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Electron G-Factor Anomaly and the Charge Thickness
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作者 Arlen Young 《Journal of Modern Physics》 2024年第4期435-447,共13页
The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, ref... The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, referred to as the g-factor anomaly. This anomaly has been calculated theoretically as a power series of the fine structure constant. This document shows that the anomaly is the result of the electron charge thickness. If the thickness were to be zero, g = 2 exactly, and there would be no anomaly. As the thickness increases, the anomaly increases. An equation relating the g-factor and the surface charge thickness is presented. The thickness is calculated to be 0.23% of the electron radius. The cause of the anomaly is very clear, but why is the charge thickness greater than zero? Using the model of the interior structure of the electron previously proposed by the author, it is shown that the non-zero thickness, and thus the g-factor anomaly, are due to the proposed positive charge at the electron center and compressibility of the electron material. The author’s previous publication proposes a theory for splitting the electron into three equal charges when subjected to a strong external magnetic field. That theory is revised in this document, and the result is an error reduced to 0.4% in the polar angle where the splits occur and a reduced magnetic field required to cause the splits. 展开更多
关键词 Electron g-factor Anomaly Electron Charge Thickness Electron Positive Charge Electron Mass Thickness Electron Fractionalization Splitting the Electron Electron Compressibility Factor
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Theoretical calculations on Landé g-factors and quadratic Zeeman shift coefficients of nsnp ^(3)P_(0)^(o) clock states in Mg and Cd optical lattice clocks
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作者 卢本全 常宏 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第1期278-285,共8页
The study of magnetic field effects on the clock transition of Mg and Cd optical lattice clocks is scarce.In this work,the hyperfine-induced Landég-factors and quadratic Zeeman shift coefficients of the nsnp ^(3)... The study of magnetic field effects on the clock transition of Mg and Cd optical lattice clocks is scarce.In this work,the hyperfine-induced Landég-factors and quadratic Zeeman shift coefficients of the nsnp ^(3)P_(0)^(o) clock states for ^(111,113)Cd and ^(25)Mg were calculated by using the multi-configuration Dirac–Hartree–Fock theory.To obtain accurate values of these parameters,the impact of electron correlations and furthermore the Breit interaction and quantum electrodynamical effects on the Zeeman and hyperfine interaction matrix elements,and energy separations were investigated in detail.We also estimated the contributions from perturbing states to the Landég-factors and quadratic Zeeman shift coefficients concerned so as to truncate the summation over the perturbing states without loss of accuracy.Our calculations provide important data for estimating the first-and second-order Zeeman shifts of the clock transition for the Cd and Mg optical lattice clocks. 展开更多
