-management; (7) exhibit Tuwa culture authentically.展开更多
From the perspective of cultural ecology, the thesis takes the linguistic culture resources as the research object, analyzes the diversified and endangered characteristics of linguistic cultural resources, and then co...From the perspective of cultural ecology, the thesis takes the linguistic culture resources as the research object, analyzes the diversified and endangered characteristics of linguistic cultural resources, and then comes up with three different strategies to protect intangible cultural heritage of linguistic culture domain and to develop cultural industry. Then it stresses cultural self-consciousness, sustainable development of cultural ecology to develop and protect the linguistic culture resources under the protection mechanism of intangible cultural heritage.展开更多
On September 25, 2008, the Information Office of the State Council of the People＇s Republic of China released an article entitled the ＂Protection and Development of Tibetan Culture.＂ The following is the main part ...On September 25, 2008, the Information Office of the State Council of the People＇s Republic of China released an article entitled the ＂Protection and Development of Tibetan Culture.＂ The following is the main part of the text.展开更多
Taking Xiaoluoshui Village by the Lugu Lake in Lijiang,Yunnan Province for example,this paper introduced traditional culture and residential culture of Mosuo people,as well as the confusion of Mosuo people in cultural...Taking Xiaoluoshui Village by the Lugu Lake in Lijiang,Yunnan Province for example,this paper introduced traditional culture and residential culture of Mosuo people,as well as the confusion of Mosuo people in cultural inheritance and development brought by modern society,on this basis,proposed the suggestion for inheriting and promoting local residential culture,i.e.paving a road for Mosuo people pursuing their own culture by establishing communication spaces for Mosuo Culture.展开更多
Ganoderma lucidum polysaccharides have protective effects against apoptosis in neurons exposed to ischemia/reperfusion injury, but the mechanisms are unclear. The goal of this study was to investigate the underlying m...Ganoderma lucidum polysaccharides have protective effects against apoptosis in neurons exposed to ischemia/reperfusion injury, but the mechanisms are unclear. The goal of this study was to investigate the underlying mechanisms of the effects of ganoderma lucidum polysaccharides against oxidative stress-induced neuronal apoptosis. Hydrogen peroxide（H_2O_2） was used to induce apoptosis in cultured cerebellar granule cells. In these cells, ganoderma lucidum polysaccharides remarkably suppressed H_2O_2-induced apoptosis, decreased expression of caspase-3, Bax and Bim and increased that of Bcl-2. These findings suggested that ganoderma lucidum polysaccharides regulate expression of apoptosis-associated proteins, inhibit oxidative stress-induced neuronal apoptosis and, therefore, have significant neuroprotective effects.展开更多
Since the establishment of treaty ports in the mid-19th century,the urban development of many Chinese cities,and notably of Shanghai,has been heavily influenced by global economic flows and global urban and architectu...Since the establishment of treaty ports in the mid-19th century,the urban development of many Chinese cities,and notably of Shanghai,has been heavily influenced by global economic flows and global urban and architectural practices.In Shanghai,extensive lilong neighbourhoods stand as remnants of the treaty port era.Many of these historic districts are in close proximity to rapidly transforming areas of the city,creating civic tension around demolition,conservation and the redevelopment of colonial heritage.Examining the listed Bugaoli community in Shanghai’s old French Concession,the heritage strategies applied under the particular Cultural Relics Protection System(CRPS),and the discourse of local residents interviewed in the context of this project,this paper reveals the paradoxes around urban heritage conservation and urban development by considering three different temporalities:legislative time,economic time and citizen time.The paper argues that actors involved in heritage practices should consider both space and time related issues in urban heritage conservation.Historic communities such as Bugaoli experience conflicts between conservation and the demands of everyday life.They underline and require a heritage strategy that acknowledges diverse temporalities and balances legal norms,economic interests and the public’s demands.展开更多
Paper-based relics as important carriers of human history and civilization have been facing severe damage problems,and their protection is a major project for cultural heritage restoration.So far,safe,high-efficiency,...Paper-based relics as important carriers of human history and civilization have been facing severe damage problems,and their protection is a major project for cultural heritage restoration.So far,safe,high-efficiency,and multifunctional protection materials are still urgent to be developed.Herein,through screening a series of alkaline nano-oxides and cleverly combining the advantages of modified natural polymer(quaternized chitosan)and inorganic nanomaterials(Zn O),we successfully prepared their functional nanocomposites with multiple properties and pioneered their smart application for multifunctional protection of paper relics.By spraying loads,this kind of nanocomposites can effectively and safely inhibit the acid degradation of paper relics and long-term maintain a natural or weak basic state even under harsh accelerated aging conditions.Meanwhile,the coating of nanocomposites does not change the chromatic aberration but partially improves the hydrophobicity.Moreover,the mechanical properties of paper relics are reinforced up to more than one time for all-around tensile strength,folding endurance,and tearing strength.It is worth noting that the usage of nanocomposites can avoid the discoloration or fading of p H-sensitive pigments/dyes and prevent the blue/red inks from ink-spreading.By integrating the anti-microorganism effects of the two components,the nanocomposites have exhibited a broad antimicrobial capacity for both fungi(e.g.,Plectosphaerella cucumerina and Aspergillus unguis)and bacteria(e.g.,Staphylococcus aureus).The acquired knowledge not only represents an advanced step for designing functionalized inorganic/polymer nanocomposite but also sheds light on the multi-functional integrated protection of paperbased relics.展开更多
