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Novel Investigation of Stochastic Fractional Differential Equations Measles Model via the White Noise and Global Derivative Operator Depending on Mittag-Leffler Kernel 被引量:1
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作者 Saima Rashid Fahd Jarad 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期2289-2327,共39页
Because of the features involved with their varied kernels,differential operators relying on convolution formulations have been acknowledged as effective mathematical resources for modeling real-world issues.In this p... Because of the features involved with their varied kernels,differential operators relying on convolution formulations have been acknowledged as effective mathematical resources for modeling real-world issues.In this paper,we constructed a stochastic fractional framework of measles spreading mechanisms with dual medication immunization considering the exponential decay and Mittag-Leffler kernels.In this approach,the overall population was separated into five cohorts.Furthermore,the descriptive behavior of the system was investigated,including prerequisites for the positivity of solutions,invariant domain of the solution,presence and stability of equilibrium points,and sensitivity analysis.We included a stochastic element in every cohort and employed linear growth and Lipschitz criteria to show the existence and uniqueness of solutions.Several numerical simulations for various fractional orders and randomization intensities are illustrated. 展开更多
关键词 Measles epidemic model Atangana-Baleanu Caputo-Fabrizio differential operators existence and uniqueness qualitative analysis Newton interpolating polynomial
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Remote sensing of air pollution incorporating integrated-path differential-absorption and coherent-Doppler lidar
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作者 Ze-hou Yang Yong Chen +5 位作者 Chun-li Chen Yong-ke Zhang Ji-hui Dong Tao Peng Xiao-feng Li Ding-fu Zhou 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期594-601,共8页
An innovative complex lidar system deployed on an airborne rotorcraft platform for remote sensing of atmospheric pollution is proposed and demonstrated.The system incorporates integrated-path differential absorption l... An innovative complex lidar system deployed on an airborne rotorcraft platform for remote sensing of atmospheric pollution is proposed and demonstrated.The system incorporates integrated-path differential absorption lidar(DIAL) and coherent-doppler lidar(CDL) techniques using a dual tunable TEA CO_(2)laser in the 9—11 μm band and a 1.55 μm fiber laser.By combining the principles of differential absorption detection and pulsed coherent detection,the system enables agile and remote sensing of atmospheric pollution.Extensive static tests validate the system’s real-time detection capabilities,including the measurement of concentration-path-length product(CL),front distance,and path wind speed of air pollution plumes over long distances exceeding 4 km.Flight experiments is conducted with the helicopter.Scanning of the pollutant concentration and the wind field is carried out in an approximately 1 km slant range over scanning angle ranges from 45°to 65°,with a radial resolution of 30 m and10 s.The test results demonstrate the system’s ability to spatially map atmospheric pollution plumes and predict their motion and dispersion patterns,thereby ensuring the protection of public safety. 展开更多
关键词 differential absorption LIDAR COHERENT Doppler lidar Remoting sensing Atmospheric pollution
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KSKV:Key-Strategy for Key-Value Data Collection with Local Differential Privacy
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作者 Dan Zhao Yang You +2 位作者 Chuanwen Luo Ting Chen Yang Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期3063-3083,共21页
In recent years,the research field of data collection under local differential privacy(LDP)has expanded its focus fromelementary data types to includemore complex structural data,such as set-value and graph data.Howev... In recent years,the research field of data collection under local differential privacy(LDP)has expanded its focus fromelementary data types to includemore complex structural data,such as set-value and graph data.However,our comprehensive review of existing literature reveals that there needs to be more studies that engage with key-value data collection.Such studies would simultaneously collect the frequencies of keys and the mean of values associated with each key.Additionally,the allocation of the privacy budget between the frequencies of keys and the means of values for each key does not yield an optimal utility tradeoff.Recognizing the importance of