关键词 optical lattice clock hyperfine-induced Landég-factor quadratic Zeeman shift coefficient Mg and Cd
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The Real Reason Why the Electron’s Bare g-Factor Is 2 Times Classical 被引量:1
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作者 Donald Bowen 《Journal of Modern Physics》 2016年第10期1200-1209,共10页
When analyzing an Electron’s orbit’s and movements, a “classical” bare g-factor of “1” must be used, but when analyzing just the Electron itself, a bare g-factor and gyromagnetic ratio of twice the “classical”... When analyzing an Electron’s orbit’s and movements, a “classical” bare g-factor of “1” must be used, but when analyzing just the Electron itself, a bare g-factor and gyromagnetic ratio of twice the “classical” value is needed to fit reality. Nobody has fully explained this yet. By examining the electromagnetic wave nature of the electron, it is possible to show a simple reason why its bare g-factor must be 2, without resorting to superluminal velocities or dismissing it as mystically intrinsic. A simple charged electromagnetic wave loop (CEWL) model of the electron that maintains the same electromagnetic wave nature as the high-energy photons from which electron-positron pairs form, will have exactly half of its energy in the form of magnetic energy who’s field lines are perpendicular to the direction of the charge rotation, which leads to the conclusion that only half of the electron’s electromagnetic mass is rotational mass, from which it is easy to calculate a bare g-factor of 2 using Feynman’s equation for the electron’s g-factor. 展开更多
关键词 Electron g-factor Magnetic Moment Spin Angular Momentum Magnetic Energy Charged Electromagnetic Wave Loop CEWL Pair Production General Relativity Mass de Broglie Wave
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The g-factors and magnetic rotation in ^(82)Rb
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作者 袁大庆 郑永男 +9 位作者 左翼 范平 周冬梅 吴晓光 竺礼华 李广生 许国基 樊启文 张锡珍 朱升云 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第6期207-212,共6页
The g-factors of the intra-band states 12,13,14,15 in a magnetic-rotational band built on the 11 state in 82 Rb are measured for the first time by using a transient magnetic field-ion implantation perturbed angular di... The g-factors of the intra-band states 12,13,14,15 in a magnetic-rotational band built on the 11 state in 82 Rb are measured for the first time by using a transient magnetic field-ion implantation perturbed angular distribution (TMF-IMPAD) method.The magnetic-rotational band in 82 Rb is populated by the 60 Ni(27 