文摘Urbanization is an inevitable trend of the development of human civilization. In the process of urbanization, human have learned lessons from protecting and inheriting cultural heritage or damaging and destroying it, and also accumulated precious experience, fi nally formed a reasonable path to harmoniously deal with the relationship between urbanization and cultural heritage protection. Besides, the accomplishment has been incorporated into the cause of the symbiosis of cultural diversity and the construction of harmonious cities. China's contemporary urbanization has been developing rapidly, thus its cultural heritage protection is facing severe challenges. However, the relationship between urbanization and cultural heritage protection is not completely confl icting. Coordinative development between the two is increasingly becoming a social consensus. The win-win result of China's urbanization and cultural heritage protection will make its own contribution to the progress of world's urbanization and cultural heritage protection.
文摘This paper tries to address the problem of a lack of ethics about intangible cultural heritage protection in current China from the perspective of the history of ideas. Though this is a not a new angle and many papers have given a more or less comprehensive discussion about this, this paper will endeavor to give a more systematic account. Seen from the perspective of ethics, the protection of cultural heritage in China is mainly challenged by imbalance or deviation from four aspects： Firstly, from the aspect of political justice; secondly, from the aspect of a lack of civic awareness; thirdly, from the aspect of excessive nationalism; fourthly, from the aspect of silent intellectuals.
文摘Through the factual analysis of the beginning,development,setbacks,and challenges of modern Iraqi archaeology and cultural relics protection,this paper carries out the research on different development stages under the current international and domestic political backgrounds,and analyzes the protection of Iraqi cultural heritage and the source of the predicament.There are many reasons for the tragedy of Iraqi cultural heritage,including military conflict,international economic situation,lack of state power,severe poverty,and religious conflict.
文摘Among the three methods of intangible cultural heritage （ICH） protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of legal relations, coordination mecha- nisms and modes of operation by the Wuhan Tourism Investment Group in the course of safeguarding intangible cultural heritage in handicrafts, this paper discusses the sustainable ＂Wuhan Model＂ and its human values.
基金funded by the National Natural Science Foundation of China under the project“Research on Urban Spatial Coupling Mechanism Between Urban Epidemic Spreading and Vulnerability and Planning Response in Chengdu-Chongqing Area”(Grant No.52078423)the Major Program of Sichuan Provincial Scientific Research under the Project“Research and Demonstration of Resilient Collaborative Planning and Design for Park Cities”(Grant No.2020YFS0054)the Sichuan Provincial Science and Technology Innovation Platform and Talent Plan"Research on the Construction and Development Strategies of Several Major Infrastructure Systems for New Smart Cities"(Grant No.2022JDR0356).
文摘Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster reconstruction.This paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural heritage.Through a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction process.Traditional villages face the risk of declining or even loss of heritage value.In order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional villages.The research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process.
基金supported by the 2020 College Science and Technology Plan Youth Support Project(Grant No.2020kj015)2020 College Educational Science Research Project(Grant No.JK202013)+1 种基金2020 Jiangsu University Student Entrepreneurship Project(Grant No.202013103042T)2020 College School-Enterprise Cooperation Major Project(Grant No.2020kj020)
文摘Through the review and reflection on the protection of rural culture,this paper thinks that there are many factors affecting the protection of rural culture,which need to be analyzed systematically.This paper takes the cultural meme theory as the basic theory of rural cultural protection and inheritance,and constructs a set of factors affecting the protection of rural culture from two aspects of external environment and group psychology.Based on 335 questionnaires of rural tourism destination residents in Jiangsu Province,this paper deeply analyzes the influence of rural cultural protection and its driving factors,and uses structural equation model to calculate.The empirical results show that the group psychological factors as an intermediate variable,physical environmental factors and social environmental factors significantly affect the group psychological factors,thus affecting the rural cultural protection.At the same time,the impact of cultural and tourism utilization factors on rural cultural protection is also significant.From the perspective of the main body of rural cultural protection,this paper explores the psychology of the main body of rural cultural protection,promotes the upgrading of rural tourism quality and efficiency while protecting rural culture,deepens theoretical research and strengthens practical application,which has important enlightenment significance for realizing the healthy inheritance of rural culture.On the other hand,this paper can provide reasonable suggestions for the governance and development of rural traditional tourism.