obtaining accurate key frequencies and mean estimations for key-value data collection,this paper presents a novel framework:the Key-Strategy Framework forKey-ValueDataCollection under LDP.Initially,theKey-StrategyUnary Encoding(KS-UE)strategy is proposed within non-interactive frameworks for the purpose of privacy budget allocation to achieve precise key frequencies;subsequently,the Key-Strategy Generalized Randomized Response(KS-GRR)strategy is introduced for interactive frameworks to enhance the efficiency of collecting frequent keys through group-anditeration methods.Both strategies are adapted for scenarios in which users possess either a single or multiple key-value pairs.Theoretically,we demonstrate that the variance of KS-UE is lower than that of existing methods.These claims are substantiated through extensive experimental evaluation on real-world datasets,confirming the effectiveness and efficiency of the KS-UE and KS-GRR strategies. 展开更多
关键词 KEY-VALUE local differential privacy frequency estimation mean estimation data perturbation
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THE EXACT MEROMORPHIC SOLUTIONS OF SOME NONLINEAR DIFFERENTIAL EQUATIONS
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作者 刘慧芳 毛志强 《Acta Mathematica Scientia》 SCIE CSCD 2024年第1期103-114,共12页
We find the exact forms of meromorphic solutions of the nonlinear differential equations■,n≥3,k≥1,where q,Q are nonzero polynomials,Q■Const.,and p_(1),p_(2),α_(1),α_(2)are nonzero constants withα_(1)≠α_(2).Co... We find the exact forms of meromorphic solutions of the nonlinear differential equations■,n≥3,k≥1,where q,Q are nonzero polynomials,Q■Const.,and p_(1),p_(2),α_(1),α_(2)are nonzero constants withα_(1)≠α_(2).Compared with previous results on the equation p(z)f^(3)+q(z)f"=-sinα(z)with polynomial coefficients,our results show that the coefficient of the term f^((k))perturbed by multiplying an exponential function will affect the structure of its solutions. 展开更多
关键词 Nevanlinna theory nonlinear differential equations meromorphic functions entire functions
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Differentially private SGD with random features
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作者 WANG Yi-guang GUO Zheng-chu 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第1期1-23,共23页
In the realm of large-scale machine learning,it is crucial to explore methods for reducing computational complexity and memory demands while maintaining generalization performance.Additionally,since the collected data... In the realm of large-scale machine learning,it is crucial to explore methods for reducing computational complexity and memory demands while maintaining generalization performance.Additionally,since the collected data may contain some sensitive information,it is also of great significance to study privacy-preserving machine learning algorithms.This paper focuses on the performance of the differentially private stochastic gradient descent(SGD)algorithm based on random features.To begin,the algorithm maps the original data into a lowdimensional space,thereby avoiding the traditional kernel method for large-scale data storage requirement.Subsequently,the algorithm iteratively optimizes parameters using the stochastic gradient descent approach.Lastly,the output perturbation mechanism is employed to introduce random noise,ensuring algorithmic privacy.We prove that the proposed algorithm satisfies the differential privacy while achieving fast convergence rates under some mild conditions. 展开更多
关键词 learning theory differential privacy stochastic gradient descent random features reproducing kernel Hilbert spaces
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Value Iteration-Based Cooperative Adaptive Optimal Control for Multi-Player Differential Games With Incomplete Information
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作者 Yun Zhang Lulu Zhang Yunze Cai 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期690-697,共8页
This paper presents a novel cooperative value iteration(VI)-based adaptive dynamic programming method for multi-player differential game models with a convergence proof.The players are divided into two groups in the l... This paper presents a novel cooperative value iteration(VI)-based adaptive dynamic programming method for multi-player differential game models with a convergence proof.The players are divided into two groups in the learning process and adapt their policies sequentially.Our method removes the dependence of admissible initial policies,which is one of the main drawbacks of the PI-based frameworks.Furthermore,this algorithm enables the players to adapt their control policies without full knowledge of others’ system parameters or control laws.The efficacy of our method is illustrated by three examples. 展开更多
