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基于脾不行津、肾关失守探讨慢性萎缩性胃炎中医病机特点
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作者 孙洁纯 潘以丰 《新中医》 CAS 2024年第1期200-203,共4页
慢性萎缩性胃炎(CAG)是炎-癌转化的重要环节,中医药在中医理论的基础上对本病进行辨证论治。笔者通过浅析“脾不能为胃行其津液”“肾为胃之关”的中医理论来探讨CAG的病因病机,总结得出其病机为本虚标实,可从脾肾亏虚角度进行论治,兼... 慢性萎缩性胃炎(CAG)是炎-癌转化的重要环节,中医药在中医理论的基础上对本病进行辨证论治。笔者通过浅析“脾不能为胃行其津液”“肾为胃之关”的中医理论来探讨CAG的病因病机,总结得出其病机为本虚标实,可从脾肾亏虚角度进行论治,兼顾瘀、毒、湿等标实之邪。 展开更多
关键词 慢性萎缩性胃炎 病因病机 脾不行津、肾关失守 五行生克
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Cell Cycle Arrest Mediates Global DNA Methylation Patterns in Normal Human Keratinocytes, Epidermoid Carcinoma Cells and Murine Embryonic Fibroblasts
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作者 John J. Wille Jong Y. Park 《Journal of Cancer Therapy》 2013年第1期199-207,共9页
The 5-methylationcytosine (5-MC) DNA content of murine embryonic fibroblasts arrested in G1 by four growth conditions (Gc, Gn, Gd, and Gs) were hypermethylated relative to rapidly growing (RG) fibroblasts. Normal huma... The 5-methylationcytosine (5-MC) DNA content of murine embryonic fibroblasts arrested in G1 by four growth conditions (Gc, Gn, Gd, and Gs) were hypermethylated relative to rapidly growing (RG) fibroblasts. Normal human keratinocytes (NHK) arrested in G1 by suspension were hypermethylated relative to RG cultures. Four RG cultures of epidermoid carcinoma cells (ECC) were hypomethylated relative to RG NHK cultures, and two cultures (SCC25 and A431) were further hypomethylated by SUS-induced arrest. Linear regression analyses established a positive linear correlation between growth rate and 5-MC content for three murine fibroblasts lines, and a negative correlation for both NHK and ECC lines. 展开更多
关键词 ANOIKIS Epitheliod Carcinoma Cells Cell Cycle DNA METHYLATION G1 Phase restriction Points
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