文摘In order to deal with the special spatio-temporal environmental changes encountered in the process of open-cast mining,taking Huolinhe No.1 Open-cast Mine as the research object,this paper studied its typical problems in river reconstruction and cultural relics protection.The study focused on eight key core aspects,including the design optimization of the spatial layout of the mining area,the accurate estimation of the mineral resources reserves,the scientific theoretical demonstration of the mining scale,the fine analysis and calculation of the stripping ratio,the comprehensive consideration of the transport distance and efficiency,the accurate judgment of the best time for the implementation of the transformation,the analysis and evaluation of the slope stability,and the overall planning of the production system.The results show that the extracted problem-solving strategies and scheme system for special mining conditions can not only provide specific and practical guidance for Huolinhe No.1 Open-cast Mine,but also serve as a valuable reference and practical reference for other open-cast mine enterprises facing similar challenges.
基金Innovation and Entrepreneurship Training Program for College Students.
文摘This study organized the current status of tangible cultural heritage along the Tonghui River.The spaces along the Tonghui River were classified according to the farmland,suburban areas,urban residential areas,and urban center areas.Spatial analysis of the current situation was conducted through Baidu Street View images,with a focus on evaluating the spatial environment around the tangible cultural heritage.Negative factors affecting the reuse of cultural heritage were analyzed,such as poor appearance of buildings and low accessibility of transportation along the Tonghui River.
文摘Several studies have indicated that fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica could inhibit the activation of platelets directly by reducing the platelet aggregation. To explore the direct effect of LMW fucoidan on the platelet system furthermore and examine the possible mechanism, the endothelial protection and inhibits platelet activation effects of two LMW fucoidan were investigated. In the present study, Endothelial injury model of rats was made by injection of adrenaline(0.4 mg kg-1) and human umbilical vein endothelial cells were cultured. v WF level was be investigated in vivo and in vitro as an important index of endothelial injury. LMW fucoidan could significantly reduce v WF level in vascular endothelial injury rats and also significantly reduce v WF level in vitro. The number of EMPs was be detected as another important index of endothelial injury. The results showed that LMW fucoidan reduced EMPs stimulated by tumor necrosis factor. In this study, it was found that by inhibiting platelet adhesion, LMW fucoidan played a role in anti-thrombosis and the specific mechanism of action is to inhibit the flow of extracellular Ca2+. All in a word, LMW fucoidan could inhibit the activation of platelets indirectly by reducing the concentration of EMPs and v WF, at the same time; LMW fucoidan inhibited the activation of platelets directly by inhibiting the flow of extracellular Ca2+.
文摘The innocent Tuwa people live in Kanas Lake, a world famous national reserve in northern Xinjiang. With therapid development of tourism today, Tuwa people are finally involved in tourism industry. The development of tourismis a two-edged sword. On the one hand, it boosts the revival of Tuwa culture, provides a large number of employmentopportunities and cross-cultural exchanges, and improves material welfare for Tuwa people. On the other hand, somedisadvantages have also resulted from tourism development, such as the unauthentic exhibition of Tuwa culture, limitedtourists, Tuwa group interaction, and limited material improvement for the Tuwa, etc. This paper takes Tuwa people asa case, illustrates the types, characteristics and the conditions for the development of Tuwa culture, explores the advan-tages and disadvantages resulting from the development of folk-custom tourism industry and then puts forwardsrecommendations on the protection for local cultures as follows: (1) attach great importance to Tuwa culture in thetourism development of Kanas Lake Visitor Attraction; (2) construct the aboriginal village with the consciousness ofprotection; (3) remove the Tuwa village; (4) consummate the management mode and let Tuwa people really benefit fromtourism; (5) restrict the grazing in the scenic spots and protect natural grassland; (6) promote Tuwa people’s ability ofself-supervision and self-management; (7) exhibit Tuwa culture authentically.