关键词 Adaptive dynamic programming incomplete information multi-player differential game value iteration
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Continuous-Time Channel Prediction Based on Tensor Neural Ordinary Differential Equation
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作者 Mingyao Cui Hao Jiang +2 位作者 Yuhao Chen Yang Du Linglong Dai 《China Communications》 SCIE CSCD 2024年第1期163-174,共12页
Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channe... Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channel in a fixed time slot per frame,while the other intra-frame channels are usually recovered by interpolation.However,these approaches suffer from a serious interpolation loss,especially for mobile millimeter-wave communications.To solve this challenging problem,we propose a tensor neural ordinary differential equation(TN-ODE)based continuous-time channel prediction scheme to realize the direct prediction of intra-frame channels.Specifically,inspired by the recently developed continuous mapping model named neural ODE in the field of machine learning,we first utilize the neural ODE model to predict future continuous-time channels.To improve the channel prediction accuracy and reduce computational complexity,we then propose the TN-ODE scheme to learn the structural characteristics of the high-dimensional channel by low-dimensional learnable transform.Simulation results show that the proposed scheme is able to achieve higher intra-frame channel prediction accuracy than existing schemes. 展开更多
关键词 channel prediction massive multipleinput-multiple-output millimeter-wave communications ordinary differential equation
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A Coupled Thermomechanical Crack Propagation Behavior of Brittle Materials by Peridynamic Differential Operator
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作者 Tianyi Li Xin Gu Qing Zhang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第7期339-361,共23页
This study proposes a comprehensive,coupled thermomechanical model that replaces local spatial derivatives in classical differential thermomechanical equations with nonlocal integral forms derived from the peridynamic... This study proposes a comprehensive,coupled thermomechanical model that replaces local spatial derivatives in classical differential thermomechanical equations with nonlocal integral forms derived from the peridynamic differential operator(PDDO),eliminating the need for calibration procedures.The model employs a multi-rate explicit time integration scheme to handle varying time scales in multi-physics systems.Through simulations conducted on granite and ceramic materials,this model demonstrates its effectiveness.It successfully simulates thermal damage behavior in granite arising from incompatible mineral expansion and accurately calculates thermal crack propagation in ceramic slabs during quenching.To account for material heterogeneity,the model utilizes the Shuffle algorithm andWeibull distribution,yielding results that align with numerical simulations and experimental observations.This coupled thermomechanical model shows great promise for analyzing intricate thermomechanical phenomena in brittle materials. 展开更多
关键词 Peridynamic differential operator thermomechanical coupling HETEROGENEITY numerical simulation
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Operational optimization of copper flotation process based on the weighted Gaussian process regression and index-oriented adaptive differential evolution algorithm
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作者 Zhiqiang Wang Dakuo He Haotian Nie 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第2期167-179,共13页
Concentrate copper grade(CCG)is one of the important production indicators of copper flotation processes,and keeping the CCG at the set value is of great significance to the economic benefit of copper flotation indust... Concentrate copper grade(CCG)is one of the important production indicators of copper flotation processes,and keeping the CCG at the set value is of great significance to the economic benefit of copper flotation industrial processes.This paper addresses the fluctuation problem of CCG through an operational optimization method.Firstly,a density-based affinity propagationalgorithm is proposed so that more ideal working condition categories can be obtained for the complex raw ore properties.Next,a Bayesian network(BN)is applied to explore the relationship between the operational variables and the CCG.Based on the analysis results of BN,a weighted Gaussian process regression model is constructed to predict the CCG that a higher prediction accuracy can be obtained.To ensure the predicted CCG is close to the set value with a smaller magnitude of the operation adjustments and a smaller uncertainty of the prediction results,an index-oriented adaptive differential evolution(IOADE)algorithm is proposed,and the convergence performance of IOADE is superior to the traditional differential evolution and adaptive differential evolution methods.Finally,the effectiveness and feasibility of the proposed methods are verified by the experiments on a copper flotation industrial process. 展开更多
