Objective:To observe changes in RBC count,changes,RBC morphology,and serum potassium during compressed transfusion of WBC-removal whole blood.Methods:Prepared human WBC-removal whole blood and connected transfusion ap...Objective:To observe changes in RBC count,changes,RBC morphology,and serum potassium during compressed transfusion of WBC-removal whole blood.Methods:Prepared human WBC-removal whole blood and connected transfusion apparatus with different sizes of intravenous detaining needles(18G,20 G,22G and 24G).Observed RBC count and serum potassium concentration under different pressures(100 mmHg,200 mmHg,and 300 mmHg)as blood flowed out of the pinhead end of the intravenous detaining needle.Samples obtained with the 20 G needle were smeared on glass slides,and RBC morphologic changes were observed under an oil immersion lens.Results:RBC count and serum potassium changed slightly under different pressures with different sizes of intravenous detaining needles as blood flowed through the transfusion apparatus.In addition,the observation of blood samples under a common light microscope revealed that coarse-prick,oblong,and spindle cell counts in the visual fields increased gradually as the pressure increased.Additionally,aportion of cells had undergone splintering.Conclusions:While applying 18 G,20G,22 G and 24 G intravenous detaining needles for blood transfusion under less than 300 mmHg of pressure,no significant RBC count change was found in blood samples in the short term.However,there were significant RBC morphologic changes.The results could offer more basis to ensure the clinical safety of patients undergoing blood transfusion.展开更多
This is a prospective and descriptive study carried out at the gynecology and obstetrics department of the reference health center of Fana from 01 May 2019 to 30 November or 7 months. The main objective was to study t...This is a prospective and descriptive study carried out at the gynecology and obstetrics department of the reference health center of Fana from 01 May 2019 to 30 November or 7 months. The main objective was to study the role of blood transfusion in the management of obstetric emergencies. During the study period we recorded 434 cases of obstetric emergencies of which 116 cases required an emergency blood transfusion or 26.73%. The most frequently found indications for blood transfusion are hemorrhages of the immediate postpartum 46.6% followed by severe malaria on pregnancy 27.6%. Blood remains the most prescribed and available Labile blood product in the department. Maternal prognosis was improved in 92.2%.展开更多