Al,4pn) 82 Rb reaction,and the time-integral Larmor precessions are measured after recoil implantation into a polarized Fe foil.The calculation of g-factors is also carried out in terms of a semi-classical model of independent particle angular momentum coupling on the basis of the four-quasiparticle configuration π(g 9/2) 2  π(p 3/2,f 5/2)  ν (g 9/2).The measured and calculated g-factors are in good agreement with each other.The g-factors and deduced shear angles decrease with the increase of spin along the band.This clearly illustrates the shear effect of a step-by-step alignment of the valence protons and neutrons in magnetic rotation.The semi-classical calculation also shows that the alignment of the valence neutron angular momentum is faster than that of the valence protons,which results in a decrease of g-factors with increasing spin.The present results provide solid evidence of the shear mechanism of magnetic rotation. 展开更多
关键词 82 Rb magnetic rotation g-factor TMF-IMPAD
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Theoretical study of the hyperfine interaction constants, Landé g-factors, and electric quadrupole moments for the low-lying states of the 61Niq+(q=11,12,14,and 15) ions
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作者 张婷贤 张永慧 +1 位作者 李承斌 史庭云 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第1期65-72,共8页
Highly charged nickel ions have been suggested as candidates for the ultra-precise optical clock, meanwhile the relevant experiment has been carried out. In the framework of the multiconfiguration Dirac–Hartree–Fock... Highly charged nickel ions have been suggested as candidates for the ultra-precise optical clock, meanwhile the relevant experiment has been carried out. In the framework of the multiconfiguration Dirac–Hartree–Fock(MCDHF)method, we calculated the hyperfine interaction constants, the Landég-factors, and the electric quadrupole moments for the low-lying states in the 61Ni11+,61Ni12+,61Ni14+, and61Ni15+ ions. These states are clock states of the selected clock transitions in highly charged nickel ions(see Fig. 1). Based on discussing the effects of the electron correlations, the Breit interaction, and quantum electrodynamics(QED) effect on these physical quantities, reasonable uncertainties were obtained for our calculated results. In addition, the electric quadrupole frequency shifts and the Zeeman frequency shifts of the clock transitions concerned were analyzed. 展开更多
关键词 hyperfine interaction Landég-factors electric quadrupole moment multiconfiguration Dirac-Hartree–Fock(MCDHF)method
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复杂光机系统综合性能评估方法
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作者 葛成良 《太赫兹科学与电子信息学报》 2024年第1期75-79,86,共6页
作为涉及光、机、电、控、热、气、液等多个领域的复杂光机系统,如何对其进行综合性能评估一直是难以解决的关键技术问题。针对该问题,通过分层分析并结合熵值、灰色和模糊评估等方法,提出了能够直观反映复杂光机系统的评估因子,即G因... 作为涉及光、机、电、控、热、气、液等多个领域的复杂光机系统,如何对其进行综合性能评估一直是难以解决的关键技术问题。针对该问题,通过分层分析并结合熵值、灰色和模糊评估等方法,提出了能够直观反映复杂光机系统的评估因子,即G因子。通过G因子,可直观地对复杂光机系统的综合性能进行评估,并可对比不同光机系统的综合性能;同时在评估过程中,也可对复杂光机系统的某个或几个关键参数进行对比分析。G因子提供了一种能够反映复杂光机系统综合性能的直观参数,为复杂光机系统的综合性能评估及相关系统研制提供了技术支撑。 展开更多