关键词 Weighted Gaussian process regression Index-oriented adaptive differential evolution Operational optimization Copper flotation process
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Deep Structure Optimization for Incremental Hierarchical Fuzzy Systems Using Improved Differential Evolution Algorithm
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作者 Yue Zhu Tao Zhao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1139-1158,共20页
The optimization of the rule base of a fuzzy logic system (FLS) based on evolutionary algorithm has achievednotable results. However, due to the diversity of the deep structure in the hierarchical fuzzy system (HFS) a... The optimization of the rule base of a fuzzy logic system (FLS) based on evolutionary algorithm has achievednotable results. However, due to the diversity of the deep structure in the hierarchical fuzzy system (HFS) and thecorrelation of each sub fuzzy system, the uncertainty of the HFS’s deep structure increases. For the HFS, a largenumber of studies mainly use fixed structures, which cannot be selected automatically. To solve this problem, thispaper proposes a novel approach for constructing the incremental HFS. During system design, the deep structureand the rule base of the HFS are encoded separately. Subsequently, the deep structure is adaptively mutated basedon the fitness value, so as to realize the diversity of deep structures while ensuring reasonable competition amongthe structures. Finally, the differential evolution (DE) is used to optimize the deep structure of HFS and theparameters of antecedent and consequent simultaneously. The simulation results confirm the effectiveness of themodel. Specifically, the root mean square errors in the Laser dataset and Friedman dataset are 0.0395 and 0.0725,respectively with rule counts of rules is 8 and 12, respectively.When compared to alternative methods, the resultsindicate that the proposed method offers improvements in accuracy and rule counts. 展开更多
关键词 Hierarchical fuzzy system automatic optimization differential evolution regression problem
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Results Involving Partial Differential Equations and Their Solution by Certain Integral Transform
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作者 Rania Saadah Mohammed Amleh +2 位作者 Ahmad Qazza Shrideh Al-Omari Ahmet Ocak Akdemir 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1593-1616,共24页
In this study,we aimto investigate certain triple integral transformand its application to a class of partial differentialequations.We discuss various properties of the new transformincluding inversion, linearity, exi... In this study,we aimto investigate certain triple integral transformand its application to a class of partial differentialequations.We discuss various properties of the new transformincluding inversion, linearity, existence, scaling andshifting, etc. Then,we derive several results enfolding partial derivatives and establish amulti-convolution theorem.Further, we apply the aforementioned transform to some classical functions and many types of partial differentialequations involving heat equations,wave equations, Laplace equations, and Poisson equations aswell.Moreover,wedraw some figures to illustrate 3-D contour plots for exact solutions of some selected examples involving differentvalues in their variables. 展开更多
关键词 ARA transform double ARA transform triple ARA transform partial differential equations integral transform
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A Differential Privacy Federated Learning Scheme Based on Adaptive Gaussian Noise
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作者 Sanxiu Jiao Lecai Cai +2 位作者 Xinjie Wang Kui Cheng Xiang Gao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1679-1694,共16页