目的了解复方电解质注射液洗涤的术中回收(IBS)红细胞回输患者时间<3 d血浆Hb及RBC的变化情况。方法选择46名择期行骨科手术且做IBS的患者,分别以生理盐水(NS组,n=24)和复方电解质液(MEI组,n=22)洗涤IBS红细胞,于术前、术(输)后即刻...目的了解复方电解质注射液洗涤的术中回收(IBS)红细胞回输患者时间<3 d血浆Hb及RBC的变化情况。方法选择46名择期行骨科手术且做IBS的患者,分别以生理盐水(NS组,n=24)和复方电解质液(MEI组,n=22)洗涤IBS红细胞,于术前、术(输)后即刻、术(输)后1-3 d取2组患者静脉血2 mL/人(份),检测Hb、RBC并记录术中2组失血量、回收红细胞净输入量和术后引流量等。结果2组患者术前一般情况、手术时间、回收红细胞离体时间、术中失血量、回收红细胞净输入量相近(P>0.05)。术前、术(输)后即刻及术(输)后1-3 d Hb(g/L),组内比较:NS组术前vs术(输)后即刻为121.4±14.5 vs 109.0±18.3、术(输)后1 d vs术(输)后2 d为110.0±16.7 vs 102.8±17.7、术(输)后2-3 d vs术(输)后即刻为102.8±17.7 vs 101.7±15.6 vs 109.0±18.3(P<0.01);术(输)后即刻vs术(输)后1 d为109.0±18.3 vs 110.0±16.7、术(输)后2 d vs术(输)后3 d为102.8±17.7 vs 101.7±15.6(P>0.05),MEI组术前vs术(输)后即刻为127.3±14.0 vs 112.0±14.4、术后(输)即刻vs术(输)后1 d为112.0±14.4 vs 119.8±15.7、术(输)后1 d vs术(输)后2 d为119.8±15.7 vs 106.6±16.3(P<0.01);术(输)后2 d vs术(输)后3 d为106.6±16.3 vs 107.3±15.0、术(输)后2-3 d vs术(输)后即刻为106.6±16.3 vs 107.3±15.0 vs 112.0±14.4(P>0.05);组间比较:NS与MEI组术(输)后1 d为110.0±16.7 vs 119.8±15.7(P<0.05)、其余时间的检测值2组相近(P>0.05)。术前、术(输)后即刻、术(输)后1-3 d RBC(×10^9/L),组内比较:NS组分别为术前vs术(输)后即刻为3.91±0.49 vs 3.52±0.63、术(输)1 d vs术(输)2 d为3.56±0.59 vs 3.31±0.56、术(输)后2-3 d vs术(输)后即刻为3.31±0.56 vs 3.30±0.53 vs 3.52±0.63(P<0.01);术(输)后即刻vs术(输)后1 d为3.52±0.63 vs 3.56±0.59、术(输)后2 d vs术(输)后3 d为3.31±0.56 vs 3.30±0.53(P>0.05),MEI组分别为术前vs术(输)后即刻为4.13±0.43 vs 3.67±0.47、术(输)后即刻vs术(输)1 d为3.67±0.47 vs 3.92±0.55、术(输)后1 d vs术(输)2 d后为3.92±0.55 vs 3.53±0.55(P<0.01),术(输)后2 d vs术(输)后3 d为3.53±0.55 vs 3.56±0.50、术(输)后2-3 d vs术(输)后即刻为3.53±0.55 vs 3.56±0.50 vs 3.67±0.47(P>0.05),组间比较:NS与MEI组术(输)后1 d为3.56±0.59 vs 3.92±0.55(P<0.05),其余时间的检测值2组相近(P>0.05)。结论复方电解质注射液可以延缓IBS红细胞回输体内后患者Hb和RBC下降速度。展开更多
目的调查儿科急诊非急诊手术患儿输血后红细胞恢复的影响因素。方法回顾2020年1月—2020年12月期间广州市妇女儿童医疗中心珠江新城院区儿科急诊1月~18岁患儿的输血情况,其中分为Hb提升达预期组(n=93),Hb提升未达预期组(n=156),根据年...目的调查儿科急诊非急诊手术患儿输血后红细胞恢复的影响因素。方法回顾2020年1月—2020年12月期间广州市妇女儿童医疗中心珠江新城院区儿科急诊1月~18岁患儿的输血情况,其中分为Hb提升达预期组(n=93),Hb提升未达预期组(n=156),根据年龄、性别、体质量、是否恶性肿瘤、是否发热、有无延迟输血、输血前血红蛋白水平、输注红细胞类型情况,分析输血疗效及影响因素。结果2组患儿的性别、年龄、体质量、有无恶性肿瘤、是否发热、输血等待时间、输血前后血红蛋白值、输注红细胞悬液量以及有无及时输血均无统计学差异;输注红细胞类型组间存在显著差异,Hb提升未达预期组更多输注了洗涤红细胞悬液(13.5%vs 5.4%,P=0.044),输血后Hb值较低(中位数,73 g/L vs 84 g/L,P<0.001),变化Hb值较小(中位数,18 g/L vs 30 g/L,P<0.001),归因分析未发现影响因素。结论输注洗涤红细胞可能是降低输血后红细胞提升的影响因素,输注洗涤红细胞时需严格输血指征同时注意红细胞提高预值的设定。展开更多
目的探讨1种改良限制性输血策略指导急诊患者围术期RBC输注的安全性、可行性及临床价值。方法将急诊需输血的成年患者47名,随机分为实验组(以改良的输血策略指导临床输血,n=23)和对照组(医生依据《临床输血技术规范》按经验进行临床输血...目的探讨1种改良限制性输血策略指导急诊患者围术期RBC输注的安全性、可行性及临床价值。方法将急诊需输血的成年患者47名,随机分为实验组(以改良的输血策略指导临床输血,n=23)和对照组(医生依据《临床输血技术规范》按经验进行临床输血,n=24),记录:1)估计失血量、手术时间、术中补液、麻醉后恢复室停留时间及住院时间,术后2、6、12、24、48、72 h及急诊住院结束各时间点的HR、MAP、T,入院、入室、出室、术后24 h、术后72 h及住院结束时Hb的变化;2)输血相关并发症及死亡率;3)RBC输注情况,围术期自体或/和异体RBC输注率与人均输注量。结果实验组与对照组患者估计失血量、手术时间、术中补液、PACU停留时间及住院时间相近(P>0.05),术后各观察时间点的HR、MAP及T比较差异甚小(P>0.05);出室及术后24 h Hb(g/L),分别为90.31±11.40 vs 100.88±16.75(P<0.05),入院、入室、术后72 h及急诊住院时Hb相近(P>0.05);2组均无输血相关不良反应及死亡病例发生。异体RBC输注率56.52%(13/23)vs 91.66%(22/24)(P<0.05);人均输血量(U)分别为2.00±2.41 vs 6.04±5.48(P<0.05),已输血患者异体红细胞的人均输注量(U)3.53±2.18 vs 6.59±5.4(P<0.05)。结论采用本研究所涉改良限制性输血策略或可更安全、有效指导临床急诊输血,值得临床进一步研究。展开更多
