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Aminated Cyclopropylmethylphosphonates as Potent Prostate Cancer Inhibitors
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作者 Abed Al Aziz Al Quntar Ibrahim Abasy 《Journal of Biosciences and Medicines》 2024年第7期239-244,共6页
Inspired by the anti-pancreatic promising results of our novel aminated cyclopropylmethylphosphonate compounds, an in vitro anti-prostate cancer activity exploration of these compounds was carried out on human prostat... Inspired by the anti-pancreatic promising results of our novel aminated cyclopropylmethylphosphonate compounds, an in vitro anti-prostate cancer activity exploration of these compounds was carried out on human prostate cancer cell line PC-3, and showed potent inhibiting activity at low micromolar concentrations (with an IC50 of approximately 45 μM). 展开更多
关键词 Prostate Cancer Cancer cyclopropylphophonates AMINOPHOSPHONATES CYCLOPROPANES PHOSPHONATES Alkynylphosphonates ANTI-CANCER Prostate
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