关键词 G因子 性能评估 复杂光机系统 指标集 权重因子
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Anisotropies of the g-factor tensor and diamagnetic coefficient in crystal-phase quantum dots in InP nanowires 被引量:1
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作者 Shiyao Wu Kai Peng +17 位作者 Sergio Battiato Valentina Zannier Andrea Bertoni Guido Goldoni Xin Xie Jingnan Yang Shan Xiao Chenjiang Qian Feilong Song Sibai Sun Jianchen Dang Yang Yu Fabio Beltram Lucia Sorba Ang Li Bei-bei Li Francesco Rossella Xiulai Xu 《Nano Research》 SCIE EI CAS CSCD 2019年第11期2842-2848,共7页
Crystal-phase low-dimensional structures offer great potential for the implementation of photonic devices of interest for quantum information processing.In this context,unveiling the fundamental parameters of the crys... Crystal-phase low-dimensional structures offer great potential for the implementation of photonic devices of interest for quantum information processing.In this context,unveiling the fundamental parameters of the crystal phase structure is of much relevance for several applications.Here,we report on the anisotropy of the g-factor tensor and diamagnetic coefficient in wurtzite/zincblende(WZ/ZB)crystal-phase quantum dots(QDs)realized in single InP nanowires.The WZ and ZB alternating axial sections in the NWs are identified by high-angle annular dark-field scanning transmission electron microscopy.The electron(hole)g-factor tensor and the exciton diamagnetic coefficients in WZ/ZB crystal-phase QDs are determined through micro-photoluminescence measurements at low temperature(4.2 K)with different magnetic field configurations,and rationalized by invoking the spin-correlated orbital current model.Our work provides key parameters for band gap engineering and spin states control in crystal-phase low-dimensional structures in nanowires. 展开更多
关键词 g-factor tensor diamagnetic coefficient crystal-phase quantum dot InP NWs
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Study of magnetic-rotation in ^(82)Rb byg-factor measurements
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作者 袁大庆 郑永男 +10 位作者 左翼 范平 周冬梅 刘猛 吴晓光 竺礼华 李广生 许国基 樊启文 张锡珍 朱升云 《Chinese Physics C》 SCIE CAS CSCD 2009年第S1期188-190,共3页
Magnetic rotation in 82Rb has been investigated for the first time by g-factor measurement of intra-band states of the magnetic-rotational band built on the 11- state. The g-factors were measured by a TMF-IMPAD method... Magnetic rotation in 82Rb has been investigated for the first time by g-factor measurement of intra-band states of the magnetic-rotational band built on the 11- state. The g-factors were measured by a TMF-IMPAD method and calculated by a semi-classical model of independent particle angular momentum coupling assumption. The g-factors and deduced shears angles decrease with the increasing of spin along the band, illustrating a step-by-step alignment of the valence protons and neutrons. The rapid alignment of the valence neutrons leads to a decrease of g-factors. The present results vividly reveal the shears mechanism of magnetic rotation. 展开更多