As a distributed machine learning method,federated learning(FL)has the advantage of naturally protecting data privacy.It keeps data locally and trains local models through local data to protect the privacy of local da... As a distributed machine learning method,federated learning(FL)has the advantage of naturally protecting data privacy.It keeps data locally and trains local models through local data to protect the privacy of local data.The federated learning method effectively solves the problem of artificial Smart data islands and privacy protection issues.However,existing research shows that attackersmay still steal user information by analyzing the parameters in the federated learning training process and the aggregation parameters on the server side.To solve this problem,differential privacy(DP)techniques are widely used for privacy protection in federated learning.However,adding Gaussian noise perturbations to the data degrades the model learning performance.To address these issues,this paper proposes a differential privacy federated learning scheme based on adaptive Gaussian noise(DPFL-AGN).To protect the data privacy and security of the federated learning training process,adaptive Gaussian noise is specifically added in the training process to hide the real parameters uploaded by the client.In addition,this paper proposes an adaptive noise reduction method.With the convergence of the model,the Gaussian noise in the later stage of the federated learning training process is reduced adaptively.This paper conducts a series of simulation experiments on realMNIST and CIFAR-10 datasets,and the results show that the DPFL-AGN algorithmperforms better compared to the other algorithms. 展开更多
关键词 differential privacy federated learning deep learning data privacy
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Differential diagnosis of Crohn’s disease and intestinal tuberculosis based on ATR-FTIR spectroscopy combined with machine learning
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作者 Yuan-Peng Li Tian-Yu Lu +5 位作者 Fu-Rong Huang Wei-Min Zhang Zhen-Qiang Chen Pei-Wen Guang Liang-Yu Deng Xin-Hao Yang 《World Journal of Gastroenterology》 SCIE CAS 2024年第10期1377-1392,共16页
BACKGROUND Crohn’s disease(CD)is often misdiagnosed as intestinal tuberculosis(ITB).However,the treatment and prognosis of these two diseases are dramatically different.Therefore,it is important to develop a method t... BACKGROUND Crohn’s disease(CD)is often misdiagnosed as intestinal tuberculosis(ITB).However,the treatment and prognosis of these two diseases are dramatically different.Therefore,it is important to develop a method to identify CD and ITB with high accuracy,specificity,and speed.AIM To develop a method to identify CD and ITB with high accuracy,specificity,and speed.METHODS A total of 72 paraffin wax-embedded tissue sections were pathologically and clinically diagnosed as CD or ITB.Paraffin wax-embedded tissue sections were attached to a metal coating and measured using attenuated total reflectance fourier transform infrared spectroscopy at mid-infrared wavelengths combined with XGBoost for differential diagnosis.RESULTS The results showed that the paraffin wax-embedded specimens of CD and ITB were significantly different in their spectral signals at 1074 cm^(-1) and 1234 cm^(-1) bands,and the differential diagnosis model based on spectral characteristics combined with machine learning showed accuracy,specificity,and sensitivity of 91.84%,92.59%,and 90.90%,respectively,for the differential diagnosis of CD and ITB.CONCLUSION Information on the mid-infrared region can reveal the different histological components of CD and ITB at the molecular level,and spectral analysis combined with machine learning to establish a diagnostic model is expected to become a new method for the differential diagnosis of CD and ITB. 展开更多
关键词 Infrared spectroscopy Machine learning Intestinal tuberculosis Crohn’s disease differential diagnosis Inflammatory bowel disease
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Euler’s First-Order Explicit Method–Peridynamic Differential Operator for Solving Population Balance Equations of the Crystallization Process
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作者 Chunlei Ruan Cengceng Dong +2 位作者 Kunfeng Liang Zhijun Liu Xinru Bao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期3033-3049,共17页
Using Euler’s first-order explicit(EE)method and the peridynamic differential operator(PDDO)to discretize the time and internal crystal-size derivatives,respectively,the Euler’s first-order explicit method–peridyna... Using Euler’s first-order explicit(EE)method and the peridynamic differential operator(PDDO)to discretize the time and internal crystal-size derivatives,respectively,the Euler’s first-order explicit method–peridynamic differential operator(EE–PDDO)was obtained for solving the one-dimensional population balance equation in crystallization.Four different conditions during crystallization were studied:size-independent growth,sizedependent growth in a batch process,nucleation and size-independent growth,and nucleation and size-dependent growth in a continuous process.The high accuracy of the EE–PDDO method was confirmed by comparing it with the numerical results obtained using the second-order upwind and HR-van methods.The method is characterized by non-oscillation and high accuracy,especially in the discontinuous and sharp crystal size distribution.The stability of the EE–PDDO method,choice of weight function in the PDDO method,and optimal time step are also discussed. 展开更多
