Two new steroidal glycosides named cyanoauriculoside A （1） and B （2）, have been isolated from the roots of Cynanchum auriculatum Royle ex Wight. The structure of cyanoauriculoside A （1） was determined to be 20-O...Two new steroidal glycosides named cyanoauriculoside A （1） and B （2）, have been isolated from the roots of Cynanchum auriculatum Royle ex Wight. The structure of cyanoauriculoside A （1） was determined to be 20-O-acetyl-penupogenin-3-O-β-D- glucopyranosyl-（ 1 →4）-β-D-glucopyranosyl-（ 1 →4）-α -L-cymaropyranosyl- （ 1 →4）-β-D-cymaropyranosyl- （ 1 →4）-α-L-diginopyranosyl-（1→4）-β-D-cymaropyranoside. Cyanoauriculoside B （2） was characterized as 20-O-acetylpenupogenin-3-O-β-D-gluco- pyranosyl-（ 1 →4）-α-L-cymaropyranosyl-（ 1 →4）-β-D-cymaropyranosyl-（ 1 →4）-α-L-diginopyranosyl-（ 1 →4）-β-D-cymaropyranoside. The structures of these compounds were elucidated based on the chemical and spectroscopic evidence.展开更多
Objective： To study the chemical constituents from the Et OAc extract of endophytic fungal Plectosphaerella cucumerina YCTA2 Z1.Methods： The chemical constituents were isolated and purified by silica gel column,Seph...Objective： To study the chemical constituents from the Et OAc extract of endophytic fungal Plectosphaerella cucumerina YCTA2 Z1.Methods： The chemical constituents were isolated and purified by silica gel column,Sephadex LH-20,and reverse-phase C-18 column chromatography as well as crystallization.Results： Thirteen compounds were isolated from the EtOAc extract of the fungal strain YCTA2 Z1.Their chemical structures were elucidated according to the spectral evidence.They were identified as caudatin（1）,baishouwubenzophenone（2）,cynandione B（3）,asterbatanoside A（4）,p-hydroxyphenethyl-O-β-D-glycoside（5）,caffeic acid（6）,ferulic acid（7）,2,5-dihydroxyacetophenone（8）,protocatechuic acid（9）,vanillic acid（10）,stearic acid（11）,azelaic acid（12）,and succinic acid（13）.Conclusions： It is the first chemical study on endophytic fungi from Cynanchum auriculatum and all the compounds are obtained from the species,the genus,as well as the family Plectosphaerellaceae for the first time.展开更多
Objective To study the chemical constituents of Cynanchum auriculatum.Methods Two steroidal glycosides were purified by column chromatography and their structures were elucidated by spectroscopic analysis.Results and ...Objective To study the chemical constituents of Cynanchum auriculatum.Methods Two steroidal glycosides were purified by column chromatography and their structures were elucidated by spectroscopic analysis.Results and Conclusion Compound 1 is a new steroidal glycoside,named kidjoranin-3-O-β-D-cymaropyranoside.Compound 2 is isolated from this plant for the first time.展开更多
基金financial support of this work by the National Key Technology R&D Program in the 11th Five Year Plan of China(No.2007BAI48B08)
文摘Two new steroidal glycosides named cyanoauriculoside A （1） and B （2）, have been isolated from the roots of Cynanchum auriculatum Royle ex Wight. The structure of cyanoauriculoside A （1） was determined to be 20-O-acetyl-penupogenin-3-O-β-D- glucopyranosyl-（ 1 →4）-β-D-glucopyranosyl-（ 1 →4）-α -L-cymaropyranosyl- （ 1 →4）-β-D-cymaropyranosyl- （ 1 →4）-α-L-diginopyranosyl-（1→4）-β-D-cymaropyranoside. Cyanoauriculoside B （2） was characterized as 20-O-acetylpenupogenin-3-O-β-D-gluco- pyranosyl-（ 1 →4）-α-L-cymaropyranosyl-（ 1 →4）-β-D-cymaropyranosyl-（ 1 →4）-α-L-diginopyranosyl-（ 1 →4）-β-D-cymaropyranoside. The structures of these compounds were elucidated based on the chemical and spectroscopic evidence.
基金National Natural Science Foundation of China (21502014,81673017,51408094)Natural Science Foundation of Liaoning Province,China (201602114)Research Foundation of Educational Committee of Liaoning Province,China (JDL2017027)
文摘Objective： To study the chemical constituents from the Et OAc extract of endophytic fungal Plectosphaerella cucumerina YCTA2 Z1.Methods： The chemical constituents were isolated and purified by silica gel column,Sephadex LH-20,and reverse-phase C-18 column chromatography as well as crystallization.Results： Thirteen compounds were isolated from the EtOAc extract of the fungal strain YCTA2 Z1.Their chemical structures were elucidated according to the spectral evidence.They were identified as caudatin（1）,baishouwubenzophenone（2）,cynandione B（3）,asterbatanoside A（4）,p-hydroxyphenethyl-O-β-D-glycoside（5）,caffeic acid（6）,ferulic acid（7）,2,5-dihydroxyacetophenone（8）,protocatechuic acid（9）,vanillic acid（10）,stearic acid（11）,azelaic acid（12）,and succinic acid（13）.Conclusions： It is the first chemical study on endophytic fungi from Cynanchum auriculatum and all the compounds are obtained from the species,the genus,as well as the family Plectosphaerellaceae for the first time.
基金support of National Natural Science Foundation of China (30370292)Natural Science Foundation of Jiangsu Province (BK2004062, BE2003329, BG200611)
文摘Objective To study the chemical constituents of Cynanchum auriculatum.Methods Two steroidal glycosides were purified by column chromatography and their structures were elucidated by spectroscopic analysis.Results and Conclusion Compound 1 is a new steroidal glycoside,named kidjoranin-3-O-β-D-cymaropyranoside.Compound 2 is isolated from this plant for the first time.
文摘目的 从萝科鹅绒藤属植物耳叶牛皮消 (CynanchumauriculatumRoyleexWight)块根中分离出有细胞毒活性的 2种C2 1甾体苷。方法 用柱色谱和HPLC法分离纯化 ,通过化学降解及光谱分析 (UV ,IR ,1HNMR ,13 CNMR ,DEPT ,HR FAB MS ,FAB MS ,HMQC和HMBC)鉴定其化学结构。结果 从白首乌中分离得到白首乌新苷A(I)与B(II) ,其化学结构分别为 :告达庭 3 O β D 葡吡喃糖基 (1→ 4) β D 磁麻吡喃糖基 (1→ 4) β D 夹竹桃吡喃糖基 (1→ 4) β D 磁麻吡喃糖苷 ;告达庭 3 O β D 葡吡喃糖基 (1→ 4) β D 夹竹桃吡喃糖基 (1→ 4) β D 洋地黄毒吡喃糖基 (1→ 4) β D 磁麻吡喃糖苷。 结论 白首乌新苷A和B均为新C2