关键词 82Rb MAGNETIC ROTATION shears MECHANISM g-factor
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Proton alignment in ^(82)Sr investigated by g-factor measurements
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作者 范平 袁大庆 +9 位作者 左翼 郑永男 周冬梅 吴晓光 李广生 竺礼华 许国基 樊启文 张锡珍 朱升云 《Chinese Physics C》 SCIE CAS CSCD 2009年第S1期206-208,共3页
The proton alignment in 82Sr has been investigated by the g-factor measurements of the ground state rotational band levels up to spin I = 8+. The g-factors were measured by a transient-magnetic-field ion implantation ... The proton alignment in 82Sr has been investigated by the g-factor measurements of the ground state rotational band levels up to spin I = 8+. The g-factors were measured by a transient-magnetic-field ion implantation perturbed angular distribution method. The obtained g-factors increase with the increasing of spin along the band and clearly show the g9/2 proton alignment that starts at I =6+. 展开更多
关键词 g-factor PROTON ALIGNMENT TMF-IMPAD 82Sr
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The orbital g-factor and related sum rules 被引量:2
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作者 BENTZ Wolfgang ARIMA Akito 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2011年第2期194-197,共4页
The renormalization of the orbital g-factor in nuclei is discussed on the basis of gauge invariance.The relation of the orbital g-factor to the integrated E1 photoabsorption cross section is reviewed,and its relation ... The renormalization of the orbital g-factor in nuclei is discussed on the basis of gauge invariance.The relation of the orbital g-factor to the integrated E1 photoabsorption cross section is reviewed,and its relation to the M1 sum rule for the scissors mode of deformed nuclei is examined. 展开更多
关键词 求和规则 轨道 因子和 光吸收截面 G因子 重整化 细胞核 供应量
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肝癌组织中GPSM2、TGF-β1蛋白表达水平及临床意义
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作者 霍亮 骆杨 冯海林 《实用癌症杂志》 2024年第3期406-410,共5页
目的 探讨肝癌组织G蛋白信号调节蛋白(GPSM)2、转化生长因子1(TGF-β1)蛋白表达与临床病理参数及预后的关系。方法 选取原发性肝癌患者80例,取手术切除的肝癌组织和癌旁正常组织。采用免疫组织化学染色法检测GPSM2、TGF-β1在癌组织和... 目的 探讨肝癌组织G蛋白信号调节蛋白(GPSM)2、转化生长因子1(TGF-β1)蛋白表达与临床病理参数及预后的关系。方法 选取原发性肝癌患者80例,取手术切除的肝癌组织和癌旁正常组织。采用免疫组织化学染色法检测GPSM2、TGF-β1在癌组织和癌旁正常组织中的表达差异,分析癌组织中GPSM2、TGF-β1表达水平与临床病理参数及预后的关系。结果 肝癌组织中GPSM2、TGF-β1高表达率分别为71.25%、82.50%,高于癌旁正常组织的18.75%、13.75%(P<0.05)。GPSM2在分化程度低的肝癌组织中高表达率较高(P<0.05),TGF-β1在分化程度低、有血管转移的肝癌组织中高表达率较高(P<0.05)。生存曲线显示,GPSM2、TGF-β1低表达患者的累积生存率(77.27%、85.71%)高于高表达患者(47.37%、48.48%),差异具有统计学意义(P<0.05)。结论 GPSM2、TGF-β1在肝癌组织中高表达率较高,其表达水平与分化程度密切相关,GPSM2、TGF-β1高表达患者预后较差。 展开更多
关键词 原发性肝癌 G蛋白信号调节蛋白2 转化生长因子1 临床病理参数 预后