关键词 Population balance equation CRYSTALLIZATION peridynamic differential operator Euler’s first-order explicit method
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Strengthened Dominance Relation NSGA-Ⅲ Algorithm Based on Differential Evolution to Solve Job Shop Scheduling Problem
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作者 Liang Zeng Junyang Shi +2 位作者 Yanyan Li Shanshan Wang Weigang Li 《Computers, Materials & Continua》 SCIE EI 2024年第1期375-392,共18页
The job shop scheduling problem is a classical combinatorial optimization challenge frequently encountered in manufacturing systems.It involves determining the optimal execution sequences for a set of jobs on various ... The job shop scheduling problem is a classical combinatorial optimization challenge frequently encountered in manufacturing systems.It involves determining the optimal execution sequences for a set of jobs on various machines to maximize production efficiency and meet multiple objectives.The Non-dominated Sorting Genetic Algorithm Ⅲ(NSGA-Ⅲ)is an effective approach for solving the multi-objective job shop scheduling problem.Nevertheless,it has some limitations in solving scheduling problems,including inadequate global search capability,susceptibility to premature convergence,and challenges in balancing convergence and diversity.To enhance its performance,this paper introduces a strengthened dominance relation NSGA-Ⅲ algorithm based on differential evolution(NSGA-Ⅲ-SD).By incorporating constrained differential evolution and simulated binary crossover genetic operators,this algorithm effectively improves NSGA-Ⅲ’s global search capability while mitigating pre-mature convergence issues.Furthermore,it introduces a reinforced dominance relation to address the trade-off between convergence and diversity in NSGA-Ⅲ.Additionally,effective encoding and decoding methods for discrete job shop scheduling are proposed,which can improve the overall performance of the algorithm without complex computation.To validate the algorithm’s effectiveness,NSGA-Ⅲ-SD is extensively compared with other advanced multi-objective optimization algorithms using 20 job shop scheduling test instances.The experimental results demonstrate that NSGA-Ⅲ-SD achieves better solution quality and diversity,proving its effectiveness in solving the multi-objective job shop scheduling problem. 展开更多
关键词 Multi-objective job shop scheduling non-dominated sorting genetic algorithm differential evolution simulated binary crossover
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Identification of differentially expressed mRNAs as novel predictive biomarkers for gastric cancer diagnosis and prognosis
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作者 Jian-Wei Zhou Yi-Bing Zhang +2 位作者 Zhi-Yang Huang Yu-Ping Yuan Jie Jin 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第5期1947-1964,共18页
BACKGROUND Gastric cancer(GC)has a high mortality rate worldwide.Despite significant progress in GC diagnosis and treatment,the prognosis for affected patients still remains unfavorable.AIM To identify important candi... BACKGROUND Gastric cancer(GC)has a high mortality rate worldwide.Despite significant progress in GC diagnosis and treatment,the prognosis for affected patients still remains unfavorable.AIM To identify important candidate genes related to the development of GC and iden-tify potential pathogenic mechanisms through comprehensive bioinformatics analysis.METHODS The Gene Expression Omnibus database was used to obtain the GSE183136 dataset,which includes a total of 135 GC samples.The limma package in R software was employed to identify differentially expressed genes(DEGs).Thereafter,enrichment analyses of Gene Ontology(GO)terms and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways were performed for the gene modules using the clusterProfile package in R software.The protein-protein interaction(PPI)networks of target genes were constructed using STRING and visualized by Cytoscape software.The common hub genes that emerged in the cohort of DEGs that was retrieved from the GEPIA database were then screened using a Venn Diagram.The expression levels of these overlapping genes in stomach adenocarcinoma samples and non-tumor samples and their association with prognosis in GC patients were also obtained from the GEPIA database and Kaplan-Meier curves.Moreover,real-time quantitative polymerase chain reaction(RT-qPCR)and western blotting were performed to determine the mRNA and protein levels of glutamic-pyruvic transaminase(GPT)in GC and normal immortalized cell lines.In addition,cell viability,cell cycle distribution,migration and invasion