基金supported by the Shanxi Science and Technology Development Fund(No.200233)
文摘Objective:To observe changes in RBC count,changes,RBC morphology,and serum potassium during compressed transfusion of WBC-removal whole blood.Methods:Prepared human WBC-removal whole blood and connected transfusion apparatus with different sizes of intravenous detaining needles(18G,20 G,22G and 24G).Observed RBC count and serum potassium concentration under different pressures(100 mmHg,200 mmHg,and 300 mmHg)as blood flowed out of the pinhead end of the intravenous detaining needle.Samples obtained with the 20 G needle were smeared on glass slides,and RBC morphologic changes were observed under an oil immersion lens.Results:RBC count and serum potassium changed slightly under different pressures with different sizes of intravenous detaining needles as blood flowed through the transfusion apparatus.In addition,the observation of blood samples under a common light microscope revealed that coarse-prick,oblong,and spindle cell counts in the visual fields increased gradually as the pressure increased.Additionally,aportion of cells had undergone splintering.Conclusions:While applying 18 G,20G,22 G and 24 G intravenous detaining needles for blood transfusion under less than 300 mmHg of pressure,no significant RBC count change was found in blood samples in the short term.However,there were significant RBC morphologic changes.The results could offer more basis to ensure the clinical safety of patients undergoing blood transfusion.
文摘This is a prospective and descriptive study carried out at the gynecology and obstetrics department of the reference health center of Fana from 01 May 2019 to 30 November or 7 months. The main objective was to study the role of blood transfusion in the management of obstetric emergencies. During the study period we recorded 434 cases of obstetric emergencies of which 116 cases required an emergency blood transfusion or 26.73%. The most frequently found indications for blood transfusion are hemorrhages of the immediate postpartum 46.6% followed by severe malaria on pregnancy 27.6%. Blood remains the most prescribed and available Labile blood product in the department. Maternal prognosis was improved in 92.2%.