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Magnetic moments and g-factors in odd-A Ho isotopes
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作者 E.Tabar H.Yakut +2 位作者 A.A.Kuliev H.Quliyev G.Hosgor 《Chinese Physics C》 SCIE CAS CSCD 2017年第7期52-60,共9页
The ground-state magnetic moment, g K factor and quenching spin gyromagnetic ratio have been calculated using the microscopic method based on the Quasiparticle Phonon Nuclear Model(QPNM) for155-169 Ho nuclei for the f... The ground-state magnetic moment, g K factor and quenching spin gyromagnetic ratio have been calculated using the microscopic method based on the Quasiparticle Phonon Nuclear Model(QPNM) for155-169 Ho nuclei for the first time. It is shown that the residual spin-spin interactions are responsible for the core polarization,and because of the core polarization the spin gyromagnetic factors are quenched. By considering the core polarization effects, a satisfactory agreement is obtained for the computed ground state g K factor, which gives an intrinsic contribution to the magnetic moments. In order to assess the collective contribution to the magnetic moments, the rotational gyromagnetic factors g R have been also calculated within the cranking approximation using the single particle wave function of the axially symmetric Woods-Saxon potential. For the ground-state magnetic moments of odd-proton155-165 Ho nuclei, a good description of the experimental data is obtained with an accuracy of 0.01–0.1μN. From systematic trends, the quenching spin gyromagnetic factor, g K factor and magnetic moment have also been theoretically predicted for167,169 Ho where there is no existing experimental data. 展开更多
关键词 基态磁矩 G因子 O同位素 自旋相互作用 粒子波函数 极化效应 实验数据 发展趋势
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泉州地震台g-Phone重力仪观测资料干扰因素分析
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作者 陈珊桦 蔡佩蕊 +2 位作者 陈新兴 谢文杰 王建新 《地震科学进展》 2023年第4期159-164,共6页
通过对泉州地震台g-Phone重力仪自正式运行以来观测资料的干扰因素进行总结,发现数采死机对数据影响较小,但断电造成的仪器内部温度的改变会导致原始数据漂移,从而降低数据的内在质量,建议应尽量避免人为操作如断电等造成的内部温度变化... 通过对泉州地震台g-Phone重力仪自正式运行以来观测资料的干扰因素进行总结,发现数采死机对数据影响较小,但断电造成的仪器内部温度的改变会导致原始数据漂移,从而降低数据的内在质量,建议应尽量避免人为操作如断电等造成的内部温度变化;台风影响使得数据噪声变大,表现为观测曲线变粗,呈纺锤状。希望研究结果可以为进一步利用重力资料提取地震前兆信息提供一定的参考。 展开更多
关键词 重力观测 干扰因素 g-Phone重力仪
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IGHG1对人急性髓系白血病THP-1细胞增殖、凋亡的影响 被引量:1
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作者 高鑫 储李婧 陈天平 《中国实验血液学杂志》 CAS CSCD 北大核心 2023年第5期1263-1271,共9页
目的:探讨免疫球蛋白G1重链恒定区(IGHG1)对急性髓系白血病(AML)细胞系THP-1细胞增殖、凋亡的影响及其可能的作用机制。方法:体外培养人AML THP-1细胞,分为对照(正常培养的THP-1细胞)、pcDNA3.1[转染IGHG1过表达(pcDNA3.1-IGHG1)阴性对... 目的:探讨免疫球蛋白G1重链恒定区(IGHG1)对急性髓系白血病(AML)细胞系THP-1细胞增殖、凋亡的影响及其可能的作用机制。方法:体外培养人AML THP-1细胞,分为对照(正常培养的THP-1细胞)、pcDNA3.1[转染IGHG1过表达(pcDNA3.1-IGHG1)阴性对照质粒的THP-1细胞]、pcDNA3.1-IGHG1(转染pcDNA3.1-IGHG1的THP-1细胞)、LY364947[转化生长因子-β(TGF-β)/信号转导蛋白(Smad)抑制剂LY36494720μmol/L处理THP-1细胞)]、si-NC[转染IGHG1小干扰RNA(IGHG1-siRNA)阴性对照的THP-1细胞]、si-IGHG1(转染IGHG1-siRNA的THP-1细胞)和si-IGHG1+LY364947(IGHG1-siRNA和LY364947共同处理THP-1细胞)共7组。