were evaluated by cell counting kit-8,flow cytometry and transwell assays.Furthermore,we also conducted a retrospective analysis on 70 GC patients diagnosed and surgically treated in Wenzhou Central Hospital,Dingli Clinical College of Wenzhou Medical University,The Second Affiliated Hospital of Shanghai University between January 2017 to December 2020.The tumor and adjacent normal samples were collected from the patients to determine the potential association between the expression level of GPT and the clinical as well as pathological features of GC patients.RESULTS We selected 19214 genes from the GSE183136 dataset,among which there were 250 downregulated genes and 401 upregulated genes in the tumor samples of stage III-IV in comparison to those in tumor samples of stage I-II with a P-value<0.05.In addition,GO and KEGG results revealed that the various upregulated DEGs were mainly enriched in plasma membrane and neuroactive ligand-receptor interaction,whereas the downregulated DEGs were primarily enriched in cytosol and pancreatic secretion,vascular smooth muscle contraction and biosynthesis of the different cofactors.Furthermore,PPI networks were constructed based on the various upregulated and downregulated genes,and there were a total 15 upregulated and 10 downregulated hub genes.After a comprehensive analysis,several hub genes,including runt-related transcription factor 2(RUNX2),salmonella pathogenicity island 1(SPI1),lysyl oxidase(LOX),fibrillin 1(FBN1)and GPT,displayed prognostic values.Interestingly,it was observed that GPT was downregulated in GC cells and its upregulation could suppress the malignant phenotypes of GC cells.Furthermore,the expression level of GPT was found to be associated with age,lymph node metastasis,pathological staging and distant metastasis(P<0.05).CONCLUSION RUNX2,SPI1,LOX,FBN1 and GPT were identified key hub genes in GC by bioinformatics analysis.GPT was significantly associated with the prognosis of GC,and its upregulation can effectively inhibit the proliferative,migrative and invasive capabilities of GC cells. 展开更多
关键词 Gastric cancer differentially expressed genes BIOINFORMATICS Hub genes Prognosis
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Differential pressure difference based altitude control of a stratospheric satellite
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作者 陈丽 WANG Xiaoliang 《High Technology Letters》 EI CAS 2024年第1期1-12,共12页
An autonomous altitude adjustment system for a stratospheric satellite(StratoSat)platform is proposed.This platform consists of a helium balloon,a ballonet,and a two-way blower.The helium balloon generates lift to bal... An autonomous altitude adjustment system for a stratospheric satellite(StratoSat)platform is proposed.This platform consists of a helium balloon,a ballonet,and a two-way blower.The helium balloon generates lift to balance the platform gravity.The two-way blower inflates and deflates the ballonet to regulate the buoyancy.Altitude adjustment is achieved by tracking the differential pressure difference(DPD),and a threshold switching strategy is used to achieve blower flow control.The vertical acceleration regulation ability is decided not only by the blower flow rate,but also by the designed margin of pressure difference(MPD).Pressure difference is a slow-varying variable compared with altitude,and it is adopted as the control variable.The response speed of the actuator to disturbance can be delayed,and the overshoot caused by the large inertia of the platform is inhibited.This method can maintain a high tracking accuracy and reduce the complexity of model calculation,thus improving the robustness of controller design. 展开更多
关键词 stratospheric satellite(StratoSat) differential pressure difference(DPD) altitude adjustment threshold switching strategy margin of pressure difference(MPD)
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Research on Carbon Emission for Preventive Maintenance of Wind Turbine Gearbox Based on Stochastic Differential Equation
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作者 Hongsheng Su Lixia Dong +1 位作者 Xiaoying Yu Kai Liu 《Energy Engineering》 EI 2024年第4期973-986,共14页
