Various reports indicate that the incidence of congenital hypothyroidism is increasing in developed nations, and that improved detection and more inclusive criteria for the disease do not explain this trend entirely. ...Various reports indicate that the incidence of congenital hypothyroidism is increasing in developed nations, and that improved detection and more inclusive criteria for the disease do not explain this trend entirely. One risk factor documented in numerous studies is exposure to radioactive iodine found in nuclear weapons test fallout and nuclear reactor emissions. Large amounts of fallout disseminated worldwide from the meltdowns in four reactors at the Fukushima-Dai-ichi plant in Japan beginning March 11, 2011 included radioiodine isotopes. Just days after the meltdowns, I-131 concentrations in US precipitation was measured up to 211 times above normal. Highest levels of I-131 and airborne gross beta were documented in the five US States on the Pacific Ocean. The number of congenital hypothyroid cases in these five states from March 17-December 31, 2011 was 16% greater than for the same period in 2010, compared to a 3% decline in 36 other US States展开更多
Radiation exposure has been linked to increased risk of congenital hypothyroidism (CH) for decades. CH is a relatively uncommon condition, occurring in about 1 of 2000 US births. Thyroid Stimulating Hormone (TSH) leve...Radiation exposure has been linked to increased risk of congenital hypothyroidism (CH) for decades. CH is a relatively uncommon condition, occurring in about 1 of 2000 US births. Thyroid Stimulating Hormone (TSH) levels for each child born in California permitted an analysis of combined confirmed and borderline CH cases. Borderline/confirmed CH cases are more than seven times greater than just confirmed cases. Airborne levels of gross beta nuclear radiation in the US were elevated in the period starting several days after the Fukushima nuclear meltdown, especially in west coast states like California. The borderline/confirmed CH rate for newborns during the last 9.5 months in 2011 (exposed to Fukushima in utero) vs. births during other periods in 2011 and 2012 (not exposed) was significantly elevated, suggesting that adverse health effects to the newborn thyroid were not restricted to just a small number of confirmed CH cases. The sensitivity of the fetus to radiation exposure, plus the presence of thyroid-seeking radioiodine, suggest further analysis of Fukushima’s potential to cause adverse health effects in newborns is needed.展开更多
文摘Various reports indicate that the incidence of congenital hypothyroidism is increasing in developed nations, and that improved detection and more inclusive criteria for the disease do not explain this trend entirely. One risk factor documented in numerous studies is exposure to radioactive iodine found in nuclear weapons test fallout and nuclear reactor emissions. Large amounts of fallout disseminated worldwide from the meltdowns in four reactors at the Fukushima-Dai-ichi plant in Japan beginning March 11, 2011 included radioiodine isotopes. Just days after the meltdowns, I-131 concentrations in US precipitation was measured up to 211 times above normal. Highest levels of I-131 and airborne gross beta were documented in the five US States on the Pacific Ocean. The number of congenital hypothyroid cases in these five states from March 17-December 31, 2011 was 16% greater than for the same period in 2010, compared to a 3% decline in 36 other US States
文摘Radiation exposure has been linked to increased risk of congenital hypothyroidism (CH) for decades. CH is a relatively uncommon condition, occurring in about 1 of 2000 US births. Thyroid Stimulating Hormone (TSH) levels for each child born in California permitted an analysis of combined confirmed and borderline CH cases. Borderline/confirmed CH cases are more than seven times greater than just confirmed cases. Airborne levels of gross beta nuclear radiation in the US were elevated in the period starting several days after the Fukushima nuclear meltdown, especially in west coast states like California. The borderline/confirmed CH rate for newborns during the last 9.5 months in 2011 (exposed to Fukushima in utero) vs. births during other periods in 2011 and 2012 (not exposed) was significantly elevated, suggesting that adverse health effects to the newborn thyroid were not restricted to just a small number of confirmed CH cases. The sensitivity of the fetus to radiation exposure, plus the presence of thyroid-seeking radioiodine, suggest further analysis of Fukushima’s potential to cause adverse health effects in newborns is needed.