荧光定量PCR法检测各组THP-1细胞中IGHG1和免疫球蛋白G(IgG)mRNA的表达;CCK-8法检测各组THP-1细胞增殖活力;流式细胞术检测各组THP-1细胞凋亡率和细胞周期变化;蛋白印迹法检测各组THP-1细胞增殖、凋亡及TGF-β/Smad信号通路相关蛋白的表达。结果:与对照组相比,过表达IGHG1后THP-1细胞中IGHG1和IgG mRNA表达、细胞增殖活力、S期的细胞比例、细胞周期蛋白D1(Cyclin D1)、B细胞淋巴瘤-2(Bcl-2)、IgG、TGF-β1、磷酸化Smad3(p-Smad3)/Smad3蛋白表达均显著升高(P<0.05),细胞凋亡率、G_(0)/G_(1)期的细胞比例、p21、Bcl-2相关X蛋白(Bax)、半胱氨酸天冬氨酸蛋白酶-3(Caspase-3)蛋白表达均显著降低(P<0.05)。抑制TGF-β/Smad信号通路或沉默IGHG1后THP-1细胞中IGHG1和IgG mRNA表达、细胞增殖活力、S期的细胞比例、Cyclin D1、Bcl-2、IgG、TGF-β1、p-Smad3/Smad3蛋白表达均显著降低(P<0.05),细胞凋亡率、G_(0)/G_(1)期的细胞比例、p21、Bax、Caspase-3蛋白表达均显著升高(P<0.05);且与沉默IGHG1相比,IGHG1基因沉默和TGF-β/Smad通路抑制共同处理的THP-1细胞中IGHG1和IgG mRNA表达、细胞增殖活力、S期的细胞比例、Cyclin D1、Bcl-2、IgG、TGF-β1、p-Smad3/Smad3蛋白表达均显著降低(P<0.05),细胞凋亡率、G_(0)/G_(1)期的细胞比例、p21、Bax、Caspase-3蛋白表达均显著升高(P<0.05)。结论:沉默IGHG1基因可下调IgG的表达,抑制人AML THP-1细胞增殖,阻滞细胞周期进程,并诱导细胞凋亡;其作用机制可能与抑制TGF-β/Smad通路的激活有关。 展开更多
关键词 免疫球蛋白G1重链恒定区 急性髓系白血病THP-1细胞 免疫球蛋白G 凋亡 增殖 转化生长因子-β/信号转导蛋白
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慢性乙型肝炎患者口服抗病毒药物依从性与生活质量的相关性及其影响因素 被引量:1
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作者 李佳鑫 王清 陈雁 《中国医药科学》 2023年第6期126-130,共5页
目的分析慢性乙型肝炎(CHB)患者口服核苷(酸)类似物进行抗病毒治疗的依从性的影响因素及用药依从性与生活质量的相关性。方法采用便利抽样法选取2021年3—7月在南京鼓楼医院肝炎门诊接受抗病毒治疗的CHB患者191例,应用一般资料调查表、M... 目的分析慢性乙型肝炎(CHB)患者口服核苷(酸)类似物进行抗病毒治疗的依从性的影响因素及用药依从性与生活质量的相关性。方法采用便利抽样法选取2021年3—7月在南京鼓楼医院肝炎门诊接受抗病毒治疗的CHB患者191例,应用一般资料调查表、Morisky用药依从性量表(MMAS-8)和慢性肝病问卷(CLDQ)对其用药依从性和生活质量进行调查,采用SPSS 21.0软件进行统计分析。结果191例CHB患者MMAS-8平均得分为(6.54±1.45)分,CLDQ平均得分为(168.23±20.77)分。统计学分析结果表明,用药依从性与生活质量显著正相关。MMAS-8得分在居住地、当前药物治疗时长、当前药物治疗方案及随访次数方面差异有统计学意义(P<0.05);居住地为城市、随访≥3次是用药依从性的保护因素(P<0.05),当前药物治疗时长≥6个月是用药依从性的独立危险因素(P<0.05)。结论CHB患者用药依从性处于中等水平,用药依从性影响生活质量。医护人员应重点评估行抗病毒治疗的CHB患者的居住地、当前药物治疗时长和随访次数,帮助患者达到并保持高度用药依从性,提高生活质量。 展开更多
关键词 慢性乙型肝炎 抗病毒治疗 依从性 影响因素 生活质量
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结直肠癌中NCAPH、AGGF1及TM4SF1的表达及与预后的相关性
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作者 王磊 薛松 +1 位作者 单长凤 王亚男 《临床与病理杂志》 CAS 2023年第6期1126-1135,共10页
目的:探讨结直肠癌(colorectal cancer,CRC)中非染色体结构维持蛋白凝缩蛋白复合体I亚单位H(non-SMC condensin I complex subunit H,NCAPH)、G补缀FHA域血管新生因子1(angiogenic factor with G and FHA domains 1,AGGF1)及跨膜4L六家... 目的:探讨结直肠癌(colorectal cancer,CRC)中非染色体结构维持蛋白凝缩蛋白复合体I亚单位H(non-SMC condensin I complex subunit H,NCAPH)、G补缀FHA域血管新生因子1(angiogenic factor with G and FHA domains 1,AGGF1)及跨膜4L六家族成员1(transmembrane-4-L-six-family-1,TM4SF1)蛋白质表达之间的关系及临床意义。方法:收集145例CRC术后标本和30例癌旁正常黏膜组织标本,采用免疫组织化学法检测CRC和癌旁正常黏膜组织中NCAPH、AGGF1及TM4SF1蛋白质的表达情况,分析其表达与各种临床病理因素的关系以及三者之间的相关性。结果:在CRC和癌旁组织中,NCAPH、AGGF1及TM4SF1的阳性表达率分别为55.2%、53.1%、60.7%和3.3%、6.6%、0,差异均有统计学意义(均P<0.001)。3种蛋白质的表达均与CRC的组织学分化和TNM分期有关(均P<0.001);NCAPH和TM4SF1的表达均与CRC的淋巴结转移有关(均P<0.05);NCAPH和AGGF1的表达均与CRC组织脉管侵犯有关(均P<0.05);AGGF1和TM4SF1的表达均与CRC的肿瘤浸润深度有关(均P<0.01)。TM4SF1的表达分别与NCAPH和AGGF1的表达呈正相关(r值分别为0.311和0.517,均P<0.001);同时,AGGF1与NCAPH的表达亦呈正相关(r=0.291,P=0.001)。Kaplan-Meier生存分析表明:NCAPH、AGGF1及TM4SF1的表达上调均与患者的生存率有关,NCAPH、AGGF1及TM4SF1阳性的患者生存率明显低于三者阴性患者(均P<0.05)。多因素分析表明:TNM分期、NCAPH、AGGF1及TM4SF1的表达和肿瘤脉管侵犯均是影响CRC根治术后患者预后的独立因素(均P<0.05)。结论:CRC组织中NCAPH、AGGF1及TM4SF1的表达上调与CRC的分化程度、转移和预后等因素相关,这些指标的联合检测可能作为判断CRC进展及患者预后的重要指标。 展开更多