文摘目的了解复方电解质注射液洗涤的术中回收(IBS)红细胞回输患者时间<3 d血浆Hb及RBC的变化情况。方法选择46名择期行骨科手术且做IBS的患者,分别以生理盐水(NS组,n=24)和复方电解质液(MEI组,n=22)洗涤IBS红细胞,于术前、术(输)后即刻、术(输)后1-3 d取2组患者静脉血2 mL/人(份),检测Hb、RBC并记录术中2组失血量、回收红细胞净输入量和术后引流量等。结果2组患者术前一般情况、手术时间、回收红细胞离体时间、术中失血量、回收红细胞净输入量相近(P>0.05)。术前、术(输)后即刻及术(输)后1-3 d Hb(g/L),组内比较:NS组术前vs术(输)后即刻为121.4±14.5 vs 109.0±18.3、术(输)后1 d vs术(输)后2 d为110.0±16.7 vs 102.8±17.7、术(输)后2-3 d vs术(输)后即刻为102.8±17.7 vs 101.7±15.6 vs 109.0±18.3(P<0.01);术(输)后即刻vs术(输)后1 d为109.0±18.3 vs 110.0±16.7、术(输)后2 d vs术(输)后3 d为102.8±17.7 vs 101.7±15.6(P>0.05),MEI组术前vs术(输)后即刻为127.3±14.0 vs 112.0±14.4、术后(输)即刻vs术(输)后1 d为112.0±14.4 vs 119.8±15.7、术(输)后1 d vs术(输)后2 d为119.8±15.7 vs 106.6±16.3(P<0.01);术(输)后2 d vs术(输)后3 d为106.6±16.3 vs 107.3±15.0、术(输)后2-3 d vs术(输)后即刻为106.6±16.3 vs 107.3±15.0 vs 112.0±14.4(P>0.05);组间比较:NS与MEI组术(输)后1 d为110.0±16.7 vs 119.8±15.7(P<0.05)、其余时间的检测值2组相近(P>0.05)。术前、术(输)后即刻、术(输)后1-3 d RBC(×10^9/L),组内比较:NS组分别为术前vs术(输)后即刻为3.91±0.49 vs 3.52±0.63、术(输)1 d vs术(输)2 d为3.56±0.59 vs 3.31±0.56、术(输)后2-3 d vs术(输)后即刻为3.31±0.56 vs 3.30±0.53 vs 3.52±0.63(P<0.01);术(输)后即刻vs术(输)后1 d为3.52±0.63 vs 3.56±0.59、术(输)后2 d vs术(输)后3 d为3.31±0.56 vs 3.30±0.53(P>0.05),MEI组分别为术前vs术(输)后即刻为4.13±0.43 vs 3.67±0.47、术(输)后即刻vs术(输)1 d为3.67±0.47 vs 3.92±0.55、术(输)后1 d vs术(输)2 d后为3.92±0.55 vs 3.53±0.55(P<0.01),术(输)后2 d vs术(输)后3 d为3.53±0.55 vs 3.56±0.50、术(输)后2-3 d vs术(输)后即刻为3.53±0.55 vs 3.56±0.50 vs 3.67±0.47(P>0.05),组间比较:NS与MEI组术(输)后1 d为3.56±0.59 vs 3.92±0.55(P<0.05),其余时间的检测值2组相近(P>0.05)。结论复方电解质注射液可以延缓IBS红细胞回输体内后患者Hb和RBC下降速度。
文摘目的调查儿科急诊非急诊手术患儿输血后红细胞恢复的影响因素。方法回顾2020年1月—2020年12月期间广州市妇女儿童医疗中心珠江新城院区儿科急诊1月~18岁患儿的输血情况,其中分为Hb提升达预期组(n=93),Hb提升未达预期组(n=156),根据年龄、性别、体质量、是否恶性肿瘤、是否发热、有无延迟输血、输血前血红蛋白水平、输注红细胞类型情况,分析输血疗效及影响因素。结果2组患儿的性别、年龄、体质量、有无恶性肿瘤、是否发热、输血等待时间、输血前后血红蛋白值、输注红细胞悬液量以及有无及时输血均无统计学差异;输注红细胞类型组间存在显著差异,Hb提升未达预期组更多输注了洗涤红细胞悬液(13.5%vs 5.4%,P=0.044),输血后Hb值较低(中位数,73 g/L vs 84 g/L,P<0.001),变化Hb值较小(中位数,18 g/L vs 30 g/L,P<0.001),归因分析未发现影响因素。结论输注洗涤红细胞可能是降低输血后红细胞提升的影响因素,输注洗涤红细胞时需严格输血指征同时注意红细胞提高预值的设定。
文摘目的探讨1种改良限制性输血策略指导急诊患者围术期RBC输注的安全性、可行性及临床价值。方法将急诊需输血的成年患者47名,随机分为实验组(以改良的输血策略指导临床输血,n=23)和对照组(医生依据《临床输血技术规范》按经验进行临床输血,n=24),记录:1)估计失血量、手术时间、术中补液、麻醉后恢复室停留时间及住院时间,术后2、6、12、24、48、72 h及急诊住院结束各时间点的HR、MAP、T,入院、入室、出室、术后24 h、术后72 h及住院结束时Hb的变化;2)输血相关并发症及死亡率;3)RBC输注情况,围术期自体或/和异体RBC输注率与人均输注量。结果实验组与对照组患者估计失血量、手术时间、术中补液、PACU停留时间及住院时间相近(P>0.05),术后各观察时间点的HR、MAP及T比较差异甚小(P>0.05);出室及术后24 h Hb(g/L),分别为90.31±11.40 vs 100.88±16.75(P<0.05),入院、入室、术后72 h及急诊住院时Hb相近(P>0.05);2组均无输血相关不良反应及死亡病例发生。异体RBC输注率56.52%(13/23)vs 91.66%(22/24)(P<0.05);人均输血量(U)分别为2.00±2.41 vs 6.04±5.48(P<0.05),已输血患者异体红细胞的人均输注量(U)3.53±2.18 vs 6.59±5.4(P<0.05)。结论采用本研究所涉改良限制性输血策略或可更安全、有效指导临床急诊输血,值得临床进一步研究。