Time based maintenance(TBM)and condition based maintenance(CBM)are widely applied in many large wind farms to optimize the maintenance issues of wind turbine gearboxes,however,these maintenance strategies do not take ... Time based maintenance(TBM)and condition based maintenance(CBM)are widely applied in many large wind farms to optimize the maintenance issues of wind turbine gearboxes,however,these maintenance strategies do not take into account environmental benefits during full life cycle such as carbon emissions issues.Hence,this article proposes a carbon emissions computing model for preventive maintenance activities of wind turbine gearboxes to solve the issue.Based on the change of the gearbox state during operation and the influence of external random factors on the gearbox state,a stochastic differential equation model(SDE)and corresponding carbon emission model are established,wherein SDE is applied to model the evolution of the device state,whereas carbon emission is used to implement carbon emissions computing.The simulation results indicate that the proposed preventive maintenance cannot ensure reliable operation of wind turbine gearboxes but reduce carbon emissions during their lifespan.Compared with TBM,CBM minimizes unit carbon emissions without influencing reliable operation,making it an effective maintenance method. 展开更多
关键词 Stochastic differential equation(SDE) condition-based maintenance(CBM) carbon emissions
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How Group Leaders Build Stable Community Buying Groups:A Perspective Based on the Differential Mode of Association
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作者 SI Xiang 《Psychology Research》 2024年第1期30-35,共6页
Since 2016,community group buying has grown significantly in China,largely driven by its efficient logistics,supply chains,low prices,and convenience.This model has been further popularized during the COVID-19 pandemi... Since 2016,community group buying has grown significantly in China,largely driven by its efficient logistics,supply chains,low prices,and convenience.This model has been further popularized during the COVID-19 pandemic due to its effectiveness in meeting daily needs while minimizing human-to-human contact.A key component of this business model is the“group leaders”-influential individuals within a community responsible for managing group buying activities,which include order collection,supplier liaison,and goods distribution.Their primary task is to form and sustain a reliable community group buying consortium,a task that demands excellent organizational and interpersonal skills.This paper examines this phenomenon using the lens of the differential mode of association,a theoretical model explaining interpersonal relationships in traditional Chinese society.The research indicates that group leaders,through regular interaction with consumers,are able to alter their social network position,increase their influence,understand consumer needs,provide satisfying services,and enhance trust,thereby transforming consumers into loyal group buying participants.This transformation not only brings stability to group buying activities but also reinforces the community influence of group leaders,thus fostering the growth of community group buying. 展开更多
关键词 Community group buying China Group leaders The differential mode of association
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Decoding Retinoblastoma: Differential Gene Expression
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作者 Ahmed Jasim Mahmood Al-Mashhadani Franko Shehaj Lianhong Zhou 《International Journal of Clinical Medicine》 CAS 2024年第4期177-196,共20页
Background: Retinoblastoma, the most common intraocular pediatric cancer, presents complexities in its genetic landscape that necessitate a deeper understanding for improved therapeutic interventions. This study lever... Background: Retinoblastoma, the most common intraocular pediatric cancer, presents complexities in its genetic landscape that necessitate a deeper understanding for improved therapeutic interventions. This study leverages computational tools to dissect the differential gene expression profiles in retinoblastoma. Methods: Employing an in silico approach, we analyzed gene expression data from public repositories by applying rigorous statistical models, including limma and de seq 2, for identifying differentially expressed genes DEGs. Our findings were validated through cross-referencing with independent datasets and existing literature. We further employed functional annotation and pathway analysis to elucidate the biological significance of these DEGs. Results: Our computational analysis confirmed the dysregulation of key retinoblastoma-associated genes. In comparison to normal retinal tissue, RB1 exhibited a 2.5-fold increase in expression (adjusted p Conclusions: Our analysis reinforces the critical genetic alterations known in retinoblastoma and unveils new avenues for research into the disease’s molecular basis. The discovery of chemoresistance markers and immune-related genes opens potential pathways for personalized treatment strategies. The study’s outcomes emphasize the power of in silico analyses in unraveling complex cancer genomics. 展开更多
关键词 Retinoblastoma Gene Expression In Silico Study differentially Expressed Genes CHEMORESISTANCE Immune Response Computational Biology
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