关键词 结直肠癌 非染色体结构维持蛋白凝缩蛋白复合体Ⅰ亚单位H G补缀FHA域血管新生因子1 跨膜4L六家族成员1 预后
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山东某医院肝移植受者术后弓形虫感染现状调查
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作者 白文叶 薛宝梅 +3 位作者 王中军 张翔雁 李永欣 田润华 《青岛大学学报(医学版)》 CAS 2023年第2期246-249,共4页
目的分析山东某医院近3年肝移植受者移植后血清弓形虫抗体含量及常见感染接触史,了解本地区肝移植受者术后弓形虫感染相关因素。方法选取2015年6月—2018年11月在青岛大学附属医院接受肝移植手术、术前弓形虫抗体检测阴性且术后自愿接... 目的分析山东某医院近3年肝移植受者移植后血清弓形虫抗体含量及常见感染接触史,了解本地区肝移植受者术后弓形虫感染相关因素。方法选取2015年6月—2018年11月在青岛大学附属医院接受肝移植手术、术前弓形虫抗体检测阴性且术后自愿接受弓形虫抗体检测的210例病人作为病例组,同期随机选取与病例组年龄、性别相匹配的本院健康查体成人210例作为对照组。采用化学发光法对所有受试者血清弓形虫抗体(IgG和IgM)进行定量测定,并进行流行病学问卷调查。结果病例组及对照组血清弓形虫抗体阳性率分别为29.5%和9.5%,两组比较差异有统计学意义(χ^(2)=26.73,P<0.01)。肝移植受者术后弓形虫感染与养猫、生吃蔬菜、接触动物粪便及化疗史、接受抗肿瘤靶向治疗史有关(χ^(2)=4.23~30.10,P<0.05)。结论山东青岛地区肝移植受者术后弓形虫感染率明显高于健康成人,这可能与移植者免疫力下降及某些生活习惯有关。临床应定期监测肝移植病人血清弓形虫抗体含量,加强宣讲,以预防和控制移植后弓形虫感染。 展开更多
关键词 肝移植 弓形虫病 免疫球蛋白M 免疫球蛋白G 危险因素
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QuantiFERON-TB GOLD对活动性结核病的诊断价值及影响因素分析
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作者 王移欢 段绍琪 +2 位作者 孙杰 陈曦 刘凤君 《医学理论与实践》 2023年第7期1085-1088,1084,共5页
目的:探讨γ干扰素释放实验QuantiFERON-TB GOLD(QFT-G)对活动性结核病的诊断价值及影响因素。方法:回顾性分析2018年7月—2019年7月在川北医学院附属医院行QFT-G检测的住院患者的资料,分析QFT-G在活动性结核病诊断中的敏感性、特异性... 目的:探讨γ干扰素释放实验QuantiFERON-TB GOLD(QFT-G)对活动性结核病的诊断价值及影响因素。方法:回顾性分析2018年7月—2019年7月在川北医学院附属医院行QFT-G检测的住院患者的资料,分析QFT-G在活动性结核病诊断中的敏感性、特异性及影响因素。结果:(1)活动性结核QFT-G的敏感度、特异度、阳性预测值及阴性预测值分别为80.04%、59.30%、71.46%、81.20%。陈旧性结核QFT-G阳性率为66.39%。(2)年龄>61岁(OR=2.463,95%CI=1.026~5.917,P=0.044)、实体肿瘤合并感染(OR=2.813,95%CI=1.144~6.918,P=0.024)和风湿性疾病(OR=6.122,95%CI=2.132~17.576,P=0.001)分别是QFT-G假阴性、假阳性和不确定结果的独立影响因素。结论:(1)QFT-G敏感度较好,但特异性不理想,对于结核的排除价值更高。(2)QFT-G不适合用于鉴别活动性及陈旧性结核。(3)QFT-G用于年龄>61岁、实体肿瘤合并感染、风湿性疾病患者诊断结核时需注意假阴性、假阳性和不确定结果。 展开更多
关键词 结核 γ干扰素释放实验 QFT-G 影响因素
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自拟除痹温经汤对寒湿痹阻型类风湿关节炎患者关节肿胀和免疫功能的影响 被引量:1
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作者 杨盼 杨元元 《药品评价》 CAS 2023年第2期199-202,共4页
目的 探究自拟除痹温经汤对寒湿痹阻型类风湿关节炎患者关节肿胀和免疫功能的影响。方法 选取2019年10月至2021年9月于驻马店市中心医院治疗类风湿关节炎的患者136例,根据乱数表法随机分为中药组与常规组各68例。常规组给予西医常规治疗... 目的 探究自拟除痹温经汤对寒湿痹阻型类风湿关节炎患者关节肿胀和免疫功能的影响。方法 选取2019年10月至2021年9月于驻马店市中心医院治疗类风湿关节炎的患者136例,根据乱数表法随机分为中药组与常规组各68例。常规组给予西医常规治疗,同时中药组增加自拟除痹温经汤治疗,两组均连续治疗4周。对比治疗后两组临床疗效;治疗前后两组中医证候积分(关节冷痛、关节麻木、关节屈伸不利),关节功能(关节压痛数、关节肿胀数、晨僵时间),免疫功能[免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、补体3(C3)、类风湿因子(RF)],对比治疗期间两组不良反应发生率。结果 治疗4周后,中药组临床疗效高于常规组(P<0.05);两组中医证候积分较治疗前均降低(P<0.05),且中药组低于同期常规组(P<0.05);两组关节压痛数、关节肿胀数、晨僵时间较治疗前均降低(P<0.05),且中药组低于同期常规组(P<0.05);两组IgA、IgG、IgM、RF水平较治疗前均降低(P<0.05),且中药组低于同期常规组(P<0.05),两组C3水平较治疗前均升高(P<0.05),且中药组高于同期常规组(P<0.05)治疗期间两组不良反应发生率差异无统计学意义(P>0.05)。结论 自拟除痹温经汤治疗类风湿关节炎患者效果显著,能改善临床症状,减轻关节肿痛,纠正免疫紊乱,具有一定安全性。 展开更多
关键词 关节炎 类风湿 除痹温经汤 免疫球蛋白G 关节功能 类风湿因子
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