文摘From the perspective of cultural ecology, the thesis takes the linguistic culture resources as the research object, analyzes the diversified and endangered characteristics of linguistic cultural resources, and then comes up with three different strategies to protect intangible cultural heritage of linguistic culture domain and to develop cultural industry. Then it stresses cultural self-consciousness, sustainable development of cultural ecology to develop and protect the linguistic culture resources under the protection mechanism of intangible cultural heritage.
文摘On September 25, 2008, the Information Office of the State Council of the People＇s Republic of China released an article entitled the ＂Protection and Development of Tibetan Culture.＂ The following is the main part of the text.
文摘Taking Xiaoluoshui Village by the Lugu Lake in Lijiang,Yunnan Province for example,this paper introduced traditional culture and residential culture of Mosuo people,as well as the confusion of Mosuo people in cultural inheritance and development brought by modern society,on this basis,proposed the suggestion for inheriting and promoting local residential culture,i.e.paving a road for Mosuo people pursuing their own culture by establishing communication spaces for Mosuo Culture.
文摘Ganoderma lucidum polysaccharides have protective effects against apoptosis in neurons exposed to ischemia/reperfusion injury, but the mechanisms are unclear. The goal of this study was to investigate the underlying mechanisms of the effects of ganoderma lucidum polysaccharides against oxidative stress-induced neuronal apoptosis. Hydrogen peroxide（H_2O_2） was used to induce apoptosis in cultured cerebellar granule cells. In these cells, ganoderma lucidum polysaccharides remarkably suppressed H_2O_2-induced apoptosis, decreased expression of caspase-3, Bax and Bim and increased that of Bcl-2. These findings suggested that ganoderma lucidum polysaccharides regulate expression of apoptosis-associated proteins, inhibit oxidative stress-induced neuronal apoptosis and, therefore, have significant neuroprotective effects.
文摘Since the establishment of treaty ports in the mid-19th century,the urban development of many Chinese cities,and notably of Shanghai,has been heavily influenced by global economic flows and global urban and architectural practices.In Shanghai,extensive lilong neighbourhoods stand as remnants of the treaty port era.Many of these historic districts are in close proximity to rapidly transforming areas of the city,creating civic tension around demolition,conservation and the redevelopment of colonial heritage.Examining the listed Bugaoli community in Shanghai’s old French Concession,the heritage strategies applied under the particular Cultural Relics Protection System(CRPS),and the discourse of local residents interviewed in the context of this project,this paper reveals the paradoxes around urban heritage conservation and urban development by considering three different temporalities:legislative time,economic time and citizen time.The paper argues that actors involved in heritage practices should consider both space and time related issues in urban heritage conservation.Historic communities such as Bugaoli experience conflicts between conservation and the demands of everyday life.They underline and require a heritage strategy that acknowledges diverse temporalities and balances legal norms,economic interests and the public’s demands.
基金supported by the National Natural Science Foundation of China(Grant No.22175040)the Natural Science Foundation of Shanghai(Grant No.21ZR1405100)+1 种基金the Foundation of State Key Laboratory of Biobased Material and Green PapermakingQilu University of Technology,Shandong Academy of Sciences(Grant Nos.GZKF202109,GZKF202210)。
文摘Paper-based relics as important carriers of human history and civilization have been facing severe damage problems,and their protection is a major project for cultural heritage restoration.So far,safe,high-efficiency,and multifunctional protection materials are still urgent to be developed.Herein,through screening a series of alkaline nano-oxides and cleverly combining the advantages of modified natural polymer(quaternized chitosan)and inorganic nanomaterials(Zn O),we successfully prepared their functional nanocomposites with multiple properties and pioneered their smart application for multifunctional protection of paper relics.By spraying loads,this kind of nanocomposites can effectively and safely inhibit the acid degradation of paper relics and long-term maintain a natural or weak basic state even under harsh accelerated aging conditions.Meanwhile,the coating of nanocomposites does not change the chromatic aberration but partially improves the hydrophobicity.Moreover,the mechanical properties of paper relics are reinforced up to more than one time for all-around tensile strength,folding endurance,and tearing strength.It is worth noting that the usage of nanocomposites can avoid the discoloration or fading of p H-sensitive pigments/dyes and prevent the blue/red inks from ink-spreading.By integrating the anti-microorganism effects of the two components,the nanocomposites have exhibited a broad antimicrobial capacity for both fungi(e.g.,Plectosphaerella cucumerina and Aspergillus unguis)and bacteria(e.g.,Staphylococcus aureus).The acquired knowledge not only represents an advanced step for designing functionalized inorganic/polymer nanocomposite but also sheds light on the multi-functional integrated protection of paperbased relics.
